Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1

Journal of Biological Chemistry

Volumn 280, Issue 51, 2005, Pages 41928-41939

  Lu, Huasheng ^a   Dalgard, Clifton L ^a   Mohyeldin, Ahmed ^a   McFate, Thomas ^a   Tait, A Sasha ^a   Verma, Ajay ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENETIC ENGINEERING; HYDROXYLATION; METABOLISM; OXYGEN; PROTEINS; TUMORS;

ANGIOGENESIS; BASAL HIF-1; KREBS CYCLE; NONHYPOXIC STIMULI;

ENZYMES;

2 OXOACID; 2 OXOGLUTARIC ACID; ASCORBIC ACID; CYSTEINE; DIOXYGENASE; FERROUS ION; FUMARIC ACID; GLUCOSE; HISTIDINE; OXALOACETIC ACID; OXYGEN; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PYRUVIC ACID; SUCCINIC ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HIF1; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CANCER CELL; CELL METABOLISM; CELL SURVIVAL; CITRIC ACID CYCLE; CONTROLLED STUDY; ENERGY METABOLISM; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; HYDROXYLATION; HYPOXIA; MALIGNANT TRANSFORMATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ASCORBIC ACID; BASE SEQUENCE; CELL LINE; CYSTEINE; DNA PRIMERS; GLUTATHIONE; GLYCOLYSIS; HISTIDINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; OXALOACETATE; PROCOLLAGEN-PROLINE DIOXYGENASE; PYRUVIC ACID;

EID: 29644442625     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M508718200     Document Type: Article

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