-
1
-
-
0031762799
-
Ethanol inhibits hepatocyte proliferation in insulin receptor substrate 1 transgenic mice
-
Mohr L, Tanaka S, Wands JR. Ethanol inhibits hepatocyte proliferation in insulin receptor substrate 1 transgenic mice. Gastroenterology 1998;115:1558-1565.
-
(1998)
Gastroenterology
, vol.115
, pp. 1558-1565
-
-
Mohr, L.1
Tanaka, S.2
Wands, J.R.3
-
2
-
-
0028004937
-
Ethanol impairs insulin receptor substrate-1 mediated signal transduction during rat liver regeneration
-
Sasaki Y, Wands JR. Ethanol impairs insulin receptor substrate-1 mediated signal transduction during rat liver regeneration. Biochem Biophys Res Commun 1994;199:403-409.
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 403-409
-
-
Sasaki, Y.1
Wands, J.R.2
-
3
-
-
0035142767
-
Inhibition of insulin-like growth factor-1 receptor and IRS-2 signaling by ethanol in SH-SY5Y neuroblastoma cells
-
Seiler AE, Ross BN, Rubin R. Inhibition of insulin-like growth factor-1 receptor and IRS-2 signaling by ethanol in SH-SY5Y neuroblastoma cells. J Neurochem 2001;76:573-581.
-
(2001)
J Neurochem
, vol.76
, pp. 573-581
-
-
Seiler, A.E.1
Ross, B.N.2
Rubin, R.3
-
4
-
-
0029084530
-
Ethanol inhibits insulin receptor substrate-1 tyrosine phosphorylation and insulin-stimulated neuronal thread protein gene expression
-
Xu YY, Bhavani K, Wands JR, de la Monte SM. Ethanol inhibits insulin receptor substrate-1 tyrosine phosphorylation and insulin-stimulated neuronal thread protein gene expression. Biochem J 1995;310:125-132.
-
(1995)
Biochem J
, vol.310
, pp. 125-132
-
-
Xu, Y.Y.1
Bhavani, K.2
Wands, J.R.3
De la Monte, S.M.4
-
6
-
-
0025220148
-
Intrinsic kinase activity of the insulin receptor
-
O'Hare T, Pilch PF. Intrinsic kinase activity of the insulin receptor. Int J Biochem 1990;22:315-324.
-
(1990)
Int J Biochem
, vol.22
, pp. 315-324
-
-
O'Hare, T.1
Pilch, P.F.2
-
7
-
-
0021985413
-
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
-
Ullrich A, Bell JR, Chen EY, Herrera R, Petruzzelli LM, Dull TJ, Gray A, et al. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature 1985;313:756-761.
-
(1985)
Nature
, vol.313
, pp. 756-761
-
-
Ullrich, A.1
Bell, J.R.2
Chen, E.Y.3
Herrera, R.4
Petruzzelli, L.M.5
Dull, T.J.6
Gray, A.7
-
8
-
-
0025813375
-
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
-
Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, Cahill DA, et al. Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 1991;352:73-77.
-
(1991)
Nature
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
Cahill, D.A.7
-
9
-
-
0027437376
-
Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1
-
Sun XJ, Crimmins DL, Myers MJ, Miralpeix M, White MF. Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1. Mol Cell Biol 1993;13:7418-7428.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7418-7428
-
-
Sun, X.J.1
Crimmins, D.L.2
Myers, M.J.3
Miralpeix, M.4
White, M.F.5
-
10
-
-
0026489451
-
IRS-1 activates phosphatidylinositol 3′-kinase by associating with src homology 2 domains of p85
-
Myers MG, Backer JM, Sun XJ, Shoelson S, Hu P, Schlessinger J, Yoakim M, et al. IRS-1 activates phosphatidylinositol 3′-kinase by associating with src homology 2 domains of p85. Proc Natl Acad Sci U S A 1992;89:10350-10354.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10350-10354
-
-
Myers, M.G.1
Backer, J.M.2
Sun, X.J.3
Shoelson, S.4
Hu, P.5
Schlessinger, J.6
Yoakim, M.7
-
11
-
-
0028825920
-
Compensatory alterations for insulin signal transduction and glucose transport in insulin-resistant diabetes
-
Bonini JA, Colca JR, Dailey C, White M, Hofmann C. Compensatory alterations for insulin signal transduction and glucose transport in insulin-resistant diabetes. Am J Physiol 1995;269:E759-E765.
-
(1995)
Am J Physiol
, vol.269
-
-
Bonini, J.A.1
Colca, J.R.2
Dailey, C.3
White, M.4
Hofmann, C.5
-
12
-
-
0028336998
-
Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C
-
Kuhne MR, Zhao Z, Rowles J, Lavan BE, Shen SH, Fischer EH, Lienhard GE. Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C. J Biol Chem 1994;269:15833-15837.
-
(1994)
J Biol Chem
, vol.269
, pp. 15833-15837
-
-
Kuhne, M.R.1
Zhao, Z.2
Rowles, J.3
Lavan, B.E.4
Shen, S.H.5
Fischer, E.H.6
Lienhard, G.E.7
-
13
-
-
0026660653
-
Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation
-
Backer JM, Myers MJ, Shoelson SE, Chin DJ, Sun XJ, Miralpeix M, Hu P, et al. Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation. EMBO J 1992;11:3469-3479.
-
(1992)
EMBO J
, vol.11
, pp. 3469-3479
-
-
Backer, J.M.1
Myers, M.J.2
Shoelson, S.E.3
Chin, D.J.4
Sun, X.J.5
Miralpeix, M.6
Hu, P.7
-
14
-
-
0031916439
-
The Ras/RacI/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocyres
-
Auer KL, Contessa J, Brenz-Verca S, Pirola L, Rusconi S, Cooper G, Abo A, et al. The Ras/RacI/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocyres. Mol Biol Cell 1986;9:561-573.
-
(1986)
Mol Biol Cell
, vol.9
, pp. 561-573
-
-
Auer, K.L.1
Contessa, J.2
Brenz-Verca, S.3
Pirola, L.4
Rusconi, S.5
Cooper, G.6
Abo, A.7
-
15
-
-
0027292553
-
Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes
-
Baltensperger K, Kozma LM, Cherniack AD, Klarlund JK, Chawla A, Banerjee U, Czech MP. Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes. Science 1993;260:1950-1952.
-
(1993)
Science
, vol.260
, pp. 1950-1952
-
-
Baltensperger, K.1
Kozma, L.M.2
Cherniack, A.D.3
Klarlund, J.K.4
Chawla, A.5
Banerjee, U.6
Czech, M.P.7
-
16
-
-
0027182367
-
The function of GRB2 in linking the insulin receptor to Ras signaling pathways
-
Skolnik EY, Batzer A, Li N, Lee CH, Lowenstein E, Mohammadi M, Margolis B, et al. The function of GRB2 in linking the insulin receptor to Ras signaling pathways. Science 1993;260:1953-1955.
-
(1993)
Science
, vol.260
, pp. 1953-1955
-
-
Skolnik, E.Y.1
Batzer, A.2
Li, N.3
Lee, C.H.4
Lowenstein, E.5
Mohammadi, M.6
Margolis, B.7
-
17
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 1995;376599-376602.
-
(1995)
Nature
, pp. 376599-376602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
18
-
-
0032189381
-
Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
-
Coffer PJ, Jin J, Woodgett JR. Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J 1998;335:1-13.
-
(1998)
Biochem J
, vol.335
, pp. 1-13
-
-
Coffer, P.J.1
Jin, J.2
Woodgett, J.R.3
-
20
-
-
0019797712
-
Blood ethanol levels in sober alcohol users seen in an emergency room
-
Urso T, Gavaler JS, Van Thiel DH. Blood ethanol levels in sober alcohol users seen in an emergency room. Life Sci 1981;28:1053-1056.
-
(1981)
Life Sci
, vol.28
, pp. 1053-1056
-
-
Urso, T.1
Gavaler, J.S.2
Van Thiel, D.H.3
-
21
-
-
0004265596
-
-
New York: John Wiley & Sons
-
Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K. Current Protocols in Molecular Biology. New York: John Wiley & Sons, 2002.
-
(2002)
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
22
-
-
0017101039
-
Preparation of isolated rat liver cells
-
Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1976;13:29-83.
-
(1976)
Methods Cell Biol
, vol.13
, pp. 29-83
-
-
Seglen, P.O.1
-
23
-
-
0032508505
-
Activation of caspase-1 in the nucleus requires nuclear translocation of pro-caspase-1 mediated by its prodomain
-
Mao PL, Jiang Y, Wee BY, Porter AG. Activation of caspase-1 in the nucleus requires nuclear translocation of pro-caspase-1 mediated by its prodomain. J Biol Chem 1998;273:23621-23624.
-
(1998)
J Biol Chem
, vol.273
, pp. 23621-23624
-
-
Mao, P.L.1
Jiang, Y.2
Wee, B.Y.3
Porter, A.G.4
-
24
-
-
0036224165
-
Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-α or EGF, augments pancreatic β-cell proliferation
-
Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-α or EGF, augments pancreatic β-cell proliferation. Diabetes 2002;51:966-976.
-
(2002)
Diabetes
, vol.51
, pp. 966-976
-
-
Lingohr, M.K.1
Dickson, L.M.2
McCuaig, J.F.3
Hugl, S.R.4
Twardzik, D.R.5
Rhodes, C.J.6
-
25
-
-
0037040936
-
Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway
-
Xiao H, Yin T, Wang XY, Uchida T, Chung J, White MF, Yang YC. Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway. J Biol Chem 2002;277:8091-8098.
-
(2002)
J Biol Chem
, vol.277
, pp. 8091-8098
-
-
Xiao, H.1
Yin, T.2
Wang, X.Y.3
Uchida, T.4
Chung, J.5
White, M.F.6
Yang, Y.C.7
-
26
-
-
0035605844
-
TPIP: A novel phosphoinositide 3-phosphatase
-
Walker SM, Downes CP, Leslie NR. TPIP: a novel phosphoinositide 3-phosphatase. Biochem J 2001;360:277-283.
-
(2001)
Biochem J
, vol.360
, pp. 277-283
-
-
Walker, S.M.1
Downes, C.P.2
Leslie, N.R.3
-
27
-
-
0035847102
-
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
-
Torres J, Pulido R. The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation. J Biol Chem 2001;276:993-998.
-
(2001)
J Biol Chem
, vol.276
, pp. 993-998
-
-
Torres, J.1
Pulido, R.2
-
28
-
-
0033946740
-
Phosphorylation of the PTEN tail regulates protein stability and function
-
Vazquez F, Ramaswamy S, Nakamura N, Sellers WR. Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol 2000;20:5010-5018.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5010-5018
-
-
Vazquez, F.1
Ramaswamy, S.2
Nakamura, N.3
Sellers, W.R.4
-
29
-
-
18344380088
-
p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas
-
Singh B, Reddy PG, Goberdhan A, Walsh C, Dao S, Ngai I, Chou TC, et al. p53 Regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas. Genes Dev 2003;16:984-993.
-
(2003)
Genes Dev
, vol.16
, pp. 984-993
-
-
Singh, B.1
Reddy, P.G.2
Goberdhan, A.3
Walsh, C.4
Dao, S.5
Ngai, I.6
Chou, T.C.7
-
30
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999;96:857-868.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
-
31
-
-
0036325163
-
Decreased akt activity is associated with activation of forkhead transcription factor after transient forebrain ischemia in gerbil hippocampus
-
Kawano T, Morioka M, Yano S, Hamada J, Ushio Y, Miyamoto E, Fukunaga K. Decreased akt activity is associated with activation of forkhead transcription factor after transient forebrain ischemia in gerbil hippocampus. J Cereb Blood Flow Metab 2002;22:926-934.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 926-934
-
-
Kawano, T.1
Morioka, M.2
Yano, S.3
Hamada, J.4
Ushio, Y.5
Miyamoto, E.6
Fukunaga, K.7
-
32
-
-
0031743648
-
p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
Muller M, Wilder S, Bannasch D, Israeli D, Lehlbach K, Li-Weber M, Friedman SL, et al. p53 Activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 1998;188:2033-2045.
-
(1998)
J Exp Med
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
Israeli, D.4
Lehlbach, K.5
Li-Weber, M.6
Friedman, S.L.7
-
33
-
-
0028844784
-
Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells
-
Tamura T, Aoyama N, Saya H, Haga H, Futami S, Miyamoto M, Koh T, et al. Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells. Oncogene 1995;11:1939-1946.
-
(1995)
Oncogene
, vol.11
, pp. 1939-1946
-
-
Tamura, T.1
Aoyama, N.2
Saya, H.3
Haga, H.4
Futami, S.5
Miyamoto, M.6
Koh, T.7
-
34
-
-
0029003501
-
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
-
Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, et al. Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 1995;15:3032-3040.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3032-3040
-
-
Owen-Schaub, L.B.1
Zhang, W.2
Cusack, J.C.3
Angelo, L.S.4
Santee, S.M.5
Fujiwara, T.6
Roth, J.A.7
-
35
-
-
0034731449
-
Rapid activation of protein kinase B/Akt has a key role in antiapoptotic signaling during liver regeneration
-
Hong F, Nguyen VA, Shen X, Kunos G, Gao B. Rapid activation of protein kinase B/Akt has a key role in antiapoptotic signaling during liver regeneration. Biochem Biophys Res Commun 2002;279:974-979.
-
(2002)
Biochem Biophys Res Commun
, vol.279
, pp. 974-979
-
-
Hong, F.1
Nguyen, V.A.2
Shen, X.3
Kunos, G.4
Gao, B.5
-
36
-
-
0031034574
-
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
-
Kulik G, Klippel A, Weber MJ. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol Cell Biol 1997;17:1595-1606.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1595-1606
-
-
Kulik, G.1
Klippel, A.2
Weber, M.J.3
-
37
-
-
0035967897
-
Regulation of GSK-3: A cellular multiprocessor
-
Harwood AJ. Regulation of GSK-3: a cellular multiprocessor. Cell 2001;105:821-824.
-
(2001)
Cell
, vol.105
, pp. 821-824
-
-
Harwood, A.J.1
-
38
-
-
0034717141
-
Inhibition ofglycogen-synthase kinase 3 stimulates glycogen synthase and glucose transport by distinct mechanisms in 3T3-L1 adipocytes
-
Orena SJ, Torchia AJ, Garofalo RS. Inhibition ofglycogen-synthase kinase 3 stimulates glycogen synthase and glucose transport by distinct mechanisms in 3T3-L1 adipocytes. J Biol Chem 2000;275:15765-15772.
-
(2000)
J Biol Chem
, vol.275
, pp. 15765-15772
-
-
Orena, S.J.1
Torchia, A.J.2
Garofalo, R.S.3
-
39
-
-
0032493729
-
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
-
Pap M, Cooper GM. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway. J Biol Chem 1998;273:19929-19932.
-
(1998)
J Biol Chem
, vol.273
, pp. 19929-19932
-
-
Pap, M.1
Cooper, G.M.2
-
40
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997;91:231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
41
-
-
0035047712
-
Caspase cleavage enhances the apoptosis-inducing effects of BAD
-
Condorelli F, Salomoni P, Cotteret S, Cesi V, Srinivasula SM, Alnemri ES, Calabretta B. Caspase cleavage enhances the apoptosis-inducing effects of BAD. Mol Cell Biol 2001;21:3025-3036.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3025-3036
-
-
Condorelli, F.1
Salomoni, P.2
Cotteret, S.3
Cesi, V.4
Srinivasula, S.M.5
Alnemri, E.S.6
Calabretta, B.7
-
42
-
-
0032808154
-
Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria
-
Kennedy SG, Kandel ES, Cross TK, Hay N. Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria. Mol Cell Biol 1999;19:5800-5810.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5800-5810
-
-
Kennedy, S.G.1
Kandel, E.S.2
Cross, T.K.3
Hay, N.4
-
43
-
-
0035875098
-
Crystal structure of glycogen synthase kinase 3 β: Structural basis for phosphate-primed substrate specificity and autoinhibition
-
Dajani R, Fraser E, Roe SM, Young N, Good V, Dale TC, Pearl LH. Crystal structure of glycogen synthase kinase 3 β: structural basis for phosphate-primed substrate specificity and autoinhibition. Cell 2001;105:721-732.
-
(2001)
Cell
, vol.105
, pp. 721-732
-
-
Dajani, R.1
Fraser, E.2
Roe, S.M.3
Young, N.4
Good, V.5
Dale, T.C.6
Pearl, L.H.7
-
44
-
-
0032557646
-
Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB
-
van Weeren PC, de Bruyn KM, de Vries-Smits AM, van Lint J, Burgering BM. Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB. J Biol Chem 1998;273:13150-13156.
-
(1998)
J Biol Chem
, vol.273
, pp. 13150-13156
-
-
Van Weeren, P.C.1
De Bruyn, K.M.2
De Vries-Smits, A.M.3
Van Lint, J.4
Burgering, B.M.5
-
46
-
-
0034681264
-
The multiple roles of PTEN in tumor suppression
-
Di Cristofano A, Pandolfi PP. The multiple roles of PTEN in tumor suppression. Cell 2000;100:387-390.
-
(2000)
Cell
, vol.100
, pp. 387-390
-
-
Di Cristofano, A.1
Pandolfi, P.P.2
-
47
-
-
0032898096
-
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies
-
Dahia PL, Aguiar RC, Alberta J, Kum JB, Caron S, Sill H, Marsh DJ, et al. PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies. Hum Mol Genet 1999;8:185-193.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 185-193
-
-
Dahia, P.L.1
Aguiar, R.C.2
Alberta, J.3
Kum, J.B.4
Caron, S.5
Sill, H.6
Marsh, D.J.7
-
48
-
-
0033615538
-
Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association
-
Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, Shi Y, Dixon JE, et al. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 1999;99:323-334.
-
(1999)
Cell
, vol.99
, pp. 323-334
-
-
Lee, J.O.1
Yang, H.2
Georgescu, M.M.3
Di Cristofano, A.4
Maehama, T.5
Shi, Y.6
Dixon, J.E.7
-
49
-
-
0032904432
-
PTEN: A tumour suppressor that functions as a phospholipid phosphatase
-
Maehama T, Dixon JE. PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol 1999;9:125-128.
-
(1999)
Trends Cell Biol
, vol.9
, pp. 125-128
-
-
Maehama, T.1
Dixon, J.E.2
-
50
-
-
0032431032
-
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
-
Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL. The PTEN/ MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 1998;95:15587-15591.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15587-15591
-
-
Wu, X.1
Senechal, K.2
Neshat, M.S.3
Whang, Y.E.4
Sawyers, C.L.5
-
51
-
-
0036094861
-
Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN
-
Huang J, Kontos CD. Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN, Arterioscler Thromb Vasc Biol 2002;22:745-751.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 745-751
-
-
Huang, J.1
Kontos, C.D.2
-
52
-
-
0034521338
-
Forkhead transcription factors are targets of signalling by the proto-oncogene PKB (C-AKT)
-
Kops GJ, Burgering BM. Forkhead transcription factors are targets of signalling by the proto-oncogene PKB (C-AKT). J Anat 2002;197:571-574.
-
(2002)
J Anat
, vol.197
, pp. 571-574
-
-
Kops, G.J.1
Burgering, B.M.2
-
53
-
-
0036172127
-
Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload
-
Badorff C, Ruetten H, Mueller S, Stahmer M, Gehring D, Jung F, Ihling C, et al. Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload. J Clin Invest 2002;109:373-381.
-
(2002)
J Clin Invest
, vol.109
, pp. 373-381
-
-
Badorff, C.1
Ruetten, H.2
Mueller, S.3
Stahmer, M.4
Gehring, D.5
Jung, F.6
Ihling, C.7
-
54
-
-
0033772549
-
Ethanol exposure enhances apoptosis within the testes
-
Zhu Q, Meisinger J, Emanuele NV, Emanuele MA, LaPaglia N, Van Thiel DH. Ethanol exposure enhances apoptosis within the testes. Alcohol Clin Exp Res 2002;24:1550-1556.
-
(2002)
Alcohol Clin Exp Res
, vol.24
, pp. 1550-1556
-
-
Zhu, Q.1
Meisinger, J.2
Emanuele, N.V.3
Emanuele, M.A.4
LaPaglia, N.5
Van Thiel, D.H.6
-
55
-
-
0032990245
-
An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice
-
Mansouri A, Gaou I, De Kerguenec C, Amsellem S, Haouzi D, Berson A, Moreau A, et al. An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice. Gastroenterology 1999;117:181-190.
-
(1999)
Gastroenterology
, vol.117
, pp. 181-190
-
-
Mansouri, A.1
Gaou, I.2
De Kerguenec, C.3
Amsellem, S.4
Haouzi, D.5
Berson, A.6
Moreau, A.7
-
56
-
-
0034128363
-
Partial rescue of ethanol-induced neuronal apoptosis by growth factor activation of phosphoinositol-3-kinase
-
de la Monte SM, Ganju N, Banerjee K, Brown NV, Luong T, Wands JR. Partial rescue of ethanol-induced neuronal apoptosis by growth factor activation of phosphoinositol-3-kinase. Alcohol Clin Exp Res 2000;24:716-726.
-
(2000)
Alcohol Clin Exp Res
, vol.24
, pp. 716-726
-
-
De la Monte, S.M.1
Ganju, N.2
Banerjee, K.3
Brown, N.V.4
Luong, T.5
Wands, J.R.6
-
57
-
-
0029121497
-
Acute ethanol and selected growth suppressor transcripts in regenerating rat liver
-
Lumpkin CK Jr, Moore TL, Tarpley MD, Taylor JM, Badger TM, McClung JK. Acute ethanol and selected growth suppressor transcripts in regenerating rat liver. Alcohol 1995;12:357-362.
-
(1995)
Alcohol
, vol.12
, pp. 357-362
-
-
Lumpkin C.K., Jr.1
Moore, T.L.2
Tarpley, M.D.3
Taylor, J.M.4
Badger, T.M.5
McClung, J.K.6
-
58
-
-
0033316264
-
Involvement of the Fas/Fas ligand system in p53-mediated granulosa cell apoptosis during follicular development and atresia
-
Kim JM, Yoon YD, Tsang BK. Involvement of the Fas/Fas ligand system in p53-mediated granulosa cell apoptosis during follicular development and atresia. Endocrinology 1999;140:2307-2317.
-
(1999)
Endocrinology
, vol.140
, pp. 2307-2317
-
-
Kim, J.M.1
Yoon, Y.D.2
Tsang, B.K.3
|