메뉴 건너뛰기




Volumn 28, Issue 1, 2006, Pages 51-62

The role of virus-induced regulatory T cells in immunopathology

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN SPECIFICITY; BACTERIAL INFECTION; CELL KILLING; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; HELPER CELL; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; IMMUNOPATHOLOGY; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; VIRUS IMMUNITY; VIRUS INDUCTION; VIRUS INFECTION;

EID: 33747590748     PISSN: 03444325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00281-006-0019-2     Document Type: Review
Times cited : (47)

References (148)
  • 1
    • 0014667395 scopus 로고
    • Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
    • Nishizuka Y, Sakakura T (1969) Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science 166:753-755
    • (1969) Science , vol.166 , pp. 753-755
    • Nishizuka, Y.1    Sakakura, T.2
  • 2
    • 0014792798 scopus 로고
    • Cell interactions in the induction of tolerance: The role of thymic lymphocytes
    • Gershon RK, Kondo K (1970) Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology 18:723-737
    • (1970) Immunology , vol.18 , pp. 723-737
    • Gershon, R.K.1    Kondo, K.2
  • 4
    • 0023038126 scopus 로고
    • Molecular analysis of the hotspot of recombination in the murine major histocompatibility complex
    • Kobori JA, Strauss E, Minard K, Hood L (1986) Molecular analysis of the hotspot of recombination in the murine major histocompatibility complex. Science 234:173-179
    • (1986) Science , vol.234 , pp. 173-179
    • Kobori, J.A.1    Strauss, E.2    Minard, K.3    Hood, L.4
  • 5
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (1995) Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155:1151-1164
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 7
    • 0034055570 scopus 로고    scopus 로고
    • Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift
    • Doetze A, Satoguina J, Burchard G, Rau T, Loliger C, Fleischer B, Hoerauf A (2000) Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift. Int Immunol 12:623-630
    • (2000) Int Immunol , vol.12 , pp. 623-630
    • Doetze, A.1    Satoguina, J.2    Burchard, G.3    Rau, T.4    Loliger, C.5    Fleischer, B.6    Hoerauf, A.7
  • 9
    • 0037086525 scopus 로고    scopus 로고
    • CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons
    • MacDonald AJ, Duffy M, Brady MT, McKiernan S, Hall W, Hegarty J, Curry M, Mills KH (2002) CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J Infect Dis 185:720-727
    • (2002) J Infect Dis , vol.185 , pp. 720-727
    • MacDonald, A.J.1    Duffy, M.2    Brady, M.T.3    McKiernan, S.4    Hall, W.5    Hegarty, J.6    Curry, M.7    Mills, K.H.8
  • 10
    • 1642305619 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions
    • Suvas S, Azkur AK, Kim BS, Kumaraguru U, Rouse BT (2004) CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions. J Immunol 172:4123-4132
    • (2004) J Immunol , vol.172 , pp. 4123-4132
    • Suvas, S.1    Azkur, A.K.2    Kim, B.S.3    Kumaraguru, U.4    Rouse, B.T.5
  • 11
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
    • McGuirk P, McCann C, Mills KH (2002) Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J Exp Med 195:221-231
    • (2002) J Exp Med , vol.195 , pp. 221-231
    • McGuirk, P.1    McCann, C.2    Mills, K.H.3
  • 14
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL (2002) CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420:502-507
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 15
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: Friend or foe in immunity to infection?
    • Mills KH (2004) Regulatory T cells: friend or foe in immunity to infection? Nat Rev Immunol 4:841-855
    • (2004) Nat Rev Immunol , vol.4 , pp. 841-855
    • Mills, K.H.1
  • 16
    • 14844345227 scopus 로고    scopus 로고
    • CD4+ Tregs and immune control
    • Fehervari Z, Sakaguchi S (2004) CD4+ Tregs and immune control. J Clin Invest 114:1209-1217
    • (2004) J Clin Invest , vol.114 , pp. 1209-1217
    • Fehervari, Z.1    Sakaguchi, S.2
  • 17
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • Belkaid Y, Rouse BT (2005) Natural regulatory T cells in infectious disease. Nat Immunol 6:353-360
    • (2005) Nat Immunol , vol.6 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.T.2
  • 18
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy KJ, Powrie F (2001) Regulatory T cells in the control of immune pathology. Nat Immunol 2:816-822
    • (2001) Nat Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 19
    • 4043102582 scopus 로고    scopus 로고
    • Regulatory cells and infectious agents: Detentes cordiale and contraire
    • Rouse BT, Suvas S (2004) Regulatory cells and infectious agents: detentes cordiale and contraire. J Immunol 173:2211-2215
    • (2004) J Immunol , vol.173 , pp. 2211-2215
    • Rouse, B.T.1    Suvas, S.2
  • 20
    • 0034765725 scopus 로고    scopus 로고
    • Recruitment times, proliferation, and apoptosis rates during the CD8(+) T-cell response to lymphocytic choriomeningitis virus
    • De Boer RJ, Oprea M, Antia R, Murali-Krishna K, Ahmed R, Perelson AS (2001) Recruitment times, proliferation, and apoptosis rates during the CD8(+) T-cell response to lymphocytic choriomeningitis virus. J Virol 75:10663-10669
    • (2001) J Virol , vol.75 , pp. 10663-10669
    • De Boer, R.J.1    Oprea, M.2    Antia, R.3    Murali-Krishna, K.4    Ahmed, R.5    Perelson, A.S.6
  • 21
    • 0033850377 scopus 로고    scopus 로고
    • Direct ex vivo kinetic and phenotypic analyses of CD8(+) T-cell responses induced by DNA immunization
    • Hassett DE, Slifka MK, Zhang J, Whitton JL (2000) Direct ex vivo kinetic and phenotypic analyses of CD8(+) T-cell responses induced by DNA immunization. J Virol 74:8286-8291
    • (2000) J Virol , vol.74 , pp. 8286-8291
    • Hassett, D.E.1    Slifka, M.K.2    Zhang, J.3    Whitton, J.L.4
  • 22
    • 32444444613 scopus 로고    scopus 로고
    • Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8 T cell-mediated, TNF-dependent immunopathology
    • Liu F, Feuer R, Hassett DE, Whitton JL (2006) Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8 T cell-mediated, TNF-dependent immunopathology. J Clin Invest 116:465-475
    • (2006) J Clin Invest , vol.116 , pp. 465-475
    • Liu, F.1    Feuer, R.2    Hassett, D.E.3    Whitton, J.L.4
  • 23
    • 3142765421 scopus 로고    scopus 로고
    • Cutting edge: Pulmonary immunopathology mediated by antigen-specific expression of TNF-alpha by antiviral CD8+ T cells
    • Xu L, Yoon H, Zhao MQ, Liu J, Ramana CV, Enelow RI (2004) Cutting edge: pulmonary immunopathology mediated by antigen-specific expression of TNF-alpha by antiviral CD8+ T cells. J Immunol 173:721-725
    • (2004) J Immunol , vol.173 , pp. 721-725
    • Xu, L.1    Yoon, H.2    Zhao, M.Q.3    Liu, J.4    Ramana, C.V.5    Enelow, R.I.6
  • 24
    • 0019428854 scopus 로고
    • Recovery from a viral respiratory infection. I. Influenza pneumonia in normal and T-deficient mice
    • Wells MA, Albrecht P, Ennis FA (1981) Recovery from a viral respiratory infection. I. Influenza pneumonia in normal and T-deficient mice. J Immunol 126:1036-1041
    • (1981) J Immunol , vol.126 , pp. 1036-1041
    • Wells, M.A.1    Albrecht, P.2    Ennis, F.A.3
  • 25
    • 0028153633 scopus 로고
    • Pathologic features of lung biopsy specimens from influenza pneumonia cases
    • Yeldandi AV, Colby TV (1994) Pathologic features of lung biopsy specimens from influenza pneumonia cases. Hum Pathol 25:47-53
    • (1994) Hum Pathol , vol.25 , pp. 47-53
    • Yeldandi, A.V.1    Colby, T.V.2
  • 29
    • 0037105617 scopus 로고    scopus 로고
    • CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load
    • Sousa AE, Carneiro J, Meier-Schellersheim M, Grossman Z, Victorino RM (2002) CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load. J Immunol 169:3400-3406
    • (2002) J Immunol , vol.169 , pp. 3400-3406
    • Sousa, A.E.1    Carneiro, J.2    Meier-Schellersheim, M.3    Grossman, Z.4    Victorino, R.M.5
  • 31
    • 0036499256 scopus 로고    scopus 로고
    • HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells
    • Garba ML, Pilcher CD, Bingham AL, Eron J, Frelinger JA (2002) HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells. J Immunol 168:2247-2254
    • (2002) J Immunol , vol.168 , pp. 2247-2254
    • Garba, M.L.1    Pilcher, C.D.2    Bingham, A.L.3    Eron, J.4    Frelinger, J.A.5
  • 32
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+ CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S (2005) Naturally arising Foxp3-expressing CD25+ CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 6:345-352
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 33
    • 85047692430 scopus 로고    scopus 로고
    • IL-10-producing and naturally occurring CD4+ Tregs: Limiting collateral damage
    • O'Garra A, Vieira PL, Vieira P, Goldfeld AE (2004) IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest 114:1372-1378
    • (2004) J Clin Invest , vol.114 , pp. 1372-1378
    • O'Garra, A.1    Vieira, P.L.2    Vieira, P.3    Goldfeld, A.E.4
  • 34
  • 35
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou I, Sarukhan A, Klein L, von Boehmer H (2002) Origin of regulatory T cells with known specificity for antigen. Nat Immunol 3:756-763
    • (2002) Nat Immunol , vol.3 , pp. 756-763
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    Von Boehmer, H.4
  • 36
    • 2142645808 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
    • Fantini MC, Becker C, Monteleone G, Pallone F, Galle PR, Neurath MF (2004) Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J Immunol 172:5149-5153
    • (2004) J Immunol , vol.172 , pp. 5149-5153
    • Fantini, M.C.1    Becker, C.2    Monteleone, G.3    Pallone, F.4    Galle, P.R.5    Neurath, M.F.6
  • 37
    • 1642454708 scopus 로고    scopus 로고
    • Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process
    • Karim M, Kingsley CI, Bushell AR, Sawitzki BS, Wood KJ (2004) Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process. J Immunol 172:923-928
    • (2004) J Immunol , vol.172 , pp. 923-928
    • Karim, M.1    Kingsley, C.I.2    Bushell, A.R.3    Sawitzki, B.S.4    Wood, K.J.5
  • 39
    • 0035399985 scopus 로고    scopus 로고
    • Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • Thorstenson KM, Khoruts A (2001) Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J Immunol 167:188-195
    • (2001) J Immunol , vol.167 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 40
    • 12444279957 scopus 로고    scopus 로고
    • Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}
    • Rao PE, Petrone AL, Ponath PD (2005) Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}. J Immunol 174:1446-1455
    • (2005) J Immunol , vol.174 , pp. 1446-1455
    • Rao, P.E.1    Petrone, A.L.2    Ponath, P.D.3
  • 41
    • 0037108485 scopus 로고    scopus 로고
    • Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors
    • Zheng SG, Gray JD, Ohtsuka K, Yamagiwa S, Horwitz DA (2002) Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors. J Immunol 169:4183-4189
    • (2002) J Immunol , vol.169 , pp. 4183-4189
    • Zheng, S.G.1    Gray, J.D.2    Ohtsuka, K.3    Yamagiwa, S.4    Horwitz, D.A.5
  • 44
    • 0038106763 scopus 로고    scopus 로고
    • Regulation of murine inflammatory bowel disease by CD25+ and CD25- CD4+ glucocorticoid-induced TNF receptor family-related gene+ regulatory T cells
    • Uraushihara K, Kanai T, Ko K, Totsuka T, Makita S, Iiyama R, Nakamura T, Watanabe M (2003) Regulation of murine inflammatory bowel disease by CD25+ and CD25- CD4+ glucocorticoid-induced TNF receptor family-related gene+ regulatory T cells. J Immunol 171:708-716
    • (2003) J Immunol , vol.171 , pp. 708-716
    • Uraushihara, K.1    Kanai, T.2    Ko, K.3    Totsuka, T.4    Makita, S.5    Iiyama, R.6    Nakamura, T.7    Watanabe, M.8
  • 46
    • 0036604283 scopus 로고    scopus 로고
    • Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance
    • Graca L, Thompson S, Lin CY, Adams E, Cobbold SP, Waldmann H (2002) Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance. J Immunol 168:5558-5565
    • (2002) J Immunol , vol.168 , pp. 5558-5565
    • Graca, L.1    Thompson, S.2    Lin, C.Y.3    Adams, E.4    Cobbold, S.P.5    Waldmann, H.6
  • 47
    • 15444379874 scopus 로고    scopus 로고
    • Cross-linking of CD45 on suppressive/regulatory T cells leads to the abrogation of their suppressive activity in vitro
    • Shimizu J, Iida R, Sato Y, Moriizumi E, Nishikawa A, Ishida Y (2005) Cross-linking of CD45 on suppressive/regulatory T cells leads to the abrogation of their suppressive activity in vitro. J Immunol 174:4090-4097
    • (2005) J Immunol , vol.174 , pp. 4090-4097
    • Shimizu, J.1    Iida, R.2    Sato, Y.3    Moriizumi, E.4    Nishikawa, A.5    Ishida, Y.6
  • 48
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science 299:1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 49
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F (2003) An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 4:337-342
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 50
    • 33644837829 scopus 로고    scopus 로고
    • In vitro suppression of CD8+ T cell function by friend virus-induced regulatory T cells
    • Robertson SJ, Messer RJ, Carmody AB, Hasenkrug KJ (2006) In vitro suppression of CD8+ T cell function by friend virus-induced regulatory T cells. J Immunol 176:3342-3349
    • (2006) J Immunol , vol.176 , pp. 3342-3349
    • Robertson, S.J.1    Messer, R.J.2    Carmody, A.B.3    Hasenkrug, K.J.4
  • 54
    • 32044462951 scopus 로고    scopus 로고
    • Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects
    • Krathwohl MD, Schacker TW, Anderson JL (2006) Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects. J Infect Dis 193:494-504
    • (2006) J Infect Dis , vol.193 , pp. 494-504
    • Krathwohl, M.D.1    Schacker, T.W.2    Anderson, J.L.3
  • 55
    • 13944284140 scopus 로고    scopus 로고
    • Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation
    • Voo KS, Peng G, Guo Z, Fu T, Li Y, Frappier L, Wang RF (2005) Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation. Cancer Res 65:1577-1586
    • (2005) Cancer Res , vol.65 , pp. 1577-1586
    • Voo, K.S.1    Peng, G.2    Guo, Z.3    Fu, T.4    Li, Y.5    Frappier, L.6    Wang, R.F.7
  • 56
    • 0038280092 scopus 로고    scopus 로고
    • Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1
    • Marshall NA, Vickers MA, Barker RN (2003) Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1. J Immunol 170:6183-6189
    • (2003) J Immunol , vol.170 , pp. 6183-6189
    • Marshall, N.A.1    Vickers, M.A.2    Barker, R.N.3
  • 58
    • 22044447704 scopus 로고    scopus 로고
    • TCRalphabeta repertoire diversity of human naturally occurring CD4+CD25+ regulatory T cells
    • Fujishima M, Hirokawa M, Fujishima N, Sawada K (2005) TCRalphabeta repertoire diversity of human naturally occurring CD4+CD25+ regulatory T cells. Immunol Lett 99:193-197
    • (2005) Immunol Lett , vol.99 , pp. 193-197
    • Fujishima, M.1    Hirokawa, M.2    Fujishima, N.3    Sawada, K.4
  • 59
    • 0037080183 scopus 로고    scopus 로고
    • Peptide specificity of thymic selection of CD4+CD25+ T cells
    • Pacholczyk R, Kraj P, Ignatowicz L (2002) Peptide specificity of thymic selection of CD4+CD25+ T cells. J Immunol 168:613-620
    • (2002) J Immunol , vol.168 , pp. 613-620
    • Pacholczyk, R.1    Kraj, P.2    Ignatowicz, L.3
  • 61
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi T, Kuniyasu Y, Toda M, Sakaguchi N, Itoh M, Iwata M, Shimizu J, Sakaguchi S (1998) Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 10:1969-1980
    • (1998) Int Immunol , vol.10 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3    Sakaguchi, N.4    Itoh, M.5    Iwata, M.6    Shimizu, J.7    Sakaguchi, S.8
  • 62
    • 0043244867 scopus 로고    scopus 로고
    • Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo
    • Walker LS, Chodos A, Eggena M, Dooms H, Abbas AK (2003) Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med 198:249-258
    • (2003) J Exp Med , vol.198 , pp. 249-258
    • Walker, L.S.1    Chodos, A.2    Eggena, M.3    Dooms, H.4    Abbas, A.K.5
  • 63
    • 2142756584 scopus 로고    scopus 로고
    • Antigen-specific T cell repertoire modification of CD4+ CD25+ regulatory T cells
    • Hayashi Y, Tsukumo S, Shiota H, Kishihara K, Yasutomo K (2004) Antigen-specific T cell repertoire modification of CD4+ CD25+ regulatory T cells. J Immunol 172:5240-5248
    • (2004) J Immunol , vol.172 , pp. 5240-5248
    • Hayashi, Y.1    Tsukumo, S.2    Shiota, H.3    Kishihara, K.4    Yasutomo, K.5
  • 64
    • 0042512461 scopus 로고    scopus 로고
    • Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
    • Yamazaki S, Iyoda T, Tarbell K, Olson K, Velinzon K, Inaba K, Steinman RM(2003) Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J Exp Med 198:235-247
    • (2003) J Exp Med , vol.198 , pp. 235-247
    • Yamazaki, S.1    Iyoda, T.2    Tarbell, K.3    Olson, K.4    Velinzon, K.5    Inaba, K.6    Steinman, R.M.7
  • 65
    • 20344397363 scopus 로고    scopus 로고
    • Peripheral generation and function of CD4+CD25+ regulatory T cells
    • Taams LS, Akbar AN (2005) Peripheral generation and function of CD4+CD25+ regulatory T cells. Curr Top Microbiol Immunol 293:115-131
    • (2005) Curr Top Microbiol Immunol , vol.293 , pp. 115-131
    • Taams, L.S.1    Akbar, A.N.2
  • 66
    • 2342663126 scopus 로고    scopus 로고
    • Whither T-suppressors: If they didn't exist would we have to invent them?
    • Cohn M (2004) Whither T-suppressors: if they didn't exist would we have to invent them? Cell Immunol 227:81-92
    • (2004) Cell Immunol , vol.227 , pp. 81-92
    • Cohn, M.1
  • 67
    • 1842480959 scopus 로고    scopus 로고
    • TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
    • Peng Y, Laouar Y, Li MO, Green EA, Flavell RA (2004) TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc Natl Acad Sci U S A 101:4572-4577
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4572-4577
    • Peng, Y.1    Laouar, Y.2    Li, M.O.3    Green, E.A.4    Flavell, R.A.5
  • 68
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGFβ in the differentiation and effector function of T regulatory cells
    • Levings MK, Bacchetta R, Schulz U, Roncarolo MG (2002) The role of IL-10 and TGFβ in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol 129:263-276
    • (2002) Int Arch Allergy Immunol , vol.129 , pp. 263-276
    • Levings, M.K.1    Bacchetta, R.2    Schulz, U.3    Roncarolo, M.G.4
  • 69
    • 0025335354 scopus 로고
    • Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI
    • Moore KW, Vieira P, Fiorentino DF, Trounstine ML, Khan TA, Mosmann TR (1990) Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science 248:1230-1234
    • (1990) Science , vol.248 , pp. 1230-1234
    • Moore, K.W.1    Vieira, P.2    Fiorentino, D.F.3    Trounstine, M.L.4    Khan, T.A.5    Mosmann, T.R.6
  • 70
    • 16244371348 scopus 로고    scopus 로고
    • Preferential feline immunodeficiency virus (FIV) infection of CD4+ CD25+ T-regulatory cells correlates both with surface expression of CXCR4 and activation of FIV long terminal repeat binding cellular transcriptional factors
    • Joshi A, Garg H, Tompkins MB, Tompkins WA (2005) Preferential feline immunodeficiency virus (FIV) infection of CD4+ CD25+ T-regulatory cells correlates both with surface expression of CXCR4 and activation of FIV long terminal repeat binding cellular transcriptional factors. J Virol 79:4965-4976
    • (2005) J Virol , vol.79 , pp. 4965-4976
    • Joshi, A.1    Garg, H.2    Tompkins, M.B.3    Tompkins, W.A.4
  • 71
    • 1642480365 scopus 로고    scopus 로고
    • Feline immunodeficiency virus infection phenotypically and functionally activates immunosuppressive CD4+CD25+ T regulatory cells
    • Vahlenkamp TW, Tompkins MB, Tompkins WA (2004) Feline immunodeficiency virus infection phenotypically and functionally activates immunosuppressive CD4+CD25+ T regulatory cells. J Immunol 172:4752-4761
    • (2004) J Immunol , vol.172 , pp. 4752-4761
    • Vahlenkamp, T.W.1    Tompkins, M.B.2    Tompkins, W.A.3
  • 72
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?
    • Lutz MB, Schuler G (2002) Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23:445-449
    • (2002) Trends Immunol , vol.23 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 73
    • 31544438818 scopus 로고    scopus 로고
    • Virus-stimulated plasmacytoid dendritic cells induce CD4+ cytotoxic regulatory T cells
    • Kawamura K, Kadowaki N, Kitawaki T, Uchiyama T (2006) Virus-stimulated plasmacytoid dendritic cells induce CD4+ cytotoxic regulatory T cells. Blood 107:1031-1038
    • (2006) Blood , vol.107 , pp. 1031-1038
    • Kawamura, K.1    Kadowaki, N.2    Kitawaki, T.3    Uchiyama, T.4
  • 74
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
    • Kadowaki N, Ho S, Antonenko S, Malefyt RW, Kastelein RA, Bazan F, Liu YJ (2001) Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 194:863-869
    • (2001) J Exp Med , vol.194 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    Malefyt, R.W.4    Kastelein, R.A.5    Bazan, F.6    Liu, Y.J.7
  • 75
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
    • Steinman RM, Nussenzweig MC (2002) Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci U S A 99:351-358
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 76
    • 0035862336 scopus 로고    scopus 로고
    • Differentiation of T regulatory cells by immature dendritic cells
    • Roncarolo MG, Levings MK, Traversari C (2001) Differentiation of T regulatory cells by immature dendritic cells. J Exp Med 193:F5-9
    • (2001) J Exp Med , vol.193
    • Roncarolo, M.G.1    Levings, M.K.2    Traversari, C.3
  • 77
    • 2442684197 scopus 로고    scopus 로고
    • HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
    • Granelli-Piperno A, Golebiowska A, Trumpfheller C, Siegal FP, Steinman RM (2004) HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation. Proc Natl Acad Sci U S A 101:7669-7674
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 7669-7674
    • Granelli-Piperno, A.1    Golebiowska, A.2    Trumpfheller, C.3    Siegal, F.P.4    Steinman, R.M.5
  • 78
    • 2542426543 scopus 로고    scopus 로고
    • The paradox of simian immunodeficiency virus infection in sooty mangabeys: Active viral replication without disease progression
    • Chakrabarti LA (2004) The paradox of simian immunodeficiency virus infection in sooty mangabeys: active viral replication without disease progression. Front Biosci 9:521-539
    • (2004) Front Biosci , vol.9 , pp. 521-539
    • Chakrabarti, L.A.1
  • 79
    • 0033861039 scopus 로고    scopus 로고
    • High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys
    • Diop OM, Gueye A, Dias-Tavares M, Kornfeld C, Faye A, Ave P, Huerre M, Corbet S, Barre-Sinoussi F, Muller-Trutwin MC (2000) High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys. J Virol 74:7538-7547
    • (2000) J Virol , vol.74 , pp. 7538-7547
    • Diop, O.M.1    Gueye, A.2    Dias-Tavares, M.3    Kornfeld, C.4    Faye, A.5    Ave, P.6    Huerre, M.7    Corbet, S.8    Barre-Sinoussi, F.9    Muller-Trutwin, M.C.10
  • 80
    • 0037343278 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia
    • Silvestri G, Sodora DL, Koup RA, Paiardini M, O'Neil SP, McClure HM, Staprans SI, Feinberg MB (2003) Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia. Immunity 18:441-452
    • (2003) Immunity , vol.18 , pp. 441-452
    • Silvestri, G.1    Sodora, D.L.2    Koup, R.A.3    Paiardini, M.4    O'Neil, S.P.5    McClure, H.M.6    Staprans, S.I.7    Feinberg, M.B.8
  • 82
    • 0037450746 scopus 로고    scopus 로고
    • Control of immune responses by naturally arising CD4(+) regulatory T cells that express toll-like receptors
    • Sakaguchi S (2003) Control of immune responses by naturally arising CD4(+) regulatory T cells that express toll-like receptors. J Exp Med 197:397-401
    • (2003) J Exp Med , vol.197 , pp. 397-401
    • Sakaguchi, S.1
  • 86
  • 89
    • 0034996027 scopus 로고    scopus 로고
    • Characterization of novel HLA-DR11-restricted HCV epitopes reveals both qualitative and quantitative differences in HCV-specific CD4+ T cell responses in chronically infected and non-viremic patients
    • Godkin A, Jeanguet N, Thursz M, Openshaw P, Thomas H (2001) Characterization of novel HLA-DR11-restricted HCV epitopes reveals both qualitative and quantitative differences in HCV-specific CD4+ T cell responses in chronically infected and non-viremic patients. Eur J Immunol 31:1438-1446
    • (2001) Eur J Immunol , vol.31 , pp. 1438-1446
    • Godkin, A.1    Jeanguet, N.2    Thursz, M.3    Openshaw, P.4    Thomas, H.5
  • 93
    • 0033992625 scopus 로고    scopus 로고
    • Cell mediated immune response to the hepatitis C virus
    • Rehermann B, Chisari FV (2000) Cell mediated immune response to the hepatitis C virus. Curr Top Microbiol Immunol 242:299-325
    • (2000) Curr Top Microbiol Immunol , vol.242 , pp. 299-325
    • Rehermann, B.1    Chisari, F.V.2
  • 94
    • 0345017746 scopus 로고    scopus 로고
    • Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection
    • Sugimoto K, Ikeda F, Stadanlick J, Nunes FA, Alter HJ, Chang KM (2003) Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection. Hepatology 38:1437-1448
    • (2003) Hepatology , vol.38 , pp. 1437-1448
    • Sugimoto, K.1    Ikeda, F.2    Stadanlick, J.3    Nunes, F.A.4    Alter, H.J.5    Chang, K.M.6
  • 95
    • 7044247947 scopus 로고    scopus 로고
    • An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection
    • Cabrera R, Tu Z, Xu Y, Firpi RJ, Rosen HR, Liu C, Nelson DR (2004) An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. Hepatology 40:1062-1071
    • (2004) Hepatology , vol.40 , pp. 1062-1071
    • Cabrera, R.1    Tu, Z.2    Xu, Y.3    Firpi, R.J.4    Rosen, H.R.5    Liu, C.6    Nelson, D.R.7
  • 96
    • 19944370822 scopus 로고    scopus 로고
    • T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection
    • Boettler T, Spangenberg HC, Neumann-Haefelin C, Panther E, Urbani S, Ferrari C, Blum HE, von Weizsacker F, Thimme R (2005) T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. J Virol 79:7860-7867
    • (2005) J Virol , vol.79 , pp. 7860-7867
    • Boettler, T.1    Spangenberg, H.C.2    Neumann-Haefelin, C.3    Panther, E.4    Urbani, S.5    Ferrari, C.6    Blum, H.E.7    Von Weizsacker, F.8    Thimme, R.9
  • 97
    • 19944366276 scopus 로고    scopus 로고
    • Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection
    • Rushbrook SM, Ward SM, Unitt E, Vowler SL, Lucas M, Klenerman P, Alexander GJ (2005) Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection. J Virol 79:7852-7859
    • (2005) J Virol , vol.79 , pp. 7852-7859
    • Rushbrook, S.M.1    Ward, S.M.2    Unitt, E.3    Vowler, S.L.4    Lucas, M.5    Klenerman, P.6    Alexander, G.J.7
  • 100
    • 1942456867 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis
    • Boyer O, Saadoun D, Abriol J, Dodille M, Piette JC, Cacoub P, Klatzmann D (2004) CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis. Blood 103:3428-3430
    • (2004) Blood , vol.103 , pp. 3428-3430
    • Boyer, O.1    Saadoun, D.2    Abriol, J.3    Dodille, M.4    Piette, J.C.5    Cacoub, P.6    Klatzmann, D.7
  • 104
    • 16844378685 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
    • Ormandy LA, Hillemann T, Wedemeyer H, Manns MP, Greten TF, Korangy F (2005) Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res 65:2457-2464
    • (2005) Cancer Res , vol.65 , pp. 2457-2464
    • Ormandy, L.A.1    Hillemann, T.2    Wedemeyer, H.3    Manns, M.P.4    Greten, T.F.5    Korangy, F.6
  • 106
    • 8644280556 scopus 로고    scopus 로고
    • Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
    • Weiss L, Donkova-Petrini V, Caccavelli L, Balbo M, Carbonneil C, Levy Y (2004) Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 104:3249-3256
    • (2004) Blood , vol.104 , pp. 3249-3256
    • Weiss, L.1    Donkova-Petrini, V.2    Caccavelli, L.3    Balbo, M.4    Carbonneil, C.5    Levy, Y.6
  • 107
    • 10744227590 scopus 로고    scopus 로고
    • Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens
    • Aandahl EM, Michaelsson J, Moretto WJ, Hecht FM, Nixon DF (2004) Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J Virol 78:2454-2459
    • (2004) J Virol , vol.78 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 108
    • 3543098686 scopus 로고    scopus 로고
    • CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
    • Kinter AL, Hennessey M, Bell A, Kern S, Lin Y, Daucher M, Planta M, McGlaughlin M, Jackson R, Ziegler SF, Fauci AS (2004) CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med 200:331-343
    • (2004) J Exp Med , vol.200 , pp. 331-343
    • Kinter, A.L.1    Hennessey, M.2    Bell, A.3    Kern, S.4    Lin, Y.5    Daucher, M.6    Planta, M.7    McGlaughlin, M.8    Jackson, R.9    Ziegler, S.F.10    Fauci, A.S.11
  • 111
    • 0024786954 scopus 로고
    • Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging
    • Clerici M, Stocks NI, Zajac RA, Boswell RN, Lucey DR, Via CS, Shearer GM (1989) Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging. J Clin Invest 84:1892-1899
    • (1989) J Clin Invest , vol.84 , pp. 1892-1899
    • Clerici, M.1    Stocks, N.I.2    Zajac, R.A.3    Boswell, R.N.4    Lucey, D.R.5    Via, C.S.6    Shearer, G.M.7
  • 112
    • 0031973577 scopus 로고    scopus 로고
    • Circulating CD8 T lymphocytes in human immunodeficiency virus-infected individuals have impaired function and downmodulate CD3 zeta, the signaling chain of the T-cell receptor complex
    • Trimble LA, Lieberman J (1998) Circulating CD8 T lymphocytes in human immunodeficiency virus-infected individuals have impaired function and downmodulate CD3 zeta, the signaling chain of the T-cell receptor complex. Blood 91:585-594
    • (1998) Blood , vol.91 , pp. 585-594
    • Trimble, L.A.1    Lieberman, J.2
  • 118
    • 0026517545 scopus 로고
    • Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals
    • Groux H, Torpier G, Monte D, Mouton Y, Capron A, Ameisen JC (1992) Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals. J Exp Med 175:331-340
    • (1992) J Exp Med , vol.175 , pp. 331-340
    • Groux, H.1    Torpier, G.2    Monte, D.3    Mouton, Y.4    Capron, A.5    Ameisen, J.C.6
  • 121
    • 17444407451 scopus 로고    scopus 로고
    • Cutting edge: The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients
    • Andersson J, Boasso A, Nilsson J, Zhang R, Shire NJ, Lindback S, Shearer GM, Chougnet CA (2005) Cutting edge: the prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients. J Immunol 174:3143-3147
    • (2005) J Immunol , vol.174 , pp. 3143-3147
    • Andersson, J.1    Boasso, A.2    Nilsson, J.3    Zhang, R.4    Shire, N.J.5    Lindback, S.6    Shearer, G.M.7    Chougnet, C.A.8
  • 122
    • 0142092389 scopus 로고    scopus 로고
    • Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
    • Guadalupe M, Reay E, Sankaran S, Prindiville T, Flamm J, McNeil A, Dandekar S (2003) Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J Virol 77:11708-11717
    • (2003) J Virol , vol.77 , pp. 11708-11717
    • Guadalupe, M.1    Reay, E.2    Sankaran, S.3    Prindiville, T.4    Flamm, J.5    McNeil, A.6    Dandekar, S.7
  • 123
    • 0032971372 scopus 로고    scopus 로고
    • Population biology of HIV-1 infection: Viral and CD4+ T cell demographics and dynamics in lymphatic tissues
    • Haase AT (1999) Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues. Annu Rev Immunol 17:625-656
    • (1999) Annu Rev Immunol , vol.17 , pp. 625-656
    • Haase, A.T.1
  • 124
    • 22244451393 scopus 로고    scopus 로고
    • Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors
    • Sankaran S, Guadalupe M, Reay E, George MD, Flamm J, Prindiville T, Dandekar S (2005) Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors. Proc Natl Acad Sci U S A 102:9860-9865
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 9860-9865
    • Sankaran, S.1    Guadalupe, M.2    Reay, E.3    George, M.D.4    Flamm, J.5    Prindiville, T.6    Dandekar, S.7
  • 127
    • 0037018104 scopus 로고    scopus 로고
    • In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, de Waal-Malefyt R, Coffman RL, Hawrylowicz CM, O'Garra A (2002) In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 195:603-616
    • (2002) J Exp Med , vol.195 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3    Richards, D.F.4    Crain, C.5    Savelkoul, H.F.6    De Waal-Malefyt, R.7    Coffman, R.L.8    Hawrylowicz, C.M.9    O'Garra, A.10
  • 128
    • 0035890108 scopus 로고    scopus 로고
    • Quantitative and qualitative assessment of human immunodeficiency virus type 1 (HIV-1)-specific CD4+ T cell immunity to gag in HIV-1-infected individuals with differential disease progression: Reciprocal interferon-gamma and interleukin-10 responses
    • Ostrowski MA, Gu JX, Kovacs C, Freedman J, Luscher MA, MacDonald KS (2001) Quantitative and qualitative assessment of human immunodeficiency virus type 1 (HIV-1)-specific CD4+ T cell immunity to gag in HIV-1-infected individuals with differential disease progression: reciprocal interferon-gamma and interleukin-10 responses. J Infect Dis 184:1268-1278
    • (2001) J Infect Dis , vol.184 , pp. 1268-1278
    • Ostrowski, M.A.1    Gu, J.X.2    Kovacs, C.3    Freedman, J.4    Luscher, M.A.5    MacDonald, K.S.6
  • 129
    • 1642577126 scopus 로고    scopus 로고
    • TGF-beta1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice
    • Nakamura K, Kitani A, Fuss I, Pedersen A, Harada N, Nawata H, Strober W (2004) TGF-beta1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J Immunol 172:834-842
    • (2004) J Immunol , vol.172 , pp. 834-842
    • Nakamura, K.1    Kitani, A.2    Fuss, I.3    Pedersen, A.4    Harada, N.5    Nawata, H.6    Strober, W.7
  • 131
    • 0141703239 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes
    • Green EA, Gorelik L, McGregor CM, Tran EH, Flavell RA (2003) CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes. Proc Natl Acad Sci U S A 100:10878-10883
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10878-10883
    • Green, E.A.1    Gorelik, L.2    McGregor, C.M.3    Tran, E.H.4    Flavell, R.A.5
  • 132
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer H (2005) Mechanisms of suppression by suppressor T cells. Nat Immunol 6:338-344
    • (2005) Nat Immunol , vol.6 , pp. 338-344
    • Von Boehmer, H.1
  • 133
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • Fontenot JD, Rudensky AY (2005) A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol 6:331-337
    • (2005) Nat Immunol , vol.6 , pp. 331-337
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 134
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4:330-336
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 135
    • 2942674466 scopus 로고    scopus 로고
    • Foxp3: A critical regulator of the development and function of regulatory T cells
    • Hori S, Sakaguchi S (2004) Foxp3: a critical regulator of the development and function of regulatory T cells. Microbes Infect 6:745-751
    • (2004) Microbes Infect , vol.6 , pp. 745-751
    • Hori, S.1    Sakaguchi, S.2
  • 137
    • 0042591467 scopus 로고    scopus 로고
    • Cutting edge: Induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion
    • Mellor AL, Baban B, Chandler P, Marshall B, Jhaver K, Hansen A, Koni PA, Iwashima M, Munn DH (2003) Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion. J Immunol 171:1652-1655
    • (2003) J Immunol , vol.171 , pp. 1652-1655
    • Mellor, A.L.1    Baban, B.2    Chandler, P.3    Marshall, B.4    Jhaver, K.5    Hansen, A.6    Koni, P.A.7    Iwashima, M.8    Munn, D.H.9
  • 140
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton AM, Shevach EM (2000) Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 164:183-190
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 141
    • 23244458132 scopus 로고    scopus 로고
    • CD8+ T-Cell dysfunction due to cytolytic granule deficiency in persistent friend retrovirus infection
    • Zelinskyy G, Robertson SJ, Schimmer S, Messer RJ, Hasenkrug KJ, Dittmer U (2005) CD8+ T-Cell dysfunction due to cytolytic granule deficiency in persistent friend retrovirus infection. J Virol 79:10619-10626
    • (2005) J Virol , vol.79 , pp. 10619-10626
    • Zelinskyy, G.1    Robertson, S.J.2    Schimmer, S.3    Messer, R.J.4    Hasenkrug, K.J.5    Dittmer, U.6
  • 142
    • 14844365222 scopus 로고    scopus 로고
    • The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen
    • Bushell A, Jones E, Gallimore A, Wood K (2005) The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen. J Immunol 174:3290-3297
    • (2005) J Immunol , vol.174 , pp. 3290-3297
    • Bushell, A.1    Jones, E.2    Gallimore, A.3    Wood, K.4
  • 143
    • 0141449974 scopus 로고    scopus 로고
    • CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses
    • Suvas S, Kumaraguru U, Pack CD, Lee S, Rouse BT (2003) CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses. J Exp Med 198:889-901
    • (2003) J Exp Med , vol.198 , pp. 889-901
    • Suvas, S.1    Kumaraguru, U.2    Pack, C.D.3    Lee, S.4    Rouse, B.T.5
  • 144
    • 8644290853 scopus 로고    scopus 로고
    • CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1
    • Toka FN, Suvas S, Rouse BT (2004) CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1. J Virol 78:13082-13089
    • (2004) J Virol , vol.78 , pp. 13082-13089
    • Toka, F.N.1    Suvas, S.2    Rouse, B.T.3
  • 145
    • 14744271751 scopus 로고    scopus 로고
    • Modulation of the CD8+T-cell response by CD4+ CD25+ regulatory T cells in patients with hepatitis B virus infection
    • Franzese O, Kennedy PT, Gehring AJ, Gotto J, Williams R, Maini MK, Bertoletti A (2005) Modulation of the CD8+T-cell response by CD4+ CD25+ regulatory T cells in patients with hepatitis B virus infection. J Virol 79:3322-3328
    • (2005) J Virol , vol.79 , pp. 3322-3328
    • Franzese, O.1    Kennedy, P.T.2    Gehring, A.J.3    Gotto, J.4    Williams, R.5    Maini, M.K.6    Bertoletti, A.7
  • 148
    • 25844507839 scopus 로고    scopus 로고
    • Possible origin of adult T-cell leukemia/lymphoma cells from human T lymphotropic virus type-1-infected regulatory T cells
    • Kohno T, Yamada Y, Akamatsu N, Kamihira S, Imaizumi Y, Tomonaga M, Matsuyama T (2005) Possible origin of adult T-cell leukemia/lymphoma cells from human T lymphotropic virus type-1-infected regulatory T cells. Cancer Sci 96:527-533
    • (2005) Cancer Sci , vol.96 , pp. 527-533
    • Kohno, T.1    Yamada, Y.2    Akamatsu, N.3    Kamihira, S.4    Imaizumi, Y.5    Tomonaga, M.6    Matsuyama, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.