Role of the Nitric Oxide-cGMP System in the Regulation of Ductus Arteriosus Patency in Fetal Rats

Journal of Veterinary Medical Science

Volumn 61, Issue 12, 1999, Pages 1277-1280

  Takizawa, Tatsuya ^a   Horikoshi, Emiko ^a   Kamata, Akira ^a  

^a AZABU UNIVERSITY   (Japan)

Author keywords

Ductus arteriosus; Indomethacin; Methylene blue; Nitric oxide

Indexed keywords

CYCLIC GMP; ENZYME INHIBITOR; INDOMETACIN; METHYLENE BLUE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL; ANIMAL DISEASE; ARTICLE; CESAREAN SECTION; DOSE RESPONSE; DRUG EFFECT; DUCTUS ARTERIOSUS; FEMALE; FETUS; PHYSIOLOGY; PREGNANCY; PULMONARY ARTERY; RAT; THORACIC AORTA; WISTAR RAT;

ANIMALS; AORTA, THORACIC; CESAREAN SECTION; CYCLIC GMP; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DUCTUS ARTERIOSUS; ENZYME INHIBITORS; FEMALE; FETUS; INDOMETHACIN; METHYLENE BLUE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PREGNANCY; PULMONARY ARTERY; RATS; RATS, WISTAR;

EID: 0033256614     PISSN: 7653697     EISSN: 1782155X     Source Type: Journal    
DOI: 10.1292/jvms.61.1277     Document Type: Article

References (21)

1. Abman, S. H., Chatfield, B. A., Hall, S. L. and McMurtry. I. F. 1990. Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth. Am. J. Physiol. 259: H1921-H1927.
2. Arishima, K., Yamamoto, M., Takizawa, T., Ueda, Y., Kusanagi, M. and Eguchi, Y. 1991. Onset of the constructive effect of indomelhacin on the ductus arteriosus in fetal rats. Acta Anat. 142: 231-235.
3. Arishima, K., Yamamoto, M., Takizawa, T., Somiya, H., Eguchi, Y. and Shiota, K. 1993. Effect of acute maternal alcohol consumption on the fetal ductus arteriosus. Biol. Neonate 63: 40-43.
4. 2 concentrations and patent ductus arteriosus in fetal and neonatal lambs. J. Pediatr. 97: 455-461.
5. Clyman, R. I. 1990. Developmental physiology of the ductus arteriosus. pp. 64-75. In: Fetal and Neonatal Cardiology, 1st ed. (Long, W. A. ed.), W. B. Saunders, Philadelphia.
6. Coceani, F. and Olley, P. M. 1973. The response of the ductus arteriosus to prostaglandins. Can. J. Physiol. Pharmacol. 51: 220-225.
7. Coceani, F., Kelsey, L. and Seidlitz, E. 1994. Occurrence of endothelium-derived relaxing factor-nitric oxide in the lamb ductus arteriosus. Can. J. Physiol. Pharmacol. 72: 82-88.
8. Coceani, F., Kelsey, L., Seidlitz, E., Marks, G. S., McLaughlin, B. E., Vreman, H. J., Stevenson, D. K., Rabinovitch, M. and Ackerley, C. 1997. Carbon monoxide formation in the ductus arteriosus in the lamb: implications for the regulation of muscle tone. Br. J. Pharmacol. 120: 599-608.
9. Fox, J. J., Ziegler, J. W., Ivy, D. D., Halbower, A. C., Kinsella, J. P. and Abman, S. H. 1996. Role of nitric oxide and cGMP system in regulation of ductus arteriosus tone in ovine fetus. Am. J. Physiol. 271: H2638-H2645.
10. Fullerton, D., Hahn A. R., Banerjee, A. and Harken, A. H. 1994. Pulmonary vascular smooth muscle relaxation by cGMP-versus cAMP-mediated mechanisms. J. Surg. Res. 57: 259-263.
11. Kontos, H. A. and Wei, E. P. 1993. Hydroxyl radical dependent inactivation of guanylate cyclase in cerebral arterioles by methylene blue and by LY83538. Stroke 24: 427-434.
12. Levin, D. L., Mills, L. J., Parkey, M., Garriott, J. and Campbell, W. 1979. Constriction of the fetal ductus arteriosus after administration of indomethacin to the pregnant ewe. J. Pediatr. 94: 647-650.
13. Mayer, B., Brunner, F. and Schmidt, K. 1993. Novel actions of methylene blue. Eur. Heart J. 14: 22-26.
14. Momma, K. and Takao, A. 1987. In vivo constriction of the ductus arteriosus by nonsteroidal anti-inflammatory drugs in near-term and preterm fetal rats. Pediatr. Res. 22: 567-572.
15. Moncada, S. 1992. The L-arginine: nitric oxide pathway. Acta Physiol. Scand. 145: 201-227.
16. Morita, T., Perrella, M. A., Lee, M-E. and Kourembanas, S. 1995. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc. Natl. Acad. Sci. U.S.A. 92: 1475-1479.
17. Murad, F. 1994. Regulation of cytosolic guanylyl cyclase by nitric oxide: the NO-cyclic GMP signal transduction system. Adv. Pharmacol. 26: 19-33.
18. Ribeiro, M. O., Antunes, E., de Nucci, G., Lovisolo, S. M. and Zatz, R. 1992. Chronic inhibition of nitric oxide synthesis: A new model of arterial hypertension. Hypertension 20: 298-303.
19. Smith, G. C. S. 1998. The pharmacology of the ductus arteriosus. Pharmacol. Rev. 50: 35-58.
20. Walsh, R. S. and Mentzer, R. M. 1987. Role of cyclic nucleotides in relaxation of fetal lamb ductus arteriosus. Surgery 102: 313-318.
21. Wolin, M. S., Cherry, P. D., Rodenburg, J. M., Messina, E. J. and Kaley, G. 1990. Methylene blue inhibits vasodilation of skeletal muscle arterioles to acetylcholine and nitric oxide via the extracellular generation of superoxide anion. J. Pharmacol. Exp. Ther. 254: 872-876.