SCOPUS 정보 검색 플랫폼

Current Opinion in Biotechnology

Volumn 12, Issue 6, 2001, Pages 622-625

Functional genomics and target validation approaches using antisense oligonucleotide technology

(1) Dean, Nicholas M a

a ISIS PHARMACEUTICALS (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; NEW DRUG; RIBONUCLEASE;

BIOINFORMATICS; BIOTECHNOLOGY; CELL; DRUG INDUSTRY; DRUG TARGETING; GENE CASSETTE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENE TARGETING; GENETIC DISORDER; GENETIC MANIPULATION; GENOMICS; IN VIVO STUDY; METHODOLOGY; NONHUMAN; PHENOTYPE; POLYADENYLATION; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; RNA SPLICING; SIGNAL TRANSDUCTION; VALIDATION PROCESS;

EID: 0035709416 PISSN: 09581669 EISSN: None Source Type: Journal
DOI: 10.1016/S0958-1669(01)00270-1 Document Type: Review

Times cited : (75)

References (33)

1
- 0031304155
- The role of innovation in drug development
- (1997) Nat Biotechnol , vol.15 , pp. 1318-1319
- Drews, J.¹ Ryser, S.²

2
- 0034909257
- Drug discovery - An operating model for a new era
- (2001) Nat Biotechnol , vol.19 , pp. 727-730
- Myers, S.¹ Baker, A.²

3
- 2042437650
- Initial sequencing and analysis of the human genome
- (2001) Nature , vol.409 , pp. 860-921

4
- 0035895505
- The sequence of the human genome
- (2001) Science , vol.291 , pp. 1304-1351
- Venter, J.C.¹ Adams, M.D.² Myers, E.W.³ Li, P.W.⁴ Mural, R.J.⁵ Sutton, G.G.⁶ Smith, H.O.⁷ Yandell, M.⁸ Evans, C.A.⁹ Holt, R.A.¹⁰

5
- 0035943403
- A comparison of the Celera and Ensembl predicted gene sets reveals little overlap in novel genes
- (2001) Cell , vol.106 , pp. 413-415
- Hogenesch, J.¹ Ching, K.² Batalov, S.³ Su, A.⁴ Walker, J.⁵ Zhou, Y.⁶ Kay, S.⁷ Schultz, P.⁸ Cooke, M.⁹

6
- 0034680102
- Molecular portraits of human breast tumours
- (2000) Nature , vol.406 , pp. 747-752
- Perou, C.M.¹ Sorlie, T.² Eisen, M.B.³ Van de Rijn, M.⁴ Jeffrey, S.S.⁵ Rees, C.A.⁶ Pollack, J.R.⁷ Ross, D.T.⁸ Johnsen, H.⁹ Akslen, L.A.¹⁰

7
- 0034088857
- A gene expression database for the molecular pharmacology of cancer
- (2000) Nat Genet , vol.24 , pp. 236-244
- Scherf, U.¹ Ross, D.T.² Waltham, M.³ Smith, L.H.⁴ Lee, J.K.⁵ Tanabe, L.⁶ Kohn, K.W.⁷ Reinhold, W.C.⁸ Myers, T.G.⁹ Andrews, D.T.¹⁰

8
- 0033231026
- A public database for gene expression in human cancers
- (1999) Cancer Res , vol.59 , pp. 5403-5407
- Lal, A.¹ Lash, A.E.² Altschul, S.F.³ Velculescu, V.⁴ Zhang, L.⁵ McLendon, R.E.⁶ Marra, M.A.⁷ Prange, C.⁸ Morin, P.J.⁹ Polyak, K.¹⁰

9
- 0035810997
- Recursive partitioning for tumor classification with gene expression microarray data
- (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6730-6735
- Zhang, H.¹ Yu, C.-Y.² Singer, B.³ Xiong, M.⁴

10
- 0034625235
- The impact of comparative genomics on our understanding of evolution
- (2000) Cell , vol.101 , pp. 573-576
- Koonin, E.V.¹ Aravind, L.² Kondrashov, A.S.³

11
- 0034660322
- Protein function in the post-genomic era
- (2000) Nature , vol.405 , pp. 823-826
- Eisenberg, D.¹ Marcotte, E.M.² Xenarios, I.³ Yeates, T.O.⁴

12
- 0035860545
- Pathway databases: A case study in computational symbolic theories
- (2001) Science , vol.293 , pp. 2040-2044
- Karp, P.D.¹

13
- 0035805255
- Integrated genomic and proteomic analyses of a systematically perturbed metabolic network
- (2001) Science , vol.292 , pp. 929-934
- Ideker, T.¹ Thorsson, V.² Ranish, J.A.³ Christmas, R.⁴ Buhler, J.⁵ Eng, J.K.⁶ Bumgarner, R.⁷ Goodlett, D.R.⁸ Aebersold, R.⁹ Hood, L.¹⁰

14
- 0034659898
- Genomics, gene expression and DNA arrays
- (2000) Nature , vol.405 , pp. 827-836
- Lockhart, D.J.¹ Winzeler, E.A.²

15
- 0034659815
- Proteomics to study genes and genomes
- (2000) Nature , vol.405 , pp. 837-846
- Pandey, A.¹ Mann, M.²

16
- 0001922784
- Basic principles of antisense technology
- Edited by Crooke ST. New York: Marcel Dekker, Inc.
- (2001) Antisense Drug Technology - Principles, Strategies and Applications , pp. 1-28
- Crooke, S.T.¹

17
- 0033555551
- Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression
- (1999) J Biol Chem , vol.274 , pp. 1715-1722
- McKay, R.A.¹ Miraglia, L.L.² Cummins, L.J.³ Owens, S.R.⁴ Sasmor, H.⁵ Dean, N.M.⁶

18
- 0002314695
- Pharmacology of 2′-O-(2-methoxy)etyl-modified antisense oligonucleotides
- Edited by Crooke ST. New York: Marcel Dekker, Inc.
- (2001) Antisense Drug Technology - Principles, Strategies and Applications , pp. 319-338
- Dean, N.M.¹ Butler, M.² Monia, B.P.³ Manoharan, M.⁴

19
- 0035799557
- Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
- (2001) Nature , vol.411 , pp. 102-107
- Bulavin, D.V.¹ Higashimoto, Y.² Popoff, I.J.³ Gaarde, W.A.⁴ Basrur, V.⁵ Potapova, O.⁶ Appella, E.⁷ Fornace Jr., A.J.⁸

20
- 0035920229
- Identification of an estrogen-inducible phosphatase PP5 that converts MCF-7 human breast carcinoma cells into an estrogen-independent phenotype when expressed constitutively
- (2001) J Biol Chem , vol.276 , pp. 27638-27646
- Urban, G.¹ Golden, T.² Aragon, I.V.³ Scammell, J.G.⁴ Dean, N.M.⁵ Honkanen, R.E.⁶

21
- 0035263289
- p27Kip1 is required for PTEN-induced G1 growth arrest
- (2001) Cancer Res , vol.61 , pp. 2105-2111
- Gottschalk, A.R.¹ Basila, D.² Wong, M.³ Dean, N.M.⁴ Brandts, C.H.⁵ Stokoe, D.⁶ Haas-Kogan, D.A.⁷

22
- 0035805493
- A constitutive cytoprotective pathway protects endothelial cells from lipopolysaccharide-induced apoptosis
- (2001) J Biol Chem , vol.276 , pp. 14924-14934
- Bannerman, D.D.¹ Tupper, J.C.² Ricketts, W.A.³ Bennett, C.F.⁴ Winn, R.K.⁵ Harlan, J.M.⁶

23
- 0033258543
- Pleiotropic cell-division defects and apoptosis induced by interference with survivin function
- (1999) Nat Cell Biol , vol.1 , pp. 461-466
- Li, F.¹ Ackermann, E.J.² Bennett, C.F.³ Rothermel, A.L.⁴ Plescia, J.⁵ Tognin, S.⁶ Villa, A.⁷ Marchisio, P.C.⁸ Altieri, D.C.⁹

24
- 0033526938
- L expression sensitizes normal human keratinocytes and epithelial cells to apoptotic stimuli
- (1999) Oncogene , vol.18 , pp. 4495-4504
- Taylor, J.K.¹ Zhang, Q.Q.² Monia, B.P.³ Marcusson, E.G.⁴ Dean, N.M.⁵

25
- 0035106880
- Piecing together the significance of splicing
- (2001) Nat Biotechnol , vol.19 , pp. 196
- Sorek, R.¹ Amitai, M.²

26
- 0003826861
- S through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides
- (1999) Nat Biotechnol , vol.17 , pp. 1097-1100
- Taylor, J.K.¹ Zhang, Q.Q.² Wyatt, J.R.³ Dean, N.M.⁴

27
- 0032892641
- Regulation of pre-mRNA splicing by antisense oligonucleotides
- (1999) Curr Opin Drug Discovery Dev , vol.2 , pp. 147-151
- Taylor, J.K.¹ Dean, N.M.²

28
- 0008344451
- Pre-mRNA splicing as a target for antisense oligonucleotides
- Edited by Crooke ST. New York: Marcel Dekker, Inc.
- (2001) Antisense Drug Technology - Principles, Strategies and Applications , pp. 517-540
- Kole, R.¹ Mercatante, D.²

29
- 0035869154
- Fully modified 2′MOE oligonucleotides redirect polyadenylation
- (2001) Nucleic Acid Res , vol.29 , pp. 1293-1299
- Vickers, T.A.¹ Wyatt, J.R.² Burckin, T.³ Bennett, C.F.⁴ Freier, S.M.⁵

30
- 0032064211
- Optimizing the impact of genomics on drug discovery and development
- (1998) Nat Biotechnol , vol.16 , Issue.SUPPL. , pp. 29-30
- Crooke, S.T.¹

31
- 0002250869
- Pharmacokinetic properties in animals
- Edited by Crooke ST. New York: Marcel Dekker, Inc.
- (2001) Antisense Drug Technology - Principles, Strategies and Applications , pp. 119-154
- Geary, R.¹ Yu, R.² Leeds, J.³ Templin, M.⁴ Watanabe, T.⁵ Henry, S.⁶ Levin, A.⁷

32
- 0033891369
- Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis
- (2000) Nat Biotechnol , vol.18 , pp. 862-867
- Zhang, H.¹ Cook, J.² Nickel, J.³ Yu, R.⁴ Stecker, K.⁵ Myers, K.⁶ Dean, N.M.⁷

33
- 0035142861
- Pharmacokinetics and pharmacodynamics of an antisense phosphorothioate oligonucleotide targeting Fas mRNA in mice
- (2001) J Pharmacol Exp Ther , vol.296 , pp. 388-395
- Yu, R.Z.¹ Zhang, H.² Geary, R.S.³ Graham, M.⁴ Masarjian, L.⁵ Lemonidis, K.⁶ Crooke, R.⁷ Dean, N.M.⁸ Levin, A.A.⁹

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.