Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells

Cancer Research

Volumn 56, Issue 19, 1996, Pages 4424-4429

  Subbaramaiah, Kotha ^a,b   Telang, Nitin ^b   Ramonetti, John T ^a,b   Araki, Ruriko ^b   DeVito, Bethany ^a   Weksler, Babette B ^a   Dannenberg, Andrew J ^a,b,c  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b STRANG CANCER PREVENTION CENTER   (United States)

^c WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; ONCOPROTEIN; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CELL TRANSFORMATION; ENZYME REGULATION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; STRAIN DIFFERENCE; VIRUS TRANSFORMATION;

ANIMALS; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; CELL TRANSFORMATION, VIRAL; CYCLOOXYGENASE 1; DINOPROSTONE; EPITHELIAL CELLS; EPITHELIUM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; ISOENZYMES; MAMMARY GLANDS, ANIMAL; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NEOPLASM PROTEINS; ONCOGENES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; RNA, NEOPLASM; TRANSCRIPTION, GENETIC;

EID: 0029783253     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Bennett, A., Charlier, E. M., McDonald, A. M., Simpson, J. S., Stamford, I. F , and Zebro, T Prostaglandins and breast cancer Lancet, 2: 624-626, 1977
2. Bennett, A The production of prostanoids in human cancers, and their implications for tumor progression Prog. Lipid Res., 25: 539-542, 1986
3. Jung, T. T K , Berlinger, N. T , and Juhn, S. K Prostaglandins in squamous cell carcinoma of the head and neck a preliminary study. Laryngoscope, 95 307-312, 1985.
4. Bennett, A , Carroll, M A., Stamford, I. F , Whimster, W. F., and Williams, F. Prostaglandins and human lung carcinomas. Br. J. Cancer, 46, 888-893, 1982.
5. Bennett, A , Civier, A., Hensby, C. N , Melhuish, P B , and Stamford, I. F. Measurement of arachidonate and its metabolites extracted from human normal and malignant gasirointestinal tissues. Gut, 28: 315-318, 1987.
6. Rigas, B., Goldman, I S., and Levine, L. Altered eicosanoid levels in human colon cancer J. Lab. Clin. Med. 122: 518-523, 1993
7. Marnett, L. J Aspirin and the potential role of prostaglandins in colon cancer Cancer Res., 52: 5575-5589, 1992
8. Giardiello, F. M , Hamilton, S. R., Krush, A. J., Piantodosi, S., Hylind, L. M , Cleano, P., Booker, S. V , Robinson, R. C., and Offerhaus, G. J. A. Treatment of colonic rectal adenomas with sulindac in familial adenomatous polyposis. N. Engl. J. Med., 328: 1313-1316, 1993.
9. Rao, C. V., Rivenson, A., Simi, B., Zang, E., Kelloff, G., Steele, V., and Reddy, B S. Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent Cancer Res , 55: 1464-1472, 1995.
10. Huang, M-T., Wang, Z Y , Georgiadis, C. A., Laskin, J. D., and Conney, A. H. Inhibitory effect of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene. Carcinogenesis (Lond.), 13: 2183-2186, 1992.
11. Rao, C V , Rivenson, A , Simi, B., and Reddy, B S. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res., 55: 259-266, 1995.
12. Kujubu, D. A., Fletcher, B. S., Varnum, B. C., Lim, R. W , and Herschman, H. R TIS 10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J. Biol. Chem., 266: 12866-12872, 1991.
13. O'Banion, M. K , Sadowsky, H. B , Winn, V., and Young, DAA serum and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein. J Biol. Chem., 266: 23261-23267, 1991.
14. Lee, S. H., Soyoola, E., Chanmugam, P., Hart, S., Sun, W., Zhong, H., Liou, S., Simmons, D., and Hwang, D Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J. Biol Chem , 267: 25934-25938, 1992.
15. DuBois, R N., Awad, J., Morrow, J., Roberts, L. J , and Bishop, P R. Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-α and phorbol ester. J. Clin. Invest , 93: 493-498, 1994.
16. Rimarachin, J A., Jacobson, J A., Szabo, P., Maclouf, J., Creminon, C., and Weksler, B. B Regulation of cyclooxygenase-2 expression in aortic smooth muscle cells Arterioscler. Thromb., 14: 1021-1031, 1994
17. Hong, S L., Wheless, C M., and Levine, L. Elevated prostaglandin synthetase activity in methylcholanthrene-transformed mouse BALB/3T3. Prostaglandins, 13: 271-279, 1977.
18. Sano, H., Kawahito, Y , Wilder, R L , Hashiramoto, A , Mukai, S , Asai, K , Kimura, S., Kato, H., Kondo, M., and Hla, T. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res., 55: 3785-3789, 1995.
19. Telang, N T , Suto, A., Wong, G. Y., Osborne, M. P., and Bradlow, H L. Induction by estrogen metabolite 16α-hydroxyestrone of genotoxic damage and aberrant proliferation in mouse mammary epithelial cells. J. Natl. Cancer Inst , 84: 634-638, 1992.
20. Telang, N. T., Narayanan, R., Bradlow, H. L., and Osborne, M. P Coordinated expression of intermediate biomarkers for tumorigenic transformation in RAS-transfected mouse mammary epithelial cells. Breast Cancer Res. Treat., 18 155-163, 1991.
21. Telang, N. T., Osborne, M P., Swterlitsch, L. A , and Narayanan, R. Neoplastic transformation of mouse mammary epithelial cells by deregulated myc expression. Cell Regul , 1: 863-872, 1990.
22. Telang, N. T., Banerjee, M. R., Iyer, A. P., and Kundu, A. B. Neoplastic transformation of epithelial cells in whole mammary gland in vitro. Proc Natl. Acad. Sci USA, 76: 5886-5890, 1979.
23. Ganguly, N., Ganguly, R., Mehta, N. M., Banerjee, M. R. Growth and differentiation of hyperplastic outgrowths derived from mammary epithelial cells transformed in organ culture. J. Natl. Cancer Inst., 58: 453-463, 1982
24. Weksler, B. B. Heparin and acidic fibroblast growth factor interact to decrease prostacyclin synthesis in human endothelial cells by affecting both prostaglandin H synthase and prostacyclin synthase J. Cell. Physiol , 142, 514-522, 1990.
25. Lowry, O. H., Rosebrough, N. J , Farr, A. L., and Randell, R. J Protein measurement with the Folin phenol reagent J. Biol Chem , 193. 265-275, 1951.
26. Laemmli, U. K. Cleavage of structural proteins during the assembly of bacteriophage T4 Nature (Lond ), 227: 680-685, 1970.
27. Towbin, H., Staehelin, T , and Gordon, J. Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets: procedures and some applications. Proc Natl. Acad. Sci. USA, 76: 4350-4354, 1979
28. Habib, A., Creminon, C , Frobert, Y., Grassi, J., Pradelles, P., and Maclouf, J. Demonstration of an inducible cyclooxygenase in human endothehal cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2. J. Biol Chem , 268. 23448-23454, 1993.
29. Yang, E K., Radominska, A , Winder, B S , and Dannenberg, A. J. Dietary lipids coinduce xenobiotic metabolizing enzymes in rat liver. Biochim Biophys Acta. 1168. 52-58, 1993.
30. Chomczynski, P., and Sacchi, N Single-step method of RNA isolation by acid guanidimum thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162. 156-159, 1987.
31. Otto, J. C., DeWitt, D. L., and Smith, W. L N-glycosylation of prostaglandin endoperoxide synthases-1 and -2 and their orientations in the endoplasmic reticulum. J. Biol Chem. 268: 18234-18242, 1993
32. Hammarstrom, S., Samuelsson, B , and Bjursell, G. Prostaglandin levels in normal and transformed baby-hamster-kidney fibroblasts. Nat. New Biol., 243: 50-51, 1973
33. Ritzi, E M., and Stylos, W A. Prostaglandin production in cultures of BALB/3T3 and SV3T3 mouse fibroblasts. J Natl. Cancer Inst , 56: 529-533, 1976.
34. 2 in human breast cancer tissues is closely associated with their malignant potency Br. J Cancer, 69, 1166-1170, 1994.
35. Eberhart, C E., Coffey, R J., Radhika, A , Giardiello, F. M , Ferrercbach, S., and DuBois, R N. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas Gastroenterology, 107: 1183-1188, 1994.
36. Kargman, S. L., O'Neill, G. P., Vickers, P. J , Evans, J. F., Mancini, J. A., and Jothy, S. Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer Cancer Res., 55: 2556-2559, 1995.
37. Eling, T. E , and Curtis, J F Xenobiotic metabolism by prostaglandin H synthase. Pharmacol. & Ther., 3: 261-273, 1992
38. Goodwin, J. S., and Ceuppens, J. Regulation of the immune response by prostaglandins. J. Clin. Immunol., 3 295-314, 1983
39. Tsujii, M., and DuBois, R. N. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell, 83: 493-501, 1995
40. ElAttar, T. M. A., and Lin, H. S. Effects of retinoids and carotenoids on prostaglandin formation by oral squamous carcinoma cells. Prostaglandins Leukotnenes Essent. Fatty Acids., 43: 175-178, 1991
41. Huang, M-T., Lysz, T., Ferraro, T. Abidi, T. F., Laskin, J D , and Conney, A. H Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis Cancer Res., 51: 813-819, 1991.
42. Xie, W., Chipman, J. G., Robertson, D L., Enkson, R. L., and Simmons, D. L. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing Proc. Natl. Acad. Sci. USA, 88 2692-2696, 1991.
43. Xie, W., Fletcher, B. S., Andersen, R D., and Herschman, H. R. v-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element Mol. Cell Biol., 14 6531-6539, 1994
44. Xie, W , and Herschman, H. R. v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transciption factor. J. Biol Chem. 270: 27622-27628, 1995.
45. Garcia, A M., Rowell, C., Ackermann, K., Kowalczyk, J. J., and Lewis, M. D. Peptidomimetic inhibitors of ras farnesylation and function in whole cells. J. Biol. Chem., 268, 18415-18418, 1993.
46. Chanmugam, P., Feng, L., Liou, S , Jang, B. C , Boudreau, M., Yu. G., Lee, J. H., Kwon, H. J., Beppu, T., Yoshida, M , Xia, Y , Wilson, C. B., and Hwang, D. Radiciol, a protein tyrosine kinase inhibitor, suppresses the expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide and in experimental glomerulonephritis J Biol. Chem., 270. 5418-5426, 1995.
47. Pedraza-Alva, G., Zingg, J-M., and Jost, J-P. AP-1 binds to a putative cAMP response element of the myoD1 promoter and negatively modulates myoD1 expression in dividing myoblasts. J Biol. Chem , 269: 6978-6985, 1994.
48. Schule, R , Rangarajan, P , Yang, N., Kliewer, S., Ransone, L. J , Bolado, J., Verma, I. M., and Evans, R. M. Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad. Sci. USA, 88 6092-6096, 1991
49. Huang, T-S., Lee, S-C., and Lin, J-K Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells Proc. Natl Acad. Sci. USA, 88 5292-5296, 1991