-
1
-
-
1242316984
-
Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src: Implications for a role of lipid microdomains
-
Hur EM, Park YS, Lee BD, Jang IH, Kim HS, Kim TD, et al. Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src: Implications for a role of lipid microdomains. J Biol Chem 2004; 279: 5852-5860.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5852-5860
-
-
Hur, E.M.1
Park, Y.S.2
Lee, B.D.3
Jang, I.H.4
Kim, H.S.5
Kim, T.D.6
-
2
-
-
0035903145
-
β-Migrating very low density lipoprotein (beta VLDL) activates smooth muscle cell mitogen-activated protein (MAP) kinase via G protein-coupled receptor-mediated transactivation of the epidermal growth factor (EGF) receptor: Effect of MAP kinase activation on β VLDL plus EGF-induced cell proliferation
-
Zhao D, Letterman J, Schreiber BM. β-Migrating very low density lipoprotein (beta VLDL) activates smooth muscle cell mitogen-activated protein (MAP) kinase via G protein-coupled receptor-mediated transactivation of the epidermal growth factor (EGF) receptor: effect of MAP kinase activation on β VLDL plus EGF-induced cell proliferation. J Biol Chem 2001; 276: 30579-30588.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30579-30588
-
-
Zhao, D.1
Letterman, J.2
Schreiber, B.M.3
-
3
-
-
0035920246
-
G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells
-
Grewal JS, Luttrell LM, Raymond JR. G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells. J Biol Chem 2001; 276: 27335-27344.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27335-27344
-
-
Grewal, J.S.1
Luttrell, L.M.2
Raymond, J.R.3
-
4
-
-
0021336733
-
C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity
-
Cochet C, Gill GN, Meisenhelder J, Cooper JA, Hunter T. C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. J Biol Chem 1984; 259: 2553-2558.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 2553-2558
-
-
Cochet, C.1
Gill, G.N.2
Meisenhelder, J.3
Cooper, J.A.4
Hunter, T.5
-
5
-
-
0034681203
-
EGF receptor transactivation mediated by the proteolytic production of EGF-like agonists
-
Jan 18
-
Carpenter G. EGF receptor transactivation mediated by the proteolytic production of EGF-like agonists. Sci STKE 2000 Jan 18;2000(15):PE1.
-
(2000)
Sci STKE 2000
, Issue.15
-
-
Carpenter, G.1
-
6
-
-
0043172403
-
Transactivation joins multiple tracks to the ERK/MAPK cascade
-
Wetzker R, Bohmer FD. Transactivation joins multiple tracks to the ERK/MAPK cascade. Nat Rev Mol Cell Biol 2003; 4: 651-657.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 651-657
-
-
Wetzker, R.1
Bohmer, F.D.2
-
7
-
-
0036006453
-
Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
-
Pai R, Soreghan B, Szabo IL, Pavelka M, Baatar D, Tarnawski AS. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat Med 2002; 8: 289-293.
-
(2002)
Nat. Med.
, vol.8
, pp. 289-293
-
-
Pai, R.1
Soreghan, B.2
Szabo, I.L.3
Pavelka, M.4
Baatar, D.5
Tarnawski, A.S.6
-
8
-
-
0036152858
-
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
-
Asakura M, Kitakaze M, Takashima S, Liao Y, Ishikura F, Yoshinaka T, et al. Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nat Med 2002; 8: 35-40.
-
(2002)
Nat. Med.
, vol.8
, pp. 35-40
-
-
Asakura, M.1
Kitakaze, M.2
Takashima, S.3
Liao, Y.4
Ishikura, F.5
Yoshinaka, T.6
-
9
-
-
0034636685
-
Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors
-
/40/re1
-
Gutkind JS. Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors. Science STKE 2000/40/re1.
-
(2000)
Science STKE
-
-
Gutkind, J.S.1
-
10
-
-
0032938716
-
Regulation of tyrosine kinase cascades by G-protein-coupled receptors
-
Luttrell LM, Daaka Y, Lefkowitz RJ. Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr Opin Cell Biol 1999; 11: 177-183.
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 177-183
-
-
Luttrell, L.M.1
Daaka, Y.2
Lefkowitz, R.J.3
-
11
-
-
0029074408
-
Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells
-
Linseman DA, Benjamin CW, Jones DA. Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells. J Biol Chem 1995; 270: 12563-12568.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12563-12568
-
-
Linseman, D.A.1
Benjamin, C.W.2
Jones, D.A.3
-
12
-
-
0030044360
-
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
-
Daub H, Weiss FU, Wallasch C, Ullrich A. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996; 379: 557-560.
-
(1996)
Nature
, vol.379
, pp. 557-560
-
-
Daub, H.1
Weiss, F.U.2
Wallasch, C.3
Ullrich, A.4
-
14
-
-
0030683639
-
Signal characteristics of G protein-transactivated EGF receptor
-
Daub H, Wallasch C, Lankenau A, Herrlich A, Ullrich A. Signal characteristics of G protein-transactivated EGF receptor. EMBO J 1997; 16: 7032-7044.
-
(1997)
EMBO J.
, vol.16
, pp. 7032-7044
-
-
Daub, H.1
Wallasch, C.2
Lankenau, A.3
Herrlich, A.4
Ullrich, A.5
-
15
-
-
0032486476
-
Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway
-
Cunnick JM, Dorsey JF, Standley T, Turkson J, Kraker AJ, Fry DW, et al. Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway. J Biol Chem 1998; 273: 14468-14475.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14468-14475
-
-
Cunnick, J.M.1
Dorsey, J.F.2
Standley, T.3
Turkson, J.4
Kraker, A.J.5
Fry, D.W.6
-
16
-
-
0037470136
-
Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase C E
-
Piiper A, Elez R, You SJ, Kronenberger B, Loitsch S, Roche S, et al. Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase C E. J Biol Chem 2003; 278: 7065-7072.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7065-7072
-
-
Piiper, A.1
Elez, R.2
You, S.J.3
Kronenberger, B.4
Loitsch, S.5
Roche, S.6
-
17
-
-
0030837027
-
The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity
-
Tsai W, Morielli AD, Peralta EG. The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity. EMBO J 1997; 16: 4597-4605.
-
(1997)
EMBO J.
, vol.6
, pp. 4597-4605
-
-
Tsai, W.1
Morielli, A.D.2
Peralta, E.G.3
-
18
-
-
0033599039
-
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
-
Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C, et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 1999; 402: 884-888.
-
(1999)
Nature
, vol.402
, pp. 884-888
-
-
Prenzel, N.1
Zwick, E.2
Daub, H.3
Leserer, M.4
Abraham, R.5
Wallasch, C.6
-
19
-
-
0032934334
-
Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor
-
Miyazaki Y, Shinomura Y, Tsutsui S, Zushi S, Higashimoto Y, Kanayama S, et al. Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor. Gastroenterology 1999; 116: 78-89.
-
(1999)
Gastroenterology
, vol.116
, pp. 78-89
-
-
Miyazaki, Y.1
Shinomura, Y.2
Tsutsui, S.3
Zushi, S.4
Higashimoto, Y.5
Kanayama, S.6
-
20
-
-
0032555202
-
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells
-
Herrlich A, Daub H, Knebel A, Herrlich P, Ullrich A, Schultz G, et al. Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells. Proc Natl Acad Sci USA 1998; 95: 8985-8990.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8985-8990
-
-
Herrlich, A.1
Daub, H.2
Knebel, A.3
Herrlich, P.4
Ullrich, A.5
Schultz, G.6
-
21
-
-
0034650601
-
The platelet-derived-growth-factor receptor, not the epidermal-growth-factor receptor, is used by lysophosphatidic acid to activate p42/44 mitogen-activated protein kinase and to induce prostaglandin G/H synthase-2 in mesangial cells
-
Goppelt-Struebe M, Fickel S, Reiser CO. The platelet-derived-growth-factor receptor, not the epidermal-growth-factor receptor, is used by lysophosphatidic acid to activate p42/44 mitogen-activated protein kinase and to induce prostaglandin G/H synthase-2 in mesangial cells. Biochem J 2000; 345: 217-224.
-
(2000)
Biochem. J.
, vol.345
, pp. 217-224
-
-
Goppelt-Struebe, M.1
Fickel, S.2
Reiser, C.O.3
-
22
-
-
0034697092
-
Involvement of the platelet-derived growth factor receptor in angiotensin II-induced activation of extracellular regulated kinases 1 and 2 in human mesangial cells
-
Mondorf UF, Geiger H, Herrero M, Zeuzem S, Piiper A. Involvement of the platelet-derived growth factor receptor in angiotensin II-induced activation of extracellular regulated kinases 1 and 2 in human mesangial cells. FEBS Lett 2000; 472: 129-132.
-
(2000)
FEBS Lett.
, vol.472
, pp. 129-132
-
-
Mondorf, U.F.1
Geiger, H.2
Herrero, M.3
Zeuzem, S.4
Piiper, A.5
-
23
-
-
0034717056
-
Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc
-
Heeneman S, Haendeler J, Saito Y, Ishida M, Berk BC. Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc. J Biol Chem 2000; 275: 15926-15932.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15926-15932
-
-
Heeneman, S.1
Haendeler, J.2
Saito, Y.3
Ishida, M.4
Berk, B.C.5
-
24
-
-
0036831229
-
Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation
-
McMahon B, Mitchell D, Shattock R, Martin F, Brady HR, Godson C. Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation. FASEB J 2002; 16: 1817-1819.
-
(2002)
FASEB J.
, vol.16
, pp. 1817-1819
-
-
McMahon, B.1
Mitchell, D.2
Shattock, R.3
Martin, F.4
Brady, H.R.5
Godson, C.6
-
25
-
-
0037068833
-
D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission
-
Kotecha SA, Oak JN, Jackson MF, Perez Y, Orser BA, Van Tol HH, et al. D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission. Neuron 2002; 35: 1111-1122.
-
(2002)
Neuron
, vol.35
, pp. 1111-1122
-
-
Kotecha, S.A.1
Oak, J.N.2
Jackson, M.F.3
Perez, Y.4
Orser, B.A.5
Van Tol, H.H.6
-
26
-
-
0037364416
-
Receptor tyrosine kinase transactivation: Fine-tuning synaptic transmission
-
Ferguson SS. Receptor tyrosine kinase transactivation: fine-tuning synaptic transmission. Trends Neurosci 2003; 26: 119-122.
-
(2003)
Trends Neurosci.
, vol.26
, pp. 119-122
-
-
Ferguson, S.S.1
-
27
-
-
0028805435
-
Thrombin stimulates phosphorylation of insulin-like growth factor-1 receptor, insulin receptor substrate-1, and phospholipase C-γ I in rat aortic smooth muscle cells
-
Rao GN, Delafontaine P, Runge MS. Thrombin stimulates phosphorylation of insulin-like growth factor-1 receptor, insulin receptor substrate-1, and phospholipase C-γ I in rat aortic smooth muscle cells. J Biol Chem 1995; 270: 27871-27875.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27871-27875
-
-
Rao, G.N.1
Delafontaine, P.2
Runge, M.S.3
-
28
-
-
0036895875
-
The fibroblast growth factor receptor is at the site of convergence between μ-opioid receptor and growth factor signaling pathways in rat C6 glioma cells
-
Belcheva MM, Haas PD, Tan Y, Heaton VM, Coscia CJ. The fibroblast growth factor receptor is at the site of convergence between μ-opioid receptor and growth factor signaling pathways in rat C6 glioma cells. J Pharmacol Exp Ther 2002; 303: 909-918.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.303
, pp. 909-918
-
-
Belcheva, M.M.1
Haas, P.D.2
Tan, Y.3
Heaton, V.M.4
Coscia, C.J.5
-
29
-
-
0035853065
-
Activation of Trk neurotrophin receptors in the absence of neurotrophins
-
Lee FS, Chao MV. Activation of Trk neurotrophin receptors in the absence of neurotrophins. Proc Natl Acad Sci USA 2001; 98: 3555-3560.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3555-3560
-
-
Lee, F.S.1
Chao, M.V.2
-
30
-
-
0042916422
-
Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors
-
Pai R, Nakamura T, Moon WS, Tarnawski AS. Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors. FASEB J 2003; 17: 1640-1647.
-
(2003)
FASEB J.
, vol.17
, pp. 1640-1647
-
-
Pai, R.1
Nakamura, T.2
Moon, W.S.3
Tarnawski, A.S.4
-
31
-
-
0032502765
-
Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells
-
Eguchi S, Numaguchi K, Iwasaki H, Matsumoto T, Yamakawa T, Utsunomiya H, et al. Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. J Biol Chem 1998; 273: 8890-8896.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8890-8896
-
-
Eguchi, S.1
Numaguchi, K.2
Iwasaki, H.3
Matsumoto, T.4
Yamakawa, T.5
Utsunomiya, H.6
-
32
-
-
0038581051
-
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
-
Gschwind A, Hart S, Fischer OM, Ullrich A. TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO J 2003; 22: 2411-2421.
-
(2003)
EMBO J.
, vol.22
, pp. 2411-2421
-
-
Gschwind, A.1
Hart, S.2
Fischer, O.M.3
Ullrich, A.4
-
33
-
-
0037157854
-
The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors
-
Yan Y, Shirakabe K, Werb Z. The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors. J Cell Biol 2002; 158: 221-226.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 221-226
-
-
Yan, Y.1
Shirakabe, K.2
Werb, Z.3
-
34
-
-
0344443646
-
Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone
-
Roelle S, Grosse R, Aigner A, Krell HW, Czubayko F, Gudermann T. Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone. J Biol Chem 2003; 278: 47307-47318.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 47307-47318
-
-
Roelle, S.1
Grosse, R.2
Aigner, A.3
Krell, H.W.4
Czubayko, F.5
Gudermann, T.6
-
35
-
-
1342322686
-
Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion
-
Schäfer B, Gschwind A, Ullrich A. Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion. Oncogene 2004; 23: 991-999.
-
(2004)
Oncogene
, vol.23
, pp. 991-999
-
-
Schäfer, B.1
Gschwind, A.2
Ullrich, A.3
-
36
-
-
0030770603
-
Critical role of calcium-dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling
-
Zwick E, Daub H, Aoki N, Yamaguchi-Aoki Y, Tinhofer I, Maly K, et al. Critical role of calcium-dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling. J Biol Chem 1997; 272: 24767-24770.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24767-24770
-
-
Zwick, E.1
Daub, H.2
Aoki, N.3
Yamaguchi-Aoki, Y.4
Tinhofer, I.5
Maly, K.6
-
37
-
-
0032577953
-
Angiotensin II type 1 receptor-induced extracellular signal-regulated protein kinase activation is mediated by Ca2+/calmodulin-dependent transactivation of epidermal growth factor receptor
-
Murasawa S, Mori Y, Nozawa Y, Gotoh N, Shibuya M, Masaki H, et al. Angiotensin II type 1 receptor-induced extracellular signal-regulated protein kinase activation is mediated by Ca2+/calmodulin-dependent transactivation of epidermal growth factor receptor. Circ Res 1998; 82: 1338-1348.
-
(1998)
Circ. Res.
, vol.82
, pp. 1338-1348
-
-
Murasawa, S.1
Mori, Y.2
Nozawa, Y.3
Gotoh, N.4
Shibuya, M.5
Masaki, H.6
-
38
-
-
0034697127
-
Distinct effects of N-acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca(2+) levels
-
Wang D, Yu X, Cohen RA, Brecher P. Distinct effects of N-acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca(2+) levels. J Biol Chem 2000; 275: 12223-12230.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12223-12230
-
-
Wang, D.1
Yu, X.2
Cohen, R.A.3
Brecher, P.4
-
39
-
-
0035827528
-
Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGF-R) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade
-
Andreev J, Galisteo ML, Kranenburg O, Logan SK, Chiu ES, Okigaki M, et al. Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGF-R) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade. J Biol Chem 2001; 276: 20130-20135.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20130-20135
-
-
Andreev, J.1
Galisteo, M.L.2
Kranenburg, O.3
Logan, S.K.4
Chiu, E.S.5
Okigaki, M.6
-
40
-
-
0038061562
-
A central role of EGF receptor transactivation in angiotensin II-induced cardiac hypertrophy
-
Shah BH, Catt KJ. A central role of EGF receptor transactivation in angiotensin II-induced cardiac hypertrophy. Trends Pharmacol Sci 2003; 24: 239-244.
-
(2003)
Trends Pharmacol. Sci.
, vol.24
, pp. 239-244
-
-
Shah, B.H.1
Catt, K.J.2
-
41
-
-
0035933814
-
Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: A co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding
-
Pierce KL, Tohgo A, Ahn S, Field ME, Luttrell LM, Lefkowitz RJ. Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding. J Biol Chem 2001; 276: 23155-23160.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23155-23160
-
-
Pierce, K.L.1
Tohgo, A.2
Ahn, S.3
Field, M.E.4
Luttrell, L.M.5
Lefkowitz, R.J.6
-
42
-
-
0034737483
-
The β(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
-
Maudsley S, Pierce KL, Zamah AM, Miller WE, Ahn S, Daaka Y, et al. The β(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J Biol Chem 2000; 275: 9572-9580.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9572-9580
-
-
Maudsley, S.1
Pierce, K.L.2
Zamah, A.M.3
Miller, W.E.4
Ahn, S.5
Daaka, Y.6
-
43
-
-
1342304124
-
Gs Protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: Implications for epithelial secretory responses
-
Bertelsen LS, Barrett KE, Keely SJ. Gs Protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: Implications for epithelial secretory responses. J Biol Chem 2004; 279: 6271-6279.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 6271-6279
-
-
Bertelsen, L.S.1
Barrett, K.E.2
Keely, S.J.3
-
44
-
-
0030614911
-
Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
-
Luttrell LM, Della Rocca GJ, van Biesen T, Luttrell DK, Lefkowitz RJ. Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. J Biol Chem 1997; 272: 4637-4644.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4637-4644
-
-
Luttrell, L.M.1
Della Rocca, G.J.2
van Biesen, T.3
Luttrell, D.K.4
Lefkowitz, R.J.5
-
45
-
-
0030613761
-
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
-
Daaka Y, Luttrell LM, Lefkowitz RJ. Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A. Nature 1997; 390: 88-91.
-
(1997)
Nature
, vol.390
, pp. 88-91
-
-
Daaka, Y.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
46
-
-
0346037347
-
Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells
-
Piiper A, Dikic I, Lutz MP, Leser J, Kronenberger B, Elez R, et al. Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells. J Biol Chem 2002; 277: 43623-30.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43623-43630
-
-
Piiper, A.1
Dikic, I.2
Lutz, M.P.3
Leser, J.4
Kronenberger, B.5
Elez, R.6
-
47
-
-
0033776193
-
PDGF-C is a new protease-activated ligand for the PDGFα-receptor
-
Li X, Ponten A, Aase K, Karlsson L, Abramsson A, Uutela M, et al. PDGF-C is a new protease-activated ligand for the PDGFα-receptor. Nat Cell Biol 2000; 2: 302-309.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 302-309
-
-
Li, X.1
Ponten, A.2
Aase, K.3
Karlsson, L.4
Abramsson, A.5
Uutela, M.6
-
48
-
-
0035003785
-
PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor
-
Bergsten E, Uutela M, Li X, Pietras K, Ostman A, Heldin CH, et al. PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor. Nat Cell Biol 2001; 3: 512-516.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 512-516
-
-
Bergsten, E.1
Uutela, M.2
Li, X.3
Pietras, K.4
Ostman, A.5
Heldin, C.H.6
-
49
-
-
0033583220
-
c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function
-
Biscardi JS, Maa MC, Tice DA, Cox ME, Leu TH, Parsons SJ. c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J Biol Chem 1999; 274: 8335-8343.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8335-8343
-
-
Biscardi, J.S.1
Maa, M.C.2
Tice, D.A.3
Cox, M.E.4
Leu, T.H.5
Parsons, S.J.6
-
50
-
-
0029860936
-
Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
-
Rosette C, Karin M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 1996; 274: 1194-1197.
-
(1996)
Science
, vol.274
, pp. 1194-1197
-
-
Rosette, C.1
Karin, M.2
-
51
-
-
15144343374
-
Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation
-
Bae YS, Kang SW, Seo MS, Baines IC, Tekle E, Chock PB, et al. Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation. J Biol Chem 1997; 272: 217-221.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 217-221
-
-
Bae, Y.S.1
Kang, S.W.2
Seo, M.S.3
Baines, I.C.4
Tekle, E.5
Chock, P.B.6
-
52
-
-
0034815331
-
N-acetylcysteine inhibits angiotensin II-mediated activation of extracellular signal-regulated kinase and epidermal growth factor receptor
-
Frank GD, Eguchi S, Inagami T, Motley ED. N-acetylcysteine inhibits angiotensin II-mediated activation of extracellular signal-regulated kinase and epidermal growth factor receptor. Biochem Biophys Res Commun 2001; 280: 1116-1119.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 1116-1119
-
-
Frank, G.D.1
Eguchi, S.2
Inagami, T.3
Motley, E.D.4
-
53
-
-
0034724860
-
Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca(2+), PYK-2, and p60(src)
-
Keely SJ, Calandrella SO, Barrett KE. Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca(2+), PYK-2, and p60(src). J Biol Chem 2000; 275: 12619-12625.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12619-12625
-
-
Keely, S.J.1
Calandrella, S.O.2
Barrett, K.E.3
-
54
-
-
0036153719
-
Calcium-independent activation of extracellularly regulated kinases 1 and 2 in hepatic C9 cells: Roles of PKCδ, Src /proline-rich tyrosine kinase 2, and epidermal growth factor receptor transactivation
-
Shah BH, Catt KJ Calcium-independent activation of extracellularly regulated kinases 1 and 2 in hepatic C9 cells: Roles of PKCδ, Src/proline-rich tyrosine kinase 2, and epidermal growth factor receptor transactivation. Mol Pharmacol 2002; 61: 343-351.
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 343-351
-
-
Shah, B.H.1
Catt, K.J.2
-
55
-
-
0030032998
-
Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels
-
Rosen LB, Greenberg ME. Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. Proc Natl Acad Sci USA 1996; 93: 1113-1118.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1113-1118
-
-
Rosen, L.B.1
Greenberg, M.E.2
-
56
-
-
0037205044
-
Signaling pathways for PC12 cell differentiation: Making the right connections
-
Vaudry D, Stork PJ, Lazarovici P, Eiden LE. Signaling pathways for PC12 cell differentiation: making the right connections. Science 2002; 296: 1648-1649.
-
(2002)
Science
, vol.296
, pp. 1648-1649
-
-
Vaudry, D.1
Stork, P.J.2
Lazarovici, P.3
Eiden, L.E.4
-
57
-
-
0034952792
-
Nerve growth factor stimulation of p42/p44 mitogen-activated protein kinase in PC12 cells: Role of G(i/o), G protein-coupled receptor kinase 2, β-arrestin I, and endocytic processing
-
Rakhit S, Pyne S, Pyne NJ. Nerve growth factor stimulation of p42/p44 mitogen-activated protein kinase in PC12 cells: role of G(i/o), G protein-coupled receptor kinase 2, β-arrestin I, and endocytic processing. Mol Pharmacol 2001; 60: 63-70.
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 63-70
-
-
Rakhit, S.1
Pyne, S.2
Pyne, N.J.3
-
58
-
-
0035958899
-
Tethering of the platelet-derived growth factor β receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells
-
Alderton F, Rakhit S, Kong KC, Palmer T, Sambi B, Pyne S, Pyne NJ. Tethering of the platelet-derived growth factor β receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells. J Biol Chem 2001; 276: 28578-28585.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28578-28585
-
-
Alderton, F.1
Rakhit, S.2
Kong, K.C.3
Palmer, T.4
Sambi, B.5
Pyne, S.6
Pyne, N.J.7
-
59
-
-
0038660687
-
Phosphorylation of tyrosine 319 of the angiotensin II type 1 receptor mediates angiotensin II-induced trans-activation of the epidermal growth factor receptor
-
Seta K, Sadoshima J. Phosphorylation of tyrosine 319 of the angiotensin II type 1 receptor mediates angiotensin II-induced trans-activation of the epidermal growth factor receptor. J Biol Chem 2003; 278: 9019-9026.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9019-9026
-
-
Seta, K.1
Sadoshima, J.2
-
60
-
-
0037088607
-
Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides
-
Lee FS, Rajagopal R, Kim AH, Chang PC, Chao MV. Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides. J Biol Chem 2002; 277: 9096-9102.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9096-9102
-
-
Lee, F.S.1
Rajagopal, R.2
Kim, A.H.3
Chang, P.C.4
Chao, M.V.5
-
61
-
-
0036006816
-
Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors
-
Lee FS, Rajagopal R, Chao MV. Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors. Cytokine Growth Factor Rev 2002; 13: 11-17.
-
(2002)
Cytokine Growth Factor Rev.
, vol.13
, pp. 11-17
-
-
Lee, F.S.1
Rajagopal, R.2
Chao, M.V.3
-
62
-
-
0032079960
-
Angiotensin II stimulates ERK via two pathways in epithelial cells: Protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway
-
Li X, Lee JW, Graves LM, Earp HS. Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway. EMBO J 1998; 17: 2574-2583.
-
(1998)
EMBO J.
, vol.17
, pp. 2574-2583
-
-
Li, X.1
Lee, J.W.2
Graves, L.M.3
Earp, H.S.4
-
63
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, Hynes NE. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000; 19: 3159-3167.
-
(2000)
EMBO J.
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
-
64
-
-
0037145061
-
Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
-
Schlessinger J. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 2002; 110: 669-672.
-
(2002)
Cell
, vol.110
, pp. 669-672
-
-
Schlessinger, J.1
-
65
-
-
0037429737
-
Epidermal growth factor receptor: Mechanisms of activation and signaling
-
Jorissen RN Walker F, Pouliot N, Garrett TP, Ward CW, Burgess AW. Epidermal growth factor receptor: mechanisms of activation and signaling. Exp Cell Res 2003; 284: 31-53.
-
(2003)
Exp. Cell Res.
, vol.284
, pp. 31-53
-
-
Jorissen, R.N.1
Walker, F.2
Pouliot, N.3
Garrett, T.P.4
Ward, C.W.5
Burgess, A.W.6
-
66
-
-
0036828287
-
Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation
-
Gschwind A, Prenzel N, Ullrich A. Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation. Cancer Res 2002; 62: 6329-6336.
-
(2002)
Cancer Res.
, vol.62
, pp. 6329-6336
-
-
Gschwind, A.1
Prenzel, N.2
Ullrich, A.3
-
67
-
-
0032808149
-
Bradykinin B(2) receptor-mediated mitogen-activated protein kinase activation in COS-7 cells requires dual signaling via both protein kinase C pathway and epidermal growth factor receptor transactivation
-
Adomeit A, Graness A, Gross S, Seedorf K, Wetzker R, Liebmann C. Bradykinin B(2) receptor-mediated mitogen-activated protein kinase activation in COS-7 cells requires dual signaling via both protein kinase C pathway and epidermal growth factor receptor transactivation. Mol Cell Biol 1999; 19: 5289-5297.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 5289-5297
-
-
Adomeit, A.1
Graness, A.2
Gross, S.3
Seedorf, K.4
Wetzker, R.5
Liebmann, C.6
-
68
-
-
0346725911
-
Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor
-
Rubio I, Rennert K, Wittig U, Wetzker R. Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor. Biochem J 2003; 376: 571-576.
-
(2003)
Biochem. J.
, vol.376
, pp. 571-576
-
-
Rubio, I.1
Rennert, K.2
Wittig, U.3
Wetzker, R.4
-
69
-
-
0032730852
-
An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid
-
Laffargue M, Raynal P, Yart A, Peres C, Wetzker R, Roche S, et al. An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid. J Biol Chem 1999; 274: 32835-32841.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32835-32841
-
-
Laffargue, M.1
Raynal, P.2
Yart, A.3
Peres, C.4
Wetzker, R.5
Roche, S.6
-
70
-
-
0344875505
-
Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor
-
Nair VD, Sealfon SC. Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor. J Biol Chem 2003; 278: 47053-47061.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 47053-47061
-
-
Nair, V.D.1
Sealfon, S.C.2
-
71
-
-
0033601182
-
Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt
-
Eguchi S, Iwasaki H, Ueno H, Frank GD, Motely ED, Eguchi K, et al. Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt. J Biol Chem 1999; 274: 36843-36851.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36843-36851
-
-
Eguchi, S.1
Iwasaki, H.2
Ueno, H.3
Frank, G.D.4
Motely, E.D.5
Eguchi, K.6
-
72
-
-
0032875460
-
Mechanism of action and in vivo role of platelet-derived growth factor
-
Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 1999; 79: 1283-1316.
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1283-1316
-
-
Heldin, C.H.1
Westermark, B.2
-
73
-
-
0035976138
-
Signaling by fibroblast growth factors: The inside story
-
Goldfarb M. Signaling by fibroblast growth factors: the inside story. Science STKE 2001; PE37.
-
(2001)
Science STKE
-
-
Goldfarb, M.1
-
74
-
-
0041488911
-
Trk receptors: Roles in neuronal signal transduction
-
Huang EJ, Reichardt LF. Trk receptors: roles in neuronal signal transduction. Ann Rev Biochem 2003; 72: 609-642.
-
(2003)
Ann. Rev. Biochem.
, vol.72
, pp. 609-642
-
-
Huang, E.J.1
Reichardt, L.F.2
-
75
-
-
0037458957
-
Protein kinase A mediates cAMP-induced tyrosine phosphorylation of the epidermal growth factor receptor
-
Piiper A, Lutz MP, Cramer H, Elez R, Kronenberger B, Dikic I, et al. Protein kinase A mediates cAMP-induced tyrosine phosphorylation of the epidermal growth factor receptor. Biochem Biophys Res Commun 2003; 301: 848-854.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.301
, pp. 848-854
-
-
Piiper, A.1
Lutz, M.P.2
Cramer, H.3
Elez, R.4
Kronenberger, B.5
Dikic, I.6
-
76
-
-
0345601083
-
Met, metastasis, motility and more
-
Birchmeier C, Birchmeier W, Gherardi E, Vande Wounde GF. Met, metastasis, motility and more. Nat Rev Mol Cell Biol 2003; 4: 915-925.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
Birchmeier, W.2
Gherardi, E.3
Vande Wounde, G.F.4
-
77
-
-
0036372960
-
Receptor tyrosine kinases as target for anti-cancer therapy
-
Brunelleschi S, Penengo L, Santoro MM, Gaudino G. Receptor tyrosine kinases as target for anti-cancer therapy. Curr Pharm Design 2002; 8(22): 1959-72.
-
(2002)
Curr. Pharm. Design
, vol.8
, Issue.22
, pp. 1959-1972
-
-
Brunelleschi, S.1
Penengo, L.2
Santoro, M.M.3
Gaudino, G.4
-
78
-
-
0036399117
-
Agents targeting ras signaling pathway
-
Dancey JE. Agents targeting ras signaling pathway. Curr Pharm Design 2002; 8(25): 2259-67.
-
(2002)
Curr. Pharm. Design
, vol.8
, Issue.25
, pp. 2259-2267
-
-
Dancey, J.E.1
-
79
-
-
0037279999
-
Small-molecule inhibitors of fibroblast growth factor receptor (FGFR) tyrosine kinases (TK)
-
Manetti F, Botta M. Small-molecule inhibitors of fibroblast growth factor receptor (FGFR) tyrosine kinases (TK). Curr Pharm Design 2003; 9(7): 567-81.
-
(2003)
Curr. Pharm. Design
, Issue.7
, pp. 567-581
-
-
Manetti, F.1
Botta, M.2
|