Cyclooxygenase-2-selective inhibitors impair glomerulogenesis and renal cortical development

Kidney International

Volumn 57, Issue 2, 2000, Pages 414-422

  Kömhoff, Martin ^a,b   Wang, Jun Ling ^a,b   Cheng, Hui Fang ^a,b   Langenbach, Robert ^a,b   McKanna, James A ^a,b   Harris, Raymond C ^a,b   Breyer, Matthew D ^a,b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cyclooxygenase; Macula densa; Nephrogenesis; NSAIDs; Prostaglandins

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; SC 58560; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IMMUNOHISTOLOGY; IN SITU HYBRIDIZATION; KIDNEY CORTEX; KIDNEY DEVELOPMENT; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH MUCOSA;

EID: 0033945934     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0085-2538(15)46757-2     Document Type: Article

References (25)

1. 1. VOYER LE, DRUT R, MENDEZ JH: Fetal renal maldevelopment with oligohydramnios following maternal use of piroxicam. Pediatr Nephrol 8:592-594, 1994
2. 2. VEERSEMA D, DE JONG PA, VAN WIJCK JA: Indomethacin and the fetal renal nonfunction syndrome. Eur J Obstet Gynecol Reprod Biol 16:113-121, 1983
3. 3. NOVY MJ: Effects of indomethacin on labor, fetal oxygenation, and fetal development in rhesus monkeys. Adv Prostaglandin Thromboxane Res 4:285-300, 1978
4. 4. AVNER ED, SWEENEY WE, PIESCO NP JR, ELLIS D: Growth factor requirements of organogenesis in serum-free metanephric organ culture. In Vitro Cell Dev Biol 21:297-304, 1985
5. 5. KUJUBU DA, FLETCHER BS, VARNUM BC, LIM RW, HERSCHMAN HR: TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem 266:12866-12872, 1991
6. 6. HARRIS RC, MCKANNA JA, AKAI Y, JACOBSON HR, DUBOIS RN, BREYER MD: Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest 94: 2504-2510, 1994
7. 7. KOMHOFF M, GRONE HJ, KLEIN T, SEYBERTH HW, NUSING RM: Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: Implication for renal function. Am J Physiol 272:F460-F468, 1997
8. 8. ZHANG MZ, WANG JL, CHENG HF, HARRIS RC, MCKANNA JA: Cyclooxygenase-2 in rat nephron development. Am J Physiol 273:F994-F1002, 1997
9. 9. KHAN KN, VENTURINI CM, BUNCH RT, BRASSARD JA, KOKI AT, MORRIS DL, TRUMP BF, MAZIASZ TJ, ALDEN CL: Interspecies differences in renal localization of cyclooxygenase isoforms: Implications in nonsteroidal antiinflammatory drug-related nephrotoxicity. Toxicol Pathol 26:612-620, 1998
10. 10. LANGENBACH R, MORHAM SG, TIANO HF, LOFTIN CD, GHANAYEM BI, CHULADA PC, MAHLER JF, LEF CA, GOULDING EH, KLUCKMAN KD, KIM H, SMITHIES O: Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 83:483-492, 1995
11. 11. MORHAM SG, LANGENBACH R, LOFTIN CD, TIANO HF, VOULOUMANOS N, JENNETTE JC, MAHLER JF, KLUCKMAN KD, LEDFORD A, LEE CA, SMITHIES O: Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 83:473-482, 1995
12. 12. DINCHUK JE, CAR BD, FOCHT RJ, JOHNSTON JJ, JAFFEE BD, COVINGTON MB, CONIEL NR, ENG VM, COLLINS RJ, CZERNIAK PM, GORRY S, TRZAKOS J: Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 378:406-409, 1995
13. 13. VANE JR, BOTTING RM: Mechanism of action of nonsteroidal anti-inflammatory drugs. Am J Med 104(Suppl):2S-8S; discussion 21S-22S, 1998
14. 14. VENTURINI CM, ISAKSON P, NEEDLEMAN P: Non-steroidal anti-inflammatory drug-induced renal failure: A brief review of the role of cyclooxygenase isoforms. Curr Opin Nephrol Hypertens 7: 79-82, 1998
15. 15. DRESSLER GR: The genetic control of renal development. Curr Opin Nephrol Hypertens 4:253-257, 1995
16. 16. BREYER MD, BADR KF: Arachidonic acid metabolites and the kidney, in The Kidney (vol 1), edited by BRENNER MB, Philadelphia, W.B. Saunders, pp 754-788, 1996
17. 17. DAY NA, ATTALLAH AA, LEE JB: Letter: Presence of prostaglandin A and F in fetal kidney. Prostaglandins 5:491-493, 1974
18. 18. NIIMURA F, LABOSKY PA, KUKUCHI J, OKUBO S, YOSHIDA H, OIKAWA T, ICHIKI T, NAFTILAN AJ, FOGO A, INAGAMI T, HOGAN BLM, ICHIKAWA I: Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth factor regulation. J Clin Invest 96:2947-2954, 1995
19. 19. PENNING TD, TALLEY JJ, BERTENSHAW SR, CARTER JS, COLLINS PW, DOCTER S, GRANETO MJ, LEE LF, MALECHA JW, MIYASHIRO JM, ROGERS RS, ROGIER DJ, YU ANDERSONGD SS, BURTON EG, COGBURN JN, GREGORY SA, KOBOLDT CM, PERKINS WE, SEIBERT K, VEENHUIZEN AW, ZHANG YY, ISAKSON PC: Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). J Med Chem 40:1347-1365, 1997
20. 20. GUAN Y, CHANG M, CHO W, ZHANG Y, REDHA R, DAVIS L, CHANG S, DUBOIS RN, HAO CM, BREYER M: Cloning, expression, and regulation of rabbit cyclooxygenase-2 in renal medullary interstitial cells. Am J Physiol 273:F18-F26, 1997
21. 21. YANG T, SINGH I, PHAM H, SUN D, SMART A, SCHNERMANN JB, BRIGGS JP: Regulation of cyclooxygenase expression in the kidney by dietary salt intake. Am J Physiol 274:F481-F489, 1998
22. 22. EDWARDS RM: Effects of prostaglandins on vasoconstrictor action in isolated renal arterioles. Am J Physiol 248:F779-F784, 1985
23. 23. SMITH CJ, ZHANG Y, KOBOLDT CM, MUHAMMAD J, ZWEIFEL BS, SHAFFER A, TALLEY JJ, MASFERRER JL, SEIBERT K, ISAKSON PC: Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci USA 95:13313-13318, 1998
24. 24. POTTER EL: Normal and Abnormal Development of the Kidney. Chicago, Year Book Medical Publishers, 1972
25. 25. SAWDY RD, SLATER N, FISK DK, EDMONDS DK, BENNETI P: Use of a cyclo-oxygenase type-2-selective non-steroidal anti-inflammatory agent to prevent preterm delivery. (letter) Lancet 350:265-266, 1997