Identification of retained N-formylmethionine in bacterial recombinant mammalian cytochrome P450 proteins with the N-terminal sequence MALLLAVFL...: Roles of residues 3-5 in retention and membrane topology

Biochemistry

Volumn 35, Issue 31, 1996, Pages 10031-10040

  Dong, Mi Sook ^a   Chastine Bell, L ^a   Guo, Zuyu ^a,b   Phillips, Dennis R ^a,c   Blair, Ian A ^a   Peter Guengerich, F ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Rhone Poulenc Rorer ^*  (United States)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; FORMYLMETHIONINE;

AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL MEMBRANE; CYTOSOL; ESCHERICHIA COLI; HYDROLYSIS; HYDROPHOBICITY; MEMBRANE STRUCTURE; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SPHEROPLAST;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; ISOENZYMES; MAMMALS; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; N-FORMYLMETHIONINE; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPHEROPLASTS; SUBSTRATE SPECIFICITY; THROMBIN;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0029763107     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960873z     Document Type: Article

References (65)

1. Barnes, H. J., Arlotto, M. P., & Waterman, M. R. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 5597-5601.
2. Bernstein, H. D., Portiz, M. A., Strub, K., Hoben, P. J., Brenner, S., & Walter, P. (1989) Nature 340, 482-486.
3. Bork, R. W., Muto, T., Beaune, P. H., Srivastava, P. K., Lloyd, R. S., & Guengerich, F. P. (1989) J. Biol. Chem. 264, 910-919.
4. Briggs, M. S., & Gierasch, L. M. (1986) Adv. Protein Chem. 38, 109-180.
5. Brown, C. A., & Black, S. D. (1989) J. Biol. Chem. 264, 4442-4449.
6. Cummings, D. J., & Domenico, J. M. (1988) J. Mol. Biol. 204, 815-839.
7. Cummings, D. J., McNally, K. L., Domenico, J. M., & Matsuura, E. T. (1990) Curr. Genet. 17, 375-402.
8. De Lemos-Chiarandini, C., Frey, A. B., Sabatini, D. D., & Kreibich, G. (1987) J. Cell Biol. 104, 209-219.
9. Dong, M.-S., Yamazaki, H., Guo, Z., & Guengerich, F. P. (1996) Arch. Biochem. Biophys. 327, 11-19.
10. Eliasson, E., Mkrtchian, S., Halpert, J. R., & Ingelman-Sundberg, M. (1994) J. Biol. Chem. 269, 18378-18383.
11. Flinta, C., Persson, B., Jörnvall, H., & von Heijne, G. (1986) Eur. J. Biochem. 154, 193-196.
12. Gillam, E. M. J., Baba, T., Kim, B.-R., Ohmori, S., & Guengerich, F. P. (1993) Arch. Biochem. Biophys. 305, 123-131.
13. Gillam, E. M. J., Guo, Z., & Guengerich, F. P. (1994) Arch. Biochem. Biophys. 312, 59-66.
14. Gillam, E. M. J., Guo, Z., Martin, M. V., Jenkins, C. M., & Guengerich, F. P. (1995a) Arch. Biochem. Biophys. 319, 540-550.
15. Gillam, E. M. J., Guo, Z., Ueng, Y.-F., Yamazaki, H., Cock, I., Reilly, P. E. B., Hooper, W. D., & Guengerich, F. P. (1995b) Arch. Biochem. Biophys. 317, 374-384.
16. Gonzalez, F. J., Aoyama, T., & Gelboin, H. V. (1991) Methods Enzymol. 206, 85-92.
17. Guengerich, F. P. (1977) J. Biol. Chem. 252, 3970-3979.
18. Guengerich, F. P. (1991) J. Biol. Chem. 266, 10019-10022.
19. Guengerich, F. P. (1994) in Principles and Methods of Toxicology (Hayes, A. W., Ed.) pp 1259-1313, Raven Press, New York.
20. Guengerich, F. P., Gillam, E. M. J., & Shimada, T. (1996a) Crit. Rev. Toxicol. (in press).
21. Guengerich, F. P., Martin, M. V., Guo, Z., & Chun, Y.-J. (1996a) Methods Enzymol. (in press).
22. Guo, Z., Gillam, E. M. J, Ohmori, S., Tukey, R. H., & Guengerich, F. P. (1994) Arch. Biochem. Biophys. 312, 436-446.
23. Hall, L. A., & Kaesberg, P. (1973) J. Mol. Biol. 79, 531-537.
24. Hauschild-Rogat, P. (1968) Mol. Gen. Genet. 102, 95-101.
25. Housman, D., Gillespie, D., & Lodish, H. F. (1972) J. Mol. Biol. 65, 163-166.
26. Jaeger, J. A., Turner, D. H., & Zuker, M. (1989a) Proc. Natl. Acad. Sci. U.S.A. 86, 7706-7710.
27. Jaeger, J. A., Turner, D. H., & Zuker, M. (1989b) Methods Enzymol. 183, 281-306.
28. Jansson, I., Curti, M., Epstein, P. M., Peterson, J. A., & Schenkman, J. B. (1990) Arch. Biochem. Biophys. 283, 285-292.
29. Josephy, P. D., DeBruin, L. S., Lord, H. L., Oak, J., Evans, D. H., Guo, Z., Dong, M.-S., & Guengerich, F. P. (1995) Cancer Res. 55, 799-802.
30. Kaminsky, L. S., Fasco, M. J., & Guengerich, F. P. (1981) Methods Enzymol. 74, 262-272.
31. Kempf, A., Zanger, U. M., & Meyer, U. A. (1995) Arch. Biochem. Biophys. 321, 277-288.
32. Kyte, J., & Doolittle, R. F. (1982) J. Mol. Biol. 157, 105-132.
33. Laemmli, U. K. (1970) Nature 227, 680-685.
34. LeGendre, N., & Matsudaira, P. (1988) BioTechniques 6, 154-159.
35. LeGendre, N., Manfield, M., Weiss, A., & Matsudaira, P. (1993) in A Practical Guide to Protein and Peptide Purification for Microsequencing (Matsudaira, P., Ed.) pp 71-101, Academic Press, San Diego.
36. Lomri, N., Gu, Q., & Cashman, J. R. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 1685-1689.
37. MacFarlane, J., & Müller, M. (1995) Eur. J. Biochem. 233, 766-771.
38. Meinnel, T., Mechulam, Y., & Blanquet, S. (1993) Biochimie 75, 1061-1075.
39. Milligan, D. L., & Koshland, D. E., Jr. (1990) J. Biol. Chem. 265, 4455-4460.
40. Nicholas, R. A., Lamson, D. R., & Schultz, D. E. (1993) J. Biol. Chem. 268, 5632-5641.
41. Pernecky, S. J., Olken, N. M., Bestervelt, L. L., & Coon, M. J. (1995) Arch. Biochem. Biophys. 318, 446-456.
42. Poritz, M. A., Strub, K., & Walter, P. (1988) Cell 55, 4-6.
43. Porter, T. D., & Coon, M. J. (1991) J. Biol. Chem. 266, 13469-13472.
44. Römisch, K., Webb, J., Herz, J., Prehn, S., Frank, R.. Vingron, M., & Dobberstein, B. (1989) Nature 340, 478-482.
45. Sakaguchi, M., Mihara, K.. & Sato, R. (1987) EMBO J. 6, 2425-2431.
46. Sakaguchi, M., Tomiyoshi, R., Kuroiwa, T., Mihara, K., & Omura, T. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 16-19.
47. Sakaki, T., Oeda, K., Yabusaki, Y., & Ohkawa, H. (1986) J. Biochem. 99, 741-749.
48. Sambrook, J., Fritsch, E. F., & Maniatis, T. (1989) in Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
49. Sandhu, P., Baba, T., & Guengerich, F. P. (1993) Arch. Biochem. Biophys. 306, 443-450.
50. Sandhu, P., Guo, Z., Baba, T., Martin, M. V., Tukey, R. H., & Guengerich, F. P. (1994) Arch. Biochem. Biophys. 309, 168-177.
51. Sanger, F., Nicklen, S., & Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
52. Scheller, U., Kraft, R., Schröder, K.-L., & Schunck, W.-H. (1994) J. Biol. Chem. 269, 12779-12783.
53. Shimozawa, O., Sakaguchi, M., Ogawa, H., Harada, N., Mihara, K., & Omura, T. (1993) J. Biol. Chem. 268, 21399-21402.
54. Sueyoshi, T., Park, L. J., Moore, R., Juvonen, R. O., & Negishi, M. (1995) Arch. Biochem. Biophys. 322, 265-271.
55. Tarr, G. E., Black, S. D., Fujita, V. S., & Coon, M. J. (1983) Proc. Natl. Acad. Sci. U.S.A. 80, 6552-6556.
56. Tsunasawa, S., Yutani, K., Ogasahara, K., Taketani, M., Yasuoka, N., Kakudo, M., & Sugino, Y. (1983) Agric. Biol. Chem. 47, 1393-1395.
57. Vergeres, G., Winterhalter, K. H., & Richter, C. (1989) Biochemistry 28, 3650-3655.
58. Wada, A., Mathew, P. A., Barnes, H. J., Sanders, D., Estabrook, R. W., & Waterman, M. R. (1991) Arch. Biochem. Biophys. 290, 376-380.
59. Wickner, W., Driessen, A. J. M., & Haitl, F. U. (1991) Annu. Rev. Biochem. 60, 101-124.
60. Wray, W., Boulikas, T., Wray, V. P., & Hancock, R. (1981) Anal. Biochem. 118, 197-203.
61. Wu, H. C., & Tokunaga, M. (1986) Curr. Top. Microbiol. Immunol. 125, 127-157.
62. Yamazaki, S., Kato, S., Suhara, K., Sakaguchi, M., Mihara, K., & Omura, T. (1993) J. Biochem. (Tokyo) 114, 652-657.
63. Zuber, M. X., John, M. E., Okamura, T., Simpson, E. R., & Waterman, M. R. (1986a) J. Biol. Chem. 261, 2475-2482.
64. Zuber, M. X., Simpson, E. R., & Waterman, M. R. (1986b) Science 234, 1258-1261.
65. Zuker, M. (1989) Science 244, 48-52.