Targeting endogenous inhibitors of apoptosis for treatment of cancer, stroke and multiple sclerosis

Expert Opinion on Therapeutic Targets

Volumn 8, Issue 3, 2004, Pages 241-253

  Holčík, Martin ^a  

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

Author keywords

Antisense; Apoptosis; Caspase; Gene therapy; Inhibitor of apoptosis (IAP); Oligonucleotides; Tumour

Indexed keywords

ADENOVIRUS VECTOR; ANTISENSE OLIGONUCLEOTIDE; BETA INTERFERON; CASPASE; CASPASE INHIBITOR; CISPLATIN; COMPLEMENTARY DNA; DOXORUBICIN; INHIBITOR OF APOPTOSIS PROTEIN; NAVELBINE; OXIDOPAMINE; POLYPHENYLUREA DERIVATIVE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; UREA DERIVATIVE;

APOPTOSIS; BACULOVIRUS; CANCER; CELL DEATH; CLINICAL TRIAL; DOWN REGULATION; DRUG MECHANISM; DRUG SENSITIZATION; DRUG TARGETING; ENZYME BINDING; ENZYME INHIBITION; GENE OVEREXPRESSION; GENETIC CONSERVATION; GENETIC DISTANCE; HUMAN; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; NUCLEOTIDE REPEAT; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW; STROKE;

ANIMALS; APOPTOSIS; CEREBROVASCULAR ACCIDENT; DRUG DELIVERY SYSTEMS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MULTIPLE SCLEROSIS; NEOPLASMS;

EID: 3042839751     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.8.3.241     Document Type: Review

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