-
1
-
-
0032931328
-
Epidemiology of NSAID induced gastrointestinal complications
-
Singh G, Triadafilopoulos G. Epidemiology of NSAID induced gastrointestinal complications. J Rheumatol 1999;26(Suppl 56):18-24.
-
(1999)
J Rheumatol
, vol.26
, Issue.56 SUPPL.
, pp. 18-24
-
-
Singh, G.1
Triadafilopoulos, G.2
-
2
-
-
0036178106
-
Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases
-
Kessler FK, Kessler MR, Auyeung DJ, Ritter JK. Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases. Drug Metab Dispos 2002;30:324-330.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 324-330
-
-
Kessler, F.K.1
Kessler, M.R.2
Auyeung, D.J.3
Ritter, J.K.4
-
3
-
-
0032853122
-
Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib
-
Paulson SK, Engel L, Reitz B, et al. Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib. Drug Metab Dispos 1999;27:1133-1142.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 1133-1142
-
-
Paulson, S.K.1
Engel, L.2
Reitz, B.3
-
4
-
-
0026709167
-
Nonsteroidal anti-inflammatory drug toxicosis in dogs and cats: 240 Cases (1989-1990)
-
Jones RD, Baynes RE, Nimitz CT. Nonsteroidal anti-inflammatory drug toxicosis in dogs and cats: 240 Cases (1989-1990). J Am Vet Med Assoc 1992;201:475-477.
-
(1992)
J Am Vet Med Assoc
, vol.201
, pp. 475-477
-
-
Jones, R.D.1
Baynes, R.E.2
Nimitz, C.T.3
-
5
-
-
0019465394
-
Pharmacokinetics of naproxen in the dog
-
Frey HH, Rieh B. Pharmacokinetics of naproxen in the dog. Am J Vet Res 1981;42:1615-1617.
-
(1981)
Am J Vet Res
, vol.42
, pp. 1615-1617
-
-
Frey, H.H.1
Rieh, B.2
-
6
-
-
4043124909
-
Adverse drug event reports at the United States Food and Drug Administration Center for Veterinary Medicine
-
Hampshire VA, Doddy FM, Post LO, et al. Adverse drug event reports at the United States Food And Drug Administration Center for Veterinary Medicine. J Am Vet Med Assoc 2004;225:533-536.
-
(2004)
J Am Vet Med Assoc
, vol.225
, pp. 533-536
-
-
Hampshire, V.A.1
Doddy, F.M.2
Post, L.O.3
-
7
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971;231:232-235.
-
(1971)
Nat New Biol
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
8
-
-
0022623897
-
Physiology and pharmacology of prostaglandins
-
Konturek SJ, Pawlik W. Physiology and pharmacology of prostaglandins. Dig Dis Sci 1986;31:6S-19S.
-
(1986)
Dig Dis Sci
, vol.31
-
-
Konturek, S.J.1
Pawlik, W.2
-
10
-
-
0028034970
-
Cyclooxygenase-2 is associated with the macula densa of the rat kidney and increases with salt restriction
-
Harris RC, McKanna JA, Akai Y, et al. Cyclooxygenase-2 is associated with the macula densa of the rat kidney and increases with salt restriction. J Clin Invest 1994;94:2504-2510.
-
(1994)
J Clin Invest
, vol.94
, pp. 2504-2510
-
-
Harris, R.C.1
McKanna, J.A.2
Akai, Y.3
-
11
-
-
0030017042
-
Characterization of prostaglandin G/H synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts
-
Kargman S, Charleson S, Cartwright M, et al. Characterization of prostaglandin G/H synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts. Gastroenterology 1996;111:445-454.
-
(1996)
Gastroenterology
, vol.111
, pp. 445-454
-
-
Kargman, S.1
Charleson, S.2
Cartwright, M.3
-
12
-
-
0031717446
-
Cyclooxygenases as the principal targets for the actions of NSAIDs
-
Smith TJ. Cyclooxygenases as the principal targets for the actions of NSAIDs. Rheum Dis Clin North Am 1998;24:501-523.
-
(1998)
Rheum Dis Clin North Am
, vol.24
, pp. 501-523
-
-
Smith, T.J.1
-
13
-
-
3042576460
-
Determination of expression of cyclooxygenase-1 and -2 isozymes in canine tissues and their differential sensitivity to nonsteroidal anti-inflammatory drugs
-
Wilson JE, Chandrasekharan NV, Westover KD, et al. Determination of expression of cyclooxygenase-1 and -2 isozymes in canine tissues and their differential sensitivity to nonsteroidal anti-inflammatory drugs. Am J Vet Res 2004;65:810-818.
-
(2004)
Am J Vet Res
, vol.65
, pp. 810-818
-
-
Wilson, J.E.1
Chandrasekharan, N.V.2
Westover, K.D.3
-
14
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
-
USA
-
Xie WL, Chipman JG, Robertson DL, et al. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 1991;88:2692-2696.
-
(1991)
Proc Natl Acad Sci
, vol.88
, pp. 2692-2696
-
-
Xie, W.L.1
Chipman, J.G.2
Robertson, D.L.3
-
15
-
-
0031766198
-
Localization of cyclooxygenase-2 and regulation of its mRNA expression in gastric ulcers in rats
-
Takahashi S, Shigeta J, Inoue H, et al. Localization of cyclooxygenase-2 and regulation of its mRNA expression in gastric ulcers in rats. Am J Physiol 1998;275:G1137-G1145.
-
(1998)
Am J Physiol
, vol.275
-
-
Takahashi, S.1
Shigeta, J.2
Inoue, H.3
-
16
-
-
0027076645
-
Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide
-
Lee SH, Soyoola E, Chanmugam P, et al. Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J Biol Chem 1992;267:25934-25938.
-
(1992)
J Biol Chem
, vol.267
, pp. 25934-25938
-
-
Lee, S.H.1
Soyoola, E.2
Chanmugam, P.3
-
17
-
-
0033610923
-
Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA
-
Newton R, Seybold J, Kuitert LM, et al. Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA. J Biol Chem 1998;273:32312-32321.
-
(1998)
J Biol Chem
, vol.273
, pp. 32312-32321
-
-
Newton, R.1
Seybold, J.2
Kuitert, L.M.3
-
18
-
-
0036308753
-
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
-
Qi Z, Hao CM, Langenbach RI, et al. Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II. J Clin Invest 2002;110:61-69.
-
(2002)
J Clin Invest
, vol.110
, pp. 61-69
-
-
Qi, Z.1
Hao, C.M.2
Langenbach, R.I.3
-
19
-
-
0032737556
-
Cyclo-oxygenase-2: Pharmacology, physiology, biochemistry and relevance to NSAID therapy
-
Mitchell JA, Warner TD. Cyclo-oxygenase-2: Pharmacology, physiology, biochemistry and relevance to NSAID therapy. Br J Pharmacol 1999;128:1121-1132.
-
(1999)
Br J Pharmacol
, vol.128
, pp. 1121-1132
-
-
Mitchell, J.A.1
Warner, T.D.2
-
20
-
-
0034041077
-
Basic biology and clinical application of specific cyclooxygenase-2 inhibitors
-
Crofford LJ, Lipsky PE, Brooks P, et al. Basic biology and clinical application of specific cyclooxygenase-2 inhibitors. Arthritis Rheum 2000;43:4-13.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 4-13
-
-
Crofford, L.J.1
Lipsky, P.E.2
Brooks, P.3
-
21
-
-
0033791318
-
Cyclooxygenases: Structural, cellular, and molecular biology
-
Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: Structural, cellular, and molecular biology. Annu Rev Biochem 2000;69:145-182.
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 145-182
-
-
Smith, W.L.1
DeWitt, D.L.2
Garavito, R.M.3
-
22
-
-
0028926813
-
New insights into the mode of action of anti-inflammatory drugs
-
Vane JR, Botting RM. New insights into the mode of action of anti-inflammatory drugs. Inflamm Res 1995;44:1-10.
-
(1995)
Inflamm Res
, vol.44
, pp. 1-10
-
-
Vane, J.R.1
Botting, R.M.2
-
23
-
-
0026744831
-
Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles
-
Sirois J, Richards JS. Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles. J Biol Chem 1992;267:6382-6388.
-
(1992)
J Biol Chem
, vol.267
, pp. 6382-6388
-
-
Sirois, J.1
Richards, J.S.2
-
24
-
-
0028009093
-
The x-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
-
Picot D, Loll PJ, Garavito RM. The x-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature 1994;367:243-249.
-
(1994)
Nature
, vol.367
, pp. 243-249
-
-
Picot, D.1
Loll, P.J.2
Garavito, R.M.3
-
25
-
-
0033031331
-
COX-2 inhibitors
-
Hawkey CJ. COX-2 inhibitors. Lancet 1999;353:307-314.
-
(1999)
Lancet
, vol.353
, pp. 307-314
-
-
Hawkey, C.J.1
-
26
-
-
0030461132
-
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
-
Kurumbail RG, Stevens AM, Gierse JK, et al. Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature 1996;384:644-648.
-
(1996)
Nature
, vol.384
, pp. 644-648
-
-
Kurumbail, R.G.1
Stevens, A.M.2
Gierse, J.K.3
-
27
-
-
0028147767
-
Structure of the human cyclo-oxygenase-2 gene
-
Appleby SB, Ristimaki A, Neilson K, et al. Structure of the human cyclo-oxygenase-2 gene. Biochem J 1994;302(Pt 3):723-727.
-
(1994)
Biochem J
, vol.302
, Issue.3 PART
, pp. 723-727
-
-
Appleby, S.B.1
Ristimaki, A.2
Neilson, K.3
-
28
-
-
0026588059
-
Prostaglandin endoperoxide synthase gene structure: Identification of the transcriptional start site and 5′-flanking regulatory sequences
-
Kraemer SA, Meade EA, DeWitt DL. Prostaglandin endoperoxide synthase gene structure: Identification of the transcriptional start site and 5′-flanking regulatory sequences. Arch Biochem Biophys 1992;293:391-400.
-
(1992)
Arch Biochem Biophys
, vol.293
, pp. 391-400
-
-
Kraemer, S.A.1
Meade, E.A.2
DeWitt, D.L.3
-
29
-
-
1542297649
-
Selective cyclooxygenase-2 inhibitors: Similarities and differences
-
Brune K, Hinz B. Selective cyclooxygenase-2 inhibitors: Similarities and differences. Scand J Rheumatol 2004;33:1-6.
-
(2004)
Scand J Rheumatol
, vol.33
, pp. 1-6
-
-
Brune, K.1
Hinz, B.2
-
30
-
-
0037379761
-
Characterization of celecoxib and valdecoxib binding to cyclooxygenase
-
Hood WF, Gierse JK, Isakson PC, et al. Characterization of celecoxib and valdecoxib binding to cyclooxygenase. Mol Pharmacol 2003;63:870-877.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 870-877
-
-
Hood, W.F.1
Gierse, J.K.2
Isakson, P.C.3
-
31
-
-
0034699923
-
Nomenclature for COX-2 inhibitors
-
Vane JR, Warner TD. Nomenclature for COX-2 inhibitors. Lancet 2000;356:1373-1374.
-
(2000)
Lancet
, vol.356
, pp. 1373-1374
-
-
Vane, J.R.1
Warner, T.D.2
-
32
-
-
0012762429
-
Dose escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of COX189 in healthy subjects
-
Scott G, Rordorf C, Blood P, et al. Dose escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of COX189 in healthy subjects. Ann Rheum Dis 2002;61(Suppl 1):242.
-
(2002)
Ann Rheum Dis
, vol.61
, Issue.1 SUPPL.
, pp. 242
-
-
Scott, G.1
Rordorf, C.2
Blood, P.3
-
33
-
-
2042475404
-
Pharmacokinetics and metabolism of lumiracoxib in healthy male subjects
-
Mangold JB, Gu H, Rodriguez LC, et al. Pharmacokinetics and metabolism of lumiracoxib in healthy male subjects. Drug Metab Dispos 2004;32:566-571.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 566-571
-
-
Mangold, J.B.1
Gu, H.2
Rodriguez, L.C.3
-
34
-
-
1842536146
-
In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in dogs with experimentally induced synovitis
-
McCann ME, Andersen DR, Zhang D, et al. In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in dogs with experimentally induced synovitis. Am J Vet Res 2004;65:503-512.
-
(2004)
Am J Vet Res
, vol.65
, pp. 503-512
-
-
McCann, M.E.1
Andersen, D.R.2
Zhang, D.3
-
35
-
-
0034754976
-
In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats
-
Brideau C, Van SC, Chan CC. In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats. Am J Vet Res 2001;62:1755-1760.
-
(2001)
Am J Vet Res
, vol.62
, pp. 1755-1760
-
-
Brideau, C.1
Van, S.C.2
Chan, C.C.3
-
36
-
-
0033936426
-
In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs
-
Kay-Mugford P, Benn SJ, LaMarre J, Conlon P. In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs. Am J Vet Res 2000;61:802-810.
-
(2000)
Am J Vet Res
, vol.61
, pp. 802-810
-
-
Kay-Mugford, P.1
Benn, S.J.2
LaMarre, J.3
Conlon, P.4
-
37
-
-
0033665248
-
Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: A randomized, controlled trial
-
Leese PT, Hubbard RC, Karim A, et al. Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: A randomized, controlled trial. J Clin Pharmacol 2000;40:124-132.
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 124-132
-
-
Leese, P.T.1
Hubbard, R.C.2
Karim, A.3
-
38
-
-
0036846480
-
In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs
-
Jones CJ, Streppa HK, Harmon BG, Budsberg SC. In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs. Am J Vet Res 2002;63:1527-1531.
-
(2002)
Am J Vet Res
, vol.63
, pp. 1527-1531
-
-
Jones, C.J.1
Streppa, H.K.2
Harmon, B.G.3
Budsberg, S.C.4
-
39
-
-
20444487741
-
In vivo effects of carprofen, deracoxib, and etodolac on whole blood, gastric mucosal and synovial fluid prostaglandin synthesis in dogs with osteoarthritis
-
Sessions JK, Agnello KA, Reynolds LR, Budsberg SC. In vivo effects of carprofen, deracoxib, and etodolac on whole blood, gastric mucosal and synovial fluid prostaglandin synthesis in dogs with osteoarthritis. Am J Vet Res 2005;66:812-817.
-
(2005)
Am J Vet Res
, vol.66
, pp. 812-817
-
-
Sessions, J.K.1
Agnello, K.A.2
Reynolds, L.R.3
Budsberg, S.C.4
-
40
-
-
0027944075
-
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
-
USA
-
Seibert K, Zhang Y, Leahy K, et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994;91:12013-12017.
-
(1994)
Proc Natl Acad Sci
, vol.91
, pp. 12013-12017
-
-
Seibert, K.1
Zhang, Y.2
Leahy, K.3
-
41
-
-
0031473814
-
Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production
-
Zhang Y, Shaffer A, Portanova J, et al. Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production. J Pharmacol Exp Ther 1997;283:1069-1075.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 1069-1075
-
-
Zhang, Y.1
Shaffer, A.2
Portanova, J.3
-
42
-
-
0027516402
-
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions
-
Futaki N, Yoshikawa K, Hamasaka Y, et al. NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. Gen Pharmacol 1993;24:105-110.
-
(1993)
Gen Pharmacol
, vol.24
, pp. 105-110
-
-
Futaki, N.1
Yoshikawa, K.2
Hamasaka, Y.3
-
43
-
-
0033601089
-
Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: A randomized controlled trial
-
Simon LS, Weaver AL, Graham DY, et al. Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: A randomized controlled trial. JAMA 1999;282:1921-1928.
-
(1999)
JAMA
, vol.282
, pp. 1921-1928
-
-
Simon, L.S.1
Weaver, A.L.2
Graham, D.Y.3
-
44
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
-
VIGOR Study Group
-
Bombardier C, Laine L, Reicin A, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 2000;343:1520-1528.
-
(2000)
N Engl J Med
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
-
45
-
-
0034746312
-
The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure
-
Stock JL, Shinjo K, Burkhardt J, et al. The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure. J Clin Invest 2001;107:325-331.
-
(2001)
J Clin Invest
, vol.107
, pp. 325-331
-
-
Stock, J.L.1
Shinjo, K.2
Burkhardt, J.3
-
46
-
-
0035081365
-
Prostaglandins and cyclooxygenases [correction of cycloxygenases] in the spinal cord
-
Vanegas H, Schaible HG. Prostaglandins and cyclooxygenases [correction of cycloxygenases] in the spinal cord. Prog Neurobiol 2001;64:327-363.
-
(2001)
Prog Neurobiol
, vol.64
, pp. 327-363
-
-
Vanegas, H.1
Schaible, H.G.2
-
47
-
-
13144260638
-
Pharmacological analysis of cyclooxygenase-1 in inflammation
-
USA
-
Smith CJ, Zhang Y, Koboldt CM, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci USA 1998;95:13313-13318.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 13313-13318
-
-
Smith, C.J.1
Zhang, Y.2
Koboldt, C.M.3
-
48
-
-
0030597962
-
Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation
-
Beiche F, Scheuerer S, Brune K, et al. Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation. FEBS Lett 1996;390:165-169.
-
(1996)
FEBS Lett
, vol.390
, pp. 165-169
-
-
Beiche, F.1
Scheuerer, S.2
Brune, K.3
-
49
-
-
0031394120
-
Cyclooxygenase-2 in the spinal cord: Localization and regulation after a peripheral inflammatory stimulus
-
Goppelt-Struebe M, Beiche F. Cyclooxygenase-2 in the spinal cord: Localization and regulation after a peripheral inflammatory stimulus. Adv Exp Med Biol 1997;433:213-216.
-
(1997)
Adv Exp Med Biol
, vol.433
, pp. 213-216
-
-
Goppelt-Struebe, M.1
Beiche, F.2
-
50
-
-
0031463351
-
Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability
-
Willingale HL, Gardiner NJ, McLymont N, et al. Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability. Br J Pharmacol 1997;122:1593-1604.
-
(1997)
Br J Pharmacol
, vol.122
, pp. 1593-1604
-
-
Willingale, H.L.1
Gardiner, N.J.2
McLymont, N.3
-
51
-
-
0027290813
-
Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
-
Yamagata K, Andreasson KI, Kaufmann WE, et al. Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids. Neuron 1993;11:371-386.
-
(1993)
Neuron
, vol.11
, pp. 371-386
-
-
Yamagata, K.1
Andreasson, K.I.2
Kaufmann, W.E.3
-
52
-
-
0031051604
-
Cyclooxygenase-2 expression during rat neocortical development and in Rett syndrome
-
Kaufmann WE, Worley PF, Taylor CV, et al. Cyclooxygenase-2 expression during rat neocortical development and in Rett syndrome. Brain Dev 1997;19:25-34.
-
(1997)
Brain Dev
, vol.19
, pp. 25-34
-
-
Kaufmann, W.E.1
Worley, P.F.2
Taylor, C.V.3
-
53
-
-
0242484486
-
Blood brain barrier penetration of oral rofecoxib, a potent and selective cyclooxygenase-2 inhibitor in dogs
-
Buvanendran A, Kroin J, Luk P, et al. Blood brain barrier penetration of oral rofecoxib, a potent and selective cyclooxygenase-2 inhibitor in dogs. Anesthesiology 2002;97:A465.
-
(2002)
Anesthesiology
, vol.97
-
-
Buvanendran, A.1
Kroin, J.2
Luk, P.3
-
54
-
-
0012929426
-
Central nervous system penetration of oral rofecoxib, a potent and selective cyclooxygenase-2 inhibitor in dogs
-
Buvanendran A, Kroin J, Luk P, et al. Central nervous system penetration of oral rofecoxib, a potent and selective cyclooxygenase-2 inhibitor in dogs. Anesthesiology 2001;95:A868.
-
(2001)
Anesthesiology
, vol.95
-
-
Buvanendran, A.1
Kroin, J.2
Luk, P.3
-
55
-
-
0016695111
-
Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis
-
Robinson DR, Tashjian AH Jr, Levine L. Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis. J Clin Invest 1975;56:1181-1188.
-
(1975)
J Clin Invest
, vol.56
, pp. 1181-1188
-
-
Robinson, D.R.1
Tashjian Jr., A.H.2
Levine, L.3
-
57
-
-
0036064137
-
Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants
-
Hardy MM, Seibert K, Manning PT, et al. Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants. Arthritis Rheum 2002;46:1789-1803.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1789-1803
-
-
Hardy, M.M.1
Seibert, K.2
Manning, P.T.3
-
58
-
-
0026563366
-
Influence of prostaglandins on DNA and matrix synthesis in growth plate chondrocytes
-
O'Keefe RJ, Crabb ID, Puzas JE, Rosier RN. Influence of prostaglandins on DNA and matrix synthesis in growth plate chondrocytes. J Bone Miner Res 1992;7:397-404.
-
(1992)
J Bone Miner Res
, vol.7
, pp. 397-404
-
-
O'Keefe, R.J.1
Crabb, I.D.2
Puzas, J.E.3
Rosier, R.N.4
-
59
-
-
0020842196
-
Effect of prostaglandin E2 on adult pig articular cartilage slices in culture
-
Fulkerson JP, Damiano P. Effect of prostaglandin E2 on adult pig articular cartilage slices in culture. Clin Orthop Relat Res Oct 1983;179:266-269.
-
(1983)
Clin Orthop Relat Res Oct
, vol.179
, pp. 266-269
-
-
Fulkerson, J.P.1
Damiano, P.2
-
60
-
-
0029785026
-
Expression of cyclooxygenase-2 in human and an animal model of rheumatoid arthritis
-
Kang RY, Freire-Moar J, Sigal E, Chu CQ. Expression of cyclooxygenase-2 in human and an animal model of rheumatoid arthritis. Br J Rheumatol 1996;35:711-718.
-
(1996)
Br J Rheumatol
, vol.35
, pp. 711-718
-
-
Kang, R.Y.1
Freire-Moar, J.2
Sigal, E.3
Chu, C.Q.4
-
61
-
-
0030945182
-
Superinduction of cyclooxygenase-2 activity in human osteoarthritis- affected cartilage. Influence of nitric oxide
-
Amin AR, Attur M, Patel RN, et al. Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide. J Clin Invest 1997;99:1231-1237.
-
(1997)
J Clin Invest
, vol.99
, pp. 1231-1237
-
-
Amin, A.R.1
Attur, M.2
Patel, R.N.3
-
62
-
-
0019418005
-
The synovial prostaglandin system in chronic inflammatory arthritis: Differential effects of steroidal and nonsteroidal anti-inflammatory drugs
-
Bombardieri S, Cattani P, Ciabattoni G, et al. The synovial prostaglandin system in chronic inflammatory arthritis: Differential effects of steroidal and nonsteroidal anti-inflammatory drugs. Br J Pharmacol 1981;73:893-901.
-
(1981)
Br J Pharmacol
, vol.73
, pp. 893-901
-
-
Bombardieri, S.1
Cattani, P.2
Ciabattoni, G.3
-
63
-
-
0033000873
-
Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes
-
Blanco FJ, Guitian R, Moreno J, et al. Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes. J Rheumatol 1999;26:1366-1373.
-
(1999)
J Rheumatol
, vol.26
, pp. 1366-1373
-
-
Blanco, F.J.1
Guitian, R.2
Moreno, J.3
-
64
-
-
0034971296
-
Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets
-
Pelletier JP, Martel-Pelletier J, Abramson SB. Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets. Arthritis Rheum 2001;44:1237-1247.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1237-1247
-
-
Pelletier, J.P.1
Martel-Pelletier, J.2
Abramson, S.B.3
-
65
-
-
0034181857
-
Nitric oxide metabolite production in the cranial cruciate ligament, synovial membrane, and articular cartilage of dogs with cranial cruciate ligament rupture
-
Spreng D, Sigrist N, Jungi T, et al. Nitric oxide metabolite production in the cranial cruciate ligament, synovial membrane, and articular cartilage of dogs with cranial cruciate ligament rupture. Am J Vet Res 2000;61:530-536.
-
(2000)
Am J Vet Res
, vol.61
, pp. 530-536
-
-
Spreng, D.1
Sigrist, N.2
Jungi, T.3
-
66
-
-
0035292929
-
Endogenous nitric oxide production in canine osteoarthritis: Detection in urine, serum, and synovial fluid specimens
-
Spreng D, Sigrist N, Schweighauser A, et al. Endogenous nitric oxide production in canine osteoarthritis: Detection in urine, serum, and synovial fluid specimens. Vet Surg 2001;30:191-199.
-
(2001)
Vet Surg
, vol.30
, pp. 191-199
-
-
Spreng, D.1
Sigrist, N.2
Schweighauser, A.3
-
67
-
-
0031864605
-
Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase
-
Pelletier JP, Jovanovic D, Fernandes JC, et al. Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase. Arthritis Rheum 1998;41:1275-1286.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1275-1286
-
-
Pelletier, J.P.1
Jovanovic, D.2
Fernandes, J.C.3
-
68
-
-
0031093312
-
Nitric oxide production by equine articular cells in vitro
-
Frean SP, Bryant CE, Froling IL, et al. Nitric oxide production by equine articular cells in vitro. Equine Vet J 1997;29:98-102.
-
(1997)
Equine Vet J
, vol.29
, pp. 98-102
-
-
Frean, S.P.1
Bryant, C.E.2
Froling, I.L.3
-
69
-
-
0003504049
-
Cyclooxygenase regulates angiogenesis induced by colon cancer cells
-
Tsujii M, Kawano S, Tsuji S, et al. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998;93:705-716.
-
(1998)
Cell
, vol.93
, pp. 705-716
-
-
Tsujii, M.1
Kawano, S.2
Tsuji, S.3
-
70
-
-
0033624548
-
Effect of prostaglandin E1 on vascular endothelial growth factor production by human macrophages and colon cancer cells
-
Bamba H, Ota S, Kato A, et al. Effect of prostaglandin E1 on vascular endothelial growth factor production by human macrophages and colon cancer cells. J Exp Clin Cancer Res 2000;19:219-223.
-
(2000)
J Exp Clin Cancer Res
, vol.19
, pp. 219-223
-
-
Bamba, H.1
Ota, S.2
Kato, A.3
-
71
-
-
0034083354
-
The effect of NSAIDs and a COX-2 specific inhibitor on Helicobacter pylori-induced PGE2 and HGF in human gastric fibroblasts
-
Takahashi M, Katayama Y, Takada H, et al. The effect of NSAIDs and a COX-2 specific inhibitor on Helicobacter pylori-induced PGE2 and HGF in human gastric fibroblasts. Aliment Pharmacol Ther 2000;14(Suppl 1):44-49.
-
(2000)
Aliment Pharmacol Ther
, vol.14
, Issue.1 SUPPL.
, pp. 44-49
-
-
Takahashi, M.1
Katayama, Y.2
Takada, H.3
-
72
-
-
0034029780
-
Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants
-
Majima M, Hayashi I, Muramatsu M, et al. Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants. Br J Pharmacol 2000;130:641-649.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 641-649
-
-
Majima, M.1
Hayashi, I.2
Muramatsu, M.3
-
73
-
-
0028803728
-
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
-
Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995;83:493-501.
-
(1995)
Cell
, vol.83
, pp. 493-501
-
-
Tsujii, M.1
DuBois, R.N.2
-
74
-
-
0027371123
-
Altered eicosanoid levels in human colon cancer
-
Rigas B, Goldman IS, Levine L. Altered eicosanoid levels in human colon cancer. J Lab Clin Med 1993;122:518-523.
-
(1993)
J Lab Clin Med
, vol.122
, pp. 518-523
-
-
Rigas, B.1
Goldman, I.S.2
Levine, L.3
-
75
-
-
0030044692
-
Modulating effect of amount and types of dietary fat on colonic mucosal phospholipase A2, phosphatidylinositol-specific phospholipase C activities, and cyclooxygenase metabolite formation during different stages of colon tumor promotion in male F344 rats
-
Rao CV, Simi B, Wynn TT, et al. Modulating effect of amount and types of dietary fat on colonic mucosal phospholipase A2, phosphatidylinositol-specific phospholipase C activities, and cyclooxygenase metabolite formation during different stages of colon tumor promotion in male F344 rats. Cancer Res 1996;56:532-537.
-
(1996)
Cancer Res
, vol.56
, pp. 532-537
-
-
Rao, C.V.1
Simi, B.2
Wynn, T.T.3
-
76
-
-
0027993458
-
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
-
Eberhart CE, Coffey RJ, Radhika A, et al. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994;107:1183-1188.
-
(1994)
Gastroenterology
, vol.107
, pp. 1183-1188
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
-
77
-
-
0029899153
-
Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: Evidence for a transcriptional effect
-
USA
-
Kutchera W, Jones DA, Matsunami N, et al. Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: Evidence for a transcriptional effect. Proc Natl Acad Sci USA 1996;93:4816-4820.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 4816-4820
-
-
Kutchera, W.1
Jones, D.A.2
Matsunami, N.3
-
78
-
-
0036634569
-
Cyclooxygenase-2 expression in spontaneous intestinal neoplasia of domestic dogs
-
McEntee MF, Cates JM, Neilsen N. Cyclooxygenase-2 expression in spontaneous intestinal neoplasia of domestic dogs. Vet Pathol 2002;39:428-436.
-
(2002)
Vet Pathol
, vol.39
, pp. 428-436
-
-
McEntee, M.F.1
Cates, J.M.2
Neilsen, N.3
-
79
-
-
0034107624
-
Expression of cyclooxygenase-2 in transitional cell carcinoma of the urinary bladder in dogs
-
Khan KN, Knapp DW, Denicola DB, Harris RK. Expression of cyclooxygenase-2 in transitional cell carcinoma of the urinary bladder in dogs. Am J Vet Res 2000;61:478-481.
-
(2000)
Am J Vet Res
, vol.61
, pp. 478-481
-
-
Khan, K.N.1
Knapp, D.W.2
Denicola, D.B.3
Harris, R.K.4
-
80
-
-
0032170955
-
Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas
-
Hida T, Yatabe Y, Achiwa H, et al. Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res 1998;58:3761-3764.
-
(1998)
Cancer Res
, vol.58
, pp. 3761-3764
-
-
Hida, T.1
Yatabe, Y.2
Achiwa, H.3
-
81
-
-
0141854494
-
Expression of cyclooxygenase-2 in human gastric carcinoma
-
Ristimaki A, Honkanen N, Jankala H, et al. Expression of cyclooxygenase-2 in human gastric carcinoma. Cancer Res 1997;57:1276-1280.
-
(1997)
Cancer Res
, vol.57
, pp. 1276-1280
-
-
Ristimaki, A.1
Honkanen, N.2
Jankala, H.3
-
82
-
-
0029783253
-
Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells
-
Subbaramaiah K, Telang N, Ramonetti JT, et al. Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells. Cancer Res 1996;56:4424-4429.
-
(1996)
Cancer Res
, vol.56
, pp. 4424-4429
-
-
Subbaramaiah, K.1
Telang, N.2
Ramonetti, J.T.3
-
83
-
-
0033105360
-
Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck
-
Chan G, Boyle JO, Yang EK, et al. Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck. Cancer Res 1999;59:991-994.
-
(1999)
Cancer Res
, vol.59
, pp. 991-994
-
-
Chan, G.1
Boyle, J.O.2
Yang, E.K.3
-
84
-
-
0033106051
-
Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer
-
Tucker ON, Dannenberg AJ, Yang EK, et al. Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res 1999;59:987-990.
-
(1999)
Cancer Res
, vol.59
, pp. 987-990
-
-
Tucker, O.N.1
Dannenberg, A.J.2
Yang, E.K.3
-
86
-
-
0036114348
-
A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis
-
Phillips RK, Wallace MH, Lynch PM, et al. A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis. Gut 2002;50:857-860.
-
(2002)
Gut
, vol.50
, pp. 857-860
-
-
Phillips, R.K.1
Wallace, M.H.2
Lynch, P.M.3
-
87
-
-
0142250380
-
A randomized, double-blind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients
-
Higuchi T, Iwama T, Yoshinaga K, et al. A randomized, double-blind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients. Clin Cancer Res 2003;9:4756-4760.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4756-4760
-
-
Higuchi, T.1
Iwama, T.2
Yoshinaga, K.3
-
88
-
-
0032006784
-
Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis
-
Kawamori T, Rao CV, Seibert K, Reddy BS. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res 1998;58:409-412.
-
(1998)
Cancer Res
, vol.58
, pp. 409-412
-
-
Kawamori, T.1
Rao, C.V.2
Seibert, K.3
Reddy, B.S.4
-
89
-
-
20444501268
-
Evaluation of cyclooxygenase-1 and cyclooxygenase-2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma
-
Sorenmo K, Goldschmidt M, Shofer F, et al. Evaluation of cyclooxygenase-1 and cyclooxygenase-2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma. Vet Comp Oncol 2004;2:13-23.
-
(2004)
Vet Comp Oncol
, vol.2
, pp. 13-23
-
-
Sorenmo, K.1
Goldschmidt, M.2
Shofer, F.3
-
90
-
-
0037430063
-
Aspirin use and cancers of the upper aerodigestive tract
-
Bosetti C, Talamini R, Franceschi S, et al. Aspirin use and cancers of the upper aerodigestive tract. Br J Cancer 2003;88:672-674.
-
(2003)
Br J Cancer
, vol.88
, pp. 672-674
-
-
Bosetti, C.1
Talamini, R.2
Franceschi, S.3
-
91
-
-
0021870243
-
Experimentally induced phenylbutazone toxicosis in ponies: Description of the syndrome and its prevention with synthetic prostaglandin E2
-
Collins LG, Tyler DE. Experimentally induced phenylbutazone toxicosis in ponies: Description of the syndrome and its prevention with synthetic prostaglandin E2. Am J Vet Res 1985;46:1605-1615.
-
(1985)
Am J Vet Res
, vol.46
, pp. 1605-1615
-
-
Collins, L.G.1
Tyler, D.E.2
-
92
-
-
0032946862
-
Prostaglandin-induced recovery of barrier function in porcine ileum is triggered by chloride secretion
-
Blikslager AT, Roberts MC, Argenzio RA. Prostaglandin-induced recovery of barrier function in porcine ileum is triggered by chloride secretion. Am J Physiol 1999;276:G28-G36.
-
(1999)
Am J Physiol
, vol.276
-
-
Blikslager, A.T.1
Roberts, M.C.2
Argenzio, R.A.3
-
93
-
-
0027275448
-
Gastroduodenal ulceration associated with flunixin meglumine administration in three dogs
-
Vonderhaar MA, Salisbury SK. Gastroduodenal ulceration associated with flunixin meglumine administration in three dogs. J Am Vet Med Assoc 1993;203:92-95.
-
(1993)
J Am Vet Med Assoc
, vol.203
, pp. 92-95
-
-
Vonderhaar, M.A.1
Salisbury, S.K.2
-
94
-
-
0041885420
-
Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs
-
MacDonald TM, Morant SV, Goldstein JL, et al. Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs. Gut 2003;52:1265-1270.
-
(2003)
Gut
, vol.52
, pp. 1265-1270
-
-
MacDonald, T.M.1
Morant, S.V.2
Goldstein, J.L.3
-
95
-
-
0037003171
-
Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler
-
Reed S. Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler. Can Vet J 2002;43:971-972.
-
(2002)
Can Vet J
, vol.43
, pp. 971-972
-
-
Reed, S.1
-
96
-
-
0019975343
-
Relationship of gastric mucosal damage induced in pigs by antiinflammatory drugs to their effects on prostaglandin production
-
Rainsford KD, Willis C. Relationship of gastric mucosal damage induced in pigs by antiinflammatory drugs to their effects on prostaglandin production. Dig Dis Sci 1982;27:624-635.
-
(1982)
Dig Dis Sci
, vol.27
, pp. 624-635
-
-
Rainsford, K.D.1
Willis, C.2
-
97
-
-
0031752836
-
Cyclooxygenase selectivity and the risk of gastrointestinal complications of various non-steroidal anti-inflammatory drugs: A clinical consideration
-
Kawai S. Cyclooxygenase selectivity and the risk of gastrointestinal complications of various non-steroidal anti-inflammatory drugs: A clinical consideration. Inflamm Res 1998;47(Suppl 2):S102-S106.
-
(1998)
Inflamm Res
, vol.47
, Issue.2 SUPPL.
-
-
Kawai, S.1
-
98
-
-
0030013358
-
NSAIDs, gastrointestinal injury, and cytoprotection
-
Scheiman JM. NSAIDs, gastrointestinal injury, and cytoprotection. Gastroenterol Clin North Am 1996;25:279-298.
-
(1996)
Gastroenterol Clin North Am
, vol.25
, pp. 279-298
-
-
Scheiman, J.M.1
-
99
-
-
0028843881
-
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
-
Langenbach R, Morham SG, Tiano HF, et al. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 1995;83:483-492.
-
(1995)
Cell
, vol.83
, pp. 483-492
-
-
Langenbach, R.1
Morham, S.G.2
Tiano, H.F.3
-
100
-
-
0033851568
-
NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2
-
Wallace JL, McKnight W, Reuter BK, Vergnolle N. NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2. Gastroenterology 2000;119:706-714.
-
(2000)
Gastroenterology
, vol.119
, pp. 706-714
-
-
Wallace, J.L.1
McKnight, W.2
Reuter, B.K.3
Vergnolle, N.4
-
101
-
-
0035067053
-
Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge
-
Gretzer B, Maricic N, Respondek M, et al. Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge. Br J Pharmacol 2001;132:1565-1573.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1565-1573
-
-
Gretzer, B.1
Maricic, N.2
Respondek, M.3
-
102
-
-
14844353986
-
Superiority of the gastroduodenal safety profile of licofelone over rofecoxib, a COX-2 selective inhibitor, in dogs
-
Moreau M, Daminet S, Martel-Pelletier J, et al. Superiority of the gastroduodenal safety profile of licofelone over rofecoxib, a COX-2 selective inhibitor, in dogs. J Vet Pharmacol Ther 2005;28:81-86.
-
(2005)
J Vet Pharmacol Ther
, vol.28
, pp. 81-86
-
-
Moreau, M.1
Daminet, S.2
Martel-Pelletier, J.3
-
103
-
-
0036546680
-
Inhibition of proliferation of gastric epithelial cells by a cyclooxygenase 2 inhibitor, JTE522, is also mediated by a PGE2-independent pathway
-
Hirose M, Miwa H, Kobayashi O, et al. Inhibition of proliferation of gastric epithelial cells by a cyclooxygenase 2 inhibitor, JTE522, is also mediated by a PGE2-independent pathway. Aliment Pharmacol Ther 2002;16(Suppl 2):83-89.
-
(2002)
Aliment Pharmacol Ther
, vol.16
, Issue.2 SUPPL.
, pp. 83-89
-
-
Hirose, M.1
Miwa, H.2
Kobayashi, O.3
-
104
-
-
0032750920
-
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
-
Jones MK, Wang H, Peskar BM, et al. Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing. Nat Med 1999;5:1418-1423.
-
(1999)
Nat Med
, vol.5
, pp. 1418-1423
-
-
Jones, M.K.1
Wang, H.2
Peskar, B.M.3
-
105
-
-
0031884213
-
Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastrointestinal ulcer models in rats
-
Schmassmann A, Peskar BM, Stettler C, et al. Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastrointestinal ulcer models in rats. Br J Pharmacol 1998;123:795-804.
-
(1998)
Br J Pharmacol
, vol.123
, pp. 795-804
-
-
Schmassmann, A.1
Peskar, B.M.2
Stettler, C.3
-
107
-
-
0031679914
-
Interspecies differences in renal localization of cyclooxygenase isoforms: Implications in nonsteroidal antiinflammatory drug-related nephrotoxicity
-
Khan KN, Venturini CM, Bunch RT, et al. Interspecies differences in renal localization of cyclooxygenase isoforms: Implications in nonsteroidal antiinflammatory drug-related nephrotoxicity. Toxicol Pathol 1998;26:612-620.
-
(1998)
Toxicol Pathol
, vol.26
, pp. 612-620
-
-
Khan, K.N.1
Venturini, C.M.2
Bunch, R.T.3
-
108
-
-
0028034970
-
Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
-
Harris RC, McKanna JA, Akai Y, et al. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest 1994;94:2504-2510.
-
(1994)
J Clin Invest
, vol.94
, pp. 2504-2510
-
-
Harris, R.C.1
McKanna, J.A.2
Akai, Y.3
-
109
-
-
0032867546
-
Immunolocalization of cyclooxygenase-2 in the macula densa of human elderly
-
Nantel F, Meadows E, Denis D, et al. Immunolocalization of cyclooxygenase-2 in the macula densa of human elderly. FEBS Lett 1999;457:475-477.
-
(1999)
FEBS Lett
, vol.457
, pp. 475-477
-
-
Nantel, F.1
Meadows, E.2
Denis, D.3
-
110
-
-
0032929359
-
Angiotensin II attenuates renal cortical cyclooxygenase-2 expression
-
Cheng HF, Wang JL, Zhang MZ, et al. Angiotensin II attenuates renal cortical cyclooxygenase-2 expression. J Clin Invest 1999;103:953-961.
-
(1999)
J Clin Invest
, vol.103
, pp. 953-961
-
-
Cheng, H.F.1
Wang, J.L.2
Zhang, M.Z.3
-
111
-
-
0032793945
-
Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension
-
Wang JL, Cheng HF, Harris RC. Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension. Hypertension 1999;34:96-101.
-
(1999)
Hypertension
, vol.34
, pp. 96-101
-
-
Wang, J.L.1
Cheng, H.F.2
Harris, R.C.3
-
112
-
-
0033866758
-
Chronic cyclooxygenase-2 inhibition blunts low sodium-stimulated renin without changing renal haemodynamics
-
Harding P, Carretero OA, Beierwaltes WH. Chronic cyclooxygenase-2 inhibition blunts low sodium-stimulated renin without changing renal haemodynamics. J Hypertens 2000;18:1107-1113.
-
(2000)
J Hypertens
, vol.18
, pp. 1107-1113
-
-
Harding, P.1
Carretero, O.A.2
Beierwaltes, W.H.3
-
113
-
-
0032739363
-
Inhibition of macula densa-stimulated renin secretion by pharmacological blockade of cyclooxygenase-2
-
Traynor TR, Smart A, Briggs JP, Schnermann J. Inhibition of macula densa-stimulated renin secretion by pharmacological blockade of cyclooxygenase-2. Am J Physiol 1999;277:F706-F710.
-
(1999)
Am J Physiol
, vol.277
-
-
Traynor, T.R.1
Smart, A.2
Briggs, J.P.3
Schnermann, J.4
-
114
-
-
0031946336
-
Regulation of cyclooxygenase expression in the kidney by dietary salt intake
-
Yang T, Singh I, Pham H, et al. Regulation of cyclooxygenase expression in the kidney by dietary salt intake. Am J Physiol 1998;274:F481-F489.
-
(1998)
Am J Physiol
, vol.274
-
-
Yang, T.1
Singh, I.2
Pham, H.3
-
115
-
-
0033894982
-
Renal changes induced by a cyclooxygenase-2 inhibitor during normal and low sodium intake
-
Rodriguez F, Llinas MT, Gonzalez JD, et al. Renal changes induced by a cyclooxygenase-2 inhibitor during normal and low sodium intake. Hypertension 2000;36:276-281.
-
(2000)
Hypertension
, vol.36
, pp. 276-281
-
-
Rodriguez, F.1
Llinas, M.T.2
Gonzalez, J.D.3
-
116
-
-
0036764153
-
COX-2-specific inhibitors and the kidney: Effect on hypertension and oedema
-
Whelton A. COX-2-specific inhibitors and the kidney: Effect on hypertension and oedema. J Hypertens 2002;20(Suppl 6):S31-S35.
-
(2002)
J Hypertens
, vol.20
, Issue.6 SUPPL.
-
-
Whelton, A.1
-
117
-
-
0025934766
-
Nonsteroidal anti-inflammatory drugs: Effects on kidney function
-
Whelton A, Hamilton CW. Nonsteroidal anti-inflammatory drugs: Effects on kidney function. J Clin Pharmacol 1991;31:588-598.
-
(1991)
J Clin Pharmacol
, vol.31
, pp. 588-598
-
-
Whelton, A.1
Hamilton, C.W.2
-
118
-
-
0035999429
-
Cyclo-oxygenase 2 function is essential for bone fracture healing
-
Simon AM, Manigrasso MB, O'Connor JP. Cyclo-oxygenase 2 function is essential for bone fracture healing. J Bone Miner Res 2002;17:963-976.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 963-976
-
-
Simon, A.M.1
Manigrasso, M.B.2
O'Connor, J.P.3
-
119
-
-
0012429950
-
Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs
-
Gerstenfeld LC, Thiede M, Seibert K, et al. Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs. J Orthop Res 2003;21:670-675.
-
(2003)
J Orthop Res
, vol.21
, pp. 670-675
-
-
Gerstenfeld, L.C.1
Thiede, M.2
Seibert, K.3
-
120
-
-
0019514330
-
Release of prostaglandins from bone and muscle after tibial fracture. An experimental study in rabbits
-
Dekel S, Lenthall G, Francis MJ. Release of prostaglandins from bone and muscle after tibial fracture. An experimental study in rabbits. J Bone Joint Surg Br 1981;63-B:185-189.
-
(1981)
J Bone Joint Surg Br
, vol.63 B
, pp. 185-189
-
-
Dekel, S.1
Lenthall, G.2
Francis, M.J.3
-
122
-
-
0036259278
-
Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
-
Zhang X, Schwarz EM, Young DA, et al. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J Clin Invest 2002;109:1405-1415.
-
(2002)
J Clin Invest
, vol.109
, pp. 1405-1415
-
-
Zhang, X.1
Schwarz, E.M.2
Young, D.A.3
-
124
-
-
0035076411
-
Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis
-
Zhang X, Morham SG, Langenbach R, et al. Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis. J Bone Miner Res 2001;16:660-670.
-
(2001)
J Bone Miner Res
, vol.16
, pp. 660-670
-
-
Zhang, X.1
Morham, S.G.2
Langenbach, R.3
-
125
-
-
0031836045
-
Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells
-
Min YK, Rao Y, Okada Y, et al. Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells. J Bone Miner Res 1998;13:1066-1075.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 1066-1075
-
-
Min, Y.K.1
Rao, Y.2
Okada, Y.3
-
126
-
-
0031392391
-
Involvement of prostaglandin endoperoxide H synthase-2 in osteoclast formation induced by parathyroid hormone
-
Tokushima T, Sato T, Morita I, Murota S. Involvement of prostaglandin endoperoxide H synthase-2 in osteoclast formation induced by parathyroid hormone. Adv Exp Med Biol 1997;433:307-309.
-
(1997)
Adv Exp Med Biol
, vol.433
, pp. 307-309
-
-
Tokushima, T.1
Sato, T.2
Morita, I.3
Murota, S.4
-
127
-
-
8244250135
-
Transcriptional induction of cyclooxygenase-2 in osteoblasts is involved in interleukin-6-induced osteoclast formation
-
Tai H, Miyaura C, Pilbeam CC, et al. Transcriptional induction of cyclooxygenase-2 in osteoblasts is involved in interleukin-6-induced osteoclast formation. Endocrinology 1997;138:2372-2379.
-
(1997)
Endocrinology
, vol.138
, pp. 2372-2379
-
-
Tai, H.1
Miyaura, C.2
Pilbeam, C.C.3
-
128
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
Kotake S, Udagawa N, Takahashi N, et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 1999;103:1345-1352.
-
(1999)
J Clin Invest
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
-
129
-
-
0035673517
-
Cyclo-oxygenase isoenzymes. Structural basis for selective inhibition of cyclo-oxygenases by anti-inflammatory agents
-
Fiorucci S, Antonelli E. Cyclo-oxygenase isoenzymes. Structural basis for selective inhibition of cyclo-oxygenases by anti-inflammatory agents. Dig Liver Dis 2001;33(Suppl 2):S2-S7.
-
(2001)
Dig Liver Dis
, vol.33
, Issue.2 SUPPL.
-
-
Fiorucci, S.1
Antonelli, E.2
-
130
-
-
0035421783
-
Profile and prevalence of aspirin resistance in patients with cardiovascular disease
-
Gum PA, Kottke-Marchant K, Poggio ED, et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease. Am J Cardiol 2001;88:230-235.
-
(2001)
Am J Cardiol
, vol.88
, pp. 230-235
-
-
Gum, P.A.1
Kottke-Marchant, K.2
Poggio, E.D.3
-
131
-
-
0033943280
-
Salicylate metabolites inhibit cyclooxygenase-2-dependent prostaglandin E(2) synthesis in murine macrophages
-
Hinz B, Kraus V, Pahl A, Brune K. Salicylate metabolites inhibit cyclooxygenase-2-dependent prostaglandin E(2) synthesis in murine macrophages. Biochem Biophys Res Commun 2000;274:197-202.
-
(2000)
Biochem Biophys Res Commun
, vol.274
, pp. 197-202
-
-
Hinz, B.1
Kraus, V.2
Pahl, A.3
Brune, K.4
-
132
-
-
0001299961
-
Acetylation of prostaglandin synthase by aspirin
-
USA
-
Roth GJ, Stanford N, Majerus PW. Acetylation of prostaglandin synthase by aspirin. Proc Natl Acad Sci USA 1975;72:3073-3076.
-
(1975)
Proc Natl Acad Sci
, vol.72
, pp. 3073-3076
-
-
Roth, G.J.1
Stanford, N.2
Majerus, P.W.3
-
133
-
-
0035924765
-
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin
-
Catella-Lawson F, Reilly MP, Kapoor SC, et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. N Engl J Med 2001;345:1809-1817.
-
(2001)
N Engl J Med
, vol.345
, pp. 1809-1817
-
-
Catella-Lawson, F.1
Reilly, M.P.2
Kapoor, S.C.3
-
134
-
-
0035853050
-
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice
-
USA
-
Pratico D, Tillmann C, Zhang ZB, et al. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. Proc Natl Acad Sci USA 2001;98:3358-3363.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 3358-3363
-
-
Pratico, D.1
Tillmann, C.2
Zhang, Z.B.3
-
135
-
-
1242340306
-
Nonsteroidal anti-inflammatory drugs and cardiovascular risk
-
Howard PA, Delafontaine P. Nonsteroidal anti-inflammatory drugs and cardiovascular risk. J Am Coll Cardiol 2004;43:519-525.
-
(2004)
J Am Coll Cardiol
, vol.43
, pp. 519-525
-
-
Howard, P.A.1
Delafontaine, P.2
-
136
-
-
0035846658
-
Cyclooxygenase-2 blockade does not impair endothelial vasodilator function in healthy volunteers: Randomized evaluation of rofecoxib versus naproxen on endothelium-dependent vasodilatation
-
Verma S, Raj SR, Shewchuk L, et al. Cyclooxygenase-2 blockade does not impair endothelial vasodilator function in healthy volunteers: Randomized evaluation of rofecoxib versus naproxen on endothelium-dependent vasodilatation. Circulation 2001;104:2879-2882.
-
(2001)
Circulation
, vol.104
, pp. 2879-2882
-
-
Verma, S.1
Raj, S.R.2
Shewchuk, L.3
-
137
-
-
0034644396
-
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
-
Silverstein FE, Faich G, Goldstein JL, et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. JAMA 2000;284:1247-1255.
-
(2000)
JAMA
, vol.284
, pp. 1247-1255
-
-
Silverstein, F.E.1
Faich, G.2
Goldstein, J.L.3
-
138
-
-
4344661128
-
Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: Randomised controlled trial
-
Schnitzer TJ, Burmester GR, Mysler E, et al. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: Randomised controlled trial. Lancet 2004;364:665-674.
-
(2004)
Lancet
, vol.364
, pp. 665-674
-
-
Schnitzer, T.J.1
Burmester, G.R.2
Mysler, E.3
-
139
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
Dinchuk JE, Car BD, Focht RJ, et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 1995;378:406-409.
-
(1995)
Nature
, vol.378
, pp. 406-409
-
-
Dinchuk, J.E.1
Car, B.D.2
Focht, R.J.3
-
140
-
-
0030702122
-
Multiple female reproductive failures in cyclooxygenase 2-deficient mice
-
Lim H, Paria BC, Das SK, et al. Multiple female reproductive failures in cyclooxygenase 2-deficient mice. Cell 1997;91:197-208.
-
(1997)
Cell
, vol.91
, pp. 197-208
-
-
Lim, H.1
Paria, B.C.2
Das, S.K.3
-
141
-
-
0029949756
-
Developmental expression of the cyclo-oxygenase-1 and cyclo-oxygenase-2 genes in the peri-implantation mouse uterus and their differential regulation by the blastocyst and ovarian steroids
-
Chakraborty I, Das SK, Wang J, Dey SK. Developmental expression of the cyclo-oxygenase-1 and cyclo-oxygenase-2 genes in the peri-implantation mouse uterus and their differential regulation by the blastocyst and ovarian steroids. J Mol Endocrinol 1996;16:107-122.
-
(1996)
J Mol Endocrinol
, vol.16
, pp. 107-122
-
-
Chakraborty, I.1
Das, S.K.2
Wang, J.3
Dey, S.K.4
-
142
-
-
0029740064
-
Localization of prostaglandin H synthase type 2 protein and mRNA in term human fetal membranes and decidua
-
Gibb W, Sun M. Localization of prostaglandin H synthase type 2 protein and mRNA in term human fetal membranes and decidua. J Endocrinol 1996;150:497-503.
-
(1996)
J Endocrinol
, vol.150
, pp. 497-503
-
-
Gibb, W.1
Sun, M.2
-
143
-
-
0035970022
-
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
-
USA
-
Loftin CD, Trivedi DB, Tiano HF, et al. Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2. Proc Natl Acad Sci USA 2001;98:1059-1064.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 1059-1064
-
-
Loftin, C.D.1
Trivedi, D.B.2
Tiano, H.F.3
-
144
-
-
0033256614
-
Role of the nitric oxide-cGMP system in the regulation of ductus arteriosus patency in fetal rats
-
Takizawa T, Horikoshi E, Kamata A. Role of the nitric oxide-cGMP system in the regulation of ductus arteriosus patency in fetal rats. J Vet Med Sci 1999;61:1277-1280.
-
(1999)
J Vet Med Sci
, vol.61
, pp. 1277-1280
-
-
Takizawa, T.1
Horikoshi, E.2
Kamata, A.3
-
145
-
-
0033945934
-
Cyclooxygenase-2-selective inhibitors impair glomerulogenesis and renal cortical development
-
Komhoff M, Wang JL, Cheng HF, et al. Cyclooxygenase-2-selective inhibitors impair glomerulogenesis and renal cortical development. Kidney Int 2000;57:414-422.
-
(2000)
Kidney Int
, vol.57
, pp. 414-422
-
-
Komhoff, M.1
Wang, J.L.2
Cheng, H.F.3
-
146
-
-
0028902109
-
Characterization of inducible cyclooxygenase in rat brain
-
Breder CD, Dewitt D, Kraig RP. Characterization of inducible cyclooxygenase in rat brain. J Comp Neurol 1995;355:296-315.
-
(1995)
J Comp Neurol
, vol.355
, pp. 296-315
-
-
Breder, C.D.1
Dewitt, D.2
Kraig, R.P.3
-
147
-
-
0029995029
-
COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex
-
USA
-
Kaufmann WE, Worley PF, Pegg J, et al. COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc Natl Acad Sci USA 1996;93:2317-2321.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 2317-2321
-
-
Kaufmann, W.E.1
Worley, P.F.2
Pegg, J.3
-
149
-
-
0031689543
-
Cyclooxygenase in biology and disease
-
DuBois RN, Abramson SB, Crofford L, et al. Cyclooxygenase in biology and disease. FASEB J 1998;12:1063-1073.
-
(1998)
FASEB J
, vol.12
, pp. 1063-1073
-
-
DuBois, R.N.1
Abramson, S.B.2
Crofford, L.3
-
150
-
-
0030590429
-
Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: A possible site of prostaglandin synthesis responsible for fever
-
Cao C, Matsumura K, Yamagata K, Watanabe Y. Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: A possible site of prostaglandin synthesis responsible for fever. Brain Res 1996;733:263-272.
-
(1996)
Brain Res
, vol.733
, pp. 263-272
-
-
Cao, C.1
Matsumura, K.2
Yamagata, K.3
Watanabe, Y.4
-
151
-
-
0035932121
-
Interleukin-1-beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity
-
Samad TA, Moore KA, Sapirstein A, et al. Interleukin-1-beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 2001;410:471-475.
-
(2001)
Nature
, vol.410
, pp. 471-475
-
-
Samad, T.A.1
Moore, K.A.2
Sapirstein, A.3
-
152
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
-
McGeer PL, Schulzer M, McGeer EG. Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies. Neurology 1996;47:425-432.
-
(1996)
Neurology
, vol.47
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
153
-
-
0032450999
-
NSAIDs and incident Alzheimer's disease. The Rotterdam Study
-
in 't Veld BA, Launer LJ, Hoes AW, et al. NSAIDs and incident Alzheimer's disease. The Rotterdam Study. Neurobiol Aging 1998;19:607-611.
-
(1998)
Neurobiol Aging
, vol.19
, pp. 607-611
-
-
In 't Veld, B.A.1
Launer, L.J.2
Hoes, A.W.3
-
154
-
-
0036242939
-
Evaluation of selective COX-2 inhibitors for the treatment of Alzheimer's disease
-
Aisen PS. Evaluation of selective COX-2 inhibitors for the treatment of Alzheimer's disease. J Pain Symptom Manage 2002;23:S35-S40.
-
(2002)
J Pain Symptom Manage
, vol.23
-
-
Aisen, P.S.1
-
155
-
-
0034924557
-
Cyclooxygenase and Alzheimer's disease: Implications for preventive initiatives to slow the progression of clinical dementia
-
Pasinetti GM. Cyclooxygenase and Alzheimer's disease: Implications for preventive initiatives to slow the progression of clinical dementia. Arch Gerontol Geriatr 2001;33:13-28.
-
(2001)
Arch Gerontol Geriatr
, vol.33
, pp. 13-28
-
-
Pasinetti, G.M.1
-
156
-
-
0033452430
-
Profile and mechanisms of gastrointestinal and other side effects of nonsteroidal anti-inflammatory drugs (NSAIDs)
-
Rainsford KD. Profile and mechanisms of gastrointestinal and other side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). Am J Med 1999;107:27S-35S.
-
(1999)
Am J Med
, vol.107
-
-
Rainsford, K.D.1
-
157
-
-
0027268393
-
Clinical trial of indomethacin in Alzheimer's disease
-
Rogers J, Kirby LC, Hempelman SR, et al. Clinical trial of indomethacin in Alzheimer's disease. Neurology 1993;43:1609-1611.
-
(1993)
Neurology
, vol.43
, pp. 1609-1611
-
-
Rogers, J.1
Kirby, L.C.2
Hempelman, S.R.3
-
158
-
-
0033815066
-
The absorption, distribution, metabolism and excretion of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in rats and dogs
-
Halpin RA, Geer LA, Zhang KE, et al. The absorption, distribution, metabolism and excretion of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in rats and dogs. Drug Metab Dispos 2000;28:1244-1254.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1244-1254
-
-
Halpin, R.A.1
Geer, L.A.2
Zhang, K.E.3
-
159
-
-
0036040079
-
N-oxidation of drugs associated with idiosyncratic drug reactions
-
Uetrecht J. N-oxidation of drugs associated with idiosyncratic drug reactions. Drug Metab Rev 2002;34:651-665.
-
(2002)
Drug Metab Rev
, vol.34
, pp. 651-665
-
-
Uetrecht, J.1
-
160
-
-
0142025460
-
Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics
-
Strom BL, Schinnar R, Apter AJ, et al. Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics. N Engl J Med 2003;349:1628-1635.
-
(2003)
N Engl J Med
, vol.349
, pp. 1628-1635
-
-
Strom, B.L.1
Schinnar, R.2
Apter, A.J.3
-
161
-
-
3042800902
-
Idiosyncratic toxicity associated with potentiated sulfonamides in the dog
-
Trepanier LA. Idiosyncratic toxicity associated with potentiated sulfonamides in the dog. J Vet Pharmacol Ther 2004;27:129-138.
-
(2004)
J Vet Pharmacol Ther
, vol.27
, pp. 129-138
-
-
Trepanier, L.A.1
-
162
-
-
0037108979
-
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
-
USA
-
Chandrasekharan NV, Dai H, Roos KL, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proc Natl Acad Sci USA 2002;99:13926-13931.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 13926-13931
-
-
Chandrasekharan, N.V.1
Dai, H.2
Roos, K.L.3
-
163
-
-
0036831596
-
Cyclooxygenase 1 (COX1) polymorphisms in African-American and Caucasian populations
-
Ulrich CM, Bigler J, Sibert J, et al. Cyclooxygenase 1 (COX1) polymorphisms in African-American and Caucasian populations. Hum Mutat 2002;20:409-410.
-
(2002)
Hum Mutat
, vol.20
, pp. 409-410
-
-
Ulrich, C.M.1
Bigler, J.2
Sibert, J.3
-
164
-
-
0242357690
-
The molecular biology and regulation of 5-lipoxygenase
-
Radmark OP. The molecular biology and regulation of 5-lipoxygenase. Am J Respir Crit Care Med 2000;161:S11-S15.
-
(2000)
Am J Respir Crit Care Med
, vol.161
-
-
Radmark, O.P.1
-
165
-
-
0032192089
-
Role of leukotrienes in antimicrobial defense of the lung
-
Peters-Golden M, Coffey M. Role of leukotrienes in antimicrobial defense of the lung. J Lab Clin Med 1998;132:251-257.
-
(1998)
J Lab Clin Med
, vol.132
, pp. 251-257
-
-
Peters-Golden, M.1
Coffey, M.2
-
166
-
-
0037527546
-
COX-LOX inhibition: Current evidence for an emerging new therapy
-
Skelly MM, Hawkey CJ. COX-LOX inhibition: Current evidence for an emerging new therapy. Int J Clin Pract 2003;57:301-304.
-
(2003)
Int J Clin Pract
, vol.57
, pp. 301-304
-
-
Skelly, M.M.1
Hawkey, C.J.2
-
167
-
-
0035584272
-
Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?
-
Fiorucci S, Meli R, Bucci M, Cirino G. Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy? Biochem Pharmacol 2001;62:1433-1438.
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 1433-1438
-
-
Fiorucci, S.1
Meli, R.2
Bucci, M.3
Cirino, G.4
-
168
-
-
0034757635
-
Pros and cons of selective inhibition of cyclooxygenase-2 versus dual lipoxygenase/cyclooxygenase inhibition: Is two better than one?
-
Parente L. Pros and cons of selective inhibition of cyclooxygenase-2 versus dual lipoxygenase/cyclooxygenase inhibition: Is two better than one? J Rheumatol 2001;28:2375-2382.
-
(2001)
J Rheumatol
, vol.28
, pp. 2375-2382
-
-
Parente, L.1
-
169
-
-
0026569273
-
Cloning and characterization of inducible nitric oxide synthase from mouse macrophages
-
Xie QW, Cho HJ, Calaycay J, et al. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 1992;256:225-228.
-
(1992)
Science
, vol.256
, pp. 225-228
-
-
Xie, Q.W.1
Cho, H.J.2
Calaycay, J.3
-
170
-
-
0030871687
-
COX-1 and COX-2 tissue expression: Implications and predictions
-
Crofford LJ. COX-1 and COX-2 tissue expression: Implications and predictions. J Rheumatol Suppl 1997;49:15-19.
-
(1997)
J Rheumatol Suppl
, vol.49
, pp. 15-19
-
-
Crofford, L.J.1
-
171
-
-
0026495220
-
Nitric oxide donors increase mucus gel thickness in rat stomach
-
Brown JF, Hanson PJ, Whittle BJ. Nitric oxide donors increase mucus gel thickness in rat stomach. Eur J Pharmacol 1992;223:103-104.
-
(1992)
Eur J Pharmacol
, vol.223
, pp. 103-104
-
-
Brown, J.F.1
Hanson, P.J.2
Whittle, B.J.3
-
172
-
-
0036080302
-
Gastroprotective effects of amtolmetin guacyl: A new non-steroidal anti-inflammatory drug that activates inducible gastric nitric oxide synthase
-
Coruzzi G, Coppelli G, Spaggiari S, et al. Gastroprotective effects of amtolmetin guacyl: A new non-steroidal anti-inflammatory drug that activates inducible gastric nitric oxide synthase. Dig Liver Dis 2002;34:403-410.
-
(2002)
Dig Liver Dis
, vol.34
, pp. 403-410
-
-
Coruzzi, G.1
Coppelli, G.2
Spaggiari, S.3
-
173
-
-
0033594911
-
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
-
USA
-
Warner TD, Giuliano F, Vojnovic I, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis. Proc Natl Acad Sci USA 1999;96:7563-7568.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 7563-7568
-
-
Warner, T.D.1
Giuliano, F.2
Vojnovic, I.3
-
174
-
-
0031740348
-
Evaluation of selective inhibition of canine cyclooxygenase 1 and 2 by carprofen and other nonsteroidal anti-inflammatory drugs
-
Ricketts AP, Lundy KM, Seibel SB. Evaluation of selective inhibition of canine cyclooxygenase 1 and 2 by carprofen and other nonsteroidal anti-inflammatory drugs. Am J Vet Res 1998;59:1441-1446.
-
(1998)
Am J Vet Res
, vol.59
, pp. 1441-1446
-
-
Ricketts, A.P.1
Lundy, K.M.2
Seibel, S.B.3
-
175
-
-
13444266910
-
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib)
-
Penning TD, Talley JJ, Bertenshaw SR, et al. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benze nesulfonamide (SC-58635, celecoxib). J Med Chem 1997;40:1347-1365.
-
(1997)
J Med Chem
, vol.40
, pp. 1347-1365
-
-
Penning, T.D.1
Talley, J.J.2
Bertenshaw, S.R.3
-
176
-
-
0033524421
-
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
-
USA
-
McAdam BF, Catella-Lawson F, Mardini IA, et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci USA 1999;96:272-277.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 272-277
-
-
McAdam, B.F.1
Catella-Lawson, F.2
Mardini, I.A.3
-
177
-
-
0032702213
-
Cyclooxygenase 2 inhibitors: Discovery, selectivity and the future
-
Marnett LJ, Kalgutkar AS. Cyclooxygenase 2 inhibitors: Discovery, selectivity and the future. Trends Pharmacol Sci 1999;20:465-469.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 465-469
-
-
Marnett, L.J.1
Kalgutkar, A.S.2
-
178
-
-
0034816925
-
Cyclooxygenase-independent actions of cyclooxygenase inhibitors
-
Tegeder I, Pfeilschifter J, Geisslinger G. Cyclooxygenase-independent actions of cyclooxygenase inhibitors. FASEB J 2001;15:2057-2072.
-
(2001)
FASEB J
, vol.15
, pp. 2057-2072
-
-
Tegeder, I.1
Pfeilschifter, J.2
Geisslinger, G.3
|