γ-cleavage is dependent on ζ-cleavage during the proteolytic processing of amyloid precursor protein within its transmembrane domain

Journal of Biological Chemistry

Volumn 280, Issue 45, 2005, Pages 37689-37697

  Zhao, Guojun ^a   Cui, Mei Zhen ^a   Mao, Guozhang ^a   Dong, Yunzhou ^a   Tan, Jianxin ^a   Sun, Longsheng ^a   Xu, Xuemin ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; ENZYME INHIBITION; ENZYME KINETICS; IMMUNOLOGY; MOLECULAR BIOLOGY; PERMSELECTIVE MEMBRANES; PRECIPITATION (CHEMICAL);

Β-AMYLOID PRECURSOR; Γ-SECRETASE INHIBITORS; PROTEOLYTIC PROCESSING; TRANSMEMBRANE DOMAINS;

PROTEINS;

AMYLOID BETA PROTEIN 46; AMYLOID BETA PROTEIN 49; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; CELL PROTEIN; GAMMA SECRETASE INHIBITOR; MEMBRANE PROTEIN; PRESENILIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; RAT;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CARBAMATES; CELL LINE; CELL MEMBRANE; CELL-FREE SYSTEM; DIPEPTIDES; ENDOPEPTIDASES; ENZYME INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY;

ANIMALIA;

EID: 27844441278     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M507993200     Document Type: Article

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