Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease

Journal of Neuroscience

Volumn 25, Issue 42, 2005, Pages 9694-9703

  Chin, Jeannie ^a,b   Palop, Jorge J ^a,b   Puoliväli, Jukka ^a,b,e   Massaro, Catherine ^a   Bien Ly, Nga ^a   Gerstein, Hilary ^a   Scearce Levie, Kimberly ^a   Masliah, Eliezer ^c   Mucke, Lennart ^a,b,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^e Cerebricon Limited   (Finland)

Author keywords

Amyloid ; Arc; Hippocampus; Plasticity; Spatial memory; Striatal enriched phosphatase (STEP)

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CALBINDIN; CYTOSKELETON PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE; PROTEIN ARC; PROTEIN FOS; PROTEIN KINASE FYN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; DENTATE GYRUS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FEMALE; MALE; MEMORY CONSOLIDATION; MOUSE; NEUROMODULATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS C-FYN; SYNAPSES;

EID: 27144489060     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2980-05.2005     Document Type: Article

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