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Volumn 39, Issue 37, 2000, Pages 11319-11329
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Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants
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Author keywords
[No Author keywords available]
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Indexed keywords
CYTOCHROME P450;
HYDROGEN PEROXIDE;
IRON COMPLEX;
MICROSOME ENZYME;
MUTANT PROTEIN;
OXYGEN;
PHENACETIN;
RECOMBINANT ENZYME;
REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;
ARTICLE;
CATALYSIS;
ELECTRON TRANSPORT;
ENZYME ACTIVITY;
ESCHERICHIA COLI;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
KINETICS;
MICROSOME;
MUTATION;
NONHUMAN;
OXIDATION;
PRIORITY JOURNAL;
SYNTHESIS;
ULTRAVIOLET SPECTROSCOPY;
XENOBIOTIC METABOLISM;
BINDING SITES;
CATALYSIS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CYTOCHROME P-450 CYP1A2;
DEUTERIUM;
ENZYME ACTIVATION;
FERRIC COMPOUNDS;
HUMANS;
HYDROGEN PEROXIDE;
KINETICS;
MUTAGENESIS, SITE-DIRECTED;
NADP;
OXIDATION-REDUCTION;
PHENACETIN;
RECOMBINANT PROTEINS;
TERT-BUTYLHYDROPEROXIDE;
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EID: 0034687092
PISSN: 00062960
EISSN: None
Source Type: Journal
DOI: 10.1021/bi000869u Document Type: Article |
Times cited : (135)
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References (76)
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