메뉴 건너뛰기




Volumn 65, Issue 4, 2005, Pages 1577-1586

Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS ANTIGEN; CELL NUCLEUS ANTIGEN 1; HLA DQ2 ANTIGEN; HLA DR ANTIGEN; HLA DR11 ANTIGEN; HLA DR12 ANTIGEN; HLA DR13 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MELANOMA ANTIGEN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 13944284140     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-2552     Document Type: Article
Times cited : (85)

References (46)
  • 1
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: More questions than answers
    • Shevach EM. CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2002;2:389-400.
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 2
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S, Sakaguchi N, Shimizu J, et al. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001;182:18-32.
    • (2001) Immunol Rev , vol.182 , pp. 18-32
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3
  • 3
    • 0034919646 scopus 로고    scopus 로고
    • The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity
    • Wang R-F. The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity. Trends Immunol 2001;22:269-76.
    • (2001) Trends Immunol , vol.22 , pp. 269-276
    • Wang, R.-F.1
  • 4
    • 0037456367 scopus 로고    scopus 로고
    • CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
    • Janssen EM, Lemmens EE, Wolfe T, et al. CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature (Lond) 2003;421:852-56.
    • (2003) Nature (Lond) , vol.421 , pp. 852-856
    • Janssen, E.M.1    Lemmens, E.E.2    Wolfe, T.3
  • 5
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Wash DC
    • Shedlock DJ, Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science (Wash DC) 2003;300:337-9.
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 6
    • 0036289885 scopus 로고    scopus 로고
    • T cell-mediated immune responses in melanoma: Implications for immunotherapy
    • Wang RF, Zeng G, Johnston SF, Voo K, Ying H. T cell-mediated immune responses in melanoma: implications for immunotherapy. Crit Rev Oncol Hematol 2002;43:1-11.
    • (2002) Crit Rev Oncol Hematol , vol.43 , pp. 1-11
    • Wang, R.F.1    Zeng, G.2    Johnston, S.F.3    Voo, K.4    Ying, H.5
  • 7
    • 0033738329 scopus 로고    scopus 로고
    • The role of different subsets of T regulatory cells in controlling autoimmunity
    • Roncarolo MG, Levings MK. The role of different subsets of T regulatory cells in controlling autoimmunity. Curr Opin Immunol 2000;12:676-83.
    • (2000) Curr Opin Immunol , vol.12 , pp. 676-683
    • Roncarolo, M.G.1    Levings, M.K.2
  • 8
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003;3:253-7.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 9
    • 0142250482 scopus 로고    scopus 로고
    • Regulatory T cells under scrutiny
    • Bach JF. Regulatory T cells under scrutiny. Nat Rev Immunol 2003;3:189-98.
    • (2003) Nat Rev Immunol , vol.3 , pp. 189-198
    • Bach, J.F.1
  • 10
    • 0037361819 scopus 로고    scopus 로고
    • Antigen-induced regulatory T cells in autoimmunity
    • von Herrath MG, Harrison LC. Antigen-induced regulatory T cells in autoimmunity. Nat Rev Immunol 2003;3:223-32.
    • (2003) Nat Rev Immunol , vol.3 , pp. 223-232
    • Von Herrath, M.G.1    Harrison, L.C.2
  • 11
    • 9244223651 scopus 로고    scopus 로고
    • Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity
    • Stock P, Akbari O, Berry G, et al. Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nat Immunol 2004;5:1149-56.
    • (2004) Nat Immunol , vol.5 , pp. 1149-1156
    • Stock, P.1    Akbari, O.2    Berry, G.3
  • 12
    • 0032534725 scopus 로고    scopus 로고
    • Induction or protection from experimental autoimmune encephalomyelitis depends on the cytokine secretion profile of TCR peptide-specific regulatory CD4 T cells
    • Kumar V, Sercarz E. Induction or protection from experimental autoimmune encephalomyelitis depends on the cytokine secretion profile of TCR peptide-specific regulatory CD4 T cells. J Immunol 1998;161:6585-91.
    • (1998) J Immunol , vol.161 , pp. 6585-6591
    • Kumar, V.1    Sercarz, E.2
  • 13
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003;3:199-210.
    • (2003) Nat Rev Immunol , vol.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2
  • 14
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Wash DC
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science (Wash DC) 2003;299:1057-61.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 15
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 2003;4:337-42.
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 16
    • 0346969978 scopus 로고    scopus 로고
    • Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells
    • Walker MR, Kasprowicz DJ, Gersuk VH, et al. Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells. J Clin Invest 2003;112:1437-43.
    • (2003) J Clin Invest , vol.112 , pp. 1437-1443
    • Walker, M.R.1    Kasprowicz, D.J.2    Gersuk, V.H.3
  • 17
    • 1642497640 scopus 로고    scopus 로고
    • Tumor-specific human CD4+ regulatory T cells and their ligands: Implications for immunotherapy
    • Wang HY, Lee DA, Peng G, et al. Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy. Immunity 2004;20:107-18.
    • (2004) Immunity , vol.20 , pp. 107-118
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3
  • 18
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-β in the differentiation and effector function of T regulatory cells
    • Levings MK, Bacchetta R, Schulz U, Roncarolo MG. The role of IL-10 and TGF-β in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol 2002;129:263-76.
    • (2002) Int Arch Allergy Immunol , vol.129 , pp. 263-276
    • Levings, M.K.1    Bacchetta, R.2    Schulz, U.3    Roncarolo, M.G.4
  • 19
    • 0021922720 scopus 로고
    • Experimental autoimmune prostatitis after neonatal thymectomy in the mouse
    • Taguchi O, Kojima A, Nishizuka Y. Experimental autoimmune prostatitis after neonatal thymectomy in the mouse. Clin Exp Immunol 1985;60:123-29.
    • (1985) Clin Exp Immunol , vol.60 , pp. 123-129
    • Taguchi, O.1    Kojima, A.2    Nishizuka, Y.3
  • 20
    • 0024458198 scopus 로고
    • Interception of the development of self tolerance in fetal lambs
    • McCullagh P. Interception of the development of self tolerance in fetal lambs. Eur J Immunol 1989;19:1387-92.
    • (1989) Eur J Immunol , vol.19 , pp. 1387-1392
    • McCullagh, P.1
  • 21
    • 0028340056 scopus 로고
    • Epstein-Barr virus strategy in normal and neoplastic B cells
    • Klein G. Epstein-Barr virus strategy in normal and neoplastic B cells. Cell 1994;77:791-3.
    • (1994) Cell , vol.77 , pp. 791-793
    • Klein, G.1
  • 22
    • 1642334164 scopus 로고    scopus 로고
    • Persistence of the Epstein-Barr virus and the origins of associated lymphomas
    • Thorley-Lawson DA, Gross A. Persistence of the Epstein-Barr virus and the origins of associated lymphomas. N Engl J Med 2004;350:1328-37.
    • (2004) N Engl J Med , vol.350 , pp. 1328-1337
    • Thorley-Lawson, D.A.1    Gross, A.2
  • 23
    • 0030889206 scopus 로고    scopus 로고
    • Human cytotoxic T lymphocyte responses to Epstein-Barr virus infection
    • Rickinson AB, Moss DJ. Human cytotoxic T lymphocyte responses to Epstein-Barr virus infection. Annu Rev Immunol 1997;15:405-31.
    • (1997) Annu Rev Immunol , vol.15 , pp. 405-431
    • Rickinson, A.B.1    Moss, D.J.2
  • 24
    • 0030014205 scopus 로고    scopus 로고
    • Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice
    • Wilson JB, Bell JL, Levine AJ. Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice. EMBO J 1996;15:3117-26.
    • (1996) EMBO J , vol.15 , pp. 3117-3126
    • Wilson, J.B.1    Bell, J.L.2    Levine, A.J.3
  • 25
    • 1242343722 scopus 로고    scopus 로고
    • Evidence for the presentation of major histocompatibility complex class I-restricted Epstein-Barr virus nuclear antigen 1 peptides to CD8+ T lymphocytes
    • Voo KS, Fu T, Wang HY, et al. Evidence for the presentation of major histocompatibility complex class I-restricted Epstein-Barr virus nuclear antigen 1 peptides to CD8+ T lymphocytes. J Exp Med 2004;199:459-70.
    • (2004) J Exp Med , vol.199 , pp. 459-470
    • Voo, K.S.1    Fu, T.2    Wang, H.Y.3
  • 26
    • 2542505520 scopus 로고    scopus 로고
    • Endogenous presentation of CD8+ T cell epitopes from Epstein-Barr virus-encoded nuclear antigen 1
    • Tellam J, Connolly G, Green KJ, et al. Endogenous presentation of CD8+ T cell epitopes from Epstein-Barr virus-encoded nuclear antigen 1. J Exp Med 2004;199:1421-31.
    • (2004) J Exp Med , vol.199 , pp. 1421-1431
    • Tellam, J.1    Connolly, G.2    Green, K.J.3
  • 27
    • 2542446376 scopus 로고    scopus 로고
    • CD8 T cell recognition of endogenously expressed Epstein-Barr virus nuclear antigen 1
    • Lee SP, Brooks JM, Al-Jarrah H, et al. CD8 T cell recognition of endogenously expressed Epstein-Barr virus nuclear antigen 1. J Exp Med 2004;199:1409-20.
    • (2004) J Exp Med , vol.199 , pp. 1409-1420
    • Lee, S.P.1    Brooks, J.M.2    Al-Jarrah, H.3
  • 28
    • 0037546559 scopus 로고    scopus 로고
    • CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1
    • Munz C, Bickham KL, Subklewe M, et al. CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1. J Exp Med 2000; 191:1649-60.
    • (2000) J Exp Med , vol.191 , pp. 1649-1660
    • Munz, C.1    Bickham, K.L.2    Subklewe, M.3
  • 29
    • 0034892688 scopus 로고    scopus 로고
    • Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4(+) T-helper 1 responses
    • Leen A, Meij P, Redchenko I, et al. Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4(+) T-helper 1 responses. J Virol 2001;75:8649-59.
    • (2001) J Virol , vol.75 , pp. 8649-8659
    • Leen, A.1    Meij, P.2    Redchenko, I.3
  • 30
    • 0035082499 scopus 로고    scopus 로고
    • CD4+ T-cell effectors inhibit Epstein-Barr virus-induced B-cell proliferation
    • Nikiforow S, Bottomly K, Miller G. CD4+ T-cell effectors inhibit Epstein-Barr virus-induced B-cell proliferation. J Virol 2001;75:3740-52.
    • (2001) J Virol , vol.75 , pp. 3740-3752
    • Nikiforow, S.1    Bottomly, K.2    Miller, G.3
  • 31
    • 0036681812 scopus 로고    scopus 로고
    • Epstein-Barr nuclear antigen 1-specific CD4(+) Th1 cells kill Burkitt's lymphoma cells
    • Paludan C, Bickham K, Nikiforow S, et al. Epstein-Barr nuclear antigen 1-specific CD4(+) Th1 cells kill Burkitt's lymphoma cells. J Immunol 2002; 169:1593-603.
    • (2002) J Immunol , vol.169 , pp. 1593-1603
    • Paludan, C.1    Bickham, K.2    Nikiforow, S.3
  • 32
    • 0037115633 scopus 로고    scopus 로고
    • Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells
    • Voo KS, Fu T, Heslop HE, et al. Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells. Cancer Res 2002;62:7195-9.
    • (2002) Cancer Res , vol.62 , pp. 7195-7199
    • Voo, K.S.1    Fu, T.2    Heslop, H.E.3
  • 33
    • 0041529593 scopus 로고    scopus 로고
    • Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7
    • Holowaty MN, Zeghouf M, Wu H, et al. Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7. J Biol Chem 2003; 278:29987-94.
    • (2003) J Biol Chem , vol.278 , pp. 29987-29994
    • Holowaty, M.N.1    Zeghouf, M.2    Wu, H.3
  • 34
    • 0033082487 scopus 로고    scopus 로고
    • Reevaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers
    • Tan LC, Gudgeon N, Annels NE, et al. Reevaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers. J Immunol 1999; 162:1827-35.
    • (1999) J Immunol , vol.162 , pp. 1827-1835
    • Tan, L.C.1    Gudgeon, N.2    Annels, N.E.3
  • 35
    • 0030472678 scopus 로고    scopus 로고
    • Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes
    • Wang R-F, Appella E, Kawakami Y, Kang X Rosenberg SA. Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes. J Exp Med 1996;184:2207-16.
    • (1996) J Exp Med , vol.184 , pp. 2207-2216
    • Wang, R.-F.1    Appella, E.2    Kawakami, Y.3    Kang, X.4    Rosenberg, S.A.5
  • 36
    • 2942618491 scopus 로고    scopus 로고
    • Down-regulation of IL-2 production in T lymphocytes by phosphorylated protein kinase A-RIIβ
    • Elliott MR, Shanks RA, Khan IU, et al. Down-regulation of IL-2 production in T lymphocytes by phosphorylated protein kinase A-RIIβ. J Immunol 2004;172:7804-12.
    • (2004) J Immunol , vol.172 , pp. 7804-7812
    • Elliott, M.R.1    Shanks, R.A.2    Khan, I.U.3
  • 37
    • 0038176078 scopus 로고    scopus 로고
    • Identification of a naturally processed HLA-DR-restricted T-helper epitope in Epstein-Barr virus nuclear antigen type 1
    • Kruger S, Schroers R, Rooney CM, Gahn B, Chen SY. Identification of a naturally processed HLA-DR-restricted T-helper epitope in Epstein-Barr virus nuclear antigen type 1. J Immunother 2003;26:212-21.
    • (2003) J Immunother , vol.26 , pp. 212-221
    • Kruger, S.1    Schroers, R.2    Rooney, C.M.3    Gahn, B.4    Chen, S.Y.5
  • 38
    • 0032194159 scopus 로고    scopus 로고
    • Structural basis of specificity and degeneracy of T cell recognition: Pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR
    • Doherty DG, Penzotti JE, Koelle DM, et al. Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR. J Immunol 1998;161:3527-35.
    • (1998) J Immunol , vol.161 , pp. 3527-3535
    • Doherty, D.G.1    Penzotti, J.E.2    Koelle, D.M.3
  • 39
    • 0033936778 scopus 로고    scopus 로고
    • Quantitation of T-cell receptor frequencies by competitive polymerase chain reaction: Dynamics of T-cell clonotype frequencies in an expanding tumor-infiltrating lymphocyte culture
    • McKee MD, Clay TM, Diamond RA, Rosenberg SA, Nishimura MI. Quantitation of T-cell receptor frequencies by competitive polymerase chain reaction: dynamics of T-cell clonotype frequencies in an expanding tumor-infiltrating lymphocyte culture. J Immunother 2000;23:419-29.
    • (2000) J Immunother , vol.23 , pp. 419-429
    • McKee, M.D.1    Clay, T.M.2    Diamond, R.A.3    Rosenberg, S.A.4    Nishimura, M.I.5
  • 40
    • 0037236815 scopus 로고    scopus 로고
    • Regulatory T cells: Mediating compromises between host and parasite
    • Sakaguchi S. Regulatory T cells: mediating compromises between host and parasite. Nat Immunol 2003;4:10-1.
    • (2003) Nat Immunol , vol.4 , pp. 10-11
    • Sakaguchi, S.1
  • 41
    • 0035546070 scopus 로고    scopus 로고
    • CD4(+) regulatory T cells
    • Read S, Powrie F. CD4(+) regulatory T cells. Curr Opin Immunol 2001;13:644-9.
    • (2001) Curr Opin Immunol , vol.13 , pp. 644-649
    • Read, S.1    Powrie, F.2
  • 42
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004;22:531-62.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 43
    • 2542420993 scopus 로고    scopus 로고
    • In vivo instruction of suppressor commitment in naive T cells
    • Apostolou I, von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J Exp Med 2004;199:1401-8.
    • (2004) J Exp Med , vol.199 , pp. 1401-1408
    • Apostolou, I.1    Von Boehmer, H.2
  • 44
    • 2442450433 scopus 로고    scopus 로고
    • IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells
    • Vieira PL, Christensen JR, Minaee S, et al. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol 2004;172:5986-93.
    • (2004) J Immunol , vol.172 , pp. 5986-5993
    • Vieira, P.L.1    Christensen, J.R.2    Minaee, S.3
  • 45
    • 10744222813 scopus 로고    scopus 로고
    • Immunization of patients with metastatic melanoma using both class I- And class II-restricted peptides from melanoma-associated antigens
    • Phan GQ, Touloukian CE, Yang JC, et al. Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens. J Immunother 2003;26:349-56.
    • (2003) J Immunother , vol.26 , pp. 349-356
    • Phan, G.Q.1    Touloukian, C.E.2    Yang, J.C.3
  • 46
    • 0037436121 scopus 로고    scopus 로고
    • Immunology. Regulating the regulators
    • Wash DC
    • Powrie F, Maloy KJ. Immunology. Regulating the regulators. Science (Wash DC) 2003;299:1030-1.
    • (2003) Science , vol.299 , pp. 1030-1031
    • Powrie, F.1    Maloy, K.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.