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Volumn 58, Issue 1, 1998, Pages 135-141

N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells

Author keywords

[No Author keywords available]

Indexed keywords

LOMUSTINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLNITROSOUREA;

EID: 0031975303     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (77)

References (70)
  • 1
    • 0026318356 scopus 로고
    • Participation of p53 protein in the cellular response to DNA damage
    • Kastan, M., Onyekwere, O., Sidransky, D., Vogelstein, B., and Craig, R. W. Participation of p53 protein in the cellular response to DNA damage. Cancer Res., 51: 6304-6311, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6304-6311
    • Kastan, M.1    Onyekwere, O.2    Sidransky, D.3    Vogelstein, B.4    Craig, R.W.5
  • 2
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., and Jacks, T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature (Lond.), 362: 847-849, 1993.
    • (1993) Nature (Lond.) , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 4
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S. W., Ruley, H. E., Jacks, T., and Housman, D. E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74: 957-967, 1993.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 7
    • 0028884525 scopus 로고
    • Cancer therapy and p53
    • Lowe, S. W. Cancer therapy and p53. Curr. Opin. Oncol., 7: 547-553, 1995.
    • (1995) Curr. Opin. Oncol. , vol.7 , pp. 547-553
    • Lowe, S.W.1
  • 10
    • 0021342608 scopus 로고
    • Suppression of cross-link formation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts
    • Brent, T. P. Suppression of cross-link formation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts. Cancer Res., 44: 1887-1892, 1984.
    • (1984) Cancer Res. , vol.44 , pp. 1887-1892
    • Brent, T.P.1
  • 11
    • 0019957212 scopus 로고
    • 3-deoxycytidyl)-2-N′-deoxyguanosyl-ethane, in DNA treated with N,N-bis(2-chloroethyl)-N-nitrosourea (BCNU)
    • 3-deoxycytidyl)-2-N′-deoxyguanosyl)-ethane, in DNA treated with N,N-bis(2-chloroethyl)-N-nitrosourea (BCNU). Cancer Res., 42: 3102-3105, 1982.
    • (1982) Cancer Res. , vol.42 , pp. 3102-3105
    • Tong, W.P.1    Kirk, M.C.2    Ludlum, D.B.3
  • 12
    • 0019126210 scopus 로고
    • DNA cross-linking and monoadduct repair in nitrosourea-treated human cells
    • Erickson, L. C., Laurent, G., Sharkey, N. A., and Kohn, K. W. DNA cross-linking and monoadduct repair in nitrosourea-treated human cells. Nature (Lond.), 288: 727-729, 1980.
    • (1980) Nature (Lond.) , vol.288 , pp. 727-729
    • Erickson, L.C.1    Laurent, G.2    Sharkey, N.A.3    Kohn, K.W.4
  • 13
    • 0022064910 scopus 로고
    • 6-alkylguanine DNA-alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methyl cyclohexyl)-1-nitrosourea
    • 6-alkylguanine DNA-alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methyl cyclohexyl)-1-nitrosourea. Proc. Natl. Acad. Sci. USA, 82: 2985-2989, 1985.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2985-2989
    • Brent, T.P.1    Houghton, P.J.2    Houghton, J.A.3
  • 14
    • 0026087923 scopus 로고
    • Release of 7-alkylguanines from N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosourea-modified DNA by 3-methyladenine DNA glycosylase II
    • Habraken, Y., Carter, C. A., Kirk, M. C., and Ludlum, D. B. Release of 7-alkylguanines from N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosourea-modified DNA by 3-methyladenine DNA glycosylase II. Cancer Res., 51: 499-503, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 499-503
    • Habraken, Y.1    Carter, C.A.2    Kirk, M.C.3    Ludlum, D.B.4
  • 15
    • 0027136120 scopus 로고
    • Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylase
    • Matijasevic, Z., Boosalis, M., Mackay, W., Samson, L., and Ludlum, D. B. Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylase. Proc. Natl. Acad. Sci. USA, 90: 11855-11859, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11855-11859
    • Matijasevic, Z.1    Boosalis, M.2    Mackay, W.3    Samson, L.4    Ludlum, D.B.5
  • 16
    • 0030041960 scopus 로고    scopus 로고
    • Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing
    • Engelward, B. P., Dreslin, A., Christensen, J., Huszar, D., Kurahara, C., and Samson, L. Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing. EMBO J., 15: 945-952, 1996.
    • (1996) EMBO J. , vol.15 , pp. 945-952
    • Engelward, B.P.1    Dreslin, A.2    Christensen, J.3    Huszar, D.4    Kurahara, C.5    Samson, L.6
  • 17
    • 0026750738 scopus 로고
    • Self-destruction and tolerance in resistance of mammalian cells to alkylation damage
    • Karran, P., and Bignami, M. Self-destruction and tolerance in resistance of mammalian cells to alkylation damage. Nucleic Acids Res., 20: 2933-2940, 1992.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 2933-2940
    • Karran, P.1    Bignami, M.2
  • 18
    • 0028533694 scopus 로고
    • DNA damage tolerance, mismatch repair and genome instability
    • Karran, P., and Bignami, M. DNA damage tolerance, mismatch repair and genome instability. BioEssays, 16: 833-839, 1994.
    • (1994) BioEssays , vol.16 , pp. 833-839
    • Karran, P.1    Bignami, M.2
  • 19
    • 0027502938 scopus 로고
    • Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage
    • Branch, P., Aquilina, G., Bignami, M., and Karran, P. Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage. Nature (Lond.), 362: 652-654, 1993.
    • (1993) Nature (Lond.) , vol.362 , pp. 652-654
    • Branch, P.1    Aquilina, G.2    Bignami, M.3    Karran, P.4
  • 20
    • 0027292234 scopus 로고
    • An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
    • Kat, A., Thilly, W. G., Fang, W-H., Longley, M. J., Li, G-M., and Modrich, P. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc. Natl. Acad. Sci. USA, 90: 6424-6428, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6424-6428
    • Kat, A.1    Thilly, W.G.2    Fang, W.-H.3    Longley, M.J.4    Li, G.-M.5    Modrich, P.6
  • 21
    • 0030040312 scopus 로고
    • hMSH2-independent DNA mismatch recognition by human proteins
    • O'Regan, N. E.,. Branch, P., MacPherson, P., and Karran, P. hMSH2-independent DNA mismatch recognition by human proteins. J. Biol. Chem., 271: 1789-1796, 1995.
    • (1995) J. Biol. Chem. , vol.271 , pp. 1789-1796
    • O'Regan, N.E.1    Branch, P.2    MacPherson, P.3    Karran, P.4
  • 23
    • 0029007870 scopus 로고
    • DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines
    • Branch, P., Hampson, R., and Karran, P. DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines. Cancer Res., 55: 2304-2309, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 2304-2309
    • Branch, P.1    Hampson, R.2    Karran, P.3
  • 24
    • 0027936057 scopus 로고
    • Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
    • Koi, M., Umar, A., Chauhan, D., Cherian, S. P., Carethers, J. M., Kunkel, T. A., and Boland, C. R. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res., 54: 4308-4312, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4308-4312
    • Koi, M.1    Umar, A.2    Chauhan, D.3    Cherian, S.P.4    Carethers, J.M.5    Kunkel, T.A.6    Boland, C.R.7
  • 25
    • 0029096730 scopus 로고
    • A hPMS2 mutant cell line is defective in strand-specific mismatch repair
    • Risinger, J. I., Umar, A., Barrett, J. C., and Kunkel, T. A. A hPMS2 mutant cell line is defective in strand-specific mismatch repair. J. Biol. Chem., 270: 18183-18186, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18183-18186
    • Risinger, J.I.1    Umar, A.2    Barrett, J.C.3    Kunkel, T.A.4
  • 26
    • 0030479125 scopus 로고    scopus 로고
    • Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
    • Liu, L., Markowitz, S., and Gerson, S. L. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Cancer Res., 56: 5375-5379, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 5375-5379
    • Liu, L.1    Markowitz, S.2    Gerson, S.L.3
  • 30
    • 0023121208 scopus 로고
    • Transfer of human genes conferring resistance to methylating mutagens but not to UV irradiation and cross-linking agents into Chinese hamster ovary cells
    • Kaina, B., Van Zeeland, A. A., Backendorf, C., Thielmann, H. W., and Van de Putte, P. Transfer of human genes conferring resistance to methylating mutagens but not to UV irradiation and cross-linking agents into Chinese hamster ovary cells. Mol. Cell. Biol., 7: 2024-2030, 1987.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2024-2030
    • Kaina, B.1    Van Zeeland, A.A.2    Backendorf, C.3    Thielmann, H.W.4    Van De Putte, P.5
  • 31
    • 0025194458 scopus 로고
    • 6-methylguanine and 6-thioguanine cytotoxic effects: A cross-resistant phenotype in N-methylnitrosourea-resistant Chinese hamster ovary cells
    • 6-methylguanine and 6-thioguanine cytotoxic effects: a cross-resistant phenotype in N-methylnitrosourea-resistant Chinese hamster ovary cells. Cancer Res., 50: 4248-4253, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 4248-4253
    • Aquilina, G.1    Giammarioli, A.2    Zijno, A.3    Di Muccio, A.4    Dogliotti, E.5    Bignami, M.6
  • 32
    • 0029031825 scopus 로고
    • A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage
    • Aquilina, G., Hess, P., Fiumicino, S., Ceccotti, S., and Bignami, M. A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage. Cancer Res., 55, 2569-2575, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 2569-2575
    • Aquilina, G.1    Hess, P.2    Fiumicino, S.3    Ceccotti, S.4    Bignami, M.5
  • 33
    • 0025924488 scopus 로고
    • 6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents
    • 6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents. Cancer Res., 51: 3367-3372, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 3367-3372
    • Dolan, M.E.1    Mitchell, R.B.2    Mummert, C.3    Moschel, R.C.4    Pegg, A.E.5
  • 34
    • 0030667839 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase expression in acquired resistance to methylating agents in human cells
    • 6-methylguanine-DNA methyltransferase expression in acquired resistance to methylating agents in human cells. J. Biol. Chem., 272: 28596-28606, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28596-28606
    • Hampson, R.1    Humbert, O.2    MacPherson, P.3    Aquilina, G.4    Karran, P.5
  • 36
    • 0028556806 scopus 로고
    • A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype
    • Aquilina, G., Hess, P., Branch, P., Macgeoch, C., Casciano, I., Karran, P., and Bignami, M. A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype. Proc. Natl. Acad. Sci. USA, 91: 8905-8909, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8905-8909
    • Aquilina, G.1    Hess, P.2    Branch, P.3    Macgeoch, C.4    Casciano, I.5    Karran, P.6    Bignami, M.7
  • 37
    • 0025196019 scopus 로고
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc. Natl. Acad. Sci. USA, 87: 5368-5372, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5368-5372
    • Dolan, M.E.1    Moschel, R.C.2    Pegg, A.E.3
  • 40
    • 0024427791 scopus 로고
    • Attenuation of DNA interstrand cross-linking by glutathione
    • Ali-Osman, F. Attenuation of DNA interstrand cross-linking by glutathione. Cancer Res., 49: 5258-5261, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 5258-5261
    • Ali-Osman, F.1
  • 41
    • 0024403939 scopus 로고
    • Denitrosation of 1,3-bis(2-chloroethyl)-1-nitrosourea by class μ glutathione transferases and its role in cellular resistance in rat brain tumor cells
    • Smith, T., Evans, C. G., Doane-Setzer, P., Castro, V. M., Tahir, M. K., and Mannervik, B. Denitrosation of 1,3-bis(2-chloroethyl)-1-nitrosourea by class μ glutathione transferases and its role in cellular resistance in rat brain tumor cells. Cancer Res., 49: 2621-2625, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 2621-2625
    • Smith, T.1    Evans, C.G.2    Doane-Setzer, P.3    Castro, V.M.4    Tahir, M.K.5    Mannervik, B.6
  • 42
    • 0029885315 scopus 로고    scopus 로고
    • Wild-type p53 renders mouse astrocytes resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea despite the absence of a p53-dependent cell cycle arrest
    • Nutt, C. L., Chambers, A. F., and Cairncross, J. G. Wild-type p53 renders mouse astrocytes resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea despite the absence of a p53-dependent cell cycle arrest. Cancer Res., 56: 2748-2751, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2748-2751
    • Nutt, C.L.1    Chambers, A.F.2    Cairncross, J.G.3
  • 43
    • 0026483914 scopus 로고
    • p53 mutations in Raji cells: Characterization and localization relative to other Burkitt's lymphomas
    • Duthu, A., Debuire, B., Romano, J., Ehrhart, J. C., Fiscella, M., May, E., Appella, E., and May, P. p53 mutations in Raji cells: characterization and localization relative to other Burkitt's lymphomas. Oncogene, 7: 2161-2167, 1992.
    • (1992) Oncogene , vol.7 , pp. 2161-2167
    • Duthu, A.1    Debuire, B.2    Romano, J.3    Ehrhart, J.C.4    Fiscella, M.5    May, E.6    Appella, E.7    May, P.8
  • 44
    • 0031021813 scopus 로고    scopus 로고
    • Cloning and characterization of Chinese hamster p53 cDNA
    • Amst.
    • Lee, H., Larner, J. M., and Hamlin, J. L. Cloning and characterization of Chinese hamster p53 cDNA. Gene (Amst.), 184: 177-183, 1997.
    • (1997) Gene , vol.184 , pp. 177-183
    • Lee, H.1    Larner, J.M.2    Hamlin, J.L.3
  • 47
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • Washington DC
    • Rampino, N., Yamamoto, H., Ionov, Y., Li, Y., Sawai, H., Reed, J. C., and Perucho, M. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science (Washington DC), 275: 967-969, 1997.
    • (1997) Science , vol.275 , pp. 967-969
    • Rampino, N.1    Yamamoto, H.2    Ionov, Y.3    Li, Y.4    Sawai, H.5    Reed, J.C.6    Perucho, M.7
  • 48
    • 0022634046 scopus 로고
    • In vivo studies of a novel anticancer agent mitozolomide (NSC 353451) on Lewis lung carcinoma
    • Broggini, M., Erba, E., Morasca, L., Horgan, C., and D' Incalci, M. In vivo studies of a novel anticancer agent mitozolomide (NSC 353451) on Lewis lung carcinoma. Cancer Chemother. Pharmacol., 16: 125-128, 1986.
    • (1986) Cancer Chemother. Pharmacol. , vol.16 , pp. 125-128
    • Broggini, M.1    Erba, E.2    Morasca, L.3    Horgan, C.4    D' Incalci, M.5
  • 49
    • 0023617794 scopus 로고
    • In vitro and in vivo methazolastone-induced DNA damage and repair in L-1210 leukemia sensitive and resistant to chloroethylnitrosoureas
    • Catapano, C. V., Broggini, M., Erba, E., Ponti, M., Mariani, L., Citti, L., and D'Incalci, M. In vitro and in vivo methazolastone-induced DNA damage and repair in L-1210 leukemia sensitive and resistant to chloroethylnitrosoureas. Cancer Res., 47: 4884-4889, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 4884-4889
    • Catapano, C.V.1    Broggini, M.2    Erba, E.3    Ponti, M.4    Mariani, L.5    Citti, L.6    D'Incalci, M.7
  • 50
    • 0025116511 scopus 로고
    • DNA alkylation by haloethylnitrosoureas: Nature of modifications produced and their enzymatic repair or removal
    • Ludlum, D. B. DNA alkylation by haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal. Mutat. Res., 233: 117-126, 1990.
    • (1990) Mutat. Res. , vol.233 , pp. 117-126
    • Ludlum, D.B.1
  • 51
    • 0029144513 scopus 로고
    • Repair of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea-induced damage by mammalian cell extracts
    • Lond.
    • Cappelli, E., Redaelli, A., Rivano, M. E., Abbondandolo, A., and Frosina, G. Repair of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea-induced damage by mammalian cell extracts. Carcinogenesis (Lond.), 16: 2267-2270, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 2267-2270
    • Cappelli, E.1    Redaelli, A.2    Rivano, M.E.3    Abbondandolo, A.4    Frosina, G.5
  • 52
    • 0022510281 scopus 로고
    • Sensitivity to DNA-damaging agents and mutation by UV light in UV-sensitive CHO cells
    • Stefanini, M., Mondello, C., Tessear, L., Capuano, V., Guerra, B. R., and Nuzzo, F. Sensitivity to DNA-damaging agents and mutation by UV light in UV-sensitive CHO cells. Mutat. Res., 174: 155-159, 1986.
    • (1986) Mutat. Res. , vol.174 , pp. 155-159
    • Stefanini, M.1    Mondello, C.2    Tessear, L.3    Capuano, V.4    Guerra, B.R.5    Nuzzo, F.6
  • 53
    • 0026610554 scopus 로고
    • 6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents
    • 6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents. Cancer Res., 52: 32-35, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 32-35
    • Wu, Z.1    Chan, C.-L.2    Eastman, A.3    Bresnick, E.4
  • 54
    • 0029892791 scopus 로고    scopus 로고
    • DNA repair in eukaryotes
    • Wood, R. D. DNA repair in eukaryotes. Annu. Rev. Biochem., 65: 135-167, 1996.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 135-167
    • Wood, R.D.1
  • 55
    • 0029101616 scopus 로고
    • Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer
    • de Wind, N., Dekker, M., Berns, A., Radman, M., and te Riele, H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer. Cell, 82: 321-330, 1995.
    • (1995) Cell , vol.82 , pp. 321-330
    • De Wind, N.1    Dekker, M.2    Berns, A.3    Radman, M.4    Te Riele, H.5
  • 57
    • 0029985445 scopus 로고    scopus 로고
    • Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells
    • Anthoney, D. A., Mcllwrath, A. I., Gallagher, W. M., Edlin, A. R. M., and Brown, R. Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells. Cancer Res., 56: 1374-1381, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 1374-1381
    • Anthoney, D.A.1    Mcllwrath, A.I.2    Gallagher, W.M.3    Edlin, A.R.M.4    Brown, R.5
  • 59
    • 0027494237 scopus 로고
    • p53 oncogene mutations in three human prostate cancer cell lines
    • Carroll, A. G., Voeller, H. J., Sugars, L., and Gelman, E. P. p53 oncogene mutations in three human prostate cancer cell lines. Prostate, 23: 123-134, 1993.
    • (1993) Prostate , vol.23 , pp. 123-134
    • Carroll, A.G.1    Voeller, H.J.2    Sugars, L.3    Gelman, E.P.4
  • 60
    • 0026344260 scopus 로고
    • Analysis of the p53 gene in human uterine carcinoma cell lines
    • Yaginuma, Y., and Westphal, H. Analysis of the p53 gene in human uterine carcinoma cell lines. Cancer Res., 51: 6506-6509, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6506-6509
    • Yaginuma, Y.1    Westphal, H.2
  • 61
    • 0028858101 scopus 로고
    • Human endometrial carcinoma cells release factors which inhibit the growth of normal epithelial cells in culture
    • Albright, C. D., Tsongalis, G. J., Resau, I. H., and Kaufman, D. G. Human endometrial carcinoma cells release factors which inhibit the growth of normal epithelial cells in culture. Cell Biol. Toxicol., 11: 251-261, 1995.
    • (1995) Cell Biol. Toxicol. , vol.11 , pp. 251-261
    • Albright, C.D.1    Tsongalis, G.J.2    Resau, I.H.3    Kaufman, D.G.4
  • 62
    • 0029979313 scopus 로고    scopus 로고
    • DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by Adriamycin
    • Take, Y., Kumano, M., Teraoka, H., Nishimura, S., and Okuyama, A. DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by Adriamycin. Biochem. Biophys. Res. Commun., 221: 207-212, 1996.
    • (1996) Biochem. Biophys. Res. Commun. , vol.221 , pp. 207-212
    • Take, Y.1    Kumano, M.2    Teraoka, H.3    Nishimura, S.4    Okuyama, A.5
  • 66
    • 0028301255 scopus 로고
    • Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability
    • Umar, A., Boyer, J. C., Thomas, D. C., Nguyen, D. C., Risinger, J. I., Boyd, J., Ionov, J., Perucho, M., and Kunkel, T. A. Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J. Biol. Chem., 269: 14367-14370, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14367-14370
    • Umar, A.1    Boyer, J.C.2    Thomas, D.C.3    Nguyen, D.C.4    Risinger, J.I.5    Boyd, J.6    Ionov, J.7    Perucho, M.8    Kunkel, T.A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.