HIV-specific CD8+ T cells produce antiviral cytokines but are impaired in cytolytic function

Journal of Experimental Medicine

Volumn 192, Issue 1, 2000, Pages 63-75

  Appay, Victor ^a   Nixon, Douglas F ^b   Donahoe, Sean M ^b   Gillespie, Geraldine M A ^a   Dong, Tao ^a   King, Abigail ^a   Ogg, Graham S ^a   Spiegel, Hans M L ^b   Conlon, Christopher ^a   Spina, Celsa A ^c,d   Havlir, Diane V ^c   Richman, Douglas D ^c,d   Waters, Anele ^e   Easterbrook, Philippa ^e   McMichael, Andrew J ^a   Rowland Jones, Sarah L ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e Caldecot Centre   (United Kingdom)

Author keywords

Cytokines; Cytotoxic T lymphocytes; HIV; Perforin; Tetramers

Indexed keywords

CHEMOKINE; CYTOKINE; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PERFORIN; TETRAMER; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS REPLICATION;

CD8-POSITIVE T-LYMPHOCYTES; CLONE CELLS; CYTOKINES; CYTOMEGALOVIRUS; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV; HIV INFECTIONS; HIV SERONEGATIVITY; HUMANS; INTERFERON TYPE II; MACROPHAGE INFLAMMATORY PROTEIN-1; REFERENCE VALUES; T-LYMPHOCYTES, CYTOTOXIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034600786     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.1.63     Document Type: Article

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