MAP kinases contribute to IL-8 secretion by intestinal epithelial cells via a posttranscriptional mechanism

American Journal of Physiology - Cell Physiology

Volumn 283, Issue 1 52-1, 2002, Pages

  Jijon, Humberto B ^a,b   Panenka, William J ^a   Madsen, Karen L ^b   Parsons, Howard G ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Enterocyte; Intestinal inflammation; MRNA stability; Signal transduction

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 18; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL STRAIN HT29; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

EID: 0036087691     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00113.2001     Document Type: Article

References (48)

1. Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells
2. Inhibitors of transcription, proteasome inhibitors, and DNA-damaging drugs differentially affect feedback of p53 degradation
3. NF-κB-inducing kinase is a common mediator of IL-17-, TNF-α-, and IL-1β-induced chemokine promoter activation in intestinal epithelial cells
4. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors
5. mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: Different deadenylation kinetics and uncoupling from translation
6. MAP kinase pathways
7. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
8. Activation of Jun N-terminal kinase/stress-activated protein kinase pathway by tumor necrosis factor α leads to intracellular adhesion molecule-1 expression
9. Tyrosine kinase and MAPK inhibition of TNF-α- and EGF-stimulated IEC-6 cell growth
10. Expression of intercellular adhesion molecule 1 (ICAM-1, CD54) in colonic epithelial cells
11. A synthetic inhibitor of the mitogen-activated protein kinase cascade
12. Differential cytokine expression by human intestinal epithelial cell lines: Regulated expression of interleukin 8
13. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry
14. Intestinal inflammation: A complex interplay of immune and nonimmune cell interactions
15. Regulation of interleukin-8 production in a human colon epithelial cell line (HT-29)
16. mapk in proliferating cultures of epithelial cells
17. p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient
18. Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells
19. Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways
20. Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1
21. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells
22. Evidence for altered regulation of IκBα degradation in human colonic epithelial cells
23. Mediation by NF-κB of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors
24. TNF receptor-associated factor-2 is involved in both IL-1β and TNF-α signaling cascades leading to NF-κB activation and IL-8 expression in human intestinal epithelial cells
25. Epithelial cells as sensors for microbial infection
26. Tumor necrosis factor alpha regulates proliferation in a mouse intestinal cell line
27. Conversion of TNFα from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase
28. The regulation of AP-1 activity by mitogen-activated protein kinases
29. Reversion of v-H-ras-transformed NIH 3T3 cells by apigenin through inhibiting mitogen activated protein kinase and its downstream oncogenes
30. Signal transduction through MAP kinase cascades
31. Signalling by CD95 and TNF receptors: Not only life and death
32. Tumor necrosis factor-α increases sodium and chloride conductance across the tight junction of CACO-2 BBE, a human intestinal epithelial cell line
33. Tumor necrosis factor-alpha inhibits lipid and lipoprotein transport by Caco-2 cells
34. Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8
35. Cell adhesion and migration. I. Neutrophil adhesive interactions with intestinal epithelium
36. Functional characterization of a non-AUUUA AU-rich element from the c-jun protooncogene mRNA: Evidence for a novel class of AU-rich elements
37. Cytokine-induced stabilization of newly synthesized IκB-α
38. NF-κB/rel/IκB: Implication in gastrointestinal diseases
39. Effect of transcription inhibitors on the iron-dependent degradation of transferrin receptor mRNA
40. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required fir nuclear factor-κB p65 transactivation mediated by tumor necrosis factor-α
41. Review article. Chemokine production byintestinal epithelial cells: A therapeutic target in inflammatory bowel disease?
42. Protein kinase C-dependent activation of NF-κB in enterocytes is independent of IκB degradation
43. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
44. Monitoring mRNA expression by polymerase chain reaction: The "primer-dropping" method
45. Differential and regulated expression of C-X-C, C-C, and C-chemokines by human colon epithelial cells
46. Entamoeba histolytica stimulates interleukin 8 from human colonic epithelial cells without parasite-enterocyte contact
47. Regulation of TNF expression by multiple mitogen-activated protein kinase pathways
48. Rhinovirus stimulation of interleukin-8 in vivo and in vitro: Role of NF-κB