Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment)

Journal of Biological Chemistry

Volumn 274, Issue 5, 1999, Pages 3067-3075

  Minnick, Dana T ^a,c   Bebenek, Katarzyna ^a   Osheroff, Wendy P ^a   Turner Jr , Robert M ^b   Astatke, Mekbib ^b,d   Liu, Lixing ^b   Kunkel, Thomas A ^a   Joyce, Catherine M ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b YALE UNIVERSITY   (United States)

^c Clinical Data Inc   (United States)

^d Life Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA;

AMINO ACID COMPOSITION; AMINO ACID SUBSTITUTION; ARTICLE; BASE PAIRING; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ESCHERICHIA COLI; FRAMESHIFT MUTATION; GENE INSERTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; SEQUENCE ANALYSIS;

AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; DNA POLYMERASE I; ESCHERICHIA COLI; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI;

EID: 0033613841     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.5.3067     Document Type: Article

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