Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-kinase/AKT in breast cancer cells

Journal of Biological Chemistry

Volumn 274, Issue 45, 1999, Pages 32274-32278

  Altiok, Soner ^a,d   Batt, David ^b   Altiok, Nedret ^b   Papautsky, Anna ^a   Downward, Julian ^c   Roberts, Thomas M ^b   Avrahamt, Hava ^a,e  

^a HARVARD INSTITUTES OF MEDICINE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; GLUTATHIONE TRANSFERASE; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN;

ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0033527577     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.45.32274     Document Type: Article

References (29)

1. Burden, S., Yarden, Y. (1997) Neuron 18, 847-855
2. Altiok, N., Altiok, S., and Changeux, J. P. (1997) EMBO J. 16, 717-725
3. Carpenter, C. L., Cantley, L. C. (1996) Curr. Opin. Cell Biol. 8, 153-158
4. Downward, J. (1998) Science 279, 673-674
5. Coffer, P. J., Jin, J., and Woodgett, J. R. (1998) Biochem J. 335, 1-13
6. Chang, H. W., Aoki, M., Fruman, D., Auger, K. R., Bellacosa, A., Tsichlis, P. N., Cantley, L. C., Roberts, T. M., Vogt, P. K. (1997) Science 276, 1848-1850
7. Miki, Y., Swensen, J., Shattuckeidens, D., Futreal, P. A., Harshman, K., Tavtigian, S., Liu, Q. Y., Cochran, C., Bennett, L. M., Ding, W., Bell, R., Rosenthal, J., Hussey, C., Tran, T., Mcclure, M., Frye, C., Hattier, T., Phelps, R., Haugenstrano, A., Katcher, H., Yakumo, K., Gholami, Z., Shaffer, D., Stone, S., Bayer, S., and Skolnick, M. H. (1994) Science 266, 66-71
8. Futreal, P. A., Liu, Q. Y., Shattuckeidens, D., Cochran, C., Harshman, K., Tavtigian, S., Bennett, L. M., Haugenstrano, A., Swensen, J., Miki, Y., Eddington, K., Mcclure, M., Frye, C., Weaverfeldhaus, J., Ding, W., Gholami, Z., Soderkvist, P., Terry, L., Jhanwar, S., Berchuck, A., Iglehart, J. D., Marks, J., Ballinger, D. G., Barrett, J. C., and Skolnick, M. H. (1994) Science 266, 120-122
9. Easton, D. F., Ford, D., and Bishop, D. T. (1995) Am. J. Hum. Genet. 56, 265-271
10. Ford, D., Easton, D. F., Stratton, M., Narod, S., Goldgar, D., Devilee, P., Bishop, D. T., Weber, B., Lenoir, G., Changclaude, J., Sobol, H., Teare, M. D., Struewing, J., Arason, A., Scherneck, S., Peto, J., Rebbeck, T. R., Tonin, P., Neuhausen, S., Barkardottir, R., Eyfjord, J., Lynch, H., Ponder, B. A. J., Gayther, S. A., Birch,. J. M., and Lindblom, A. (1998) Am. J. Hum. Genet. 62, 676-689
11. Holt, J. T., Thompson, M. E., Szabo, C., Robinson-Benion, C., Arteaga, C. L., King, M. C., and Jensen, R. A. (1996) Nat. Genet. 12, 298-302
12. Somasundaram, K., Zhang, H. B., Zeng, Y. X., Houvras, Y., Peng, Y., Zhang, H. X., Wu, G. S., Licht, J. D., Weber, B. L., and Eldeiry, W. S. (1997) Nature 389, 187-190
13. Lane, T. F., Deng, C. X., Elson, A., Lyu, M. S., Kozak, C. A., and Leder, P (1995) Genes & Dev. 9, 2712-2722
14. Marquis, S. T., Rajan, J. V., Wynahawboris, A., Xu, T. J., Yin, G. Y., Abel, K. J., Weber, B. L., and Chodosh. L. A. (1995) Nat. Genet. 11, 17-26
15. Shao, N., Chai, Y. L., Shyam, E., Reddy, P., and Rao, V. N. (1996) Oncogene 13, 1-7
16. Scully, R., Chen, J. J., Plug, A., Xiao, Y. H., Weaver, D., Feunteun, J., Ashley, T., and Livingston, D. M. (1997) Cell 88, 265-275
17. Scully, R., Chen, J. J., Ochs, R. L., Keegan, K., Hoekstra, M., Feunteun, J., and Livingston, D. M. (1997) Cell 90, 425-435
18. Ruffner, H., and Verma, I. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7138-7143
19. Thomas, J. E., Smith, M., Tonkinson, J. L., Rubinfeld, B., and Polakis, P. (1997) Cell Growth & Differ. 8, 801-809
20. Krane, I. M., and Leder, P. (1996) Oncogene 12, 1781-1788
21. Lewis, G. D., Lofgren, J. A., Mcmurtrey, A. E., Nuijena, A., Fendly, B. M., Bauer, K. D., and Sliwkowski, M. X.: (1996) Cancer Res. 56, 1457-1465
22. Tang, C. K., Perez, C., Grunt, T., Waibel, C., Cho, C., and Lupu, R. (1996) Cancer Res. 56, 3350-3358
23. Hynes, N. E. (1993) Semin. Cancer Biol. 4, 19-26
24. Dudek, H., Datta, S. R., Franke, T. F., Birnbaum, M. J., Yao, R. J., Cooper, G. M., Segal, R A., Kaplan, D. R., and Greenberg, M. E. (1997) Science 275, 661-665
25. Franke, T. F., Yang, S. I., Chan, T. O., Datta, K., Kazlauskaa, A., Morrison, D. K., Kaplan, D. R., and Tsichlis, P. N. (1995) Cell 81, 727-736
26. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu., F., Gotoh, Y., and Greenberg, M. E. (1997) Cell 91, 231-241
27. Alessi, D. R., Caudwell, F. B., Anjelkovic, M., Hemmings, B. A., and Cohen, P. (1996) FEBS Lett. 399, 333-338
28. Rodriguez-Viciana, P., Warne, P. H., Vanhaesebroeck, B., Waterfield, M. D., and Downward, J. (1996) EMBO J 15, 2442-2451
29. Altiok, S., Xu, M., and Spiegelman, B. M. (1997) Genes & Dev. 11, 1987-1998