Reactivity of apolipoprotein E4 and amyloid β peptide: Lysosomal stability and neurodegeneration

Journal of Biological Chemistry

Volumn 281, Issue 5, 2006, Pages 2683-2692

  Ji, Zhong Sheng ^a   Müllendorff, Karin ^a   Cheng, Irene H ^a   Miranda, R Dennis ^a   Huang, Yadong ^a,b   Mahley, Robert W ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; BIOLOGICAL MEMBRANES; CELLS; ENZYMES; LIPIDS; NEUROLOGY; PH EFFECTS; RNA;

APOLIPOPROTEIN E4; APOPTOSIS; BAFILOMYCIN; CYTOSOL; LYSOSOMAL STABILITY; LYSOSOMES; NEURODEGENERATION; NEURONAL DEGENERATION; PHOSPHOLIPID VESICLES;

PROTEINS;

AMMONIUM CHLORIDE; AMYLOID BETA PROTEIN; APOLIPOPROTEIN A; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; BAFILOMYCIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; APOLIPOPROTEIN E; LIPOSOME;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; DRUG EFFECT; HUMAN; HUMAN CELL; LYSOSOME; MACROGLIA; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CELL LINE; DEGENERATIVE DISEASE; DIMERIZATION; GENETIC TRANSFECTION; INTRACELLULAR MEMBRANE; METABOLISM; NERVE CELL; PATHOLOGY; TRANSGENIC MOUSE; ULTRASTRUCTURE;

MUS MUSCULUS;

AMYLOID BETA-PROTEIN; ANIMALS; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; APOPTOSIS; CELL LINE; DIMERIZATION; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR MEMBRANES; LIPOSOMES; LYSOSOMES; MICE; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES; NEURONS; TRANSFECTION;

EID: 33645553416     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M506646200     Document Type: Article

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