Redundancy of biological regulation as the basis of emergence of multidrug resistance

International Review of Cytology

Volumn 246, Issue , 2005, Pages 1-29

  Shtil, Alexander A ^a   Azare, Janeen ^b  

^a N N BLOKHIN RUSSIAN CANCER RESEARCH CENTER   (Russian Federation)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Anticancer drugs; Gene expression; Multidrug resistance; P glycoprotein; Signal transduction

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ADENOSINE TRIPHOSPHATE DEPENDENT PROTEINASE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CALCIUM ION; DACTINOMYCIN; DNA METHYLTRANSFERASE INHIBITOR; HISTONE DEACETYLASE INHIBITOR; I KAPPA B; I KAPPA B KINASE GAMMA; I KAPPA B KINASE INHIBITOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MULTIDRUG RESISTANCE PROTEIN 1; PHORBOL ESTER; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PYRROLIDINE DITHIOCARBAMATE; SALICYLIC ACID DERIVATIVE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TRICHOSTATIN A; VINCRISTINE; XENOBIOTIC AGENT; CALCIUM; GLYCOPROTEIN P; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR;

CALCIUM CELL LEVEL; CELL FUNCTION; CELL SURVIVAL; CHROMATIN; GENE CONTROL; GENE OVEREXPRESSION; HUMAN; LEUKEMIA CELL LINE; MULTIDRUG RESISTANCE; NONHUMAN; NULL ALLELE; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; ENZYME ACTIVATION; GENE; GENE EXPRESSION REGULATION; GENETICS; LIPID METABOLISM; METABOLISM; PHYSIOLOGY; PROMOTER REGION;

EUKARYOTA;

ANTINEOPLASTIC AGENTS; CALCIUM; CHROMATIN; DRUG RESISTANCE, MULTIPLE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENES, MDR; HUMANS; LIPID METABOLISM; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; P-GLYCOPROTEIN; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 25144494203     PISSN: 00747696     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0074-7696(05)46001-5     Document Type: Review

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