메뉴 건너뛰기




Volumn 6, Issue 8, 2004, Pages 745-751

Foxp3: A critical regulator of the development and function of regulatory T cells

Author keywords

antigen presenting cell; APC; Autoimmunity; CTLA 4; cytotoxic T lymphocyte antigen 4; Foxp3; GITR; glucocorticoid induced tumor necrosis factor receptor related protein; IFN ; Immune regulation; Immunological tolerance; Regulatory T cells

Indexed keywords

CD4 ANTIGEN; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; SUPPRESSOR FACTOR; TUMOR GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 2942674466     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micinf.2004.02.020     Document Type: Short Survey
Times cited : (255)

References (40)
  • 1
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S., Sakaguchi N., Shimizu J., Yamazaki S., Sakihama T., Itoh M., Kuniyasu Y., Nomura T., Toda M., Takahashi T. Immunologic tolerance maintained by CD25+CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 182:2001;18-32
    • (2001) Immunol. Rev. , vol.182 , pp. 18-32
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3    Yamazaki, S.4    Sakihama, T.5    Itoh, M.6    Kuniyasu, Y.7    Nomura, T.8    Toda, M.9    Takahashi, T.10
  • 2
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy K.J., Powrie F. Regulatory T cells in the control of immune pathology. Nat. Immunol. 2:2001;816-822
    • (2001) Nat. Immunol. , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 3
    • 0036597371 scopus 로고    scopus 로고
    • CD4+CD25+ suppressor T cells: More questions than answers
    • Shevach E.M. CD4+CD25+ suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2:2002;389-400
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 4
    • 0035181730 scopus 로고    scopus 로고
    • Regulatory T cells: The physiology of autoreactivity in dominant tolerance and "quality control" of immune responses
    • Coutinho A., Hori S., Carvalho T., Caramalho I., Demengeot J. Regulatory T cells: the physiology of autoreactivity in dominant tolerance and "quality control" of immune responses. Immunol. Rev. 182:2001;89-98
    • (2001) Immunol. Rev. , vol.182 , pp. 89-98
    • Coutinho, A.1    Hori, S.2    Carvalho, T.3    Caramalho, I.4    Demengeot, J.5
  • 6
    • 0242407713 scopus 로고    scopus 로고
    • Control of immune homeostasis by naturally arising regulatory CD4+ T cells
    • Gavin M., Rudensky A. Control of immune homeostasis by naturally arising regulatory CD4+ T cells. Curr. Opin. Immunol. 15:2003;690-696
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 690-696
    • Gavin, M.1    Rudensky, A.2
  • 7
    • 0346888498 scopus 로고    scopus 로고
    • Control of autoimmunity by naturally arising regulatory CD4+ T cells
    • Hori S., Takahashi T., Sakaguchi S. Control of autoimmunity by naturally arising regulatory CD4+ T cells. Adv. Immunol. 81:2003;331-371
    • (2003) Adv. Immunol. , vol.81 , pp. 331-371
    • Hori, S.1    Takahashi, T.2    Sakaguchi, S.3
  • 8
    • 0036919854 scopus 로고    scopus 로고
    • Peripheral expansion of thymus-derived regulatory cells in anti-myelin basic protein T cell receptor transgenic mice
    • Hori S., Haury M., Lafaille J.J., Demengeot J., Coutinho A. Peripheral expansion of thymus-derived regulatory cells in anti-myelin basic protein T cell receptor transgenic mice. Eur. J. Immunol. 32:2002;3729-3735
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3729-3735
    • Hori, S.1    Haury, M.2    Lafaille, J.J.3    Demengeot, J.4    Coutinho, A.5
  • 10
    • 0043244867 scopus 로고    scopus 로고
    • Antigen-dependent proliferation of CD4+CD25+ regulatory T cells in vivo
    • Walker L.S., Chodos A., Eggena M., Dooms H., Abbas A.K. Antigen-dependent proliferation of CD4+CD25+ regulatory T cells in vivo. J. Exp. Med. 198:2003;249-258
    • (2003) J. Exp. Med. , vol.198 , pp. 249-258
    • Walker, L.S.1    Chodos, A.2    Eggena, M.3    Dooms, H.4    Abbas, A.K.5
  • 11
    • 0041806547 scopus 로고    scopus 로고
    • In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro
    • Klein L., Khazaie K., von Boehmer H. In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro. Proc. Natl. Acad. Sci. USA. 100:2003;8886-8891
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8886-8891
    • Klein, L.1    Khazaie, K.2    Von Boehmer, H.3
  • 12
    • 0042512461 scopus 로고    scopus 로고
    • Direct expansion of functional CD25+CD4+ regulatory T cells by antigen-processing dendritic cells
    • Yamazaki S., Iyoda T., Tarbell K., Olson K., Velinzon K., Inaba K., Steinman R.M. Direct expansion of functional CD25+CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198:2003;235-247
    • (2003) J. Exp. Med. , vol.198 , pp. 235-247
    • Yamazaki, S.1    Iyoda, T.2    Tarbell, K.3    Olson, K.4    Velinzon, K.5    Inaba, K.6    Steinman, R.M.7
  • 13
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone J.A., Abbas A.K. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3:2003;253-257
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 15
    • 0037131969 scopus 로고    scopus 로고
    • Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells
    • Levings M.K., Sangregorio R., Sartirana C., Moschin A.L., Battaglia M., Orban P.C., Roncarolo M.G. Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J. Exp. Med. 196:2002;1335-1346
    • (2002) J. Exp. Med. , vol.196 , pp. 1335-1346
    • Levings, M.K.1    Sangregorio, R.2    Sartirana, C.3    Moschin, A.L.4    Battaglia, M.5    Orban, P.C.6    Roncarolo, M.G.7
  • 16
    • 0033136302 scopus 로고    scopus 로고
    • Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • Itoh M., Takahashi T., Sakaguchi N., Kuniyasu Y., Shimizu J., Otsuka F., Sakaguchi S. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162:1999;5317-5326
    • (1999) J. Immunol. , vol.162 , pp. 5317-5326
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3    Kuniyasu, Y.4    Shimizu, J.5    Otsuka, F.6    Sakaguchi, S.7
  • 18
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou I., Sarukhan A., Klein L., von Boehmer H. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3:2002;756-763
    • (2002) Nat. Immunol. , vol.3 , pp. 756-763
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    Von Boehmer, H.4
  • 19
    • 0036568942 scopus 로고    scopus 로고
    • Generation of CD4+CD25+ regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
    • Kawahata K., Misaki Y., Yamauchi M., Tsunekawa S., Setoguchi K., Miyazaki J., Yamamoto K. Generation of CD4+CD25+ regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J. Immunol. 168:2002;4399-4405
    • (2002) J. Immunol. , vol.168 , pp. 4399-4405
    • Kawahata, K.1    Misaki, Y.2    Yamauchi, M.3    Tsunekawa, S.4    Setoguchi, K.5    Miyazaki, J.6    Yamamoto, K.7
  • 20
    • 0035920510 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4+25+ immunoregulatory T cells
    • Bensinger S.J., Bandeira A., Jordan M.S., Caton A.J., Laufer T.M. Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4+25+ immunoregulatory T cells. J. Exp. Med. 194:2001;427-438
    • (2001) J. Exp. Med. , vol.194 , pp. 427-438
    • Bensinger, S.J.1    Bandeira, A.2    Jordan, M.S.3    Caton, A.J.4    Laufer, T.M.5
  • 21
    • 0035399985 scopus 로고    scopus 로고
    • Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • Thorstenson K.M., Khoruts A. Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J. Immunol. 167:2001;188-195
    • (2001) J. Immunol. , vol.167 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 22
    • 0026178213 scopus 로고
    • X-linked lymphoreticular disease in the scurfy (sf) mutant mouse
    • Godfrey V.L., Wilkinson J.E., Russell L.B. X-linked lymphoreticular disease in the scurfy (sf) mutant mouse. Am. J. Pathol. 138:1991;1379-1387
    • (1991) Am. J. Pathol. , vol.138 , pp. 1379-1387
    • Godfrey, V.L.1    Wilkinson, J.E.2    Russell, L.B.3
  • 23
    • 0028171297 scopus 로고
    • CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse
    • Blair P.J., Bultman S.J., Haas J.C., Rouse B.T., Wilkinson J.E., Godfrey V.L. CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse. J. Immunol. 153:1994;3764-3774
    • (1994) J. Immunol. , vol.153 , pp. 3764-3774
    • Blair, P.J.1    Bultman, S.J.2    Haas, J.C.3    Rouse, B.T.4    Wilkinson, J.E.5    Godfrey, V.L.6
  • 24
    • 0035136980 scopus 로고    scopus 로고
    • The murine mutation scurfy (sf) results in an antigen-dependent lymphoproliferative disease with altered T cell sensitivity
    • Zahorsky-Reeves J.L., Wilkinson J.E. The murine mutation scurfy (sf) results in an antigen-dependent lymphoproliferative disease with altered T cell sensitivity. Eur. J. Immunol. 31:2001;196-204
    • (2001) Eur. J. Immunol. , vol.31 , pp. 196-204
    • Zahorsky-Reeves, J.L.1    Wilkinson, J.E.2
  • 26
    • 0035813231 scopus 로고    scopus 로고
    • Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
    • Schubert L.A., Jeffery E., Zhang Y., Ramsdell F., Ziegler S.F. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J. Biol. Chem. 276:2001;37672-37679
    • (2001) J. Biol. Chem. , vol.276 , pp. 37672-37679
    • Schubert, L.A.1    Jeffery, E.2    Zhang, Y.3    Ramsdell, F.4    Ziegler, S.F.5
  • 32
    • 0042346231 scopus 로고    scopus 로고
    • Scurfin (FoxP3) controls T-dependent immune responses in vivo through regulation of CD4+ T cell effector function
    • Kasprowicz D.J., Smallwood P.S., Tyznik A.J., Ziegler S.F. Scurfin (FoxP3) controls T-dependent immune responses in vivo through regulation of CD4+ T cell effector function. J. Immunol. 171:2003;1216-1223
    • (2003) J. Immunol. , vol.171 , pp. 1216-1223
    • Kasprowicz, D.J.1    Smallwood, P.S.2    Tyznik, A.J.3    Ziegler, S.F.4
  • 34
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S., Nomura T., Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 299:2003;1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 35
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot J.D., Gavin M.A., Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4:2003;330-336
    • (2003) Nat. Immunol. , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 36
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for scurfin in CD4+CD25+ T regulatory cells
    • Khattri R., Cox T., Yasayko S.A., Ramsdell F. An essential role for scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4:2003;337-342
    • (2003) Nat. Immunol. , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 39
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen W., Jin W., Hardegen N., Lei K.J., Li L., Marinos N., McGrady G., Wahl S.M. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198:2003;1875-1886
    • (2003) J. Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 40
    • 0037450727 scopus 로고    scopus 로고
    • T cell regulation as a side effect of homeostasis and competition
    • Barthlott T., Kassiotis G., Stockinger B. T cell regulation as a side effect of homeostasis and competition. J. Exp. Med. 197:2003;451-460
    • (2003) J. Exp. Med. , vol.197 , pp. 451-460
    • Barthlott, T.1    Kassiotis, G.2    Stockinger, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.