Manipulating the amyloid-β aggregation pathway with chemical chaperones

Journal of Biological Chemistry

Volumn 274, Issue 46, 1999, Pages 32970-32974

  Yang, Dun Sheng ^a   Yip, Christopher M ^b   Huang, T H Jackson ^b,c   Chakrabartty, Avijit ^b,c   Fraser, Paul E ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CHAPERONE; GLYCEROL; TRIMETHYLAMINE OXIDE;

ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; ELECTRON MICROSCOPY; HYDRATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SOLUBILITY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CIRCULAR DICHROISM; FLUORESCENT DYES; GLYCEROL; HUMANS; METHYLAMINES; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON; MOLECULAR CHAPERONES; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SOLUBILITY; SPECTROMETRY, FLUORESCENCE;

EID: 0032755251     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.46.32970     Document Type: Article

References (35)

1. Selkoe, D. J. (1997) Science 276, 630-631
2. Kisilevsky, R., and Fraser, P. E. (1997) Crit. Rev. Biochem. Mol. Biol. 32, 361-404
3. Inouye, H., Fraser, P. E., and Kirschner, D. A. (1993) Biophys. J. 64, 502-519
4. Jarrett, J. T., Berger, E. P., and Lansbury, P. T., Jr. (1993) Biochemistry 32, 4693-4697
5. Lomakin, A., Teplow, D. B., Kirschner, D. A., and Benedek, G. B. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7942-7947
6. Stine, W. B., Jr., Snyder, S. W., Ladror, U. S., Wade, W. S., Miller, M. F., Perun, T. J., Holzman, T. F., and Krafft, G. A. (1996) J. Protein Chem. 15, 193-203
7. Harper, J. D., Wong, S. S., Lieber, C. M., and Lansbury, P. T. (1997) Chem. Biol. 4, 119-125
8. Walsh, D. M., Lomakin, A., Benedek, G. B., Condron, M. M., and Teplow, D. B. (1997) J. Biol. Chem. 272, 22364-22372
9. Sunde, M., Serpell, L. C., Bartlam, M., Fraser, P. E., Pepys, M. B., and Blake, C. C. F. (1997) J. Mol. Biol. 273, 729-739
10. Blake, C. C. F., and Serpell, L. (1996) Structure 4, 989-998
11. Schmechel, D. E., Saunders, A. M., Strittmatter, W. J., Crain, B. J., Hulette, C. M., Joo, S. H., Pericak-Vance, M. A., Goldgaber, D., and Roses, A. D. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 9649-9653
12. Cook, D. G., Forman, M. S., Sung, J. C., Leight, S., Kolson, D. L., Iwatsubo, T., Lee, V. M., and Doms, R. W. (1997) Nat. Med. 3, 1021-1023
13. Hartmann, T., Bieger, S. C., Bruhl, B., Tienari, P. J., Ida, N., Allsop, D., Roberta, G. W., Masters, C. L., Dotti, C. G., Unsicker, K., and Beyreuther, K. (1997) Nat. Med. 3, 1016-1020
14. Wild-Bode, C., Yamazaki, T., Capell, A., Leimer, U., Steiner, H., Ihara, Y., and Haass, C. (1997) J. Biol. Chem. 272, 16085-16088
15. Skovronsky, D. M., Doms, R. W., and Lee, V. M. (1998) J. Cell Biol. 141, 1031-1039
16. Burg, M. B. (1995) Am. J. Physiol. 268, 983-996
17. Wang, A., and Bolen, D. W. (1997) Biochemistry 36, 9101-9108
18. Timasheff, S. N. (1993) Annu. Rev. Biophys. Biomol. Struct. 22, 67-97
19. Brown, C. R., Hong-Brown, L. Q., and Welch, W. J. (1997) J. Clin. Invest. 99, 1432-1444
20. Sackett, D. L. (1997) Am. J. Physiol. 273, R669-R676
21. McLaurin, J., Franklin, T., Chakrabartty, A., and Fraser, P. E. (1998) J. Mol. Biol. 278, 183-194
22. Huang, T. H. J., Fraser, P. E., and Chakarbartty, A. (1997) J. Mol. Biol. 269, 214-224
23. Harper, J. D., Lieber, C. M., and Lansbury, P. T., Jr. (1997) Chem. Biol. 4, 951-959
24. Garzon-Rodriguez, W., Sepulveda-Becerra, M., Milton, S., and Glabe, C. G. (1997) J. Biol. Chem. 272, 21037-21044
25. Roher, A. E., Chaney, M. O., Kuo, Y. M., Webster, S. D., Stine, W. B., Haverkamp, L. J., Woods, A. S., Cotter, R. J., Tuohy, J. M., Krafft, G. A., Bonnell, B. S., and Emmerling, M. R. (1996) J. Biol. Chem. 271, 20631-20635
26. Kowalewski, T., and Holzman, D. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3688-3693
27. Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., Wals, P., Zhang, C., Finch, C. E., Krafft, G. A., and Klein, W. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6448-6453
28. Evans, K. C., Berger, E. P., Cho, C. G., Weisgraber, K. H., and Lansbury, P. T., Jr. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 763-767
29. Booth, D. R., Sunde, M., Bellotti, V., Robinson, C. V., Hutchinson, W. L., Fraser, P. E., Hawkins, P. N., Dobson, C. M., Radford, S. E., Blake, C. C. F., and Pepys, M. B. (1997) Nature 385, 787-793
30. Lai, Z., Colon, W., and Kelly, J. W. (1996) Biochemistry 35, 6470-6482
31. DebBurman, S. K., Raymond, G. J., Caughey, B., and Lindquist, S. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 13938-13943
32. Tatzelt, J., Prusiner, S. B., and Welch, W. J. (1996) EMBO J. 15, 6363-6373
33. Brown, C. R., Hong-Brown, L. Q., Biwersi, J., Verkman, A. S., and Welch, W. J. (1996) Cell Stress Chaperones 1, 117-125
34. Sato, S., Ward, C. L., Krouse, M. E., Wine, J. J., and Kopito, R. R. (1996) J. Biol. Chem. 271, 635-638
35. Tamarappoo, B. K., and Verkman, A. S. (1998) J. Clin. Invest. 101, 2257-2267