-
1
-
-
0035662474
-
Dual acting anti-inflammatory drugs: A reappraisal
-
Bertolini, A., Ottani, A. & Sandrini, M. (2001) Dual acting anti-inflammatory drugs: a reappraisal. Pharmacological Research, 44, 437-450.
-
(2001)
Pharmacological Research
, vol.44
, pp. 437-450
-
-
Bertolini, A.1
Ottani, A.2
Sandrini, M.3
-
2
-
-
0041707878
-
The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy
-
Celotti, F. & Durand, T. (2003) The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy. Prostaglandins and Other Lipid Mediators, 71, 147-162.
-
(2003)
Prostaglandins and Other Lipid Mediators
, vol.71
, pp. 147-162
-
-
Celotti, F.1
Durand, T.2
-
3
-
-
0034040719
-
Pharmacokinetics. COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans
-
Depre, M., Van Ehrich, E., Hecken, A., De Lepeleire, I., Dallob, A., Wong, P., Porras, A., Gertz, B.J. & De Schepper, P.J. (2000) Pharmacokinetics. COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. European Journal of Clinical Pharmacology, 56, 167-174.
-
(2000)
European Journal of Clinical Pharmacology
, vol.56
, pp. 167-174
-
-
Depre, M.1
Van Ehrich, E.2
Hecken, A.3
De Lepeleire, I.4
Dallob, A.5
Wong, P.6
Porras, A.7
Gertz, B.J.8
De Schepper, P.J.9
-
4
-
-
0038718727
-
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin
-
Fiorucci, S., Distrutti, E., de Lima, O.M., Romano, M., Mencarelli, A., Barbanti, M., Palazzini, E., Morelli, A. & Wallace, J.L. (2003) Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin. The FASEB Journal, 17, 1171-1173.
-
(2003)
The FASEB Journal
, vol.17
, pp. 1171-1173
-
-
Fiorucci, S.1
Distrutti, E.2
De Lima, O.M.3
Romano, M.4
Mencarelli, A.5
Barbanti, M.6
Palazzini, E.7
Morelli, A.8
Wallace, J.L.9
-
5
-
-
0001392238
-
Endoscopic evaluation of the gastroduodenal mucosa following non-steroidal anti-inflammatory drug administration in the dog
-
Forsyth, S.F., Guilford, W.G. & Lawoko, C.R.O. (1996) Endoscopic evaluation of the gastroduodenal mucosa following non-steroidal anti-inflammatory drug administration in the dog. New Zealand Veterinary Journal, 44, 179-181.
-
(1996)
New Zealand Veterinary Journal
, vol.44
, pp. 179-181
-
-
Forsyth, S.F.1
Guilford, W.G.2
Lawoko, C.R.O.3
-
7
-
-
0033815066
-
The absorption, distribution, metabolism and excretion of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in rats and dogs
-
Halpin, R.A., Geer, L.A., Zhang, K.E., Marks, T.M., Dean, D.C., Jones, A.N., Melillo, D., Doss, G. & Vyas, K.P. (2000) The absorption, distribution, metabolism and excretion of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in rats and dogs. Drug Metabolism and Disposition, 28, 1244-1254.
-
(2000)
Drug Metabolism and Disposition
, vol.28
, pp. 1244-1254
-
-
Halpin, R.A.1
Geer, L.A.2
Zhang, K.E.3
Marks, T.M.4
Dean, D.C.5
Jones, A.N.6
Melillo, D.7
Doss, G.8
Vyas, K.P.9
-
8
-
-
0027294984
-
Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs
-
Hudson, N., Balsitis, M., Everitt, S. & Hawkey, C.J. (1993) Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs. Gut, 34, 742-747.
-
(1993)
Gut
, vol.34
, pp. 742-747
-
-
Hudson, N.1
Balsitis, M.2
Everitt, S.3
Hawkey, C.J.4
-
9
-
-
0034757607
-
In vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: Suppression of collagenase 1 and interleukin-1β synthesis
-
Jovanovic, D.V., Fernandes, J.C., Martel-Pelletier, J., Jolicoeur, F.C., Reboul, P., Laufer, S., Tries, S. & Pelletier, J.P. (2001) In vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: suppression of collagenase 1 and interleukin-1β synthesis. Arthritis and Rheumatism, 44, 2320-2330.
-
(2001)
Arthritis and Rheumatism
, vol.44
, pp. 2320-2330
-
-
Jovanovic, D.V.1
Fernandes, J.C.2
Martel-Pelletier, J.3
Jolicoeur, F.C.4
Reboul, P.5
Laufer, S.6
Tries, S.7
Pelletier, J.P.8
-
10
-
-
0038147318
-
Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs
-
Martel-Pelletier, J., Lajeunesse, D., Reboul, P. & Pelletier, J.P. (2003) Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs. Annals of the Rheumatic Diseases, 62, 501-509.
-
(2003)
Annals of the Rheumatic Diseases
, vol.62
, pp. 501-509
-
-
Martel-Pelletier, J.1
Lajeunesse, D.2
Reboul, P.3
Pelletier, J.P.4
-
11
-
-
0027236493
-
Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage
-
Rainsford, K.D. (1993) Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage. Agents and Actions, 39, C24-C26.
-
(1993)
Agents and Actions
, vol.39
-
-
Rainsford, K.D.1
-
12
-
-
0031680203
-
Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: Efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects
-
Simon, L.S., Lanza, F.L., Lipsky, P.E., Hubbard, R.C., Talwalker, S., Schwartz, B.D., Isakson, P.C. & Geis, G.S. (1998) Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. Arthritis and Rheumatism, 41, 1591-1602.
-
(1998)
Arthritis and Rheumatism
, vol.41
, pp. 1591-1602
-
-
Simon, L.S.1
Lanza, F.L.2
Lipsky, P.E.3
Hubbard, R.C.4
Talwalker, S.5
Schwartz, B.D.6
Isakson, P.C.7
Geis, G.S.8
-
14
-
-
0034946179
-
The pharmacological profile of ML3000: A new pyrrolizine derivative inhibiting the enzymes cyclo-oxygenase and 5-lipoxygenase
-
Tries, S. & Laufer, S. (2001) The pharmacological profile of ML3000: a new pyrrolizine derivative inhibiting the enzymes cyclo-oxygenase and 5-lipoxygenase. Inflammopharmacology, 9, 101-112.
-
(2001)
Inflammopharmacology
, vol.9
, pp. 101-112
-
-
Tries, S.1
Laufer, S.2
-
15
-
-
0028597003
-
ML 3000 reduces gastric prostaglandin synthesis without causing mucosal injury
-
Wallace, J.L., Carter, L., McKnight, W., Tries, S. & Laufer, S. (1994) ML 3000 reduces gastric prostaglandin synthesis without causing mucosal injury. European Journal of Pharmacology, 271, 525-531.
-
(1994)
European Journal of Pharmacology
, vol.271
, pp. 525-531
-
-
Wallace, J.L.1
Carter, L.2
McKnight, W.3
Tries, S.4
Laufer, S.5
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