The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 25, 2003, Pages 15071-15076

  Cortellino, Salvatore ^a   Turner, David ^a   Masciullo, Valeria ^b   Schepis, Filippo ^a   Albino, Domenico ^a   Daniel, Rene ^a   Skalka, Anna Marie ^a   Meropol, Neal J ^a   Alberti, Christophe ^c   Larue, Lionel ^c   Bellacosa, Alfonso ^a,c  

^a FOX CHASE CANCER CENTER   (United States)

^b TEMPLE UNIVERSITY   (United States)

^c INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DNA; DNA GLYCOSYLTRANSFERASE; ENZYME; FLUOROURACIL; GUANINE; IRINOTECAN; METHYLNITRONITROSOGUANIDINE; PROTEIN MED1; PROTEIN MLH1; THYMINE GLYCOSYLASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CYTOTOXICITY; DNA DAMAGE; EMBRYO; ENZYME ACTIVITY; EXCISION REPAIR; FIBROBLAST; GENE INACTIVATION; GENOTYPE; MISMATCH REPAIR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STEADY STATE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BASE PAIR MISMATCH; BLOTTING, WESTERN; CELL SEPARATION; CELLS, CULTURED; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; ENDODEOXYRIBONUCLEASES; FIBROBLASTS; FLOW CYTOMETRY; G2 PHASE; GENOTYPE; GUANINE; METHYLNITRONITROSOGUANIDINE; MICE; MICE, TRANSGENIC; MITOSIS; MODELS, GENETIC; RETROVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYMINE DNA GLYCOSYLASE; TIME FACTORS;

ANIMALIA; ZIZIPHUS MAURITIANA;

EID: 7044278257     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2334585100     Document Type: Article

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