-
1
-
-
0037064053
-
ATM is activated in response to N-methyl-N′-nitro-N-nitrosoguanidine-induced DNA alkylation
-
Adamson, A.W., Kim, W.J., Shangary, S., Baskaran, R. and Brown, K.D. (2002) ATM is activated in response to N-methyl-N′-nitro-N-nitrosoguanidine-induced DNA alkylation. J. Biol. Chem., 277, 38222-38229.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38222-38229
-
-
Adamson, A.W.1
Kim, W.J.2
Shangary, S.3
Baskaran, R.4
Brown, K.D.5
-
2
-
-
0035161816
-
Functional interactions and signaling properties of mammalian DNA mismatch repair proteins
-
Bellacosa, A. (2001) Functional interactions and signaling properties of mammalian DNA mismatch repair proteins. Cell Death Differ., 8, 1076-1092.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 1076-1092
-
-
Bellacosa, A.1
-
3
-
-
0028784167
-
Microsatellite instability, mismatch repair deficiency and genetic defects in human cancer cell lines
-
Boyer, J.C., Umar, A., Risinger, J.I., Lipford, J.R., Kane, M., Yin, S., Barrett, J.C., Kolodner, R.D. and Kunkel, T.A. (1995) Microsatellite instability, mismatch repair deficiency and genetic defects in human cancer cell lines. Cancer Res., 55, 6063-6070.
-
(1995)
Cancer Res.
, vol.55
, pp. 6063-6070
-
-
Boyer, J.C.1
Umar, A.2
Risinger, J.I.3
Lipford, J.R.4
Kane, M.5
Yin, S.6
Barrett, J.C.7
Kolodner, R.D.8
Kunkel, T.A.9
-
4
-
-
0033083377
-
The human MLH1 cDNA complements DNA mismatch repair defects in Mlh1-deficient mouse embryonic fibroblasts
-
Buermeyer, A.B., Wilson-Van Patten, C., Baker, S.M. and Liskay, R.M. (1999) The human MLH1 cDNA complements DNA mismatch repair defects in Mlh1-deficient mouse embryonic fibroblasts. Cancer Res., 59, 538-541.
-
(1999)
Cancer Res.
, vol.59
, pp. 538-541
-
-
Buermeyer, A.B.1
Wilson-Van Patten, C.2
Baker, S.M.3
Liskay, R.M.4
-
5
-
-
0037171943
-
Methylation tolerance in mismatch repair proficient cells with low MSH2 protein level
-
Claij, N. and Te Riele, H. (2002) Methylation tolerance in mismatch repair proficient cells with low MSH2 protein level. Oncogene, 21, 2873-2879.
-
(2002)
Oncogene
, vol.21
, pp. 2873-2879
-
-
Claij, N.1
Te Riele, H.2
-
6
-
-
0029101616
-
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer
-
de Wind, N., Dekker, M., Berns, A., Radman, M. and te Riele, H. (1995) Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer. Cell, 82, 321-330.
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
De Wind, N.1
Dekker, M.2
Berns, A.3
Radman, M.4
Te Riele, H.5
-
7
-
-
0031984094
-
Mouse models for hereditary nonpolyposis colorectal cancer
-
de Wind, N., Dekker, M., van Rossum, A., van der Valk, M. and te Riele, H. (1998) Mouse models for hereditary nonpolyposis colorectal cancer. Cancer Res., 58, 248-255.
-
(1998)
Cancer Res.
, vol.58
, pp. 248-255
-
-
De Wind, N.1
Dekker, M.2
Van Rossum, A.3
Van der Valk, M.4
Te Riele, H.5
-
8
-
-
0029665878
-
4-methylthymine, or the cisplatin-d(GpG) adduct
-
4-methylthymine, or the cisplatin-d(GpG) adduct. Proc. Natl Acad. Sci. USA, 93, 6443-6447.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6443-6447
-
-
Duckett, D.R.1
Drummond, J.T.2
Murchie, A.I.3
Reardon, J.T.4
Sancar, A.5
Lilley, D.M.6
Modrich, P.7
-
9
-
-
0033607055
-
hMutSα-and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
-
Duckett, D.R., Bronstein, S.M., Taya, Y. and Modrich, P. (1999) hMutSα-and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage. Proc. Natl Acad. Sci. USA, 96, 12384-12388.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12384-12388
-
-
Duckett, D.R.1
Bronstein, S.M.2
Taya, Y.3
Modrich, P.4
-
10
-
-
0037068312
-
CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
-
Esteller, M. (2002) CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene, 21, 5427-5440.
-
(2002)
Oncogene
, vol.21
, pp. 5427-5440
-
-
Esteller, M.1
-
11
-
-
0032723363
-
Signaling mismatch repair in cancer
-
Fishel, R. (1999) Signaling mismatch repair in cancer. Nat. Med., 5, 1239-1241.
-
(1999)
Nat. Med.
, vol.5
, pp. 1239-1241
-
-
Fishel, R.1
-
12
-
-
0034500024
-
DNA mismatch repair and genetic instability
-
Harfe, B.D. and Jinks-Robertson, S. (2000) DNA mismatch repair and genetic instability. Annu. Rev. Genet., 34, 359-399.
-
(2000)
Annu. Rev. Genet.
, vol.34
, pp. 359-399
-
-
Harfe, B.D.1
Jinks-Robertson, S.2
-
13
-
-
0032851842
-
Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
-
Hickman, M.J. and Samson, L.D. (1999) Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc. Natl Acad. Sci. USA, 96, 10764-10769.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10764-10769
-
-
Hickman, M.J.1
Samson, L.D.2
-
14
-
-
0025340001
-
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
-
Holmes, J.J., Clark, S. and Modrich, P. (1990) Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. Proc. Natl Acad. Sci. USA, 87, 5837-5841.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5837-5841
-
-
Holmes, J.J.1
Clark, S.2
Modrich, P.3
-
15
-
-
0031589755
-
6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: Facts and models
-
6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models. Mutat. Res., 381, 227-241.
-
(1997)
Mutat. Res.
, vol.381
, pp. 227-241
-
-
Kaina, B.1
Ziouta, A.2
Ochs, K.3
Coquerelle, T.4
-
16
-
-
0030294633
-
Drug-related killings: A case of mistaken identity
-
Karran, P., and Bignami, M. (1996) Drug-related killings: a case of mistaken identity. Chem. Biol., 3, 875-879.
-
(1996)
Chem. Biol.
, vol.3
, pp. 875-879
-
-
Karran, P.1
Bignami, M.2
-
17
-
-
0032524104
-
Landscaping the cancer terrain
-
Kinzler, K.W. and Vogelstein, B. (1998) Landscaping the cancer terrain. Science, 280, 1036-1037.
-
(1998)
Science
, vol.280
, pp. 1036-1037
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
18
-
-
0035868951
-
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci
-
Kleczkowska, H.E., Marra, G., Lettieri, T. and Jiricny, J. (2001) hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci. Genes Dev., 15, 724-736.
-
(2001)
Genes Dev.
, vol.15
, pp. 724-736
-
-
Kleczkowska, H.E.1
Marra, G.2
Lettieri, T.3
Jiricny, J.4
-
19
-
-
0027936057
-
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
-
published erratum appears in Cancer Res., 1995, 55, 201
-
Koi, M., Umar, A., Chauhan, D.P., Cherian, S.P., Carethers, J.M., Kunkel, T.A. and Boland, C.R. (1994) Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation (published erratum appears in Cancer Res., 1995, 55, 201). Cancer Res., 54, 4308-4312.
-
(1994)
Cancer Res.
, vol.54
, pp. 4308-4312
-
-
Koi, M.1
Umar, A.2
Chauhan, D.P.3
Cherian, S.P.4
Carethers, J.M.5
Kunkel, T.A.6
Boland, C.R.7
-
20
-
-
0033065150
-
Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15
-
Lettieri, T., Marra, G., Aquilina, G., Bignami, M., Crompton, N.E., Palombo, F. and Jiricny, J. (1999) Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15. Carcinogenesis, 20, 373-382.
-
(1999)
Carcinogenesis
, vol.20
, pp. 373-382
-
-
Lettieri, T.1
Marra, G.2
Aquilina, G.3
Bignami, M.4
Crompton, N.E.5
Palombo, F.6
Jiricny, J.7
-
21
-
-
0022037404
-
Apurinic sites as mutagenic intermediates
-
Loeb, L.A. (1985) Apurinic sites as mutagenic intermediates. Cell, 40, 483-484.
-
(1985)
Cell
, vol.40
, pp. 483-484
-
-
Loeb, L.A.1
-
22
-
-
0035361301
-
Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC)
-
Loukola, A., Eklin, K., Laiho, P., Salovaara, R., Kristo, P., Jarvinen, H., Mecklin, J.P., Launonen, V. and Aaltonen, L.A. (2001) Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC). Cancer Res., 61, 4545-4549.
-
(2001)
Cancer Res.
, vol.61
, pp. 4545-4549
-
-
Loukola, A.1
Eklin, K.2
Laiho, P.3
Salovaara, R.4
Kristo, P.5
Jarvinen, H.6
Mecklin, J.P.7
Launonen, V.8
Aaltonen, L.A.9
-
23
-
-
0036528298
-
Focus on colon cancer
-
Markowitz, S.D., Dawson, D.M., Willis, J. and Willson, J.K. (2002) Focus on colon cancer. Cancer Cell, 1, 233-236.
-
(2002)
Cancer Cell
, vol.1
, pp. 233-236
-
-
Markowitz, S.D.1
Dawson, D.M.2
Willis, J.3
Willson, J.K.4
-
24
-
-
0035912811
-
Tolerance of human MSH2+/- lymphoblastoid cells to the methylating agent temozolomide
-
Marra, G. et al. (2001) Tolerance of human MSH2+/- lymphoblastoid cells to the methylating agent temozolomide. Proc. Natl Acad. Sci. USA, 98, 7164-7169.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7164-7169
-
-
Marra, G.1
-
25
-
-
0036007071
-
Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer
-
Nystrom-Lahti, M. et al. (2002) Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer. Genes Chromosomes Cancer, 33, 160-167.
-
(2002)
Genes Chromosomes Cancer
, vol.33
, pp. 160-167
-
-
Nystrom-Lahti, M.1
-
26
-
-
0036849432
-
Checking on the fork: The DNA-replication stress-response pathway
-
Osborn, A.J., Elledge, S.J. and Zou, L. (2002) Checking on the fork: the DNA-replication stress-response pathway. Trends Cell Biol., 12, 509-516.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 509-516
-
-
Osborn, A.J.1
Elledge, S.J.2
Zou, L.3
-
27
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull, T.T., Rogakou, E.P., Yamazaki, V., Kirchgessner, C.U., Gellert, M. and Bonner, W.M. (2000) A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol., 10, 886-895.
-
(2000)
Curr. Biol.
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
28
-
-
0035101436
-
DNA mismatch repair and cancer
-
Peltomaki, P. (2001) DNA mismatch repair and cancer. Mutat. Res., 488, 77-85.
-
(2001)
Mutat. Res.
, vol.488
, pp. 77-85
-
-
Peltomaki, P.1
-
29
-
-
0033527450
-
Identification of hMutLβ, a Heterodimer of hMLH1 and hPMS1
-
Räschle, M., Marra, G., Nyström-Lahti, M., Schär, P. and Jiricny, J. (1999) Identification of hMutLβ, a Heterodimer of hMLH1 and hPMS1. J. Biol. Chem., 274, 32368-32375.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32368-32375
-
-
Räschle, M.1
Marra, G.2
Nyström-Lahti, M.3
Schär, P.4
Jiricny, J.5
-
30
-
-
0036531895
-
Histone H2A variants H2AX and H2AZ
-
Redon, C., Pilch, D., Rogakou, E., Sedelnikova, O., Newrock, K. and Bonner, W. (2002) Histone H2A variants H2AX and H2AZ. Curr. Opin. Genet. Dev., 12, 162-169.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 162-169
-
-
Redon, C.1
Pilch, D.2
Rogakou, E.3
Sedelnikova, O.4
Newrock, K.5
Bonner, W.6
-
31
-
-
0032527610
-
Single gene complementation of the hPMS2 defect in HEC-I-A endometrial carcinoma cells
-
Risinger, J.I., Umar, A., Glaab, W.E., Tindall, K.R., Kunkel, T.A. and Barrett, J.C. (1998) Single gene complementation of the hPMS2 defect in HEC-I-A endometrial carcinoma cells. Cancer Res., 58, 2978-2981.
-
(1998)
Cancer Res.
, vol.58
, pp. 2978-2981
-
-
Risinger, J.I.1
Umar, A.2
Glaab, W.E.3
Tindall, K.R.4
Kunkel, T.A.5
Barrett, J.C.6
-
32
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
33
-
-
0032915375
-
Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations
-
Shcherbakova, P.V. and Kunkel, T.A. (1999) Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations. Mol. Cell. Biol., 19, 3177-3183.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3177-3183
-
-
Shcherbakova, P.V.1
Kunkel, T.A.2
-
34
-
-
0035132696
-
Inactivation of DNA mismatch repair by increased expression of yeast MLH1
-
Shcherbakova, P.V., Hall, M.C., Lewis, M.S., Bennett, S.E., Martin, K.J., Bushel, P.R., Afshari, C.A. and Kunkel, T.A. (2001) Inactivation of DNA mismatch repair by increased expression of yeast MLH1. Mol. Cell. Biol., 21, 940-951.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 940-951
-
-
Shcherbakova, P.V.1
Hall, M.C.2
Lewis, M.S.3
Bennett, S.E.4
Martin, K.J.5
Bushel, P.R.6
Afshari, C.A.7
Kunkel, T.A.8
-
35
-
-
0031932659
-
Growth suppression mediated by transfection of wild-type hMLH1 in human cancer cells expressing endogenous truncated hMLH1 protein
-
Shin, K.H., Han, H.J. and Park, J.G. (1998) Growth suppression mediated by transfection of wild-type hMLH1 in human cancer cells expressing endogenous truncated hMLH1 protein. Int. J. Oncol., 12, 609-615.
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 609-615
-
-
Shin, K.H.1
Han, H.J.2
Park, J.G.3
-
36
-
-
0025777777
-
Heteroduplex repair in extracts of human HeLa cells
-
Thomas, D.C., Roberts, J.D. and Kunkel, T.A. (1991) Heteroduplex repair in extracts of human HeLa cells. J. Biol. Chem., 266, 3744-3751.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 3744-3751
-
-
Thomas, D.C.1
Roberts, J.D.2
Kunkel, T.A.3
-
37
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts, R.S., Brumbaugh, K.M., Williams, J.M., Sarkaria, J.N., Cliby, W.A., Shieh, S.Y., Taya, Y., Prives, C. and Abraham, R.T. (1999) A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev., 13, 152-157.
-
(1999)
Genes Dev.
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
38
-
-
0036143918
-
Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system
-
Trojan, J., Zeuzem, S., Randolph, A., Hemmerle, C., Brieger, A., Raedle, J., Plotz, G., Jiricny, J. and Marra, G. (2002) Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system. Gastroenterology, 122, 211-219.
-
(2002)
Gastroenterology
, vol.122
, pp. 211-219
-
-
Trojan, J.1
Zeuzem, S.2
Randolph, A.3
Hemmerle, C.4
Brieger, A.5
Raedle, J.6
Plotz, G.7
Jiricny, J.8
Marra, G.9
-
39
-
-
0033168064
-
Apoptosis induced by overexpression of hMSH2 or hMLH1
-
Zhang, H., Richards, B., Wilson, T., Lloyd, M., Cranston, A., Thorburn, A., Fishel, R. and Meuth, M. (1999) Apoptosis induced by overexpression of hMSH2 or hMLH1. Cancer Res., 59, 3021-3027.
-
(1999)
Cancer Res.
, vol.59
, pp. 3021-3027
-
-
Zhang, H.1
Richards, B.2
Wilson, T.3
Lloyd, M.4
Cranston, A.5
Thorburn, A.6
Fishel, R.7
Meuth, M.8
|