Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals

Cell

Volumn 95, Issue 3, 1998, Pages 307-318

  Oancea, Elena ^a   Meyer, Tobias ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; DIACYLGLYCEROL; GREEN FLUORESCENT PROTEIN; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; MEMBRANE BINDING; MOLECULAR BIOLOGY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; SECOND MESSENGER; SIGNAL TRANSDUCTION;

EID: 0032582525     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81763-8     Document Type: Article

References (32)

1. Abeliovich, A., Chen, C., Goda, Y., Silva, A.J., Stevens, C.F., and Tonegawa, S. (1993). Modified hippocampal long-term potentiation in PKC gamma-mutant mice. Cell 75, 1253-1262.
2. Berridge, M.J. (1993). Inositol trisphosphate and calcium signaling. Nature 361, 315-325.
3. Boni, L.T., and Rando, R.R. (1985). The nature of protein kinase C activation by physically defined phospholipid vesicles and diacylglycerols. J. Biol. Chem. 260, 10819-10825.
4. De Koninck, P., and Schulman, H. (1998). Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science 279, 227-230.
5. Dolmetsch, R.E., Xu, K., and Lewis, R.S. (1998). Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392, 933-936.
6. Hajnoczky, G., Robb-Gaspers, L.D., Seitz, M.B., and Thomas, A.P. (1995). Decoding of cytosolic calcium oscillations in the mitochondria. Cell 82, 415-424.
7. Hannun, Y.A., Loomis, C.R., and Bell, R.M. (1985). Activation of protein kinase C by Triton X-100 mixed micelles containing diacylglycerol and phosphatidylserine. J. Biol. Chem. 260, 10039-10043.
8. Hurley, J.H., and Gobler, J.A. (1997). Protein kinase C and phospholipase C: bilayer interactions and regulation. Curr. Opin. Struct. Biol. 7, 557-565.
9. Kontos, C.D., Stauffer, T.P., Yang, W.P., Huang, L., Blanar, M.A., Meyer, T., and Peters, K.G. (1998). Activation of phosphatidilinositol 3-kinase and Aky by Tie2: a potential role for Tie2 in endotelial cell survival. Mol. Cell Biol., in press.
10. Li, W.-H., Llopis, J., Whitney, M., Zlokarnik, G., Tsien, R.Y. (1998). Cell permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression. Nature 392, 936-941.
11. Meyer, T., and Stryer, L. (1991 ). Calcium spiking. Annu. Rev. Biophys. Biophys. Chem. 20, 153-174.
12. Meyer, T., Hanson, P.I., Stryer, L., and Schulman, H. (1992). Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science 256, 1199-1202.
13. Miyawaki, A., Llopis, J., Heim, R., McCaffery, J.M., Adams, J.A., Ikura, M., and Tsien, R.Y. (1997). Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature 388, 882-887.
14. Mochly-Rosen, D. (1995). Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science 268, 247-251.
15. Mosior, M., and McLaughlin, S. (1991). Peptides that mimic the pseudosubstrate region of protein kinase C bind to acidic lipids in membranes. Biophys. J. 60, 149-159.
16. Mosior, M., and Newton, A.C. (1996). Calcium-independent binding to interfacial phorbol esters causes protein kinase C to associate with membranes in the absence of acidic lipids. Biochemistry 35, 1612-1623.
17. Newton, A.C. (1995). Protein kinase C. Seeing two domains. Curr. Biol. 5, 973-976.
18. Nishizuka, Y. (1988). The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334, 661-665.
19. Nishizuka, Y. (1992). Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258, 607-614.
20. Oancea, E., Teruel, M.N., Quest, A.F.G., and Meyer, T. (1998). Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells. J. Cell Biol. 140, 485-498.
21. Pears, C.J., and Parker, P.J. (1991). Domain interactions in protein kinase C. J. Cell. Sci. 100, 683-686.
22. Quest, A.F. (1996). Regulation of protein kinase C: a tale of lipids and proteins. Enzyme Protein. 49, 231-61.
23. Romoser, V.A., Hinkle, P.M., and Persechini, A. (1997). Detection in living cells of Ca2+-dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. A new class of fluorescent indicators. J. Biol. Chem. 272, 13270-13274.
24. Sakai, N., Sasaki, K., Ikegaki, N., Shirai, Y., Ono, Y., and Saito, N. (1997). Direct visualization of the translocation of the gamma-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein. J. Cell Biol. 139, 1465-1476.
25. Schneider, H., Cohen-Dayag, A., and Pecht, I. (1992). Tyrosine phosphorylation of phospholipase C gamma 1 couples the Fc epsilon receptor mediated signal to mast cells secretion. Int. Immunol. 4, 447-453.
26. Srinivasa, N., Bax, B., Blundell, T.L., and Parker, P.J. (1996). Structural aspects of the functional modules in human protein kinase-C alpha deduced from comparative analysis. Proteins 26, 217-235.
27. Stauffer, T.P., and Meyer, T. (1997). Compartmentalized IgE receptor-mediated signal transduction in living cells. J. Cell Biol. 139, 1447-1454.
28. Stauffer, T.P., Ahn, S., and Meyer, T. (1998). Receptor induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells. Curr. Biol. 8, 343-346.
29. Teruel, M., and Meyer, T. (1997). Electroporation induced formation of calcium entry sites in cell body and processes of adherent cells. Biophys. J. 73, 1785-1796.
30. Thomas, A.P., Bird, G.S., Hajnoczky, G., Robb-Gaspers, L.D., and Putney, J.W., Jr. (1996). Spatial and temporal aspects of cellular calcium signaling. FASEB J. 10, 1505-1517.
31. Tsien, R.W., and Tsien, R.Y. (1990). Calcium channels, stores, and oscillations. Annu. Rev. Cell. Biol. 6, 715-760.
32. Yokoe, H., and Meyer, T. (1996). Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement. Nat. Biotechnol. 14, 1252-1256.