메뉴 건너뛰기




Volumn 61, Issue 11 SUPPL. 6, 2003, Pages

Industry forum: Progress in pursuit of therapeutic A2A antagonists - The adenosine A2A receptor selective antagonist KW6002: Research and development toward a novel nondopaminergic therapy for Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2A RECEPTOR ANTAGONIST; DOPAMINE 2 RECEPTOR; ISTRADEFYLLINE; LEVODOPA; 4 AMINOBUTYRIC ACID; ADENOSINE A2A RECEPTOR; ANTIPARKINSON AGENT; OXIDOPAMINE; PURINE DERIVATIVE;

EID: 0344738697     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000095219.22086.31     Document Type: Review
Times cited : (98)

References (31)
  • 1
    • 0035404473 scopus 로고    scopus 로고
    • 2A receptor in basal ganglia
    • 2A receptor in basal ganglia. Biosci Biotechnol Biochem 2001;65:1447-1457.
    • (2001) Biosci Biotechnol Biochem , vol.65 , pp. 1447-1457
    • Kase, H.1
  • 6
    • 0030611334 scopus 로고    scopus 로고
    • 2A receptor antagonists as new agents for the treatment of Parkinson's disease
    • 2A receptor antagonists as new agents for the treatment of Parkinson's disease. Trends Pharmacol Sci 1997;18:338-344.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 338-344
    • Richardson, P.J.1    Kase, H.2    Jenner, P.G.3
  • 9
    • 0037145713 scopus 로고    scopus 로고
    • 2A receptor antagonist KW-6002 and its effect on gene expression in the rat brain
    • 2A receptor antagonist KW-6002 and its effect on gene expression in the rat brain. Brain Res 2002;953:119-125.
    • (2002) Brain Res , vol.953 , pp. 119-125
    • Aoyama, S.1    Koga, K.2    Mori, A.3
  • 11
    • 0026326607 scopus 로고
    • 2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: An in situ hybridization histochemistry study
    • 2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: an in situ hybridization histochemistry study. J Neurochem 1991;57:1062-1067.
    • (1991) J Neurochem , vol.57 , pp. 1062-1067
    • Schiffmann, S.N.1    Jacobs, O.2    Vanderhaegen, J.J.3
  • 13
    • 0034711582 scopus 로고    scopus 로고
    • 2A receptor antagonists KF17837 and KW-6002 potentiate rotation induced by dopaminergic drugs in hemi-parkinsonian rats
    • 2A receptor antagonists KF17837 and KW-6002 potentiate rotation induced by dopaminergic drugs in hemi-parkinsonian rats. Eur J Pharmacol 2000;408:249-255.
    • (2000) Eur J Pharmacol , vol.408 , pp. 249-255
    • Koga, K.1    Kurokawa, M.2    Ochi, M.3    Nakamura, J.4    Kuwana, Y.5
  • 14
    • 0031594271 scopus 로고    scopus 로고
    • 2A antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys
    • 2A antagonist: a novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys. Ann Neurol 1998;43:507-513.
    • (1998) Ann Neurol , vol.43 , pp. 507-513
    • Kanda, T.1    Jackson, M.J.2    Smith, L.A.3
  • 15
    • 0034049544 scopus 로고    scopus 로고
    • 2 dopamine agonists increases antiparkisonian activity but not dyskinesia in MPTP-treated monkeys
    • 2 dopamine agonists increases antiparkisonian activity but not dyskinesia in MPTP-treated monkeys. Exp Neurol 2000;162:321-327.
    • (2000) Exp Neurol , vol.162 , pp. 321-327
    • Kanda, T.1    Jackson, M.J.2    Smith, L.A.3
  • 17
    • 0029670648 scopus 로고    scopus 로고
    • 2A receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons
    • 2A receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons. J Neurosci 1996;16:605-611.
    • (1996) J Neurosci , vol.16 , pp. 605-611
    • Mori, A.1    Shindou, T.2    Ichimura, M.3    Nonaka, H.4    Kase, H.5
  • 20
    • 0034618819 scopus 로고    scopus 로고
    • 2A receptor antagonist decreases GABA release from rat globus pallidus increased by nigrostriatal lesions: A microdialysis study
    • 2A receptor antagonist decreases GABA release from rat globus pallidus increased by nigrostriatal lesions: a microdialysis study. Neuroscience 2000;100:53-62.
    • (2000) Neuroscience , vol.100 , pp. 53-62
    • Ochi, M.1    Koga, K.2    Kurokawa, M.3    Kase, H.4    Nakamura, J.5    Kuwana, Y.6
  • 21
    • 85087238655 scopus 로고    scopus 로고
    • 2A antagonists for a novel therapy in Parkinson's disease
    • 2A antagonists for a novel therapy in Parkinson's disease. Neurology 2002;(suppl):S44-S48.
    • (2002) Neurology , Issue.SUPPL.
    • Mori, A.1    Shindou, T.2
  • 22
    • 0025298139 scopus 로고
    • Primate model of movement disorders of basal ganglia origin
    • DeLong MR. Primate model of movement disorders of basal ganglia origin. Trends Neurosci 1990;13:281-285.
    • (1990) Trends Neurosci , vol.13 , pp. 281-285
    • DeLong, M.R.1
  • 23
    • 0033724826 scopus 로고    scopus 로고
    • Pathophysiology of the basal ganglia in Parkinson's disease
    • Obeso JA, Rodriguez-Oroz MC, Rodriguez M, et al. Pathophysiology of the basal ganglia in Parkinson's disease. Trends Neurosci 2000;23(suppl):S8-S19.
    • (2000) Trends Neurosci , vol.23 , Issue.SUPPL.
    • Obeso, J.A.1    Rodriguez-Oroz, M.C.2    Rodriguez, M.3
  • 26
    • 0025572196 scopus 로고
    • 2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons
    • 2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science 1990;250:1429-1432.
    • (1990) Science , vol.250 , pp. 1429-1432
    • Gerfen, C.R.1    Engber, T.M.2    Mahan, L.C.3
  • 29
    • 25544453322 scopus 로고    scopus 로고
    • A novel adenosine antagonist (KW-6002) as a treatment for advanced Parkinson's disease (PD) with motor complications
    • Abstract
    • Hubble J, Hauser J, Kyowa 6002-US-001 Study Group. A novel adenosine antagonist (KW-6002) as a treatment for advanced Parkinson's disease (PD) with motor complications. Neurology 2002;54(suppl 6):S21. Abstract.
    • (2002) Neurology , vol.54 , Issue.SUPPL. 6
    • Hubble, J.1    Hauser, J.2
  • 31


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.