HIV-1 reverse transcriptase: A therapeutical target in the spotlight

Current Medicinal Chemistry

Volumn 13, Issue 3, 2006, Pages 313-324

  Castro, H C ^a   Loureiro, N I V ^a,b   Pujol Luz, M ^a,b   Souza, A M T ^a,b   Albuquerque, M G ^b   Santos, D O ^a   Cabral, L M ^b   Frugulhetti, I C ^a   Rodrigues, C R ^b  

^a FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

AIDS; Antiretroviral; DNA; Non nucleoside; Nucleoside; Nucleotide; Reverse transcriptase; RNA

Indexed keywords

1 [(2 HYDROXYETHOXY)METHYL] 6 (PHENYLTHIO)THYMINE; 1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); ABACAVIR; ADEFOVIR; CAPRAVIRINE; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; COMPLEMENTARY DNA; DELAVIRDINE; DIDANOSINE; DOUBLE STRANDED DNA; EFAVIRENZ; EMTRICITABINE; LAMIVUDINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; METALLOPORPHYRIN; N [4 [[[6,7 DIHYDRO 2 (4 METHYLPHENYL) 5H BENZOCYCLOHEPTEN 8 YL]CARBONYL]AMINO]BENZYL] N,N DIMETHYL 2H TETRAHYDROPYRAN 4 AMINIUM CHLORIDE; NEVIRAPINE; RANTES; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; TALVIRALINE; TENOFOVIR; UNINDEXED DRUG; VIRUS RNA; ZALCITABINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIBIOTIC RESISTANCE; CATALYSIS; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVITY; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; PROTEIN STRUCTURE; REVERSE TRANSCRIPTION; REVIEW; STRUCTURE ANALYSIS; VIRUS STRAIN; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PHYSIOLOGY; PROTEIN CONFORMATION; VIRUS REPLICATION;

DRUG RESISTANCE, VIRAL; HIV INFECTIONS; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; REVERSE TRANSCRIPTASE INHIBITORS; VIRUS REPLICATION;

EID: 33645891478     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986706775476089     Document Type: Review

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