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Volumn 53, Issue 5, 2005, Pages 418-427

Toll-like receptor expression and function in airway epithelial cells

Author keywords

Airway epithelial cells; Inflammatory lung disease; Toll like receptors

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BROPIRIMINE; DOUBLE STRANDED DNA; IMIQUIMOD; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LOXORIBINE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 30944461373     PISSN: 0004069X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (71)

References (95)
  • 1
    • 2342535902 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and Toll-like receptor 2 as well as Toll-like receptor 5
    • Adamo R., Sokol S., Soong G., Gomez M. I. and Prince A. (2004): Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and Toll-like receptor 2 as well as Toll-like receptor 5. Am. J. Respir. Cell Mol. Biol., 30, 627-634.
    • (2004) Am. J. Respir. Cell Mol. Biol. , vol.30 , pp. 627-634
    • Adamo, R.1    Sokol, S.2    Soong, G.3    Gomez, M.I.4    Prince, A.5
  • 2
    • 0037111078 scopus 로고    scopus 로고
    • Human Toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of Gram-negative infections
    • Agnese D. M., Galvano J. E., Hahm S. J., Coyle S. M., Corbett S. A., Galvano S. E. and Lowry S. F. (2002): Human Toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of Gram-negative infections. J. Infect. Dis., 186, 1522-1525.
    • (2002) J. Infect. Dis. , vol.186 , pp. 1522-1525
    • Agnese, D.M.1    Galvano, J.E.2    Hahm, S.J.3    Coyle, S.M.4    Corbett, S.A.5    Galvano, S.E.6    Lowry, S.F.7
  • 3
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira S. and Hemmi H. (2003): Recognition of pathogen-associated molecular patterns by TLR family. Immunol. Lett., 85, 85-95.
    • (2003) Immunol. Lett. , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 4
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou L., Holt A. C., Medzhitov R. and Flavell R. A. (2001): Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature, 413, 732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 6
    • 3843106031 scopus 로고    scopus 로고
    • Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways
    • Bachar O., Adner M., Uddman R. and Cardell L. O. (2004): Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways. Eur. J. Immunol., 34, 1196-1207.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1196-1207
    • Bachar, O.1    Adner, M.2    Uddman, R.3    Cardell, L.O.4
  • 7
    • 0037596457 scopus 로고    scopus 로고
    • A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses
    • Bartfai T., Behrens M. M., Gaidarova S., Pemberton J., Shivanyuk A. and Rebek J. Jr. (2003): A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses. Proc. Natl. Acad. Sci. USA, 100, 7971-7976.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7971-7976
    • Bartfai, T.1    Behrens, M.M.2    Gaidarova, S.3    Pemberton, J.4    Shivanyuk, A.5    Rebek Jr., J.6
  • 10
    • 0034703072 scopus 로고    scopus 로고
    • CD14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium
    • Becker M. N., Diamond G., Verghese M. W. and Randell S. H. (2000): CD14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium. J. Biol. Chem., 275, 29731-29736.
    • (2000) J. Biol. Chem. , vol.275 , pp. 29731-29736
    • Becker, M.N.1    Diamond, G.2    Verghese, M.W.3    Randell, S.H.4
  • 13
    • 0033861419 scopus 로고    scopus 로고
    • The interleukin-1 receptor//Toll-like receptor superfamily: Signal generators for pro-inflammatory interleukins and microbial products
    • Bowie A. and O'Neill L. A. (2000): The interleukin-1 receptor//Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products. J. Leukoc. Biol., 67, 508-514.
    • (2000) J. Leukoc. Biol. , vol.67 , pp. 508-514
    • Bowie, A.1    O'Neill, L.A.2
  • 17
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow J. C., Young D. W., Golenbock D. T., Christ W. J. and Gusovsky F. (1999): Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem., 274, 10689-10692.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 18
    • 5444254408 scopus 로고    scopus 로고
    • Toll-like receptors in the pathogenesis of human disease
    • Cook D. N., Pisetsky D. S. and Schwartz D. A. (2004): Toll-like receptors in the pathogenesis of human disease. Nat. Immunol., 5, 975-979.
    • (2004) Nat. Immunol. , vol.5 , pp. 975-979
    • Cook, D.N.1    Pisetsky, D.S.2    Schwartz, D.A.3
  • 19
    • 0034644474 scopus 로고    scopus 로고
    • Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
    • Deng L., Wang C., Spencer E., Yang L., Braun A., You J., Slaughter C., Pickart C. and Chen Z. J. (2000): Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell, 103, 351-361.
    • (2000) Cell , vol.103 , pp. 351-361
    • Deng, L.1    Wang, C.2    Spencer, E.3    Yang, L.4    Braun, A.5    You, J.6    Slaughter, C.7    Pickart, C.8    Chen, Z.J.9
  • 20
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold S. S., Kaisho T., Hemmi H., Akira S. and Reis e Sousa C. (2004): Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science, 303, 1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis E Sousa, C.5
  • 24
    • 0025774776 scopus 로고
    • Drosophila Toll and IL-1 receptor
    • Gay N. J. and Keith F. J. (1991): Drosophila Toll and IL-1 receptor. Nature, 351, 355-356.
    • (1991) Nature , vol.351 , pp. 355-356
    • Gay, N.J.1    Keith, F.J.2
  • 26
    • 0037087255 scopus 로고    scopus 로고
    • Toll-like receptor 4-MD-2 complex mediates the signal transduction induced by flavolipin, an amino acid-containing lipid unique to Flavobacterium meningosepticum
    • Gomi K., Kawasaki K., Kawai Y., Shiozaki M. and Nishijima M. (2002): Toll-like receptor 4-MD-2 complex mediates the signal transduction induced by flavolipin, an amino acid-containing lipid unique to Flavobacterium meningosepticum. J. Immunol., 168, 2939-2943.
    • (2002) J. Immunol. , vol.168 , pp. 2939-2943
    • Gomi, K.1    Kawasaki, K.2    Kawai, Y.3    Shiozaki, M.4    Nishijima, M.5
  • 29
    • 0037097672 scopus 로고    scopus 로고
    • Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
    • Guillot L., Balloy V., McCormack F. X., Golenbock D. T., Chignard M. and Si-Tahar M. (2002): Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J. Immunol., 168, 5989-5992.
    • (2002) J. Immunol. , vol.168 , pp. 5989-5992
    • Guillot, L.1    Balloy, V.2    McCormack, F.X.3    Golenbock, D.T.4    Chignard, M.5    Si-Tahar, M.6
  • 30
    • 14044267522 scopus 로고    scopus 로고
    • Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus
    • Guillot L., Le Goffic R., Bloch S., Escriou N., Akira S., Chignard M. and Si-Tahar M. (2005): Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J. Biol. Chem., 280, 5571-5580.
    • (2005) J. Biol. Chem. , vol.280 , pp. 5571-5580
    • Guillot, L.1    Le Goffic, R.2    Bloch, S.3    Escriou, N.4    Akira, S.5    Chignard, M.6    Si-Tahar, M.7
  • 31
    • 1642494708 scopus 로고    scopus 로고
    • Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: Evidence for an intracellular compartmentalization of TLR4
    • Guillot L., Medjane S., Le-Barillec K., Balloy V., Danel C., Chignard M. and Si-Tahar M. (2004): Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4. J. Biol. Chem., 279, 2712-2718.
    • (2004) J. Biol. Chem. , vol.279 , pp. 2712-2718
    • Guillot, L.1    Medjane, S.2    Le-Barillec, K.3    Balloy, V.4    Danel, C.5    Chignard, M.6    Si-Tahar, M.7
  • 37
    • 0036784269 scopus 로고    scopus 로고
    • The epithelial cell cytoskeleton and intracellular trafficking. V. Polarized compartmentalization of antigen processing and Toll-like receptor signaling in intestinal epithelial cells
    • Hershberg R. M. (2002): The epithelial cell cytoskeleton and intracellular trafficking. V. Polarized compartmentalization of antigen processing and Toll-like receptor signaling in intestinal epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol., 283, G833-839.
    • (2002) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.283
    • Hershberg, R.M.1
  • 38
    • 0346366980 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2
    • Hertz C. J., Wu Q., Porter E. M., Zhang Y. J., Weismuller K. H., Godowski P. J., Ganz T., Randell S. H. and Modlin R. L. (2003): Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2. J. Immunol., 171, 6820-6826.
    • (2003) J. Immunol. , vol.171 , pp. 6820-6826
    • Hertz, C.J.1    Wu, Q.2    Porter, E.M.3    Zhang, Y.J.4    Weismuller, K.H.5    Godowski, P.J.6    Ganz, T.7    Randell, S.H.8    Modlin, R.L.9
  • 40
    • 0035555301 scopus 로고    scopus 로고
    • TIRAP: An adapter molecule in the Toll signaling pathway
    • Horng T., Barton G. M. and Medzhitov R. (2001): TIRAP: an adapter molecule in the Toll signaling pathway. Nat. Immunol., 2, 835-841.
    • (2001) Nat. Immunol. , vol.2 , pp. 835-841
    • Horng, T.1    Barton, G.M.2    Medzhitov, R.3
  • 43
    • 0035889228 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
    • Kawai T., Takeuchi O., Fujita T., Inoue J., Muhlradt P. F., Sato S., Hoshino K. and Akira S. (2001): Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol., 167, 5887-5894.
    • (2001) J. Immunol. , vol.167 , pp. 5887-5894
    • Kawai, T.1    Takeuchi, O.2    Fujita, T.3    Inoue, J.4    Muhlradt, P.F.5    Sato, S.6    Hoshino, K.7    Akira, S.8
  • 44
    • 0034777579 scopus 로고    scopus 로고
    • Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12
    • Krug A., Towarowski A., Britsch S., Rothenfusser S., Hornung V., Bals R., Giese T., Engelmann H., Endres S., Krieg A. M. and Hartmann G. (2001): Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12. Eur. J. Immunol., 31, 3026-3037.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3026-3037
    • Krug, A.1    Towarowski, A.2    Britsch, S.3    Rothenfusser, S.4    Hornung, V.5    Bals, R.6    Giese, T.7    Engelmann, H.8    Endres, S.9    Krieg, A.M.10    Hartmann, G.11
  • 48
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre B., Nicolas E., Michaut L., Reichhart J. M. and Hoffmann J. A. (1996): The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell, 86, 973-983.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 49
    • 0033794461 scopus 로고    scopus 로고
    • A novel polymorphism in the Toll-like receptor 2 gene and its potential association with staphylococcal infection
    • Lorenz E., Mira J. P., Cornish K. L., Arbour N. C. and Schwartz D. A. (2000): A novel polymorphism in the Toll-like receptor 2 gene and its potential association with staphylococcal infection. Infect. Immun., 68, 6398-6401.
    • (2000) Infect. Immun. , vol.68 , pp. 6398-6401
    • Lorenz, E.1    Mira, J.P.2    Cornish, K.L.3    Arbour, N.C.4    Schwartz, D.A.5
  • 57
    • 0034650427 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex
    • Ohashi K., Burkart V., Flohe S. and Kolb H. (2000): Cutting edge: heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex. J. Immunol., 164, 558-561.
    • (2000) J. Immunol. , vol.164 , pp. 558-561
    • Ohashi, K.1    Burkart, V.2    Flohe, S.3    Kolb, H.4
  • 59
    • 0036449063 scopus 로고    scopus 로고
    • Signal transduction pathways activated by the IL-1 receptor/Toll-like receptor superfamily
    • O'Neill L. A. (2002): Signal transduction pathways activated by the IL-1 receptor/Toll-like receptor superfamily. Curr. Top Microbiol. Immunol., 270, 47-61.
    • (2002) Curr. Top Microbiol. Immunol. , vol.270 , pp. 47-61
    • O'Neill, L.A.1
  • 60
    • 0037505362 scopus 로고    scopus 로고
    • The Toll-IL-1 receptor adaptor family grows to five members
    • O'Neill L. A., Fitzgerald K. A. and Bowie A. G. (2003): The Toll-IL-1 receptor adaptor family grows to five members. Trends Immunol., 24, 286-290.
    • (2003) Trends Immunol. , vol.24 , pp. 286-290
    • O'Neill, L.A.1    Fitzgerald, K.A.2    Bowie, A.G.3
  • 61
    • 0031801957 scopus 로고    scopus 로고
    • Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants
    • O'Neill L. A. and Greene C. (1998): Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants. J. Leukoc. Biol., 63, 650-657.
    • (1998) J. Leukoc. Biol. , vol.63 , pp. 650-657
    • O'Neill, L.A.1    Greene, C.2
  • 62
    • 0037320451 scopus 로고    scopus 로고
    • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
    • Oshiumi H., Matsumoto M., Funami K., Akazawa T. and Seya T. (2003): TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat. Immunol., 4, 161-167.
    • (2003) Nat. Immunol. , vol.4 , pp. 161-167
    • Oshiumi, H.1    Matsumoto, M.2    Funami, K.3    Akazawa, T.4    Seya, T.5
  • 63
    • 0345991221 scopus 로고    scopus 로고
    • TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to Toll-like receptor 4 TICAM-1 that induces interferon-beta
    • Oshiumi H., Sasai M., Shida K., Fujita T., Matsumoto M. and Seya T. (2003): TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to Toll-like receptor 4 TICAM-1 that induces interferon-beta. J. Biol. Chem., 278, 49751-49762.
    • (2003) J. Biol. Chem. , vol.278 , pp. 49751-49762
    • Oshiumi, H.1    Sasai, M.2    Shida, K.3    Fujita, T.4    Matsumoto, M.5    Seya, T.6
  • 64
    • 0034460078 scopus 로고    scopus 로고
    • Co-operative induction of pro-inflammatory signaling by Toll-like receptors
    • Ozinsky A., Smith K. D., Hume D. and Underhill D. M. (2000): Co-operative induction of pro-inflammatory signaling by Toll-like receptors. J. Endotoxin Res., 6, 393-396.
    • (2000) J. Endotoxin Res. , vol.6 , pp. 393-396
    • Ozinsky, A.1    Smith, K.D.2    Hume, D.3    Underhill, D.M.4
  • 69
    • 0035800883 scopus 로고    scopus 로고
    • Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via Toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation
    • Sasu S., LaVerda D., Qureshi N., Golenbock D. T. and Beasley D. (2001): Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via Toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation. Circ. Res., 89, 244-250.
    • (2001) Circ. Res. , vol.89 , pp. 244-250
    • Sasu, S.1    Laverda, D.2    Qureshi, N.3    Golenbock, D.T.4    Beasley, D.5
  • 70
    • 0038205797 scopus 로고    scopus 로고
    • Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha secretion are down-regulated by lung collectin surfactant protein A
    • Sato M., Sano H., Iwaki D., Kudo K., Konishi M., Takahashi H., Takahashi T., Imaizumi H., Asai Y. and Kuroki Y. (2003): Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha secretion are down-regulated by lung collectin surfactant protein A. J. Immunol., 171, 417-425.
    • (2003) J. Immunol. , vol.171 , pp. 417-425
    • Sato, M.1    Sano, H.2    Iwaki, D.3    Kudo, K.4    Konishi, M.5    Takahashi, H.6    Takahashi, T.7    Imaizumi, H.8    Asai, Y.9    Kuroki, Y.10
  • 71
    • 0035971087 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinases p42/44, p38, and stress-activated protein kinases in myelo-monocytic cells by Treponema lipoteichoic acid
    • Schroder N. W., Pfeil D., Opitz B., Michelsen K. S., Amberger J., Zahringer U., Gobel U. B. and Schumann R. R. (2001): Activation of mitogen-activated protein kinases p42/44, p38, and stress-activated protein kinases in myelo-monocytic cells by Treponema lipoteichoic acid. J. Biol. Chem., 276, 9713-9719.
    • (2001) J. Biol. Chem. , vol.276 , pp. 9713-9719
    • Schroder, N.W.1    Pfeil, D.2    Opitz, B.3    Michelsen, K.S.4    Amberger, J.5    Zahringer, U.6    Gobel, U.B.7    Schumann, R.R.8
  • 72
    • 0036255408 scopus 로고    scopus 로고
    • TLR4 and LPS hyporesponsiveness in humans
    • Schwartz D. A. (2002): TLR4 and LPS hyporesponsiveness in humans. Int. J. Hyg. Environ. Health, 205, 221-227.
    • (2002) Int. J. Hyg. Environ. Health , vol.205 , pp. 221-227
    • Schwartz, D.A.1
  • 74
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an IKK-related pathway
    • Sharma S., tenOever B. R., Grandvaux N., Zhou G. P., Lin R. and Hiscott J. (2003): Triggering the interferon antiviral response through an IKK-related pathway. Science, 300, 1148-1151.
    • (2003) Science , vol.300 , pp. 1148-1151
    • Sharma, S.1    Tenoever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5    Hiscott, J.6
  • 75
    • 0344010115 scopus 로고    scopus 로고
    • Toll-like receptor 4 plays no role in susceptibility of mice to Mycobacterium tuberculosis infection
    • Shim T. S., Turner O. C. and Orme I. M. (2003): Toll-like receptor 4 plays no role in susceptibility of mice to Mycobacterium tuberculosis infection, Tuberculosis, 83, 367-371.
    • (2003) Tuberculosis , vol.83 , pp. 367-371
    • Shim, T.S.1    Turner, O.C.2    Orme, I.M.3
  • 76
    • 0034681434 scopus 로고    scopus 로고
    • Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways
    • Slack J. L., Schooley K., Bonnert T. P., Mitcham J. L., Qwarnstrom E. E., Sims J. E. and Dower S. K. (2000): Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways. J. Biol. Chem., 275, 4670-4678.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4670-4678
    • Slack, J.L.1    Schooley, K.2    Bonnert, T.P.3    Mitcham, J.L.4    Qwarnstrom, E.E.5    Sims, J.E.6    Dower, S.K.7
  • 77
    • 2942532924 scopus 로고    scopus 로고
    • TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells
    • Soong G., Reddy B., Sokol S., Adamo R. and Prince A. (2004): TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells. J. Clin. Invest., 113, 1482-1489.
    • (2004) J. Clin. Invest. , vol.113 , pp. 1482-1489
    • Soong, G.1    Reddy, B.2    Sokol, S.3    Adamo, R.4    Prince, A.5
  • 79
    • 0742324860 scopus 로고    scopus 로고
    • TLR signaling pathways
    • Takeda K. and Akira S. (2004): TLR signaling pathways. Semin. Immunol., 16, 3-9.
    • (2004) Semin. Immunol. , vol.16 , pp. 3-9
    • Takeda, K.1    Akira, S.2
  • 84
    • 0035929634 scopus 로고    scopus 로고
    • Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium
    • Walsh D. E., Greene C. M., Carroll T. P., Taggart C. C., Gallagher P. M., O'Neill S. J. and McElvaney N. G. (2001): Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium. J. Biol. Chem., 276, 35494-35499.
    • (2001) J. Biol. Chem. , vol.276 , pp. 35494-35499
    • Walsh, D.E.1    Greene, C.M.2    Carroll, T.P.3    Taggart, C.C.4    Gallagher, P.M.5    O'Neill, S.J.6    McElvaney, N.G.7
  • 85
  • 86
    • 0141483491 scopus 로고    scopus 로고
    • Airway epithelia regulate expression of human beta-defensin 2 through Toll-like receptor 2
    • Wang X., Zhang Z., Louboutin J. P., Moser C., Weiner D. J. and Wilson J. M. (2003): Airway epithelia regulate expression of human beta-defensin 2 through Toll-like receptor 2. FASEB J., 17, 1727-1729.
    • (2003) FASEB J. , vol.17 , pp. 1727-1729
    • Wang, X.1    Zhang, Z.2    Louboutin, J.P.3    Moser, C.4    Weiner, D.J.5    Wilson, J.M.6
  • 87
    • 0026582215 scopus 로고
    • Anti-endotoxin monoclonal antibodies - A second look
    • Wenzel R. P. (1992): Anti-endotoxin monoclonal antibodies - a second look. N. Engl. J. Med., 326, 1151-1153.
    • (1992) N. Engl. J. Med. , vol.326 , pp. 1151-1153
    • Wenzel, R.P.1
  • 89
    • 0038664380 scopus 로고    scopus 로고
    • The role of Toll-like receptor 2 in microbial disease and immunity
    • Wetzler L. M. (2003): The role of Toll-like receptor 2 in microbial disease and immunity. Vaccine, 21 (suppl. 2), S55-60.
    • (2003) Vaccine , vol.21 , Issue.SUPPL. 2
    • Wetzler, L.M.1
  • 92
    • 0037114185 scopus 로고    scopus 로고
    • Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
    • Yamamoto M., Sato S., Mori K., Hoshino K., Takeuchi O., Takeda K. and Akira S. (2002): Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J. Immunol., 169, 6668-6672.
    • (2002) J. Immunol. , vol.169 , pp. 6668-6672
    • Yamamoto, M.1    Sato, S.2    Mori, K.3    Hoshino, K.4    Takeuchi, O.5    Takeda, K.6    Akira, S.7
  • 93
    • 0346157331 scopus 로고    scopus 로고
    • TIR domain-containing adaptors define the specificity of TLR signaling
    • Yamamoto M., Takeda K. and Akira S. (2004): TIR domain-containing adaptors define the specificity of TLR signaling. Mol. Immunol., 40, 861-868.
    • (2004) Mol. Immunol. , vol.40 , pp. 861-868
    • Yamamoto, M.1    Takeda, K.2    Akira, S.3


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