Elucidation of distinct ligand binding sites for cytochrome P450 3A4

Biochemistry

Volumn 39, Issue 20, 2000, Pages 5929-5939

  Hosea, Natilie A ^a,b   Miller, Grover P ^a   Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; AMINE; CYTOCHROME P450 3A4; INDINAVIR; MIDAZOLAM; MORPHICEPTIN; TESTOSTERONE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL BOND; ENZYME BINDING; ENZYME SPECIFICITY; LIGAND BINDING; OXIDATION; PRIORITY JOURNAL;

BINDING SITES; BINDING, COMPETITIVE; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; HIV PROTEASE INHIBITORS; HUMANS; INDINAVIR; LIGANDS; MIXED FUNCTION OXYGENASES; MODELS, CHEMICAL; OLIGOPEPTIDES; OXIDATION-REDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0034705191     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992765t     Document Type: Article

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