Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms

Journal of Neuroscience

Volumn 18, Issue 23, 1998, Pages 9673-9684

  Roy, Josée ^a   Minotti, Sandra ^a   Dong, Lichun ^b   Figlewicz, Denise A ^b   Durham, Heather D ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

ALS; Amyotrophic lateral sclerosis; Calbindin; Calcium binding proteins; Culture model; Excitotoxicity; Glutamate receptors; Glutathione; Motor neuron; Neurotoxicity; Oxidative stress; Selective vulnerability; Superoxide dismutase 1

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CALCIUM; CALCIUM BINDING PROTEIN; CALCIUM CHANNEL; COPPER ZINC SUPEROXIDE DISMUTASE; FREE RADICAL; GLUTAMATE RECEPTOR; KAINIC ACID RECEPTOR; NIFEDIPINE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CHANNEL GATING; GENE EXPRESSION; GENE MUTATION; GENETIC PREDISPOSITION; IMMUNOCYTOCHEMISTRY; MOTONEURON; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; SYNAPTIC TRANSMISSION;

EID: 0032402093     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-23-09673.1998     Document Type: Article

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