Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras

Journal of Biological Chemistry

Volumn 271, Issue 24, 1996, Pages 14533-14540

  Monia, Brett P ^a   Johnston, Joseph F ^a   Sasmor, Henri ^a   Cummins, Lendell L ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; NUCLEASE; PHOSPHOROTHIOIC ACID; RNA;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NORTHERN BLOTTING; ONCOGENE RAS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CELL LINE; CHIMERA; DRUG DESIGN; ENDODEOXYRIBONUCLEASES; GENES, RAS; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHODIESTERASE I; PHOSPHORIC DIESTER HYDROLASES; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THIONUCLEOTIDES; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 15844400778     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.24.14533     Document Type: Article

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