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Volumn 36, Issue 9, 2004, Pages 1752-1766

'Binding, bending and bonding': Polypurine tract-primed initiation of plus-strand DNA synthesis in human immunodeficiency virus

Author keywords

2,4 difluoro 5 methylbenzene; 2 fluoro 4 methylbenzene; central polypurine tract; cPPT; D; F; HIV; human immunodeficiency virus; Mo MLV; Moloney murine leukemia virus; polypurine tract; PPT; Retrovirus; reverse transcriptase; ribonuclease H; RNase H; RT

Indexed keywords

PRIMER RNA; PURINE; RIBONUCLEASE H; RNA; RNA DIRECTED DNA POLYMERASE; VIRUS DNA;

EID: 2942525660     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2004.02.016     Document Type: Review
Times cited : (91)

References (73)
  • 1
    • 0034003832 scopus 로고    scopus 로고
    • Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5′ plus-strand DNA ends in vivo
    • Bacharach E., Gonsky J., Lim D., Goff S.P. Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5′ plus-strand DNA ends in vivo. Journal of Virology. 74:2000;4755-4764
    • (2000) Journal of Virology , vol.74 , pp. 4755-4764
    • Bacharach, E.1    Gonsky, J.2    Lim, D.3    Goff, S.P.4
  • 2
    • 0029893953 scopus 로고    scopus 로고
    • Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis
    • Beard W.A., Minnick D.T., Wade C.L., Prasad R., Won R.L., Kumar A., et al. Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis. Journal of Biological Chemistry. 271:1996;12213-12220
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 12213-12220
    • Beard, W.A.1    Minnick, D.T.2    Wade, C.L.3    Prasad, R.4    Won, R.L.5    Kumar, A.6
  • 3
    • 0019351623 scopus 로고
    • Viral DNA synthesized in vitro by avian retrovirus particles permeabilized with melittin. I. Kinetics of synthesis and size of minus- and plus-strand transcripts
    • Boone L.R., Skalka A.M. Viral DNA synthesized in vitro by avian retrovirus particles permeabilized with melittin. I. Kinetics of synthesis and size of minus- and plus-strand transcripts. Journal of Virology. 37:1981;109-116
    • (1981) Journal of Virology , vol.37 , pp. 109-116
    • Boone, L.R.1    Skalka, A.M.2
  • 4
    • 0025915560 scopus 로고
    • A single-stranded gap in human immunodeficiency virus unintegrated linear DNA defined by a central copy of the polypurine tract
    • Charneau P., Clavel F. A single-stranded gap in human immunodeficiency virus unintegrated linear DNA defined by a central copy of the polypurine tract. Journal of Virology. 65:1991;2415-2421
    • (1991) Journal of Virology , vol.65 , pp. 2415-2421
    • Charneau, P.1    Clavel, F.2
  • 5
    • 0026506252 scopus 로고
    • A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication
    • Charneau P., Alizon M., Clavel F. A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication. Journal of Virology. 66:1992;2814-2820
    • (1992) Journal of Virology , vol.66 , pp. 2814-2820
    • Charneau, P.1    Alizon, M.2    Clavel, F.3
  • 7
    • 0036252492 scopus 로고    scopus 로고
    • High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter
    • Demaison C., Parsley K., Brouns G., Scherr M., Battmer K., Kinnon C., et al. High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter. Human Gene Therapy. 13:2002;803-813
    • (2002) Human Gene Therapy , vol.13 , pp. 803-813
    • Demaison, C.1    Parsley, K.2    Brouns, G.3    Scherr, M.4    Battmer, K.5    Kinnon, C.6
  • 8
    • 0025912708 scopus 로고
    • Polymerization and RNase H activities of the reverse transcriptases from avian myeloblastosis, human immunodeficiency, and Moloney murine leukemia viruses are functionally uncoupled
    • DeStefano J.J., Buiser R.G., Mallaber L.M., Myers T.W., Bambara R.A., Fay P.J. Polymerization and RNase H activities of the reverse transcriptases from avian myeloblastosis, human immunodeficiency, and Moloney murine leukemia viruses are functionally uncoupled. Journal of Biological Chemistry. 266:1991;7423-7431
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 7423-7431
    • Destefano, J.J.1    Buiser, R.G.2    Mallaber, L.M.3    Myers, T.W.4    Bambara, R.A.5    Fay, P.J.6
  • 9
    • 0027328663 scopus 로고
    • Parameters that influence the binding of human immunodeficiency virus reverse transcriptase to nucleic acid structures
    • DeStefano J.J., Bambara R.A., Fay P.J. Parameters that influence the binding of human immunodeficiency virus reverse transcriptase to nucleic acid structures. Biochemistry. 32:1993;6908-6915
    • (1993) Biochemistry , vol.32 , pp. 6908-6915
    • Destefano, J.J.1    Bambara, R.A.2    Fay, P.J.3
  • 10
    • 0028024176 scopus 로고
    • Quantitative analysis of RNA cleavage during RNA-directed DNA synthesis by human immunodeficiency and avian myeloblastosis virus reverse transcriptases
    • DeStefano J.J., Mallaber L.M., Fay P.J., Bambara R.A. Quantitative analysis of RNA cleavage during RNA-directed DNA synthesis by human immunodeficiency and avian myeloblastosis virus reverse transcriptases. Nucleic Acids Research. 22:1994;3793-3800
    • (1994) Nucleic Acids Research , vol.22 , pp. 3793-3800
    • Destefano, J.J.1    Mallaber, L.M.2    Fay, P.J.3    Bambara, R.A.4
  • 11
    • 0018877119 scopus 로고
    • Structure of murine sarcoma virus DNA replicative intermediates synthesized in vitro
    • Dina D., Benz E.W. Jr. Structure of murine sarcoma virus DNA replicative intermediates synthesized in vitro. Journal of Virology. 33:1980;377-389
    • (1980) Journal of Virology , vol.33 , pp. 377-389
    • Dina, D.1    Benz Jr., E.W.2
  • 12
    • 0026342152 scopus 로고
    • Analysis of the RNA- and DNA-dependent DNA polymerase activities of point mutants of HIV-1 reverse transcriptase lacking ribonuclease H activity
    • Dudding L.R., Nkabinde N.C., Mizrahi V. Analysis of the RNA- and DNA-dependent DNA polymerase activities of point mutants of HIV-1 reverse transcriptase lacking ribonuclease H activity. Biochemistry. 30:1991;10498-10506
    • (1991) Biochemistry , vol.30 , pp. 10498-10506
    • Dudding, L.R.1    Nkabinde, N.C.2    Mizrahi, V.3
  • 13
    • 0036889124 scopus 로고    scopus 로고
    • Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import
    • Dvorin J.D., Bell P., Maul G.G., Yamashita M., Emerman M., Malim M.H. Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import. Journal of Virology. 76:2002;12087-12096
    • (2002) Journal of Virology , vol.76 , pp. 12087-12096
    • Dvorin, J.D.1    Bell, P.2    Maul, G.G.3    Yamashita, M.4    Emerman, M.5    Malim, M.H.6
  • 14
    • 0031556022 scopus 로고    scopus 로고
    • Solution structure of r(gaggacug):d(CAGTCCTC) hybrid: Implications for the initiation of HIV-1 (+)-strand synthesis
    • Fedoroff O.Y., Ge Y., Reid B.R. Solution structure of r(gaggacug):d(CAGTCCTC) hybrid: Implications for the initiation of HIV-1 (+)-strand synthesis. Journal of Molecular Biology. 269:1997;225-239
    • (1997) Journal of Molecular Biology , vol.269 , pp. 225-239
    • Fedoroff, O.Y.1    Ge, Y.2    Reid, B.R.3
  • 15
    • 0021244732 scopus 로고
    • RNA-primed initiation of Moloney murine leukemia virus plus strands by reverse transcriptase in vitro
    • Finston W.I., Champoux J.J. RNA-primed initiation of Moloney murine leukemia virus plus strands by reverse transcriptase in vitro. Journal of Virology. 51:1984;26-33
    • (1984) Journal of Virology , vol.51 , pp. 26-33
    • Finston, W.I.1    Champoux, J.J.2
  • 16
    • 2142812180 scopus 로고    scopus 로고
    • Role of RNA primers in initiation of minus-strand and plus-strand DNA synthesis of the yeast retrotransposon Ty1
    • Friant S., Heyman T., Wilhelm F.X., Wilhelm M. Role of RNA primers in initiation of minus-strand and plus-strand DNA synthesis of the yeast retrotransposon Ty1. Biochimie. 78:1996;674-680
    • (1996) Biochimie , vol.78 , pp. 674-680
    • Friant, S.1    Heyman, T.2    Wilhelm, F.X.3    Wilhelm, M.4
  • 17
    • 0030924328 scopus 로고    scopus 로고
    • Mutating a conserved motif of the HIV-1 reverse transcriptase palm subdomain alters primer utilization
    • Ghosh M., Williams J., Powell M.D., Levin J.G., Le Grice S.F. Mutating a conserved motif of the HIV-1 reverse transcriptase palm subdomain alters primer utilization. Biochemistry. 36:1997;5758-5768
    • (1997) Biochemistry , vol.36 , pp. 5758-5768
    • Ghosh, M.1    Williams, J.2    Powell, M.D.3    Levin, J.G.4    Le Grice, S.F.5
  • 20
    • 0025314263 scopus 로고
    • Processing of the primer for plus strand DNA synthesis by human immunodeficiency virus 1 reverse transcriptase
    • Huber H.E., Richardson C.C. Processing of the primer for plus strand DNA synthesis by human immunodeficiency virus 1 reverse transcriptase. Journal of Biological Chemistry. 265:1990;10565-10573
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 10565-10573
    • Huber, H.E.1    Richardson, C.C.2
  • 21
    • 0025973399 scopus 로고
    • The plus strand is discontinuous in a subpopulation of unintegrated HIV-1 DNA
    • Hungnes O., Tjotta E., Grinde B. The plus strand is discontinuous in a subpopulation of unintegrated HIV-1 DNA. Archives of Virology. 116:1991;133-141
    • (1991) Archives of Virology , vol.116 , pp. 133-141
    • Hungnes, O.1    Tjotta, E.2    Grinde, B.3
  • 22
    • 0026806438 scopus 로고
    • Mutations in the central polypurine tract of HIV-1 result in delayed replication
    • Hungnes O., Tjotta E., Grinde B. Mutations in the central polypurine tract of HIV-1 result in delayed replication. Virology. 190:1992;440-442
    • (1992) Virology , vol.190 , pp. 440-442
    • Hungnes, O.1    Tjotta, E.2    Grinde, B.3
  • 23
    • 0032125698 scopus 로고    scopus 로고
    • Identification of a sequence element immediately upstream of the polypurine tract that is essential for replication of simian immunodeficiency virus
    • Ilyinskii P.O., Desrosiers R.C. Identification of a sequence element immediately upstream of the polypurine tract that is essential for replication of simian immunodeficiency virus. EMBO Journal. 17:1998;3766-3774
    • (1998) EMBO Journal , vol.17 , pp. 3766-3774
    • Ilyinskii, P.O.1    Desrosiers, R.C.2
  • 25
    • 0032540293 scopus 로고    scopus 로고
    • Characterization of RNA strand displacement synthesis by Moloney murine leukemia virus reverse transcriptase
    • Kelleher C.D., Champoux J.J. Characterization of RNA strand displacement synthesis by Moloney murine leukemia virus reverse transcriptase. Journal of Biological Chemistry. 273:1998;9976-9986
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 9976-9986
    • Kelleher, C.D.1    Champoux, J.J.2
  • 26
    • 0034724855 scopus 로고    scopus 로고
    • RNA degradation and primer selection by Moloney murine leukemia virus reverse transcriptase contribute to the accuracy of plus strand initiation
    • Kelleher C.D., Champoux J.J. RNA degradation and primer selection by Moloney murine leukemia virus reverse transcriptase contribute to the accuracy of plus strand initiation. Journal of Biological Chemistry. 275:2000;13061-13070
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 13061-13070
    • Kelleher, C.D.1    Champoux, J.J.2
  • 27
    • 0027238697 scopus 로고
    • Template-directed pausing of DNA synthesis by HIV-1 reverse transcriptase during polymerization of HIV-1 sequences in vitro
    • Klarmann G.J., Schauber C.A., Preston B.D. Template-directed pausing of DNA synthesis by HIV-1 reverse transcriptase during polymerization of HIV-1 sequences in vitro. Journal of Biological Chemistry. 268:1993;9793-9802
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 9793-9802
    • Klarmann, G.J.1    Schauber, C.A.2    Preston, B.D.3
  • 28
    • 0030729201 scopus 로고    scopus 로고
    • Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free system
    • Klarmann G.J., Yu H., Chen X., Dougherty J.P., Preston B.D. Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free system. Journal of Virology. 71:1997;9259-9269
    • (1997) Journal of Virology , vol.71 , pp. 9259-9269
    • Klarmann, G.J.1    Yu, H.2    Chen, X.3    Dougherty, J.P.4    Preston, B.D.5
  • 29
    • 0019381329 scopus 로고
    • Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus
    • Kung H.J., Fung Y.K., Majors J.E., Bishop J.M., Varmus H.E. Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus. Journal of Virology. 37:1981;127-138
    • (1981) Journal of Virology , vol.37 , pp. 127-138
    • Kung, H.J.1    Fung, Y.K.2    Majors, J.E.3    Bishop, J.M.4    Varmus, H.E.5
  • 30
    • 0037053370 scopus 로고    scopus 로고
    • Pre-existing distortions in nucleic acid structure aid polypurine tract selection by HIV-1 reverse transcriptase
    • Kvaratskhelia M., Budihas S.R., Le Grice S.F. Pre-existing distortions in nucleic acid structure aid polypurine tract selection by HIV-1 reverse transcriptase. Journal of Biological Chemistry. 277:2002;16689-16696
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 16689-16696
    • Kvaratskhelia, M.1    Budihas, S.R.2    Le Grice, S.F.3
  • 31
    • 0030776187 scopus 로고    scopus 로고
    • Plus-strand strong-stop DNA transfer in yeast Ty retrotransposons
    • Lauermann V., Boeke J.D. Plus-strand strong-stop DNA transfer in yeast Ty retrotransposons. EMBO Journal. 16:1997;6603-6612
    • (1997) EMBO Journal , vol.16 , pp. 6603-6612
    • Lauermann, V.1    Boeke, J.D.2
  • 32
    • 0037135570 scopus 로고    scopus 로고
    • Mutating conserved residues in the ribonuclease H domain of Ty3 reverse transcriptase affects specialized cleavage events
    • Lener D., Budihas S.R., Le Grice S.F. Mutating conserved residues in the ribonuclease H domain of Ty3 reverse transcriptase affects specialized cleavage events. Journal of Biological Chemistry. 277:2002;26486-26495
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 26486-26495
    • Lener, D.1    Budihas, S.R.2    Le Grice, S.F.3
  • 33
    • 0037698250 scopus 로고    scopus 로고
    • Nonpolar thymine isosteres in the ty3 polypurine tract DNA template modulate processing and provide a model for its recognition by ty3 reverse transcriptase
    • Lener D., Kvaratskhelia M., Le Grice S.F. Nonpolar thymine isosteres in the ty3 polypurine tract DNA template modulate processing and provide a model for its recognition by ty3 reverse transcriptase. Journal of Biological Chemistry. 278:2003;26526-26532
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 26526-26532
    • Lener, D.1    Kvaratskhelia, M.2    Le Grice, S.F.3
  • 34
    • 0025112945 scopus 로고
    • Template switching by reverse transcriptase during DNA synthesis
    • Luo G.X., Taylor J. Template switching by reverse transcriptase during DNA synthesis. Journal of Virology. 64:1990;4321-4328
    • (1990) Journal of Virology , vol.64 , pp. 4321-4328
    • Luo, G.X.1    Taylor, J.2
  • 35
    • 0141453593 scopus 로고    scopus 로고
    • Mutations in the 5′ end of the HIV-1 polypurine tract affect Rnase H cleavage specificity and virus titer
    • McWilliams M.J., Julias J.G., Sarafianos S.G., Alvord W.G., Arnold E., Hughes S.E. Mutations in the 5′ end of the HIV-1 polypurine tract affect Rnase H cleavage specificity and virus titer. Journal of Virology. 77:2003;11150-11157
    • (2003) Journal of Virology , vol.77 , pp. 11150-11157
    • McWilliams, M.J.1    Julias, J.G.2    Sarafianos, S.G.3    Alvord, W.G.4    Arnold, E.5    Hughes, S.E.6
  • 37
    • 0024453615 scopus 로고
    • Analysis of the ribonuclease H activity of HIV-1 reverse transcriptase using RNA.DNA hybrid substrates derived from the gag region of HIV-1
    • Mizrahi V. Analysis of the ribonuclease H activity of HIV-1 reverse transcriptase using RNA.DNA hybrid substrates derived from the gag region of HIV-1. Biochemistry. 28:1989;9088-9094
    • (1989) Biochemistry , vol.28 , pp. 9088-9094
    • Mizrahi, V.1
  • 38
    • 0015236835 scopus 로고
    • Association of viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids
    • Molling K., Bolognesi D.P., Bauer H., Busen W., Plassmann H.W., Hausen P. Association of viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids. Nature of New Biology. 234:1971;240-243
    • (1971) Nature of New Biology , vol.234 , pp. 240-243
    • Molling, K.1    Bolognesi, D.P.2    Bauer, H.3    Busen, W.4    Plassmann, H.W.5    Hausen, P.6
  • 40
    • 0019336915 scopus 로고
    • Avian retrovirus RNA-directed DNA synthesis by purified reverse transcriptase. Covalent linkage of RNA to plus strand DNA
    • Olsen J.C., Watson K.F. Avian retrovirus RNA-directed DNA synthesis by purified reverse transcriptase. Covalent linkage of RNA to plus strand DNA. Biochemical and Biophysical Research Communication. 97:1980;1376-1383
    • (1980) Biochemical and Biophysical Research Communication , vol.97 , pp. 1376-1383
    • Olsen, J.C.1    Watson, K.F.2
  • 41
    • 0021260272 scopus 로고
    • Evidence for involvement of an RNA primer in initiation of strong-stop plus DNA synthesis during reverse transcription in vitro
    • Omer C.A., Resnick R., Faras A.J. Evidence for involvement of an RNA primer in initiation of strong-stop plus DNA synthesis during reverse transcription in vitro. Journal of Virology. 50:1984;465-470
    • (1984) Journal of Virology , vol.50 , pp. 465-470
    • Omer, C.A.1    Resnick, R.2    Faras, A.J.3
  • 44
    • 0029955712 scopus 로고    scopus 로고
    • Sequence and structural determinants required for priming of plus-strand DNA synthesis by the human immunodeficiency virus type 1 polypurine tract
    • Powell M.D., Levin J.G. Sequence and structural determinants required for priming of plus-strand DNA synthesis by the human immunodeficiency virus type 1 polypurine tract. Journal of Virology. 70:1996;5288-5296
    • (1996) Journal of Virology , vol.70 , pp. 5288-5296
    • Powell, M.D.1    Levin, J.G.2
  • 45
    • 0030977397 scopus 로고    scopus 로고
    • Alanine-scanning mutations in the "primer grip" of p66 HIV-1 reverse transcriptase result in selective loss of RNA priming activity
    • Powell M.D., Ghosh M., Jacques P.S., Howard K.J., Le Grice S.F., Levin J.G. Alanine-scanning mutations in the "primer grip" of p66 HIV-1 reverse transcriptase result in selective loss of RNA priming activity. Journal of Biological Chemistry. 272:1997;13262-13269
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 13262-13269
    • Powell, M.D.1    Ghosh, M.2    Jacques, P.S.3    Howard, K.J.4    Le Grice, S.F.5    Levin, J.G.6
  • 46
    • 0033538339 scopus 로고    scopus 로고
    • Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer
    • Powell M.D., Beard W.A., Bebenek K., Howard K.J., Le Grice S.F., Darden T.A., et al. Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer. Journal of Biological Chemistry. 274:1999;19885-19893
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 19885-19893
    • Powell, M.D.1    Beard, W.A.2    Bebenek, K.3    Howard, K.J.4    Le Grice, S.F.5    Darden, T.A.6
  • 47
    • 0027414932 scopus 로고
    • The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase
    • Pullen K.A., Rattray A.J., Champoux J.J. The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase. Journal of Biological Chemistry. 268:1993;6221-6227
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 6221-6227
    • Pullen, K.A.1    Rattray, A.J.2    Champoux, J.J.3
  • 48
    • 0027965008 scopus 로고
    • The use of DNA and RNA oligonucleotides in hybrid structures with longer polynucleotide chains to probe the structural requirements for Moloney murine leukemia virus plus strand priming
    • Randolph C.A., Champoux J.J. The use of DNA and RNA oligonucleotides in hybrid structures with longer polynucleotide chains to probe the structural requirements for Moloney murine leukemia virus plus strand priming. Journal of Biological Chemistry. 269:1994;19207-19215
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 19207-19215
    • Randolph, C.A.1    Champoux, J.J.2
  • 49
    • 0024417604 scopus 로고
    • Plus-strand priming by Moloney murine leukemia virus. The sequence features important for cleavage by Rnase H
    • Rattray A.J., Champoux J.J. Plus-strand priming by Moloney murine leukemia virus. The sequence features important for cleavage by Rnase H. Journal of Molecular Biology. 208:1989;445-456
    • (1989) Journal of Molecular Biology , vol.208 , pp. 445-456
    • Rattray, A.J.1    Champoux, J.J.2
  • 50
    • 0030964781 scopus 로고    scopus 로고
    • Substituting a conserved residue of the ribonuclease H domain alters substrate hydrolysis by retroviral reverse transcriptase
    • Rausch J.W., Le Grice S.F. Substituting a conserved residue of the ribonuclease H domain alters substrate hydrolysis by retroviral reverse transcriptase. Journal of Biological Chemistry. 272:1997;8602-8610
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 8602-8610
    • Rausch, J.W.1    Le Grice, S.F.2
  • 51
    • 0037117744 scopus 로고    scopus 로고
    • Altering the RNase H primer grip of human immunodeficiency virus reverse transcriptase modifies cleavage specificity
    • Rausch J.W., Lener D., Miller J.T., Julias J.G., Hughes S.H., Le Grice S.F. Altering the RNase H primer grip of human immunodeficiency virus reverse transcriptase modifies cleavage specificity. Biochemistry. 41:2002;4856-4865
    • (2002) Biochemistry , vol.41 , pp. 4856-4865
    • Rausch, J.W.1    Lener, D.2    Miller, J.T.3    Julias, J.G.4    Hughes, S.H.5    Le Grice, S.F.6
  • 53
    • 0032902552 scopus 로고    scopus 로고
    • Effects of 3′ untranslated region mutations on plus-strand priming during Moloney murine leukemia virus replication
    • Robson N.D., Telesnitsky A. Effects of 3′ untranslated region mutations on plus-strand priming during Moloney murine leukemia virus replication. Journal of Virology. 73:1999;948-957
    • (1999) Journal of Virology , vol.73 , pp. 948-957
    • Robson, N.D.1    Telesnitsky, A.2
  • 54
    • 0030929525 scopus 로고    scopus 로고
    • Creation and removal of embedded ribonucleotides in chromosomal DNA during mammalian Okazaki fragment processing
    • Rumbaugh J.A., Murante R.S., Shi S., Bambara R.A. Creation and removal of embedded ribonucleotides in chromosomal DNA during mammalian Okazaki fragment processing. Journal of Biological Chemistry. 272:1997;22591-22599
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 22591-22599
    • Rumbaugh, J.A.1    Murante, R.S.2    Shi, S.3    Bambara, R.A.4
  • 55
    • 0032582688 scopus 로고    scopus 로고
    • Processing of an HIV replication intermediate by the human DNA replication enzyme FEN1
    • Rumbaugh J.A., Fuentes G.M., Bambara R.A. Processing of an HIV replication intermediate by the human DNA replication enzyme FEN1. Journal of Biological Chemistry. 273:1998;28740-28745
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 28740-28745
    • Rumbaugh, J.A.1    Fuentes, G.M.2    Bambara, R.A.3
  • 56
    • 0035868713 scopus 로고    scopus 로고
    • Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA
    • Sarafianos S.G., Das K., Tantillo C., Clark A.D. Jr., Ding J., Whitcomb J.M., et al. Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA. EMBO Journal. 20:2001;1449-1461
    • (2001) EMBO Journal , vol.20 , pp. 1449-1461
    • Sarafianos, S.G.1    Das, K.2    Tantillo, C.3    Clark Jr., A.D.4    Ding, J.5    Whitcomb, J.M.6
  • 57
    • 0001851755 scopus 로고
    • Inactivation of the RNaseH domain of HIV-1 reverse transcriptase blocks viral infectivity
    • T. Papas (Ed.), Houston, TX: Portfolio Publishing Company.
    • Schatz, O., Cromme, F., Naas, T., Lindemann, D., Gruninger-Leitch, F., Mous, J., & Le Grice, S. F. J. (1990). Inactivation of the RNaseH domain of HIV-1 reverse transcriptase blocks viral infectivity. In T. Papas (Ed.), Oncogenesis and AIDS (pp. 293-303). Houston, TX: Portfolio Publishing Company.
    • (1990) Oncogenesis and AIDS , pp. 293-303
    • Schatz, O.1    Cromme, F.2    Naas, T.3    Lindemann, D.4    Gruninger-Leitch, F.5    Mous, J.6    Le Grice, S.F.J.7
  • 58
    • 0033521113 scopus 로고    scopus 로고
    • Polypurine tract primer generation and utilization by Moloney murine leukemia virus reverse transcriptase
    • Schultz S.J., Zhang M., Kelleher C.D., Champoux J.J. Polypurine tract primer generation and utilization by Moloney murine leukemia virus reverse transcriptase. Journal of Biological Chemistry. 274:1999;34547-34555
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 34547-34555
    • Schultz, S.J.1    Zhang, M.2    Kelleher, C.D.3    Champoux, J.J.4
  • 59
    • 0034644658 scopus 로고    scopus 로고
    • Analysis of plus-strand primer selection, removal, and reutilization by retroviral reverse transcriptases
    • Schultz S.J., Zhang M., Kelleher C.D., Champoux J.J. Analysis of plus-strand primer selection, removal, and reutilization by retroviral reverse transcriptases. Journal of Biological Chemistry. 275:2000;32299-32309
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 32299-32309
    • Schultz, S.J.1    Zhang, M.2    Kelleher, C.D.3    Champoux, J.J.4
  • 60
    • 0037404503 scopus 로고    scopus 로고
    • Specific cleavages by RNase H facilitate initiation of plus-strand RNA synthesis by Moloney murine leukemia virus
    • Schultz S.J., Zhang M., Champoux J.J. Specific cleavages by RNase H facilitate initiation of plus-strand RNA synthesis by Moloney murine leukemia virus. Journal of Virology. 77:2003;5275-5285
    • (2003) Journal of Virology , vol.77 , pp. 5275-5285
    • Schultz, S.J.1    Zhang, M.2    Champoux, J.J.3
  • 61
    • 0036116344 scopus 로고    scopus 로고
    • Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes
    • Seppen J., Rijnberg M., Cooreman M.P., Oude Elferink R.P. Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes. Journal of Hepatology. 36:2002;459-465
    • (2002) Journal of Hepatology , vol.36 , pp. 459-465
    • Seppen, J.1    Rijnberg, M.2    Cooreman, M.P.3    Oude Elferink, R.P.4
  • 62
    • 0019991439 scopus 로고
    • Polypurine tract adjacent to the U3 region of the Rous sarcoma virus genome provides a cis-acting function
    • Sorge J., Hughes S.H. Polypurine tract adjacent to the U3 region of the Rous sarcoma virus genome provides a cis-acting function. Journal of Virology. 43:1982;482-488
    • (1982) Journal of Virology , vol.43 , pp. 482-488
    • Sorge, J.1    Hughes, S.H.2
  • 63
    • 0033596850 scopus 로고    scopus 로고
    • Characterization of (+) strand initiation and termination sequences located at the center of the equine infectious anemia virus genome
    • Stetor S.R., Rausch J.W., Guo M.J., Burnham J.P., Boone L.R., Waring M.J., et al. Characterization of (+) strand initiation and termination sequences located at the center of the equine infectious anemia virus genome. Biochemistry. 38:1999;3656-3667
    • (1999) Biochemistry , vol.38 , pp. 3656-3667
    • Stetor, S.R.1    Rausch, J.W.2    Guo, M.J.3    Burnham, J.P.4    Boone, L.R.5    Waring, M.J.6
  • 64
    • 0030815641 scopus 로고    scopus 로고
    • Effect of RNA secondary structure on RNA cleavage catalyzed by HIV-1 reverse transcriptase
    • Suo Z., Johnson K.A. Effect of RNA secondary structure on RNA cleavage catalyzed by HIV-1 reverse transcriptase. Biochemistry. 36:1997;12468-12476
    • (1997) Biochemistry , vol.36 , pp. 12468-12476
    • Suo, Z.1    Johnson, K.A.2
  • 65
    • 0037384693 scopus 로고    scopus 로고
    • Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction
    • Van Maele B., De Rijck J., De Clercq E., Debyser Z. Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction. Journal of Virology. 77:2003;4685-4694
    • (2003) Journal of Virology , vol.77 , pp. 4685-4694
    • Van Maele, B.1    De Rijck, J.2    De Clercq, E.3    Debyser, Z.4
  • 66
    • 0036682975 scopus 로고    scopus 로고
    • Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo
    • VandenDriessche T., Thorrez L., Naldini L., Follenzi A., Moons L., Berneman Z., et al. Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo. Blood. 100:2002;813-822
    • (2002) Blood , vol.100 , pp. 813-822
    • Vandendriessche, T.1    Thorrez, L.2    Naldini, L.3    Follenzi, A.4    Moons, L.5    Berneman, Z.6
  • 68
    • 0027410067 scopus 로고
    • Enzymatic analysis of two HIV-1 reverse transcriptase mutants with mutations in carboxyl-terminal amino acid residues conserved among retroviral ribonucleases H
    • Volkmann S., Wohrl B.M., Tisdale M., Moelling K. Enzymatic analysis of two HIV-1 reverse transcriptase mutants with mutations in carboxyl-terminal amino acid residues conserved among retroviral ribonucleases H. Journal of Biological Chemistry. 268:1993;2674-2683
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 2674-2683
    • Volkmann, S.1    Wohrl, B.M.2    Tisdale, M.3    Moelling, K.4
  • 69
    • 0034842373 scopus 로고    scopus 로고
    • Identification of a central DNA flap in feline immunodeficiency virus
    • Whitwam T., Peretz M., Poeschla E. Identification of a central DNA flap in feline immunodeficiency virus. Journal of Virology. 75:2001;9407-9414
    • (2001) Journal of Virology , vol.75 , pp. 9407-9414
    • Whitwam, T.1    Peretz, M.2    Poeschla, E.3
  • 70
    • 0025085589 scopus 로고
    • Interaction of HIV-1 ribonuclease H with polypurine tract containing RNA-DNA hybrids
    • Wohrl B.M., Moelling K. Interaction of HIV-1 ribonuclease H with polypurine tract containing RNA-DNA hybrids. Biochemistry. 29:1990;10141-10147
    • (1990) Biochemistry , vol.29 , pp. 10141-10147
    • Wohrl, B.M.1    Moelling, K.2
  • 71
    • 0026196028 scopus 로고
    • Coupling of reverse transcriptase and RNase H during HIV-1 replication
    • Wohrl B.M., Moelling K. Coupling of reverse transcriptase and RNase H during HIV-1 replication. Behring Institute of Mitt. 89:1991;100-107
    • (1991) Behring Institute of Mitt , vol.89 , pp. 100-107
    • Wohrl, B.M.1    Moelling, K.2


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