Mutation in the magnesium binding site of hMSH6 disables the hMutSα sliding clamp from translocating along DNA

Journal of Biological Chemistry

Volumn 275, Issue 3, 2000, Pages 2080-2086

  Iaccarino, Ingram ^a,b   Marra, Giancarlo ^a   Dufner, Patrick ^a   Jiricny, Josef ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; DNA BINDING; GENE MUTATION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE PAIR MISMATCH; BINDING SITES; CATALYTIC DOMAIN; CHYMOTRYPSIN; DNA REPAIR; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI PROTEINS; HUMANS; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTS DNA MISMATCH-BINDING PROTEIN; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0034695488     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.3.2080     Document Type: Article

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