Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections

Journal of Infectious Diseases

Volumn 186, Issue 10, 2002, Pages 1522-1525

  Agnese, Doreen M ^a,b   Calvano, Jacqueline E ^a   Hahm, Sae J ^a   Coyle, Susette M ^a   Corbett, Siobhan A ^a   Calvano, Steve E ^a   Lowry, Stephen F ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

ADULT; AGED; ARTICLE; BACTERIAL INFECTION; BACTERIAL MUTATION; BACTERIUM CULTURE; CONTROLLED STUDY; CRITICAL ILLNESS; FEMALE; GENE MUTATION; GENETIC POLYMORPHISM; GRAM NEGATIVE INFECTION; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOMES RESEARCH; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD14; DISEASE SUSCEPTIBILITY; DROSOPHILA PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MUTATION; POLYMORPHISM, GENETIC; RECEPTORS, CELL SURFACE; RISK FACTORS; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; VARIATION (GENETICS);

EID: 0037111078     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/344893     Document Type: Article

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