Cyclo-oxygenase isoenzymes. Structural basis for selective inhibition of cyclo-oxygenases by anti-inflammatory agents

Digestive and Liver Disease

Volumn 33, Issue SUPPL. 2, 2001, Pages

  Fiorucci, S ^a,b   Antonelli, E ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b POLICLINICO MONTELUCE   (Italy)

Author keywords

Cyclo oxygenase; Non steroidal anti inflammatory drugs; Prostaglandin; Stomach

Indexed keywords

6 (2,4 DIFLUOROPHENYLTHIO) 5 METHANESULFONAMIDO 1 INDANONE; ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOKINE; FLURBIPROFEN; IBUPROFEN; INDOMETACIN; ISOENZYME; LEUCINE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; DRUG INDUCED DISEASE; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME STRUCTURE; ENZYME SUBSTRATE; INFLAMMATION; MUCOSAL IMMUNITY; NONHUMAN; PATHOGENESIS; PHYSIOLOGY; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT; STOMACH INJURY;

EID: 0035673517     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1590-8658(01)80152-3     Document Type: Article

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