BDNF-induced recruitment of TrkB receptor into neuronal lipid rafts: Roles in synaptic modulation

Journal of Cell Biology

Volumn 167, Issue 6, 2004, Pages 1205-1215

  Suzuki, Shingo ^a,b,c   Numakawa, Tadahiro ^d   Shimazu, Kazuhiro ^f   Koshimizu, Hisatsugu ^a   Hara, Tomoko ^a   Hatanaka, Hiroshi ^b   Mei, Lin ^e   Lu, Bai ^f   Kojima, Masami ^a,c  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

^f EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CHOLESTEROL; LIGAND; PROTEIN TYROSINE KINASE; RECEPTOR BLOCKING AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL SURFACE; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; HIPPOCAMPUS; LIPID MEMBRANE; NERVE CELL MEMBRANE; NERVE CELL PLASTICITY; NEUROMODULATION; NEUROTRANSMITTER RELEASE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TETANUS;

ANIMALS; BETA-CYCLODEXTRINS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SURVIVAL; HUMANS; MEMBRANE MICRODOMAINS; NEURONS; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; RATS; RECEPTOR, NERVE GROWTH FACTOR; RECEPTOR, TRKB; RECEPTORS, NERVE GROWTH FACTOR; SYNAPTIC TRANSMISSION;

ANIMALIA;

EID: 11244275704     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200404106     Document Type: Article

References (42)

1. Anderson, R.G., and K. Jacobson. 2002. A role for lipid shells in targeting proteins to caveolae, rafts, and other lipid domains. Science. 296:1821-1825.
2. Bibel, M., and Y.A. Barde. 2000. Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev. 14:2919-2937.
3. Bilderback, T.R., V.R. Gazula, M.P. Lisanti, and R.T. Dobrowsky. 1999. Caveolin interacts with Trk A and p75 (NTR) and regulates neurotrophin signaling pathways. J. Biol. Chem. 274:257-263.
4. Binder, D.K., M.J. Routbort, and J.O. McNamara. 1999. Immunohistochemical evidence of seizure-induced activation of trk receptors in the mossy fiber pathway of adult rat hippocampus. J. Neurosci. 19:4616-4626.
5. Citores, L., J. Wesche, E. Kolpakova, and S. Olsnes. 1999. Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors. Mol. Biol. Cell. 10:3835-3848.
6. Fawcett, J.P., R. Aloyz, J.H. McLean, S. Pareek, F.D. Miller, P.S. McPherson, and R.A. Murphy. 1997. Detection of brain-derived neurotrophic factor in a vesicular fraction of brain synaptosomes. J. Biol. Chem. 272:8837-8840.
7. Figurov, A., L.D. Pozzo-Miller, P. Olafsson, T. Wang, and B. Lu. 1996. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. 381:706-709.
8. Ghosh, A., J. Carnahan, and M.E. Greenberg. 1994. Requirement for BDNF in activity-dependent survival of cortical neurons. Science. 263:1618-1623.
9. Glebov, O.O., and B.J. Nichols. 2004. Lipid raft proteins have a random distribution during localized activation of the T-cell receptor. Nat. Cell Biol. 6:238-243.
10. Gottschalk, W.A., L.D. Pozzo-Miller, A. Figurov, and B. Lu. 1998. Presynaptic modulation of synaptic transmission and plasticity by brain-derived neurotrophic factor in the developing hippocampus. J. Neurosci. 18:6830-6839.
11. Gottschalk, W.A., H. Jiang, N. Tartaglia, L. Feng, A. Figurov, and B. Lu. 1999. Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus. Learn. Mem. 6:243-256.
12. Guirland, C., S. Suzuki, M. Kojima, B. Lu, and J.Q. Zheng. 2004. Lipid rafts mediate chemotropic guidance of nerve growth cones. Neuron. 42:51-62.
13. Hartmann, M., R. Heumann, and V. Lessmann. 2001. Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. EMBO J. 20:5887-5897.
14. Henderson, L.P., L. Lin, A. Prasad, C.A. Paul, T.Y. Chang, and R.A. Maue. 2000. Embryonic striatal neurons from niemann-pick type C mice exhibit defects in cholesterol metabolism and neurotrophin responsiveness. J. Biol. Chem. 275:20179-20187.
15. Hering, H., C.C. Lin, and M. Sheng. 2003. Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J. Neurosci. 23:3262-3271.
16. Hempstead, B.L. 2002. The many faces of p75NTR. Curr. Opin. Neurobiol. 12:260-267.
17. Higuchi, H., T. Yamashita, H. Yoshikawa, and M. Tohyama. 2003. PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts. EMBO J. 22:1790-1800.
18. Huang, C.S., J. Zhou, A.K. Feng, C.C. Lynch, J. Klumperman, S.J. DeArmond, and W.C. Mobley. 1999. Nerve growth factor signaling in caveolae-like domains at the plasma membrane. J. Biol. Chem. 274:36707-36714.
19. Jovanovic, J.N., A.J. Czernik, A.A. Fienberg, P. Greengard, and T.S. Sihra. 2000. Synapsins as mediators of BDNF-enhanced neurotransmitter release. Nat. Neurosci. 3:323-329.
20. Kaplan, D.R., and F.D. Miller. 2000. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10:381-391.
21. Kawabuchi, M., Y. Satomi, T. Takao, Y. Shimonishi, S. Nada, K. Nagai, A. Tarakhovsky, and M. Okada. 2000. Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature. 404:999-1003.
22. Kojima, M., N. Takei, T. Numakawa, Y. Ishikawa, S. Suzuki, T. Matsumoto, R. Katoh-Semba, H. Nawa, and H. Hatanaka. 2001. Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neurites of cultured hippocampal neurons. J. Neurosci. Res. 64:1-10.
23. Lessmann, V. 1998. Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS. Gen. Pharmacol. 31:667-674.
24. Lu, B. 2003. BDNF and activity-dependent synaptic modulation. Learn. Mem. 10:86-98.
25. Ma, L., Y.Z. Huang, G.M. Pitcher, J.G. Valtschanoff, Y.H. Ma, L.Y. Feng, B. Lu, W.C. Xiong, M.W. Salter, R.J. Weinberg, and L. Mei. 2003. Ligand-dependent recruitment of the ErbB4 signaling complex into neuronal lipid rafts. J. Neurosci. 23:3164-3175.
26. Matsumoto, T., T. Numakawa, N. Adachi, D. Yokomaku, S. Yamagishi, N. Takei, and H. Hatanaka. 2001. Brain-derived neurotrophic factor enhances depolarization-evoked glutamate release in cultured cortical neurons. J. Neurochem. 79:522-530.
27. McAllister, A.K., D.C. Lo, and L.C. Katz. 1995. Neurotrophins regulate dendritic growth in developing visual cortex. Neuron. 15:791-803.
28. Mineo, C., G.N. Gill, and R.G. Anderson. 1999. Regulated migration of epidermal growth factor receptor from caveolae. J. Biol. Chem. 274:30636-30643.
29. Munro, S. 2003. Lipid rafts: elusive or illusive? Cell. 115:377-388.
30. Murphy, D.D., and M. Segal. 1996. Regulation of dendritic spine density in cultured rat hippocampal neurons by steroid hormones. J. Neurosci. 16:4059-4068.
31. Numakawa, T., D. Yokomaku, K. Kiyosue, N. Adachi, T. Matsumoto, Y. Numakawa, T. Taguchi, H. Hatanaka, and M. Yamada. 2002. Basic fibroblast growth factor evokes a rapid glutamate release through activation of the MAPK pathway in cultured cortical neurons. J. Biol. Chem. 277:28861-28869.
32. Paratcha, G., and C.F. Ibanez. 2002. Lipid rafts and the control of neurotrophic factor signaling in the nervous system: variations on a theme. Curr. Opin. Neurobiol. 12:542-549.
33. Paratcha, G., F. Ledda, L. Baars, M. Coulpier, V. Besset, J. Anders, R. Scott, and C.F. Ibanez. 2001. Released GFRalphal potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts. Neuron. 29:171-184.
34. Patterson, S.L., T. Abel, T.A. Deuel, K.C. Martin, J.C. Rose, and E.R. Kandel. 1996. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. 16:1137-1145.
35. Pike, L.J. 2003. Lipid rafts: bringing order to chaos. J. Lipid Res. 44:655-667.
36. Ryan, T.A., H. Reuter, B. Wendland, F.E. Schweizer, R.W. Tsien, and S.J. Smith. 1993. The kinetics of synaptic vesicle recycling measured at single presynaptic boutons. Neuron. 11:713-724.
37. Schuck, S., M. Honsho, K. Ekroos, A. Shevchenko, and K. Simons. 2003. Resistance of cell membranes to different detergents. Proc. Natl. Acad. Sci. USA. 100:5795-5800.
38. Simons, K., and D. Toomre. 2000. Lipid rafts and signal transduction. Nat. Rev. Mol. Cell Biol. 1:31-39.
39. Takei, N., T. Numakawa, S. Kozaki, N. Sakai, Y. Endo, M. Takahashi, and H. Hatanaka. 1998. Brain-derived neurotrophic factor induces rapid and transient release of glutamate through the non-exocytotic pathway from cortical neurons. J. Biol. Chem. 273:27620-27624.
40. Tansey, M.G., R.H. Baloh, J. Milbrandt, and E.M. Johnson Jr. 2000. GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival. Neuron. 25:611-623.
41. Thiele, C., M.J. Hannah, F. Fahrenholz, and W.B. Huttner. 2000. Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles. Nat. Cell Biol. 2:42-49.
42. Yamada, M., K. Tanabe, K. Wada, K. Shimoke, Y. Ishikawa, T. Ikeuchi, S. Koizumi, and H. Hatanaka. 2001. Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons. J. Neurochem. 78:940-951.