Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors

Cytokine and Growth Factor Reviews

Volumn 13, Issue 1, 2002, Pages 11-17

  Lee, Francis S ^a   Rajagopal, Rithwick ^b   Chao, Moses V ^b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; BDNF; GPCR; NGF; PLC ; Shc

Indexed keywords

ADENOSINE; ADENOSINE A2A RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; ADENYLATE CYCLASE; BRAIN DERIVED NEUROTROPHIC FACTOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; GTP BINDING PROTEINS; GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR; PHOSPHOLIPASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SOMATOMEDIN C; TYROSINE KINASE RECEPTOR;

ANIMAL; ANIMAL CELL; BIOLOGICAL MODEL; CELL SURVIVAL; CHEMISTRY; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; LIGAND BINDING; METABOLISM; NONHUMAN; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SHORT SURVEY; SIGNAL TRANSDUCTION; TRANSACTIVATION; REVIEW;

ANIMAL; GTP-BINDING PROTEINS; HUMAN; LIGANDS; MODELS, BIOLOGICAL; NERVE GROWTH FACTORS; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, TRKA; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANS-ACTIVATION (GENETICS);

EID: 0036006816     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6101(01)00024-7     Document Type: Short Survey

References (36)

1. Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor
2. Epidermal growth factor receptors: Critical mediators of multiple receptor pathways
3. Role of transactivation of the EGF receptor in signalling by G-protein coupled receptors
4. Signal characteristics of G protein -transactivated EGF receptor
5. Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells
6. Distinct calcium-dependent pathways of epidermal growth factor receptor transactivation and PYK2 tyrosine phosphorylation in PC12 cells
7. Structural determinants of neurotrophin action
8. p75 and trk: A two receptor system
9. Neurotrophin signal transduction in the nervous system
10. Bradykinin and nerve growth factor release the capsaicin receptor from Ptdlns(4,5)P2-mediated inhibition
11. Activation of Trk neurotrophin receptors in the absence of neurotrophins
12. Receptors for purines and pyrimidines
13. K-252a inhibits NGF-induced trk proto-oncogene tyrosine phosphorylation and kinase activity
14. The EGF receptor as central transducer of heterologous signaling systems
15. A2B adenosine and P2Y2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney 293 cells
16. Activation of mitogen-activated protein kinase by the A2A-adenosine receptor via a rapl-dependent and via a p21ras-dependent pathway
17. Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary endothelial cells
18. TrkA immunoglobulin-like ligand binding domains inhibit spontaneous activation of the receptor
19. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
20. Transcription-dependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway
21. Neuroprotective role of adenosine in cerebral ischaemia
22. Adenosine receptor ligands: Differences with acute versus chronic treatment
23. Stimulation of expression for the adenosine A2A receptor gene by hypoxia in PC12 cells
24. Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells
25. Functions of the neurotrophins during nervous-system development - What the knockouts are teaching us
26. Regulation of tyrosine kinase cascades by G-protein-coupled receptors
27. Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade
28. Activation and targeting of extracellular signal-regulated kinases by b-arrestin scaffolds
29. Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors
30. The β2-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
31. Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor
32. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
33. Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF
34. Neurotrophins and neuronal plasticity
35. Essential role for TrkB receptors in hippocampus-mediated learning
36. The neurotrophin hypothesis for synaptic plasticity