Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 21, 1997, Pages 11657-11662

  Du, Yansheng ^a   Bales, Kelly R ^a   Dodel, Richard C ^b,c   Hamilton Byrd, Elizabeth ^a   Horn, Jeffrey W ^a   Czilli, Dan L ^a   Simmons, Linda K ^a   Ni, Binhui ^a   Paul, Steven M ^a,c  

^a ELI LILLY AND COMPANY   (United States)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; CALCIUM ION; CYCLOHEXIMIDE; CYSTEINE PROTEINASE; DACTINOMYCIN; DIZOCILPINE; GLUTAMIC ACID; INTERLEUKIN 1BETA CONVERTING ENZYME; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROTEIN SYNTHESIS INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CEREBELLUM; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; GRANULE CELL; NERVE CELL CULTURE; NEUROTOXICITY; NEUROTRANSMISSION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELLS, CULTURED; CEREBELLUM; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; CYTOSOL; ENZYME ACTIVATION; ENZYME PRECURSORS; GLUTAMIC ACID; KINETICS; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; OLIGOPEPTIDES; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUTAMATE;

EID: 0030868345     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.21.11657     Document Type: Article

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