Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats

British Journal of Pharmacology

Volumn 123, Issue 5, 1998, Pages 795-804

  Schmassmann, Adrian ^a   Peskar, Brigitta M ^b   Stettler, Christian ^a   Netzer, Peter ^a   Stroff, Thomas ^a   Flogerzi, Beatrice ^a   Halter, Fred ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Anti inflammatory action; Cellular localization; Cyclo oxygenase 2; Gastric ulcer healing; Immunoreactivity; Indomethacin; L 745,337 (5 methanesulphonamido 6 (2,4 difluorothiophenyl) 1 indanone); Non steroidal anti inflammatory drugs; Prostaglandin endoperoxide synthase

Indexed keywords

6 (2,4 DIFLUOROPHENYLTHIO) 5 METHANESULFONAMIDO 1 INDANONE; 6 OXOPROSTAGLANDIN F1 ALPHA; DICLOFENAC; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; THROMBOXANE B2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DIGESTIVE SYSTEM ULCER; ENDOTHELIUM CELL; FEMALE; FIBROBLAST; GRANULATION TISSUE; IMMUNOHISTOCHEMISTRY; INTRAGASTRIC DRUG ADMINISTRATION; MACROPHAGE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; STOMACH ULCER; STOMACH WALL; SUBCUTANEOUS DRUG ADMINISTRATION; ULCER HEALING;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; CYCLOOXYGENASE INHIBITORS; DICLOFENAC; DISEASE MODELS, ANIMAL; FEMALE; ILEUM; INDANS; INDOMETHACIN; INTESTINAL DISEASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR; STOMACH ULCER; ULCER;

EID: 0031884213     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701672     Document Type: Article

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