Structure of human microsomal cytochrome P450 2C8: Evidence for a peripheral fatty acid binding site

Journal of Biological Chemistry

Volumn 279, Issue 10, 2004, Pages 9497-9503

  Schoch, Guillaume A ^a   Yano, Jason K ^a   Wester, Michael R ^a   Griffin, Keith J ^a   Stout, C David ^a   Johnson, Eric F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; CRYSTALLIZATION; DRUG INTERACTIONS; DRUG THERAPY; FATTY ACIDS; HYDROPHOBICITY; MASS SPECTROMETRY; METABOLISM; MOLECULAR STRUCTURE; PURIFICATION; X RAY CRYSTALLOGRAPHY;

DRUG-METABOLIZING ENZYMES; THERAPEUTIC DRUGS;

CYTOLOGY;

ARACHIDONIC ACID; CYTOCHROME P450 2C8; DRUG METABOLIZING ENZYME; FATTY ACID BINDING PROTEIN; HISTIDINE; MEMBRANE PROTEIN; PALMITIC ACID;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING SITE; BIOAVAILABILITY; CRYSTALLIZATION; DRUG INTERACTION; HYDROPHOBICITY; MICROSOME MEMBRANE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; XENOBIOTIC METABOLISM;

ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; DIMERIZATION; FATTY ACIDS; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION;

MAMMALIA;

EID: 1542364450     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312516200     Document Type: Article

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