Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib

Drug Metabolism and Disposition

Volumn 27, Issue 10, 1999, Pages 1133-1142

  Paulson, Susan K ^a   Engel, Leslie ^a   Reitz, Beverly ^a   Bolten, Suzanne ^a   Burton, Earl G ^a   Maziasz, Timothy J ^a   Yan, Bo ^a   Schoenhard, Grant L ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUFURALOL; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; CYTOCHROME P450; DRUG METABOLITE; QUINIDINE;

ANIMAL TISSUE; ARTICLE; DOG; DRUG ELIMINATION; DRUG METABOLISM; FEMALE; HUMAN; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; LIVER MICROSOME; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CLONING, MOLECULAR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; CYTOCHROME P-450 ENZYME SYSTEM; DOGS; ETHANOLAMINES; FEMALE; HUMANS; ISOENZYMES; MALE; MEMBRANE PROTEINS; MICROSOMES, LIVER; POLYMORPHISM, GENETIC; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; QUINIDINE; SULFONAMIDES;

EID: 0032853122     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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