Characterization of the p68/p58 heterodimer of human immunodeficiency virus type 2 reverse transcriptase

Biochemistry

Volumn 35, Issue 6, 1996, Pages 1911-1917

  Fan, Naisheng ^a   Rank, Kenneth B ^a   Poppe, Susan M ^a   Tarpley, W Gary ^a   Sharma, Satish K ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM ION; MANGANESE; POLYADENYLIC ACID; POLYTHYMIDYLIC ACID; PROTEINASE; RECOMBINANT PROTEIN; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE; THYMIDINE TRIPHOSPHATE;

ARTICLE; COMPETITIVE INHIBITION; DNA RNA HYBRIDIZATION; ENZYME DEGRADATION; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; HUMAN IMMUNODEFICIENCY VIRUS 2; HYDROLYSIS; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL;

ASPARTIC ENDOPEPTIDASES; BASE SEQUENCE; CATIONS, DIVALENT; DNA PRIMERS; DNA, VIRAL; GENES, GAG; HIV-2; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; POLY A; POLY T; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE INHIBITORS; RIBONUCLEASE H, CALF THYMUS; RNA-DIRECTED DNA POLYMERASE; SUBSTRATE SPECIFICITY; THYMINE NUCLEOTIDES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 0030032149     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9516440     Document Type: Article

References (33)

1. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
2. Chandra, P., Vogel, A., & Gerber, T. (1985) Cancer Res. 45, 4677-4684.
3. Chattophadhyay, D., Evans, D. B., Deibel, M. R.; Vosters, A. F., Eckenrode, F. M., Einsphar, H. M., Hui, J. O., Tomasselli, A. G., Zurcher-Neely, H. A., Heinrikson, R. L., & Sharma, S. K. (1992) J. Biol. Chem. 267, 14227-14232.
4. Clavel, F., Guetard, D., Brun-Vezinet, F.; Chamaret, S., Rey, M. A., Santos-Ferreira, M. O., Laurent, A. G., Dauguet, C., Katlama, C., Rouzioux, C., Klatzmann, D., Champalimaud, J. L., & Montagnier, L. (1986a) Science 233, 343-346.
5. Clavel, F., Guyder, M., Guetard, D., Salle, M., Montagnier, L., & Alizon, M. (1986b) Nature 324, 691-695.
6. De Clercq, E. (1994) Biochem. Pharmacol. 47, 155-169.
7. DeVico, A. L., Copeland, T. D., Veronese, F. D. M., Oroszlan, S., Gallo, R. C., & Sarngadharan, G. (1989) AIDS Res. Hum. Retroviruses 5, 51-60.
8. Evans, D. B., Fan, N., Swaney, S. M., Tarpley, W. G., & Sharma, S. K. (1994) J. Biol. Chem. 269, 21741-21747.
9. Fan, N., Rank, K. B., Leone, J. W., Heinrikson, R. L., Bannow, C. A., Smith, C. W., Evans, D. B., Poppe, S. M., Tarpley, W. G., Rothrock, D. J., Tomasselli, A. G., & Sharma, S. K. (1995a) J. Biol. Chem. 270, 13573-13579.
10. Fan, N., Evans, D. B., Rank, K. B., Thomas, R. C., Tarpley, W. G., & Sharma, S. K. (1995b) FEBS Lett. 359, 33-38.
11. Goff, S. P. (1990) J. Acquired Immune Defic. Syndr. 3, 817-831.
12. Guyader, M., Emerman, M., Sonigo, P., Clavel, F., Montagnier, L., & Alizon, M. (1987) Nature 326, 662-669.
13. Hizi, A., Tal, R., & Hughes, S. H. (1991a) Virology 180, 339-346.
14. Hizi, A., Tal, R., Shaharabany, M., & Loya, S. (1991b) J. Biol. Chem. 266, 6230-6239
15. Laemmli, U. K. (1970) Nature 227, 680-685.
16. LeGrice, S. F. J., & Gruninger-Leitch, F. (1990) Eur. J. Biochem. 168, 30-36.
17. LeGrice, S. F. J., Zehnle, R., & Mous, J. A. (1988) J. Virol. 62, 2525-2529.
18. Lowe, D. M., Aitken, A., Bradley, C., Darby, G. K., Larder, B. A., Poweli, K. L., Purifoy, D. J. M , Tisdale, M., & Stammers, D. K. (1988) Biochemistry 27, 8884-8888.
19. Lowe, D. M., Palmer, V., Kemp, S. D., & Larder, B. A. (1991) FEBS Lett. 282, 231-234.
20. Mitsuya, H., Yarchoan, R., & Border, S. (1990) Science 249, 1533-1544.
21. Muller, B., Restle, T., Kuhnel, H., & Goody, R. S. (1991) J. Biol. Chem. 266, 14709-14713.
22. Peach, M., Rubinek, T., & Hizi, A. (1995) J. Virol. 69, 509-512.
23. Prasad, V., & Goff, S. P. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 3104-3108.
24. Ratner, L., Haseltine, W., Patarca, R., Livak, K. J., Starcich, B., Joseph, S., Doran, E. R., Rafalski, J. A., Whitehorn, E. A., Baumeister, K., Ivanoff, L., Petteway, S. R., Pearson, M. L., Leutenberger, J. A., Papas, T. S., Ghrayeb, J., Chang, N. T., Gallo, R. C., & Wong-Staal, F. (1985) Nature 313, 277-284.
25. Romero, D. L., Busso, M., Tan, C.-K., Reusser, F., Palmer, J. R., Poppe, S. M., Aristoff, P. A., Downey, K. M., So, A. G., Resnick, L., & Tarpley, W. G. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 8806-8810.
26. Shaharabany, M., & Hizi, A. (1992) J. Biol. Chem. 25, 3674-3678.
27. Sharma, S. K., Evans, D. B., Vosters, A. F., McQuade, T. J., & Tarpley, W. G. (1991) Biotechnol. Appl. Biochem. 14, 69-81.
28. Sharma, S. K., Evans, D. B., Vosters, A. F., Chattopadhyay, D., Hoogerheide, J. G., & Campbell, C. M. (1992) Methods: A Companion to Methods in Enzymology, Vol. 4, pp 57-67, Academic, San Diego, CA.
29. Tong, L., Cardozo, M., Jones, P.-J., & Adams, J. (1993) Bioorg. Med. Chem. Lett. 3, 721-726.
30. Volkmann, S., Wohr, B. G., Tisdale, M., & Moelling, K. (1993) J. Biol. Chem. 268, 2674-2683.
31. Warren, T. C., Miglietta, J. J., Shrutkowski, A., Rose, J. M., Rogers, S. L., Lubbe, K., Shih, C. K., Caviness, G. O., Ingraham, R., Palladino, D. E. H., David, E., Chow, G. C., Kopp, E. B., Cohen, K. A., Glinski, J. A., Farina, P. R., & Grob, P. M. (1992) Protein Expression Purif. 3, 479-487.
32. Zagury, J. F., Franchini, G., Reitz, M., Collalti, E., Starcich, B., Hali, L., Fargoli, K., Jagodzinski, L., Guo, H.-G., Laure, F., Arya, S. K., Josephs, S., Zagury, D., Wong-Staal, F., & Gallo, R. C. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 5941-5945.
33. Zhan, X., Tan, C.-K., Scott, W. A., Mian, A. M., Downey, K. M., & So, A. (1994) Biochemistry 33, 1366-1372.