The HIV-1 reverse transcription (RT) process as target for RT inhibitors

Medicinal Research Reviews

Volumn 20, Issue 2, 2000, Pages 129-154

  Jonckheere, Heidi ^a   Anné, Jozef ^a   De Clercq, Erik ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

DNA polymerization; Drug resistance; Human Immunodeficiency virus (HIV); Reverse transcriptase (RT); Reverse transcription

Indexed keywords

2 ETHYL 7 FLUORO 1,2,3,4 TETRAHYDRO 3 OXO 1 QUINOXALINECARBOXYLIC ACID ISOPROPYL ESTER; ABACAVIR; ADEFOVIR; CAPRAVIRINE; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EMIVIRINE; LAMIVUDINE; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; TIVIRAPINE; UNCLASSIFIED DRUG; ZALCITABINE; ZIDOVUDINE;

ARTICLE; CLINICAL TRIAL; DNA SYNTHESIS; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITOR INTERACTION; ENZYME MECHANISM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; REVERSE TRANSCRIPTION; TRANSCRIPTION REGULATION; VIRUS MUTATION; VIRUS TRANSCRIPTION;

ANTI-HIV AGENTS; DRUG RESISTANCE, MICROBIAL; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; PROTEIN CONFORMATION; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC;

EID: 0034059835     PISSN: 01986325     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1128(200003)20:2<129::AID-MED2>3.0.CO;2-A     Document Type: Article

References (159)