Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors

Journal of Neuroscience

Volumn 26, Issue 36, 2006, Pages 9250-9263

  Mojsilovic Petrovic, Jelena ^a   Jeong, Goo Bo ^a,b   Crocker, Amanda ^a   Arneja, Amrita ^a   David, Samuel ^a   Russell, David ^c   Kalb, Robert G ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b Chungbuk National University College of Medicine   (South Korea)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine A2a receptor; Amyotrophic lateral sclerosis; Brain derived neurotrophic factor; Motoneuron; Transactivation; Trk receptor

Indexed keywords

ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; CEP 4416; COPPER ZINC SUPEROXIDE DISMUTASE; ENPROFYLLINE; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; ISTRADEFYLLINE; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; EXCITOTOXICITY; MOTONEURON; MOTOR NEURON DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; KAINIC ACID; MOTOR NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, ADENOSINE A2A;

EID: 33748497107     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1856-06.2006     Document Type: Article

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