Cyclooxygenase 2 inhibitors: Discovery, selectivity and the future

Trends in Pharmacological Sciences

Volumn 20, Issue 11, 1999, Pages 465-469

  Marnett, Lawrence J ^a   Kalgutkar, Amit S ^a  

^a A B Hancock   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; ACETYLSALICYLIC ACID; CELECOXIB; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; O (ACETOXYPHENYL)HEPT 2 YNYL SULFIDE; PROSTAGLANDIN SYNTHASE INHIBITOR; ROFECOXIB; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; DRUG CONFORMATION; ENZYME INHIBITION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN CONFORMATION;

EID: 0032702213     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(99)01385-1     Document Type: Review

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