4-Hydroxy-2(E)-nonenal inhibits CNS mitochondrial respiration at multiple sites

Journal of Neurochemistry

Volumn 72, Issue 4, 1999, Pages 1617-1624

  Picklo, Matthew J ^a,b   Amarnath, Venkataraman ^a   McIntyre, J Oliver ^a   Graham, Doyle G ^a   Montine, Thomas J ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

4 Hydroxy 2(E) nonenal; Adduct; Complex III; Mitochondria; Neurodegeneration; Peroxidation

Indexed keywords

4 HYDROXYNONENAL;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN MITOCHONDRION; COMPLEX FORMATION; DEGENERATIVE DISEASE; ELECTRON TRANSPORT; LIPID PEROXIDATION; LIPOPHILICITY; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ALDEHYDES; ANIMALS; CELL RESPIRATION; CYSTEINE PROTEINASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX III; LIPID PEROXIDATION; MALE; MITOCHONDRIA; MULTIENZYME COMPLEXES; NAD(P)H DEHYDROGENASE (QUINONE); NERVE DEGENERATION; NEURONS; OXIDOREDUCTASES; RATS; RATS, SPRAGUE-DAWLEY; SUCCINATE DEHYDROGENASE; SWINE;

ANIMALIA; SUIDAE;

EID: 0033034787     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.721617.x     Document Type: Article

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