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Volumn 91, Issue 2, 1998, Pages 585-594

Circulating CD8 T lymphocytes in human immunodeficiency virus-infected individuals have impaired function and downmodulate CD3ζ, the signaling chain of the T-cell receptor complex

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GRANZYME A; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

EID: 0031973577     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.2.585.585_585_594     Document Type: Article
Times cited : (158)

References (53)
  • 7
    • 0024333293 scopus 로고
    • Detection of major histocompatibility complex class I-restricted, HIV-specific cytotoxic T lymphocytes in the blood of infected hemophiliacs
    • Koup RA, Sullivan JL, Levine PH, Brettler D, Mahr A, Mazzara G, McKenzie S, Panicali D: Detection of major histocompatibility complex class I-restricted, HIV-specific cytotoxic T lymphocytes in the blood of infected hemophiliacs. Blood 73:1909, 1989
    • (1989) Blood , vol.73 , pp. 1909
    • Koup, R.A.1    Sullivan, J.L.2    Levine, P.H.3    Brettler, D.4    Mahr, A.5    Mazzara, G.6    McKenzie, S.7    Panicali, D.8
  • 8
    • 0024593160 scopus 로고
    • Human immunodeficiency virus-specific cytotoxic responses of seropositive individuals: Distinct types of effector cells mediate killing of targets expressing gag and env proteins
    • Riviere Y, Tanneau-Salvadori F, Regnault A, Lopez O, Sansonetti P, Guy B, Kieny MP, Fournel JJ, Montagnier L: Human immunodeficiency virus-specific cytotoxic responses of seropositive individuals: Distinct types of effector cells mediate killing of targets expressing gag and env proteins. J Virol 63:2270, 1989
    • (1989) J Virol , vol.63 , pp. 2270
    • Riviere, Y.1    Tanneau-Salvadori, F.2    Regnault, A.3    Lopez, O.4    Sansonetti, P.5    Guy, B.6    Kieny, M.P.7    Fournel, J.J.8    Montagnier, L.9
  • 9
    • 0026535244 scopus 로고
    • Cytotoxic T lymphocytes from HIV-1 seropositive individuals recognize immunodominant epitopes in Gp160 and reverse transcriptase
    • Lieberman J, Fabry JA, Kuo MC, Earl P, Moss B, Skolnik PR: Cytotoxic T lymphocytes from HIV-1 seropositive individuals recognize immunodominant epitopes in Gp160 and reverse transcriptase. J Immunol 148:2738, 1992
    • (1992) J Immunol , vol.148 , pp. 2738
    • Lieberman, J.1    Fabry, J.A.2    Kuo, M.C.3    Earl, P.4    Moss, B.5    Skolnik, P.R.6
  • 15
    • 0028150647 scopus 로고
    • Correlation between disease activity and T-cell CD3 zeta chain expression in a B-cell lymphoma
    • Massaia M, Attisano C, Beggiato E, Bianchi A, Piled A: Correlation between disease activity and T-cell CD3 zeta chain expression in a B-cell lymphoma. Br J Haematol 88:886, 1994
    • (1994) Br J Haematol , vol.88 , pp. 886
    • Massaia, M.1    Attisano, C.2    Beggiato, E.3    Bianchi, A.4    Piled, A.5
  • 16
    • 0029902054 scopus 로고    scopus 로고
    • T cells from patients with Hodgkin's disease have a detective T-cell receptor zeta chain expression that is reversible by T-cell stimulation with CD3 and CD28
    • Renner C, Ohnesorge S, Held G, Bauer S, Jung W, Pfitzenmeier JP, Pfreundschuh M: T cells from patients with Hodgkin's disease have a detective T-cell receptor zeta chain expression that is reversible by T-cell stimulation with CD3 and CD28. Blood 88:236, 1996
    • (1996) Blood , vol.88 , pp. 236
    • Renner, C.1    Ohnesorge, S.2    Held, G.3    Bauer, S.4    Jung, W.5    Pfitzenmeier, J.P.6    Pfreundschuh, M.7
  • 17
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss A, Littman DR: Signal transduction by lymphocyte antigen receptors. Cell 76:263, 1994
    • (1994) Cell , vol.76 , pp. 263
    • Weiss, A.1    Littman, D.R.2
  • 18
    • 0026218587 scopus 로고
    • Structure, assembly and intracellular transport of the T cell receptor for antigen
    • Exley M, Terhorst C, Wileman T: Structure, assembly and intracellular transport of the T cell receptor for antigen. Sem Immunol 3:283, 1991
    • (1991) Sem Immunol , vol.3 , pp. 283
    • Exley, M.1    Terhorst, C.2    Wileman, T.3
  • 19
    • 0028979704 scopus 로고
    • Rapid turnover of the CD3 zeta chain independent of the TCR-CD3 complex normal T cells
    • Ono S, Ohno H, Saito T: Rapid turnover of the CD3 zeta chain independent of the TCR-CD3 complex normal T cells. Immunity 2:639, 1995
    • (1995) Immunity , vol.2 , pp. 639
    • Ono, S.1    Ohno, H.2    Saito, T.3
  • 20
    • 0027122957 scopus 로고
    • 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults
    • Centers for Disease Control: 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR Morb Mortal Wkly Rep 41:1, 1993
    • (1993) MMWR Morb Mortal Wkly Rep , vol.41 , pp. 1
  • 21
    • 0030787867 scopus 로고    scopus 로고
    • Recombinant human granzyme a binds to two putative HLA-associated proteins and cleaves one of them
    • Beresford PJ, Kam C-M, Powers JC, Lieberman J: Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them. Proc Natl Acad Sci USA 94:9285, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9285
    • Beresford, P.J.1    Kam, C.-M.2    Powers, J.C.3    Lieberman, J.4
  • 23
    • 0021859627 scopus 로고
    • A novel serine protease expressed by cytotoxic T lymphocytes
    • Pasternack MS, Eisen HN: A novel serine protease expressed by cytotoxic T lymphocytes. Nature 314:743, 1985
    • (1985) Nature , vol.314 , pp. 743
    • Pasternack, M.S.1    Eisen, H.N.2
  • 24
    • 0001041396 scopus 로고
    • Isolation and biochemical and functional characterization of perform 1 from cytolytic T cell granules
    • Podack ER, Young JD-E, Cohn ZA: Isolation and biochemical and functional characterization of perform 1 from cytolytic T cell granules. Proc Natl Acad Sci USA 82:8629, 1985
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8629
    • Podack, E.R.1    Young, J.D.-E.2    Cohn, Z.A.3
  • 25
    • 0023820255 scopus 로고
    • Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation
    • Jenne DE, Tschopp J: Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation. Immunol Rev 103:53, 1988
    • (1988) Immunol Rev , vol.103 , pp. 53
    • Jenne, D.E.1    Tschopp, J.2
  • 26
    • 0022624829 scopus 로고
    • Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte
    • Gershenfeld HK, Weissman IL: Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte. Science 232:854, 1986
    • (1986) Science , vol.232 , pp. 854
    • Gershenfeld, H.K.1    Weissman, I.L.2
  • 28
    • 0022980626 scopus 로고
    • A model for the selective loss of major histocompatibility complex self-restricted T cell immune responses during the development of acquired immune deficiency syndrome (AIDS)
    • Shearer GM, Bernstein DC, Tung KS, Via CS, Redfield R, Salahuddin SZ, Gallo RC: A model for the selective loss of major histocompatibility complex self-restricted T cell immune responses during the development of acquired immune deficiency syndrome (AIDS). J Immunol 137:2514, 1986
    • (1986) J Immunol , vol.137 , pp. 2514
    • Shearer, G.M.1    Bernstein, D.C.2    Tung, K.S.3    Via, C.S.4    Redfield, R.5    Salahuddin, S.Z.6    Gallo, R.C.7
  • 29
    • 0028987175 scopus 로고
    • The role of p56lck in CD4-mediated suppression of CDS-induced early signaling events in T lymphocytes
    • Baier-Bitterlich G, Baier G, Gulbins E, Coggeshall KM, Altman A: The role of p56lck in CD4-mediated suppression of CDS-induced early signaling events in T lymphocytes. Life Sci 56:1287, 1995
    • (1995) Life Sci , vol.56 , pp. 1287
    • Baier-Bitterlich, G.1    Baier, G.2    Gulbins, E.3    Coggeshall, K.M.4    Altman, A.5
  • 30
    • 0030636724 scopus 로고    scopus 로고
    • CD4 ligands inhibit the formation of multifunctional transduction complexes involved in T cell activation
    • Jabado N, Pallier A, Le Deist F, Bernard F, Fischer A, Hivroz C: CD4 ligands inhibit the formation of multifunctional transduction complexes involved in T cell activation. J Immunol 158:94, 1997
    • (1997) J Immunol , vol.158 , pp. 94
    • Jabado, N.1    Pallier, A.2    Le Deist, F.3    Bernard, F.4    Fischer, A.5    Hivroz, C.6
  • 31
    • 0031091744 scopus 로고    scopus 로고
    • Sequestration of p56(lck) by gp 120, a model for TCR desensitization
    • Goldman F, Crabtree J, Hollenback C, Koretzky G: Sequestration of p56(lck) by gp 120, a model for TCR desensitization. J Immunol 158:2017, 1997
    • (1997) J Immunol , vol.158 , pp. 2017
    • Goldman, F.1    Crabtree, J.2    Hollenback, C.3    Koretzky, G.4
  • 32
    • 0031575530 scopus 로고    scopus 로고
    • Binding of HIV-1 to its receptor induces tyrosine phosphorylation of several CD4-associated proteins, including the phosphatidylinositol 3-kinase
    • Briand G, Barbeau B, Tremblay M: Binding of HIV-1 to its receptor induces tyrosine phosphorylation of several CD4-associated proteins, including the phosphatidylinositol 3-kinase. Virology 228: 171,1997
    • (1997) Virology , vol.228 , pp. 171
    • Briand, G.1    Barbeau, B.2    Tremblay, M.3
  • 33
    • 0031054716 scopus 로고    scopus 로고
    • HIV glycoprotein gp120 inhibits TCR-CD3-mediated activation of fyn and lck
    • Morio T, Chatila T, Geha RS: HIV glycoprotein gp120 inhibits TCR-CD3-mediated activation of fyn and lck. Int Immunol 9:53, 1997
    • (1997) Int Immunol , vol.9 , pp. 53
    • Morio, T.1    Chatila, T.2    Geha, R.S.3
  • 34
    • 0028180868 scopus 로고
    • Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
    • Aiken C, Konner J, Landau NR, Lenburg ME, Trono D: Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76:853, 1994
    • (1994) Cell , vol.76 , pp. 853
    • Aiken, C.1    Konner, J.2    Landau, N.R.3    Lenburg, M.E.4    Trono, D.5
  • 35
    • 0028485232 scopus 로고
    • HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization
    • Baur AS, Sawai ET, Dazin P, Fantl WJ, Cheng-Mayer C, Peterlin BM: HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization. Immunity 1:373, 1994
    • (1994) Immunity , vol.1 , pp. 373
    • Baur, A.S.1    Sawai, E.T.2    Dazin, P.3    Fantl, W.J.4    Cheng-Mayer, C.5    Peterlin, B.M.6
  • 36
    • 0027997802 scopus 로고
    • + T cells inhibits the binding activity of NF-AT, NF-kappa B and AP-1, three nuclear factors regulating interleukin-2 gene enhancer activity
    • + T cells inhibits the binding activity of NF-AT, NF-kappa B and AP-1, three nuclear factors regulating interleukin-2 gene enhancer activity. Eur J Immunol 24:2646, 1994
    • (1994) Eur J Immunol , vol.24 , pp. 2646
    • Jabado, N.1    Le Deist, F.2    Fisher, A.3    Hivroz, C.4
  • 38
    • 0031039979 scopus 로고    scopus 로고
    • Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
    • Iafrate AJ, Bronson S, Skowronski J: Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling. EMBO J 16:673, 1997
    • (1997) EMBO J , vol.16 , pp. 673
    • Iafrate, A.J.1    Bronson, S.2    Skowronski, J.3
  • 39
  • 40
    • 0027275931 scopus 로고
    • Mechanism of HIV-1 Tat induced inhibition of antigen-specific T cell responsiveness
    • Subramanyam M, Gutheil WG, Bachovchin WW, Huber BT: Mechanism of HIV-1 Tat induced inhibition of antigen-specific T cell responsiveness. J Immunol 150:2544, 1993
    • (1993) J Immunol , vol.150 , pp. 2544
    • Subramanyam, M.1    Gutheil, W.G.2    Bachovchin, W.W.3    Huber, B.T.4
  • 41
    • 0028924021 scopus 로고
    • Human immunodeficiency viras Tat induces functional unresponsiveness in T cells
    • Chirmule N, Than S, Khan SA, Pahwa S: Human immunodeficiency viras Tat induces functional unresponsiveness in T cells: J Virol 69:492, 1995
    • (1995) J Virol , vol.69 , pp. 492
    • Chirmule, N.1    Than, S.2    Khan, S.A.3    Pahwa, S.4
  • 42
    • 0027613369 scopus 로고
    • Direct and indirect mechanisms mediating apoptosis during HIV infection: Contribution to in vivo CD4 T cell depletion
    • Gougeon ML, Laurent-Crawford AG, Hovanessian AG, Montagnier L: Direct and indirect mechanisms mediating apoptosis during HIV infection: Contribution to in vivo CD4 T cell depletion. Semin Immunol 5:187, 1993
    • (1993) Semin Immunol , vol.5 , pp. 187
    • Gougeon, M.L.1    Laurent-Crawford, A.G.2    Hovanessian, A.G.3    Montagnier, L.4
  • 45
    • 0031026259 scopus 로고    scopus 로고
    • Transfer of the interleukin-2 gene into human cancer cells induces specific antitumor recognition and restores the expression of CD3/T-cell receptor associated signal transduction molecules
    • Guarini A, Riera L, Cignetti A, Montacchini L, Massaia M, Foa R: Transfer of the interleukin-2 gene into human cancer cells induces specific antitumor recognition and restores the expression of CD3/T-cell receptor associated signal transduction molecules. Blood 89:212, 1997
    • (1997) Blood , vol.89 , pp. 212
    • Guarini, A.1    Riera, L.2    Cignetti, A.3    Montacchini, L.4    Massaia, M.5    Foa, R.6
  • 46
    • 0028965830 scopus 로고
    • Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex
    • Aoe T, Okamoto Y, Saito T: Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex. J Exp Med 181:1881, 1995
    • (1995) J Exp Med , vol.181 , pp. 1881
    • Aoe, T.1    Okamoto, Y.2    Saito, T.3
  • 47
    • 0029841427 scopus 로고    scopus 로고
    • Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses
    • Otsuji M, Kimura Y, Aoe T, Okamoto Y, Saito T: Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses. Proc Natl Acad Sci USA 93:13119, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13119
    • Otsuji, M.1    Kimura, Y.2    Aoe, T.3    Okamoto, Y.4    Saito, T.5
  • 50
    • 0028198720 scopus 로고
    • Therapeutic reconstitution of human viral immunity by adoptive transfer of cytotoxic T lymphocyte clones
    • Riddell SR, Greenberg PD: Therapeutic reconstitution of human viral immunity by adoptive transfer of cytotoxic T lymphocyte clones. CurrTop Microbiol Immunol 189:9, 1994
    • (1994) CurrTop Microbiol Immunol , vol.189 , pp. 9
    • Riddell, S.R.1    Greenberg, P.D.2
  • 51
    • 0030854210 scopus 로고    scopus 로고
    • Safety of autologous, ex vivo-expanded HIV-specific cytotoxic T lymphocyte infusion in HIV-infected patients
    • Lieberman J, Skolnik PR, Parkerson GR, Fabry JA, Landry B, Bethel J, Kagan J, DATRI 006 Study Team: Safety of autologous, ex vivo-expanded HIV-specific cytotoxic T lymphocyte infusion in HIV-infected patients. Blood 90:2196, 1997
    • (1997) Blood , vol.90 , pp. 2196
    • Lieberman, J.1    Skolnik, P.R.2    Parkerson, G.R.3    Fabry, J.A.4    Landry, B.5    Bethel, J.6    Kagan, J.7
  • 53
    • 0029811148 scopus 로고    scopus 로고
    • Rational interleukin 2 therapy for HIV positive individuals: Daily low doses enhance immune function without toxicity
    • Jacobson EL, Pilaro F, Smith KA: Rational interleukin 2 therapy for HIV positive individuals: Daily low doses enhance immune function without toxicity. Proc Natl Acad Sci USA 93:10405, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10405
    • Jacobson, E.L.1    Pilaro, F.2    Smith, K.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.